$163+ Cheap flights from Buffalo (BUF) to the Cayman Islands
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
Sep 21 — Sep 281
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Cayman Islands with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Cayman Islands
Cheapest
Best
Last-minute
One-way
Cheapest flights from Buffalo to Cayman IslandsExplore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2026.
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2026.
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:08 am -
2 stops9h 17m
Thu 10/1512:35 pm -
1 stop9h 15m
Deal found 8/21![American Airlines logo]()
$382
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:35 pm -
2 stops18h 35m
Wed 10/148:00 am -
2 stops13h 24m
Deal found 8/22![American Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:50 am -
1 stop5h 37m
Tue 9/82:10 pm -
2 stops20h 56m
Deal found 8/18![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:51 pm -
1 stop17h 39m
Tue 10/138:00 am -
2 stops12h 35m
Deal found 8/21![American Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
2 stops10h 30m
Thu 10/294:45 pm -
2 stops26h 51m
Deal found 8/17![United Airlines logo]()
$556
This FlightHub deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:45 pm -
2 stops18h 40m
Wed 10/146:05 pm -
3 stops24h 04m
Deal found 8/22![Multiple Airlines logo]()
$5,422
This Priceline deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:49 pm -
2 stops42h 06m
Tue 9/86:05 pm -
3 stops27h 05m
Deal found 8/18![Multiple Airlines logo]()
$9,497
Best flights from Buffalo to Cayman IslandsDiscover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 22, 2026.
Discover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 22, 2026.
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/36:00 am -
1 stop6h 40m
Wed 2/102:05 pm -
1 stop9h 50m
Deal found 8/18![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am -
2 stops9h 25m
Thu 10/1512:00 pm -
2 stops9h 50m
Deal found 8/21![American Airlines logo]()
$382
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:58 pm -
2 stops22h 32m
Thu 10/294:45 pm -
2 stops26h 51m
Deal found 8/21![United Airlines logo]()
$556
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:35 pm -
2 stops16h 55m
Tue 10/138:00 am -
2 stops12h 35m
Deal found 8/21![American Airlines logo]()
$382
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:35 pm -
2 stops18h 35m
Wed 10/148:00 am -
2 stops13h 24m
Deal found 8/22![American Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/36:00 am -
2 stops14h 23m
Wed 2/1012:55 pm -
2 stops9h 48m
Deal found 8/18![American Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:00 am -
2 stops7h 27m
Tue 9/82:10 pm -
2 stops20h 56m
Deal found 8/18![American Airlines logo]()
$398
Last-minute flights from Buffalo to Cayman IslandsDiscover last-minute flight deals from Buffalo to Cayman Islands. Data last updated August 22, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Cayman Islands. Data last updated August 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:50 am -
1 stop5h 37m
Tue 9/82:10 pm -
2 stops20h 56m
Deal found 8/18![American Airlines logo]()
$398
This Priceline deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:49 pm -
2 stops42h 06m
Tue 9/86:05 pm -
3 stops27h 05m
Deal found 8/18![Multiple Airlines logo]()
$9,497
One-way flights from Buffalo to Cayman IslandsSearch for one-way flight options from Buffalo to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated August 22, 2026.
Search for one-way flight options from Buffalo to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated August 22, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:00 am -
2 stops8h 10m
Deal found 8/17![American Airlines logo]()
$163
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:48 pm -
2 stops16h 51m
Deal found 8/17![Delta logo]()
$169
This KAYAK deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:51 pm -
3 stops26h 19m
Deal found 8/17![British Airways logo]()
$5,236
Find flight deals from Buffalo to Cayman Islands
Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated August 22, 2026.
Round-trip from | $377 (Delta) |
|---|---|
One-way from | $163 (American Airlines) |
Popular in | December |
Cheapest in | June |
Average price | $347 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 22, 2026.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Wed 2/3
6:00 am-12:40 pm
1 stop6h 40m
George Town Owen Roberts Intl
Wed 2/10
2:05 pm-11:55 pm
1 stop9h 50m
$377
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Tue 10/6
6:00 am-2:25 pm
2 stops9h 25m
George Town Owen Roberts Intl
Thu 10/15
12:00 pm-10:50 pm
2 stops9h 50m
$382
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Tue 10/6
7:35 pm-11:30 am
2 stops16h 55m
George Town Owen Roberts Intl
Tue 10/13
8:00 am-9:35 pm
2 stops12h 35m
$382
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Wed 10/7
7:35 pm-1:10 pm
2 stops18h 35m
George Town Owen Roberts Intl
Wed 10/14
8:00 am-10:24 pm
2 stops13h 24m
$387
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Wed 2/3
6:00 am-8:23 pm
2 stops14h 23m
George Town Owen Roberts Intl
Wed 2/10
12:55 pm-10:43 pm
2 stops9h 48m
$387
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 9/3
5:00 am-11:27 am
2 stops7h 27m
George Town Owen Roberts Intl
Tue 9/8
2:10 pm-12:06 pm
2 stops20h 56m
$398
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Tue 10/27
5:58 pm-3:30 pm
2 stops22h 32m
George Town Owen Roberts Intl
Thu 10/29
4:45 pm-8:36 pm
2 stops26h 51m
$556
Cheapest one-way
Quickest one-way
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Mon 8/31
6:50 am-11:27 am
1 stop5h 37m
$163
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Sun 8/30
6:05 am-11:39 am
1 stop6h 34m
$163
Sorted by cheapest first
Best time to book a flight from Buffalo to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
BUF-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to the Cayman Islands
BUF-KY0
BUF-GCM
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Cayman Islands
Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated August 22, 2026.
Peruse reviews from past customers who have flown with American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Boarding
7.5
Entertainment
6.8
Food
6.4
Comfort
7.2
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Overall
7.1
Boarding
7.5
Entertainment
6.8
Food
6.4
Comfort
7.2
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to Cayman Islands
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Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
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Buffalo and Cayman Islands flights
Browse other Buffalo and Cayman Islands flight options. Last updated on August 22, 2026.
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Fly to Cayman Islands regions
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Top airline flying from Buffalo to Cayman Islands
Discover the top airline that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$325 | Average$555 | FlexibilityNo cancel fee | On-time71% |