$444+ Cheap flights from Buffalo (BUF) to the Cayman Islands
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Cayman Islands with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Cayman Islands
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Best
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Cheapest flights from Buffalo to Cayman IslandsExplore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:01 pm -
1 stop17h 24m
Mon 11/1612:55 pm -
2 stops11h 04m
Deal found 10/19![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:37 pm -
1 stop15h 46m
Tue 11/1712:18 pm -
1 stop9h 22m
Deal found 10/15![American Airlines logo]()
$458
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:45 am -
1 stop12h 08m
Tue 12/295:45 pm -
1 stop16h 32m
Deal found 10/15![American Airlines logo]()
$468
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:15 am -
1 stop6h 57m
Tue 12/292:27 pm -
1 stop9h 28m
Deal found 10/19![Delta logo]()
$550
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:59 pm -
2 stops19h 13m
Sat 12/2612:55 pm -
1 stop11h 07m
Deal found 10/16![Delta logo]()
$552
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:53 pm -
2 stops16h 07m
Fri 10/3012:00 pm -
2 stops9h 50m
Deal found 10/19![American Airlines logo]()
$554
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:04 am -
1 stop10h 41m
Thu 12/248:25 am -
1 stop15h 24m
Deal found 10/16![American Airlines logo]()
$560
Best flights from Buffalo to Cayman IslandsDiscover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:00 am -
2 stops13h 50m
Mon 1/2512:48 pm -
2 stops9h 35m
Deal found 10/19![American Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:00 am -
1 stop5h 58m
Tue 12/292:27 pm -
2 stops9h 35m
Deal found 10/18![Delta logo]()
$462
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2710:20 am -
1 stop6h 15m
Sat 3/65:15 pm -
1 stop16h 32m
Deal found 10/17![United Airlines logo]()
$513
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:03 am -
2 stops12h 47m
Mon 1/2512:48 pm -
2 stops10h 08m
Deal found 10/19![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:45 am -
1 stop12h 08m
Tue 12/295:45 pm -
1 stop16h 32m
Deal found 10/15![American Airlines logo]()
$468
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:35 pm -
1 stop20h 10m
Thu 12/245:45 pm -
2 stops27h 02m
Deal found 10/16![United Airlines logo]()
$580
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/66:49 am -
2 stops12h 59m
Sat 3/1312:49 pm -
2 stops9h 09m
Deal found 10/15![American Airlines logo]()
$537
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2710:20 am -
1 stop6h 15m
Wed 3/32:25 pm -
2 stops19h 22m
Deal found 10/18![United Airlines logo]()
$592
Last-minute flights from Buffalo to Cayman IslandsDiscover last-minute flight deals from Buffalo to Cayman Islands. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Cayman Islands. Data last updated October 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:53 pm -
2 stops16h 07m
Fri 10/3012:00 pm -
2 stops9h 50m
Deal found 10/19![American Airlines logo]()
$554
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop6h 40m
Fri 10/3012:55 pm -
1 stop10h 04m
Deal found 10/19![Delta logo]()
$824
This Mytrip deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:44 pm -
3 stops22h 51m
Fri 10/304:45 pm -
3 stops43h 14m
Deal found 10/19![Multiple Airlines logo]()
$1,280
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:37 pm -
1 stop15h 46m
Tue 11/1712:18 pm -
1 stop9h 22m
Deal found 10/15![American Airlines logo]()
$458
This Mytrip deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:02 pm -
3 stops20h 03m
Tue 11/1711:30 am -
2 stops25h 45m
Deal found 10/15![Multiple Airlines logo]()
$706
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:01 pm -
1 stop17h 24m
Mon 11/1612:55 pm -
2 stops11h 04m
Deal found 10/19![American Airlines logo]()
$446
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:05 am -
1 stop7h 30m
Mon 11/161:30 pm -
1 stop8h 55m
Deal found 10/18![Southwest logo]()
$704
Find flight deals from Buffalo to Cayman Islands
Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated October 19, 2026.
Round-trip from | $422 (American Airlines) |
|---|---|
Popular in | October |
Cheapest in | June |
Average price | $826 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 1/21
6:00 am-7:50 pm
2 stops13h 50m
George Town Owen Roberts Intl
Mon 1/25
12:48 pm-10:23 pm
2 stops9h 35m
$444
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Wed 1/20
7:03 am-7:50 pm
2 stops12h 47m
George Town Owen Roberts Intl
Mon 1/25
12:48 pm-10:56 pm
2 stops10h 08m
$449
Quickest round-trip
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 12/24
6:00 am-11:58 am
1 stop5h 58m
George Town Owen Roberts Intl
Tue 12/29
2:27 pm-12:02 am
2 stops9h 35m
$462
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 12/24
7:45 am-7:53 pm
1 stop12h 08m
George Town Owen Roberts Intl
Tue 12/29
5:45 pm-10:17 am
1 stop16h 32m
$468
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Sat 2/27
10:20 am-4:35 pm
1 stop6h 15m
George Town Owen Roberts Intl
Sat 3/6
5:15 pm-9:47 am
1 stop16h 32m
$513
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Sat 3/6
6:49 am-7:48 pm
2 stops12h 59m
George Town Owen Roberts Intl
Sat 3/13
12:49 pm-9:58 pm
2 stops9h 09m
$537
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Mon 12/21
5:35 pm-1:45 pm
1 stop20h 10m
George Town Owen Roberts Intl
Thu 12/24
5:45 pm-8:47 pm
2 stops27h 02m
$580
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Sat 2/27
10:20 am-4:35 pm
1 stop6h 15m
George Town Owen Roberts Intl
Wed 3/3
2:25 pm-9:47 am
2 stops19h 22m
$592
Sorted by cheapest first
Best time to book a flight from Buffalo to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
BUF-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to the Cayman Islands
BUF-KY0
BUF-GCM
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Cayman Islands
Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated October 19, 2026.
Peruse reviews from past customers who have flown with American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Food
6.4
Boarding
7.4
Comfort
7.1
Entertainment
6.8
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Crew
7.9
Food
6.4
Boarding
7.4
Comfort
7.1
Entertainment
6.8
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to Cayman Islands
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Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
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Buffalo and Cayman Islands flights
Browse other Buffalo and Cayman Islands flight options. Last updated on October 19, 2026.
Popular flight searches
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Fly to Cayman Islands regions
Consider these flights traveling to Cayman Islands regions.
Top airline flying from Buffalo to Cayman Islands
Discover the top airline that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$325 | Average$555 | FlexibilityNo cancel fee | On-time71% |