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Cayman Islands

$103+ Cheap flights from Buffalo (BUF) to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheap flight deals from Buffalo to Cayman Islands

Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$315
(American Airlines)

One-way from

$103
(United Airlines)

Popular in

July

Cheapest in

May

Average price

$624
Provider with most accurate pricing for Buffalo-George Town Owen Roberts Intl flight deals.
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Provider most trusted by Cheapflights users for Buffalo-George Town Owen Roberts Intl flights.
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From Buffalo to Cayman Islands
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One-way flight from Buffalo to Cayman Islands
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Highest demand for flights based on searches. 8% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Buffalo to Cayman Islands

Cheapest flights from Buffalo to Cayman Islands
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:46 pmBUF - GCM
2 stops19h 14mAmerican Airlines
Sat 12/134:09 pmGCM - BUF
1 stop7h 30mAmerican Airlines
Deal found 11/25$333
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:00 amBUF - GCM
1 stop8h 21mAmerican Airlines
Tue 12/3012:55 pmGCM - BUF
2 stops9h 49mAmerican Airlines
Deal found 11/25$340
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:40 pmBUF - GCM
2 stops22h 50mUnited Airlines
Sat 12/135:30 pmGCM - BUF
2 stops17h 17mUnited Airlines
Deal found 11/25$346
This JetBlue deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:45 amBUF - GCM
1 stop7h 10mJetBlue
Thu 12/113:25 pmGCM - BUF
1 stop6h 47mJetBlue
Deal found 11/24$359
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:34 pmBUF - GCM
2 stops20h 50mAmerican Airlines
Thu 12/1112:50 pmGCM - BUF
1 stop11h 17mAmerican Airlines
Deal found 11/24$393
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:48 pmBUF - GCM
2 stops17h 57mUnited Airlines
Tue 12/305:45 pmGCM - BUF
2 stops27h 09mUnited Airlines
Deal found 11/25$425
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:30 amBUF - GCM
2 stops30h 00mUnited Airlines
Sun 12/72:25 pmGCM - BUF
1 stop9h 09mUnited Airlines
Deal found 11/24$428
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amBUF - GCM
1 stop8h 24mAmerican Airlines
Sun 12/73:14 pmGCM - BUF
1 stop8h 53mAmerican Airlines
Deal found 11/24$455
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amBUF - GCM
1 stop6h 40mDelta
Thu 12/111:50 pmGCM - BUF
1 stop10h 09mDelta
Deal found 11/23$484

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.

Fly from

Buffalo

Fly to

Cayman Islands

Route

Depart

Return

Price

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Wed 2/25

6:00 am-2:33 pm

1 stop8h 33m

George Town Owen Roberts Intl

Tue 3/3

8:45 am-10:37 pm

2 stops13h 52m

$315

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sat 1/17

6:00 am-1:15 pm

1 stop7h 15m

George Town Owen Roberts Intl

Sat 1/24

5:45 pm-2:14 pm

2 stops20h 29m

$315

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Tue 12/23

6:00 am-2:21 pm

1 stop8h 21m

George Town Owen Roberts Intl

Tue 12/30

12:55 pm-11:59 pm

1 stop11h 04m

$335

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Wed 12/10

12:57 pm-2:24 pm

1 stop25h 27m

George Town Owen Roberts Intl

Sat 12/13

1:01 pm-10:54 pm

1 stop9h 53m

$335

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Mon 2/16

6:00 am-2:33 pm

1 stop8h 33m

George Town Owen Roberts Intl

Sun 2/22

3:36 pm-12:04 pm

1 stop20h 28m

$339

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sat 1/17

6:32 pm-11:50 am

2 stops17h 18m

George Town Owen Roberts Intl

Sat 1/24

3:45 pm-11:21 am

2 stops19h 36m

$340

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sun 2/15

7:32 pm-11:49 am

2 stops16h 17m

George Town Owen Roberts Intl

Sun 2/22

3:36 pm-11:16 pm

1 stop7h 40m

$345

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Wed 12/10

5:40 pm-4:30 pm

2 stops22h 50m

George Town Owen Roberts Intl

Sat 12/13

5:30 pm-10:47 am

2 stops17h 17m

$346

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sat 1/17

6:00 am-1:15 pm

1 stop7h 15m

$103

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sat 1/17

5:00 pm-11:26 am

2 stops18h 26m

$128

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/25

Showing 1-10 of 13 results
1
2

Best time to book a flight from Buffalo to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to the Cayman Islands
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated November 26, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,038 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Cayman Islands?

    Located just 8.3 mi from the city center, Buffalo (BUF) is the airport most travelers will use when flying to Cayman Islands from Buffalo.

  • How long is the flight from Buffalo to Cayman Islands?

    A quick flight from Buffalo to Cayman Islands can take about 7h 15m. American Airlines provides one of the quickest options available for as low as $315. The distance between Buffalo and Cayman Islands is about 1640 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Buffalo to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Buffalo to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Cayman Islands.

  • Can I find deals for business class flights from Buffalo to Cayman Islands?

    Yes. Cheapflights offers flight deals from Buffalo to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Buffalo to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Buffalo to Cayman Islands

Discover the top 2 airlines that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$339Average$550FlexibilityNo cancel feeOn-time71%
DeltaCheapest$414Average$471FlexibilityNo cancel feeOn-timeN/A

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