$173+ Cheap flights from Buffalo (BUF) to the Cayman Islands
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Cayman Islands with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Cayman Islands
Cheapest
Best
Last-minute
One-way
Cheapest flights from Buffalo to Cayman IslandsExplore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:08 am -
2 stops9h 17m
Tue 10/1312:35 pm -
1 stop21h 13m
Deal found 9/3![American Airlines logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:04 pm -
1 stop16h 27m
Tue 12/293:30 pm -
1 stop8h 49m
Deal found 9/3![American Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:55 pm -
2 stops19h 35m
Thu 10/294:45 pm -
2 stops26h 51m
Deal found 9/6![United Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:30 am -
1 stop5h 57m
Sun 9/1312:36 pm -
1 stop8h 59m
Deal found 9/7![American Airlines logo]()
$526
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:52 pm -
2 stops20h 08m
Tue 12/295:45 pm -
2 stops46h 19m
Deal found 9/6![United Airlines logo]()
$540
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:52 pm -
2 stops44h 08m
Wed 12/305:45 pm -
2 stops27h 02m
Deal found 9/7![United Airlines logo]()
$870
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:00 am -
1 stop6h 04m
Wed 12/3012:31 pm -
1 stop10h 28m
Deal found 9/7![American Airlines logo]()
$1,076
Best flights from Buffalo to Cayman IslandsDiscover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/286:00 am -
2 stops13h 59m
Sun 2/143:36 pm -
1 stop8h 23m
Deal found 9/4![American Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:55 pm -
2 stops19h 35m
Thu 10/294:45 pm -
2 stops26h 51m
Deal found 9/6![United Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:08 am -
2 stops9h 17m
Tue 10/1312:35 pm -
1 stop21h 13m
Deal found 9/3![American Airlines logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:04 pm -
1 stop16h 27m
Tue 12/293:30 pm -
1 stop8h 49m
Deal found 9/6![American Airlines logo]()
$447
Last-minute flights from Buffalo to Cayman IslandsDiscover last-minute flight deals from Buffalo to Cayman Islands. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Cayman Islands. Data last updated September 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:30 am -
1 stop5h 57m
Sun 9/1312:36 pm -
1 stop8h 59m
Deal found 9/7![American Airlines logo]()
$526
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:08 am -
2 stops9h 17m
Tue 10/1312:35 pm -
1 stop21h 13m
Deal found 9/3![American Airlines logo]()
$437
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:55 pm -
2 stops19h 35m
Thu 10/294:45 pm -
2 stops26h 51m
Deal found 9/6![United Airlines logo]()
$522
One-way flights from Buffalo to Cayman IslandsSearch for one-way flight options from Buffalo to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Buffalo to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:56 pm -
2 stops17h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:40 pm -
2 stops28h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/234:31 pm -
2 stops19h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:49 pm -
3 stops28h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$307
This KAYAK deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:09 pm -
3 stops53h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![British Airways logo]()
$5,251
Find flight deals from Buffalo to Cayman Islands
Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated September 7, 2026.
Round-trip from | $437 (American Airlines) |
|---|---|
One-way from | $173 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 9/24
6:56 pm-11:27 am
2 stops17h 31m
George Town Owen Roberts Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$173
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Wed 9/23
4:31 pm-11:00 am
2 stops19h 29m
George Town Owen Roberts Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$289
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 9/24
12:49 pm-4:05 pm
3 stops28h 16m
George Town Owen Roberts Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$307
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 1/28
6:00 am-7:59 pm
2 stops13h 59m
George Town Owen Roberts Intl
Sun 2/14
3:36 pm-11:59 pm
1 stop8h 23m
$407
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Tue 10/6
6:08 am-2:25 pm
2 stops9h 17m
George Town Owen Roberts Intl
Tue 10/13
12:35 pm-10:48 am
1 stop21h 13m
$437
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 12/24
7:04 pm-11:31 am
1 stop16h 27m
George Town Owen Roberts Intl
Tue 12/29
3:30 pm-12:19 am
1 stop8h 49m
$447
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Tue 10/27
8:55 pm-3:30 pm
2 stops19h 35m
George Town Owen Roberts Intl
Thu 10/29
4:45 pm-8:36 pm
2 stops26h 51m
$522
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Wed 9/23
12:09 pm-4:10 pm
3 stops53h 01m
George Town Owen Roberts Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$5,251
Sorted by cheapest first
Best time to book a flight from Buffalo to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
BUF-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to the Cayman Islands
BUF-KY0
BUF-GCM
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Cayman Islands
Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated September 7, 2026.
Peruse reviews from past customers who have flown with American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Entertainment
6.8
Overall
7.1
Crew
7.9
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Food
6.4
Entertainment
6.8
Overall
7.1
Crew
7.9
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to Cayman Islands
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Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
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Buffalo and Cayman Islands flights
Browse other Buffalo and Cayman Islands flight options. Last updated on September 7, 2026.
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Top airline flying from Buffalo to Cayman Islands
Discover the top airline that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$325 | Average$555 | FlexibilityNo cancel fee | On-time71% |