$108+ Cheap flights from Buffalo (BUF) to the Cayman Islands
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
May 24 — May 311
Round-trip
1 adult, Economy
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Cheapest flights from Buffalo to Cayman IslandsExplore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:15 am
BUF
- GCM
1 stop7h 00m
American Airlines
Sat 11/142:00 pm
GCM
- BUF
1 stop9h 36m
American Airlines
Deal found 4/21![American Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:31 pm
BUF
- GCM
2 stops16h 24m
American Airlines
Tue 6/95:12 pm
GCM
- BUF
2 stops18h 07m
American Airlines
Deal found 4/22![American Airlines logo]()
$326
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:26 pm
BUF
- GCM
1 stop20h 30m
American Airlines
Tue 11/104:10 pm
GCM
- BUF
1 stop7h 58m
American Airlines
Deal found 4/22![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
BUF
- GCM
1 stop6h 31m
American Airlines
Mon 4/2712:35 pm
GCM
- BUF
1 stop10h 12m
American Airlines
Deal found 4/21![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:34 pm
BUF
- GCM
2 stops16h 27m
American Airlines
Tue 7/145:12 pm
GCM
- BUF
2 stops19h 17m
American Airlines
Deal found 4/21![American Airlines logo]()
$331
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/284:49 pm
BUF
- GCM
1 stop23h 19m
American Airlines
Tue 9/12:10 pm
GCM
- BUF
2 stops20h 56m
American Airlines
Deal found 4/21![American Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am
BUF
- GCM
1 stop6h 45m
United Airlines
Sat 11/145:45 pm
GCM
- BUF
2 stops16h 04m
United Airlines
Deal found 4/21![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:28 pm
BUF
- GCM
2 stops16h 33m
American Airlines
Sat 5/2312:31 pm
GCM
- BUF
1 stop8h 30m
American Airlines
Deal found 4/21![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:31 pm
BUF
- GCM
1 stop16h 59m
American Airlines
Wed 7/12:42 pm
GCM
- BUF
2 stops30h 48m
American Airlines
Deal found 4/24![American Airlines logo]()
$382
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:00 am
BUF
- GCM
1 stop6h 45m
United Airlines
Thu 12/172:25 pm
GCM
- BUF
1 stop8h 12m
United Airlines
Deal found 4/22![United Airlines logo]()
$391
Best flights from Buffalo to Cayman IslandsDiscover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
Discover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:40 pm
BUF
- GCM
1 stop17h 00m
American Airlines
Tue 6/95:12 pm
GCM
- BUF
2 stops16h 40m
American Airlines
Deal found 4/22![American Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:00 am
BUF
- GCM
1 stop6h 34m
Delta
Tue 6/3012:59 pm
GCM
- BUF
1 stop10h 00m
Delta
Deal found 4/24![Delta logo]()
$467
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:34 pm
BUF
- GCM
1 stop16h 51m
American Airlines
Tue 7/142:45 pm
GCM
- BUF
2 stops17h 47m
American Airlines
Deal found 4/20![American Airlines logo]()
$331
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 am
BUF
- GCM
1 stop10h 05m
United Airlines
Sat 8/221:35 pm
GCM
- BUF
2 stops18h 39m
United Airlines
Deal found 4/20![United Airlines logo]()
$718
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:37 pm
BUF
- GCM
2 stops16h 53m
American Airlines
Sat 8/224:15 pm
GCM
- BUF
2 stops17h 39m
American Airlines
Deal found 4/19![American Airlines logo]()
$430
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:00 am
BUF
- GCM
1 stop6h 31m
Delta
Fri 8/1412:56 pm
GCM
- BUF
1 stop10h 02m
Delta
Deal found 4/20![Delta logo]()
$721
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
BUF
- GCM
1 stop6h 31m
Delta
Sun 8/1612:56 pm
GCM
- BUF
1 stop10h 02m
Delta
Deal found 4/20![Delta logo]()
$823
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 am
BUF
- GCM
1 stop6h 41m
Delta
Fri 8/2112:56 pm
GCM
- BUF
1 stop10h 02m
Delta
Deal found 4/20![Delta logo]()
$863
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:00 am
BUF
- GCM
1 stop6h 31m
Delta
Sun 8/1612:56 pm
GCM
- BUF
1 stop10h 02m
Delta
Deal found 4/20![Delta logo]()
$863
Last-minute flights from Buffalo to Cayman IslandsDiscover last-minute flight deals from Buffalo to Cayman Islands. Data last updated April 24, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Cayman Islands. Data last updated April 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
BUF
- GCM
1 stop6h 31m
American Airlines
Mon 4/2712:35 pm
GCM
- BUF
1 stop10h 12m
American Airlines
Deal found 4/21![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:28 pm
BUF
- GCM
1 stop17h 03m
American Airlines
Mon 5/412:35 pm
GCM
- BUF
1 stop10h 12m
American Airlines
Deal found 4/22![American Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:50 pm
BUF
- GCM
2 stops17h 40m
United Airlines
Sun 5/101:35 pm
GCM
- BUF
2 stops19h 18m
United Airlines
Deal found 4/24![United Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 pm
BUF
- GCM
2 stops18h 31m
American Airlines
Sun 5/1012:35 pm
GCM
- BUF
1 stop10h 15m
American Airlines
Deal found 4/24![American Airlines logo]()
$444
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:28 pm
BUF
- GCM
2 stops16h 33m
American Airlines
Sat 5/2312:31 pm
GCM
- BUF
2 stops10h 38m
American Airlines
Deal found 4/21![American Airlines logo]()
$381
One-way flights from Buffalo to Cayman IslandsSearch for one-way flight options from Buffalo to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
Search for one-way flight options from Buffalo to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:52 pm
BUF
- GCM
2 stops18h 38m
United Airlines
Deal found 4/23![United Airlines logo]()
$108
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:40 pm
BUF
- GCM
1 stop17h 00m
American Airlines
Deal found 4/23![American Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:49 pm
BUF
- GCM
3 stops25h 01m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:49 pm
BUF
- GCM
3 stops25h 01m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$193
This FlightHub deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:52 pm
BUF
- GCM
1 stop23h 12m
JetBlue
Deal found 4/23![JetBlue logo]()
$205
This FlightHub deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:05 am
BUF
- GCM
1 stop7h 59m
JetBlue
Deal found 4/19![JetBlue logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:52 pm
BUF
- GCM
3 stops40h 43m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$291
Find flight deals from Buffalo to Cayman Islands
Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated April 24, 2026.
Round-trip from | $326 (American Airlines) |
|---|---|
One-way from | $108 (United Airlines) |
Popular in | December |
Cheapest in | January |
Average price | $642 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Fri 6/5
7:40 pm-11:40 am
1 stop17h 00m
George Town Owen Roberts Intl
Tue 6/9
5:12 pm-10:52 am
2 stops16h 40m
$326
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Wed 7/8
7:34 pm-11:25 am
1 stop16h 51m
George Town Owen Roberts Intl
Tue 7/14
2:45 pm-9:32 am
2 stops17h 47m
$331
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sat 8/15
7:37 pm-11:30 am
2 stops16h 53m
George Town Owen Roberts Intl
Sat 8/22
4:15 pm-10:54 am
2 stops17h 39m
$430
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sat 6/27
6:00 am-11:34 am
1 stop6h 34m
George Town Owen Roberts Intl
Tue 6/30
12:59 pm-11:59 pm
1 stop10h 00m
$467
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sat 8/15
6:00 am-3:05 pm
1 stop10h 05m
George Town Owen Roberts Intl
Sat 8/22
1:35 pm-9:14 am
2 stops18h 39m
$718
Quickest round-trip
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sat 8/8
6:00 am-11:31 am
1 stop6h 31m
George Town Owen Roberts Intl
Fri 8/14
12:56 pm-11:58 pm
1 stop10h 02m
$721
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Fri 8/7
6:00 am-11:31 am
1 stop6h 31m
George Town Owen Roberts Intl
Sun 8/16
12:56 pm-11:58 pm
1 stop10h 02m
$823
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sat 8/15
6:00 am-11:41 am
1 stop6h 41m
George Town Owen Roberts Intl
Fri 8/21
12:56 pm-11:58 pm
1 stop10h 02m
$863
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sun 8/9
6:00 am-11:31 am
1 stop6h 31m
George Town Owen Roberts Intl
Sun 8/16
12:56 pm-11:58 pm
1 stop10h 02m
$863
Cheapest one-way
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Fri 5/29
5:41 pm-11:54 am
2 stops19h 13m
$108
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Buffalo to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
BUF-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to the Cayman Islands
BUF-KY0
BUF-GCM
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Cayman Islands
Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated April 24, 2026.
Peruse reviews from past customers who have flown with American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Overall
7.1
Comfort
7.2
Food
6.4
Boarding
7.5
Crew
7.9
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Entertainment
6.9
Overall
7.1
Comfort
7.2
Food
6.4
Boarding
7.5
Crew
7.9
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
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Buffalo and Cayman Islands flights
Browse other Buffalo and Cayman Islands flight options. Last updated on April 24, 2026.
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Fly to Cayman Islands regions
Consider these flights traveling to Cayman Islands regions.
Top airline flying from Buffalo to Cayman Islands
Discover the top airline that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$339 | Average$555 | FlexibilityNo cancel fee | On-time71% |