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Cayman Islands

$297+ Cheap flights from Buffalo (BUF) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Buffalo to Cayman Islands

Cheapest flights from Buffalo to Cayman Islands
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:45 pm
BUF
-
GCM
1 stop15h 38m
American Airlines
Tue 2/243:35 pm
GCM
-
BUF
1 stop8h 05m
American Airlines
Deal found 1/21$297
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:05 am
BUF
-
GCM
1 stop8h 30m
American Airlines
Sat 3/74:00 pm
GCM
-
BUF
1 stop7h 23m
American Airlines
Deal found 1/21$298
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:20 pm
BUF
-
GCM
1 stop19h 04m
American Airlines
Mon 12/143:14 pm
GCM
-
BUF
1 stop8h 53m
American Airlines
Deal found 1/21$304
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/77:00 am
BUF
-
GCM
1 stop6h 45m
United Airlines
Sat 3/144:30 pm
GCM
-
BUF
1 stop6h 12m
United Airlines
Deal found 1/20$357
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:30 pm
BUF
-
GCM
2 stops17h 15m
United Airlines
Mon 3/234:45 pm
GCM
-
BUF
2 stops19h 32m
United Airlines
Deal found 1/21$362
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:02 pm
BUF
-
GCM
2 stops26h 13m
American Airlines
Sun 3/2211:40 am
GCM
-
BUF
2 stops22h 18m
American Airlines
Deal found 1/20$367
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:00 am
BUF
-
GCM
1 stop6h 45m
United Airlines
Wed 3/42:25 pm
GCM
-
BUF
2 stops33h 17m
United Airlines
Deal found 1/20$424
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:50 am
BUF
-
GCM
2 stops29h 40m
United Airlines
Mon 12/145:45 pm
GCM
-
BUF
2 stops23h 02m
United Airlines
Deal found 1/21$427
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:00 am
BUF
-
GCM
2 stops31h 45m
United Airlines
Thu 2/262:25 pm
GCM
-
BUF
2 stops33h 19m
United Airlines
Deal found 1/20$432

Find flight deals from Buffalo to Cayman Islands

Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$297
(American Airlines)

Popular in

July

Cheapest in

May

Average price

$548
Provider with most accurate pricing for Buffalo-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-George Town Owen Roberts Intl flights.
Search Deals
From Buffalo to Cayman Islands
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.

Fly from

Buffalo

Fly to

Cayman Islands

Route

Depart

Return

Price

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sun 2/22

7:00 am-1:45 pm

1 stop6h 45m

George Town Owen Roberts Intl

Thu 2/26

2:50 pm-11:59 pm

1 stop9h 09m

$297

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Mon 3/2

6:05 am-2:35 pm

1 stop8h 30m

George Town Owen Roberts Intl

Sat 3/7

4:00 pm-11:23 pm

1 stop7h 23m

$298

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Fri 3/20

6:00 am-12:15 pm

1 stop7h 15m

George Town Owen Roberts Intl

Mon 3/23

4:45 pm-4:42 pm

2 stops22h 57m

$302

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sun 2/22

7:41 pm-12:08 pm

1 stop16h 27m

George Town Owen Roberts Intl

Thu 2/26

8:45 am-11:50 pm

2 stops15h 05m

$302

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Fri 2/20

6:05 am-2:35 pm

1 stop8h 30m

George Town Owen Roberts Intl

Tue 2/24

8:45 am-11:40 pm

2 stops14h 55m

$302

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sat 3/7

7:00 am-1:45 pm

1 stop6h 45m

George Town Owen Roberts Intl

Sat 3/14

4:30 pm-11:42 pm

1 stop6h 12m

$357

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Thu 3/12

6:02 pm-7:15 pm

2 stops26h 13m

George Town Owen Roberts Intl

Sun 3/22

11:40 am-10:58 am

2 stops22h 18m

$367

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sun 3/1

7:00 am-1:45 pm

1 stop6h 45m

George Town Owen Roberts Intl

Wed 3/4

2:25 pm-11:42 pm

2 stops33h 17m

$424

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Best time to book a flight from Buffalo to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to the Cayman Islands
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated January 21, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,089 reviews

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,089 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Cayman Islands?

    Located just 8.3 mi from the city center, Buffalo (BUF) is the airport most travelers will use when flying to Cayman Islands from Buffalo.

  • How long is the flight from Buffalo to Cayman Islands?

    A quick flight from Buffalo to Cayman Islands can take about 6h 45m. United Airlines provides one of the quickest options available for as low as $297. The distance between Buffalo and Cayman Islands is about 1640 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Buffalo to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Buffalo to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Cayman Islands.

  • Can I find deals for business class flights from Buffalo to Cayman Islands?

    Yes. Cheapflights offers flight deals from Buffalo to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Buffalo to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Buffalo to Cayman Islands

Discover the top 2 airlines that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$339Average$543FlexibilityNo cancel feeOn-time71%
DeltaCheapest$435Average$593FlexibilityNo cancel feeOn-timeN/A

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