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Cayman Islands

$347+ Cheap flights from Buffalo (BUF) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
Apr 14 — Apr 211
Tue 4/14
Tue 4/21
1 adult, Economy
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Cheap flight deals from Buffalo to Cayman Islands

Cheapest flights from Buffalo to Cayman Islands
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.

This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:09 am
BUF
-
GCM
1 stop9h 56m
United Airlines
Sat 5/24:10 pm
GCM
-
BUF
1 stop6h 45m
United Airlines
Deal found 3/11$347
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
BUF
-
GCM
1 stop6h 31m
American Airlines
Wed 5/132:10 pm
GCM
-
BUF
2 stops19h 41m
American Airlines
Deal found 3/15$352
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:34 pm
BUF
-
GCM
2 stops16h 27m
American Airlines
Tue 7/145:12 pm
GCM
-
BUF
2 stops20h 07m
American Airlines
Deal found 3/13$357
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:50 pm
BUF
-
GCM
2 stops22h 40m
United Airlines
Thu 12/105:45 pm
GCM
-
BUF
2 stops23h 02m
United Airlines
Deal found 3/11$366
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
BUF
-
GCM
1 stop7h 00m
Delta
Wed 5/131:19 pm
GCM
-
BUF
1 stop9h 40m
Delta
Deal found 3/15$367
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
BUF
-
GCM
1 stop6h 30m
American Airlines
Tue 7/145:12 pm
GCM
-
BUF
2 stops20h 07m
American Airlines
Deal found 3/11$422
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
BUF
-
GCM
2 stops11h 08m
American Airlines
Thu 7/1612:02 pm
GCM
-
BUF
2 stops21h 17m
American Airlines
Deal found 3/11$427
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
BUF
-
GCM
1 stop6h 30m
American Airlines
Mon 7/132:45 pm
GCM
-
BUF
2 stops30h 45m
American Airlines
Deal found 3/11$437
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:46 pm
BUF
-
GCM
2 stops27h 22m
American Airlines
Wed 7/155:12 pm
GCM
-
BUF
2 stops15h 20m
American Airlines
Deal found 3/11$439
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:42 pm
BUF
-
GCM
2 stops24h 26m
American Airlines
Mon 7/132:45 pm
GCM
-
BUF
2 stops30h 45m
American Airlines
Deal found 3/11$442
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
BUF
-
GCM
1 stop6h 31m
American Airlines
Wed 5/612:35 pm
GCM
-
BUF
1 stop10h 12m
American Airlines
Deal found 3/15$443
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
BUF
-
GCM
1 stop6h 30m
American Airlines
Sun 7/125:12 pm
GCM
-
BUF
2 stops29h 32m
American Airlines
Deal found 3/11$444

Find flight deals from Buffalo to Cayman Islands

Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated March 15, 2026.

Round-trip from

$347
(United Airlines)

Popular in

July

Cheapest in

January

Average price

$427
From Buffalo to Cayman Islands
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($67 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Tue 5/5

6:00 am-12:00 pm

1 stop7h 00m

George Town Owen Roberts Intl

Wed 5/13

1:19 pm-11:59 pm

1 stop9h 40m

$347

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sat 4/25

7:00 am-3:05 pm

2 stops9h 05m

George Town Owen Roberts Intl

Sat 5/2

4:10 pm-9:41 am

2 stops16h 31m

$352

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Tue 5/5

6:59 pm-1:10 pm

2 stops19h 11m

George Town Owen Roberts Intl

Wed 5/13

2:10 pm-10:51 am

2 stops19h 41m

$352

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Wed 4/29

7:28 pm-11:00 am

2 stops16h 32m

George Town Owen Roberts Intl

Wed 5/6

12:35 pm-11:47 pm

1 stop10h 12m

$357

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Wed 7/8

7:34 pm-11:01 am

2 stops16h 27m

George Town Owen Roberts Intl

Tue 7/14

5:12 pm-12:56 pm

2 stops18h 44m

$357

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sun 4/26

7:00 am-12:45 pm

1 stop6h 45m

George Town Owen Roberts Intl

Thu 4/30

1:35 pm-9:41 am

2 stops19h 06m

$462
Quickest round-trip

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sun 4/26

7:00 am-1:58 pm

1 stop7h 58m

George Town Owen Roberts Intl

Thu 4/30

2:05 pm-9:59 pm

1 stop6h 54m

$486
Cheapest one-way

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Fri 7/10

7:31 pm-12:55 pm

1 stop18h 24m

$468
Quickest one-way

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Fri 7/10

5:52 pm-9:55 am

2 stops17h 03m

$697

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/14

Sorted by cheapest first

Best time to book a flight from Buffalo to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to the Cayman Islands
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated March 15, 2026.
Peruse reviews from past customers who have flown with American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,472 reviews

Boarding

7.5

Overall

7.1

Comfort

7.2

Entertainment

6.9

Food

6.4

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,472 reviews
American Airlines
7.1
Good
11,472 reviews

Boarding

7.5

Overall

7.1

Comfort

7.2

Entertainment

6.9

Food

6.4

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Cayman Islands?

    Located just 8.3 mi from the city center, Buffalo (BUF) is the airport most travelers will use when flying to Cayman Islands from Buffalo.

  • How long is the flight from Buffalo to Cayman Islands?

    A quick flight from Buffalo to Cayman Islands can take about 9h 56m. United Airlines provides one of the quickest options available for as low as $347. The distance between Buffalo and Cayman Islands is about 1640 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Buffalo to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Buffalo to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Cayman Islands.

  • Can I find deals for business class flights from Buffalo to Cayman Islands?

    Yes. Cheapflights offers flight deals from Buffalo to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Buffalo to Cayman Islands

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Top airline flying from Buffalo to Cayman Islands

Discover the top airline that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$339Average$550FlexibilityNo cancel feeOn-time71%

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