$417+ Cheap flights from Buffalo (BUF) to the Cayman Islands
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
Oct 20 — Oct 271
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Cayman Islands with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Cayman Islands
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Cheapest flights from Buffalo to Cayman IslandsExplore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:58 pm -
1 stop16h 25m
Mon 11/912:18 pm -
1 stop9h 22m
Deal found 9/18![American Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:31 am -
1 stop24h 59m
Fri 10/912:35 pm -
1 stop9h 15m
Deal found 9/17![American Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:58 pm -
2 stops22h 32m
Thu 10/294:45 pm -
2 stops30h 01m
Deal found 9/15![United Airlines logo]()
$448
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:56 pm -
2 stops17h 31m
Mon 10/512:35 pm -
1 stop9h 15m
Deal found 9/19![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:30 am -
1 stop5h 57m
Mon 10/52:10 pm -
2 stops19h 28m
Deal found 9/19![American Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:04 pm -
1 stop16h 27m
Tue 12/298:30 am -
1 stop14h 54m
Deal found 9/16![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:35 pm -
2 stops16h 25m
Tue 10/1312:35 pm -
1 stop8h 09m
Deal found 9/17![American Airlines logo]()
$536
Best flights from Buffalo to Cayman IslandsDiscover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
Discover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:00 am -
1 stop5h 58m
Tue 12/292:27 pm -
1 stop9h 28m
Deal found 9/19![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/67:09 am -
2 stops13h 06m
Fri 3/1212:40 pm -
2 stops9h 45m
Deal found 9/15![American Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:58 pm -
2 stops22h 32m
Thu 10/294:45 pm -
2 stops30h 01m
Deal found 9/17![United Airlines logo]()
$448
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:01 pm -
2 stops16h 22m
Mon 11/912:18 pm -
1 stop9h 22m
Deal found 9/18![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:30 am -
1 stop5h 57m
Mon 10/512:35 pm -
1 stop9h 15m
Deal found 9/19![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/267:00 am -
2 stops13h 15m
Mon 3/112:54 pm -
2 stops11h 05m
Deal found 9/17![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/246:00 am -
2 stops13h 59m
Sun 1/3112:54 pm -
2 stops10h 24m
Deal found 9/18![American Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:04 pm -
1 stop16h 27m
Tue 12/298:30 am -
1 stop14h 54m
Deal found 9/16![American Airlines logo]()
$467
Last-minute flights from Buffalo to Cayman IslandsDiscover last-minute flight deals from Buffalo to Cayman Islands. Data last updated September 20, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Cayman Islands. Data last updated September 20, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:56 pm -
2 stops17h 31m
Mon 10/512:35 pm -
1 stop9h 15m
Deal found 9/19![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:30 am -
1 stop5h 57m
Mon 10/52:10 pm -
2 stops19h 28m
Deal found 9/19![American Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:31 am -
1 stop24h 59m
Fri 10/912:35 pm -
1 stop9h 15m
Deal found 9/17![American Airlines logo]()
$443
This Gurufare deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:37 am -
2 stops30h 23m
Fri 10/912:35 pm -
1 stop9h 15m
Deal found 9/17![Multiple Airlines logo]()
$559
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:35 pm -
2 stops16h 25m
Tue 10/1312:35 pm -
1 stop8h 09m
Deal found 9/17![American Airlines logo]()
$536
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:53 pm -
3 stops46h 37m
Mon 10/124:45 pm -
3 stops24h 11m
Deal found 9/16![Multiple Airlines logo]()
$846
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:58 pm -
2 stops22h 32m
Thu 10/294:45 pm -
2 stops30h 01m
Deal found 9/15![United Airlines logo]()
$448
Find flight deals from Buffalo to Cayman Islands
Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated September 20, 2026.
Round-trip from | $375 (American Airlines) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 12/24
6:00 am-11:58 am
1 stop5h 58m
George Town Owen Roberts Intl
Tue 12/29
2:27 pm-11:55 pm
1 stop9h 28m
$417
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Sat 3/6
7:09 am-8:15 pm
2 stops13h 06m
George Town Owen Roberts Intl
Fri 3/12
12:40 pm-10:25 pm
2 stops9h 45m
$422
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Mon 11/2
7:01 pm-11:23 am
2 stops16h 22m
George Town Owen Roberts Intl
Mon 11/9
12:18 pm-9:40 pm
1 stop9h 22m
$422
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Tue 10/27
5:58 pm-3:30 pm
2 stops22h 32m
George Town Owen Roberts Intl
Thu 10/29
4:45 pm-11:46 pm
2 stops30h 01m
$448
Quickest round-trip
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Wed 9/30
6:30 am-11:27 am
1 stop5h 57m
George Town Owen Roberts Intl
Mon 10/5
12:35 pm-10:50 pm
1 stop9h 15m
$449
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Fri 2/26
7:00 am-8:15 pm
2 stops13h 15m
George Town Owen Roberts Intl
Mon 3/1
12:54 pm-11:59 pm
2 stops11h 05m
$449
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Sun 1/24
6:00 am-7:59 pm
2 stops13h 59m
George Town Owen Roberts Intl
Sun 1/31
12:54 pm-11:18 pm
2 stops10h 24m
$454
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 12/24
7:04 pm-11:31 am
1 stop16h 27m
George Town Owen Roberts Intl
Tue 12/29
8:30 am-11:24 pm
1 stop14h 54m
$467
Sorted by cheapest first
Best time to book a flight from Buffalo to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
BUF-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to the Cayman Islands
BUF-KY0
BUF-GCM
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Cayman Islands
Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated September 20, 2026.
Peruse reviews from past customers who have flown with American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Food
6.4
Boarding
7.4
Overall
7.0
Comfort
7.2
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Entertainment
6.8
Food
6.4
Boarding
7.4
Overall
7.0
Comfort
7.2
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Related info for your journey
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Complete your trip
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Buffalo and Cayman Islands flights
Browse other Buffalo and Cayman Islands flight options. Last updated on September 20, 2026.
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Top airline flying from Buffalo to Cayman Islands
Discover the top airline that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$325 | Average$555 | FlexibilityNo cancel fee | On-time71% |