$108+ Cheap flights from Buffalo (BUF) to the Cayman Islands
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
May 31 — Jun 71
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Cayman Islands with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Cayman Islands
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Best
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Cheapest flights from Buffalo to Cayman IslandsExplore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:30 pm
BUF
- GCM
2 stops16h 31m
American Airlines
Thu 6/115:12 pm
GCM
- BUF
2 stops16h 07m
American Airlines
Deal found 4/28![American Airlines logo]()
$326
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:00 am
BUF
- GCM
2 stops12h 10m
American Airlines
Tue 7/145:10 pm
GCM
- BUF
2 stops19h 26m
American Airlines
Deal found 5/1![American Airlines logo]()
$331
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 am
BUF
- GCM
1 stop7h 44m
American Airlines
Sat 5/1612:40 pm
GCM
- BUF
1 stop10h 09m
American Airlines
Deal found 4/30![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:36 am
BUF
- GCM
2 stops10h 31m
American Airlines
Tue 6/3012:01 pm
GCM
- BUF
2 stops20h 28m
American Airlines
Deal found 4/29![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
BUF
- GCM
1 stop6h 31m
American Airlines
Sat 5/1612:40 pm
GCM
- BUF
1 stop10h 09m
American Airlines
Deal found 4/30![American Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:15 pm
BUF
- GCM
2 stops16h 32m
American Airlines
Sat 12/267:30 am
GCM
- BUF
2 stops16h 02m
American Airlines
Deal found 4/27![American Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:50 am
BUF
- GCM
1 stop5h 40m
American Airlines
Tue 9/12:10 pm
GCM
- BUF
2 stops18h 25m
American Airlines
Deal found 4/29![American Airlines logo]()
$430
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:05 am
BUF
- GCM
1 stop7h 10m
American Airlines
Sat 12/191:10 pm
GCM
- BUF
1 stop21h 55m
American Airlines
Deal found 5/1![American Airlines logo]()
$443
Best flights from Buffalo to Cayman IslandsDiscover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
BUF
- GCM
1 stop6h 25m
American Airlines
Tue 7/145:10 pm
GCM
- BUF
2 stops17h 01m
American Airlines
Deal found 4/30![American Airlines logo]()
$445
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
BUF
- GCM
1 stop6h 31m
Delta
Tue 7/1412:56 pm
GCM
- BUF
1 stop10h 03m
Delta
Deal found 5/1![Delta logo]()
$476
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:00 am
BUF
- GCM
2 stops30h 30m
United Airlines
Sat 8/84:45 pm
GCM
- BUF
2 stops30h 14m
United Airlines
Deal found 4/27![United Airlines logo]()
$532
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:00 am
BUF
- GCM
2 stops30h 30m
United Airlines
Sat 7/41:35 pm
GCM
- BUF
2 stops26h 17m
United Airlines
Deal found 4/29![United Airlines logo]()
$603
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:35 pm
BUF
- GCM
1 stop16h 50m
American Airlines
Sat 8/84:15 pm
GCM
- BUF
2 stops19h 23m
American Airlines
Deal found 4/28![American Airlines logo]()
$630
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:12 pm
BUF
- GCM
1 stop19h 22m
Delta
Mon 7/612:59 pm
GCM
- BUF
1 stop10h 00m
Delta
Deal found 4/29![Delta logo]()
$680
Last-minute flights from Buffalo to Cayman IslandsDiscover last-minute flight deals from Buffalo to Cayman Islands. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Cayman Islands. Data last updated May 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
BUF
- GCM
1 stop6h 31m
American Airlines
Sat 5/1612:40 pm
GCM
- BUF
1 stop10h 09m
American Airlines
Deal found 4/30![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:02 am
BUF
- GCM
2 stops26h 28m
United Airlines
Sat 5/164:15 pm
GCM
- BUF
1 stop6h 40m
United Airlines
Deal found 4/30![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:02 am
BUF
- GCM
1 stop27h 28m
United Airlines
Fri 5/151:35 pm
GCM
- BUF
2 stops19h 07m
United Airlines
Deal found 4/30![United Airlines logo]()
$461
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:41 pm
BUF
- GCM
2 stops19h 13m
Delta
Sat 5/161:19 pm
GCM
- BUF
2 stops18h 01m
Delta
Deal found 4/30![Delta logo]()
$510
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
BUF
- GCM
1 stop6h 31m
American Airlines
Fri 5/1512:35 pm
GCM
- BUF
1 stop10h 15m
American Airlines
Deal found 4/30![American Airlines logo]()
$534
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 am
BUF
- GCM
1 stop7h 44m
American Airlines
Sat 5/1612:40 pm
GCM
- BUF
1 stop10h 09m
American Airlines
Deal found 4/30![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:50 pm
BUF
- GCM
2 stops17h 40m
United Airlines
Sat 5/164:15 pm
GCM
- BUF
2 stops16h 27m
United Airlines
Deal found 4/30![United Airlines logo]()
$554
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:10 am
BUF
- GCM
2 stops31h 20m
United Airlines
Fri 5/151:35 pm
GCM
- BUF
2 stops19h 07m
United Airlines
Deal found 4/30![United Airlines logo]()
$470
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
BUF
- GCM
1 stop6h 31m
American Airlines
Fri 5/152:10 pm
GCM
- BUF
2 stops8h 40m
American Airlines
Deal found 4/30![American Airlines logo]()
$590
This FlightHub deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:16 pm
BUF
- GCM
1 stop19h 44m
JetBlue
Sat 5/302:20 pm
GCM
- BUF
1 stop25h 59m
JetBlue
Deal found 4/30![JetBlue logo]()
$729
This FlightHub deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:00 am
BUF
- GCM
1 stop8h 00m
JetBlue
Sat 5/302:20 pm
GCM
- BUF
1 stop25h 59m
JetBlue
Deal found 4/30![JetBlue logo]()
$679
One-way flights from Buffalo to Cayman IslandsSearch for one-way flight options from Buffalo to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from Buffalo to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:00 am
BUF
- GCM
1 stop7h 30m
United Airlines
Deal found 4/28![United Airlines logo]()
$108
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:30 pm
BUF
- GCM
2 stops16h 31m
American Airlines
Deal found 4/28![American Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:52 pm
BUF
- GCM
3 stops40h 43m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$297
Find flight deals from Buffalo to Cayman Islands
Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated May 1, 2026.
Round-trip from | $326 (American Airlines) |
|---|---|
One-way from | $108 (United Airlines) |
Popular in | December |
Cheapest in | January |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Wed 7/8
6:00 am-11:25 am
1 stop6h 25m
George Town Owen Roberts Intl
Tue 7/14
5:10 pm-11:11 am
2 stops17h 01m
$445
Quickest round-trip
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Wed 7/8
6:00 am-11:31 am
1 stop6h 31m
George Town Owen Roberts Intl
Tue 7/14
12:56 pm-11:59 pm
1 stop10h 03m
$476
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sat 8/1
7:00 am-12:30 pm
2 stops30h 30m
George Town Owen Roberts Intl
Sat 8/8
4:45 pm-11:59 pm
2 stops30h 14m
$532
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Mon 6/29
7:00 am-12:30 pm
2 stops30h 30m
George Town Owen Roberts Intl
Sat 7/4
1:35 pm-4:52 pm
2 stops26h 17m
$603
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sat 8/1
7:35 pm-11:25 am
1 stop16h 50m
George Town Owen Roberts Intl
Sat 8/8
4:15 pm-12:38 pm
2 stops19h 23m
$630
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Thu 7/2
5:12 pm-11:34 am
1 stop19h 22m
George Town Owen Roberts Intl
Mon 7/6
12:59 pm-11:59 pm
1 stop10h 00m
$680
Cheapest one-way
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sat 6/6
7:30 pm-11:30 am
1 stop17h 00m
$108
Quickest one-way
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sat 6/6
7:00 am-1:30 pm
1 stop7h 30m
$108
BuffaloGeorge Town
BUF - GCM
BUFGCM
Buffalo
Sat 6/6
7:52 pm-11:35 am
3 stops40h 43m
$297
Sorted by cheapest first
Best time to book a flight from Buffalo to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
BUF-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to the Cayman Islands
BUF-KY0
BUF-GCM
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Cayman Islands
Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated May 1, 2026.
Peruse reviews from past customers who have flown with American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Food
6.4
Overall
7.1
Comfort
7.2
Boarding
7.5
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Crew
7.9
Food
6.4
Overall
7.1
Comfort
7.2
Boarding
7.5
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to Cayman Islands
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Buffalo to Cayman Islands, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and Cayman Islands flights
Browse other Buffalo and Cayman Islands flight options. Last updated on May 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Cayman Islands regions
Consider these flights traveling to Cayman Islands regions.
Top airline flying from Buffalo to Cayman Islands
Discover the top airline that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$321 | Average$550 | FlexibilityNo cancel fee | On-time71% |