$266+ Cheap flights from Panama City, FL (ECP) to Cancún (CUN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CUN
Oct 8 — Oct 151
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Cancún with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Cancún
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Best
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One-way
Cheapest flights from Panama City to CancúnExplore the most affordable flight options available from Panama City to Cancún. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from Panama City to Cancún. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:00 am -
1 stop8h 06m
Wed 12/22:55 pm -
1 stop9h 22m
Deal found 9/3![Delta logo]()
$550
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:15 am -
1 stop5h 50m
Fri 10/301:05 pm -
2 stops9h 10m
Deal found 9/7![Southwest logo]()
$553
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:23 am -
1 stop4h 47m
Sat 12/128:05 am -
1 stop13h 01m
Deal found 9/7![Delta logo]()
$570
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:49 pm -
2 stops16h 48m
Wed 12/212:20 pm -
2 stops11h 32m
Deal found 9/6![American Airlines logo]()
$588
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:12 pm -
1 stop15h 42m
Thu 10/2912:15 pm -
1 stop6h 27m
Deal found 9/6![American Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:05 pm -
2 stops17h 32m
Sat 12/123:36 pm -
1 stop8h 16m
Deal found 9/3![American Airlines logo]()
$605
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:41 am -
1 stop7h 38m
Sun 9/277:51 am -
1 stop14h 27m
Deal found 9/4![United Airlines logo]()
$640
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:42 pm -
2 stops17h 03m
Sun 10/257:20 am -
1 stop13h 57m
Deal found 9/3![American Airlines logo]()
$655
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:35 am -
1 stop12h 15m
Mon 9/288:05 am -
1 stop7h 26m
Deal found 9/3![Delta logo]()
$656
Best flights from Panama City to CancúnDiscover carefully curated flight deals from Panama City to Cancún that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from Panama City to Cancún that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:00 am -
1 stop8h 06m
Wed 12/26:04 am -
2 stops9h 54m
Deal found 9/3![Delta logo]()
$550
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:15 am -
1 stop5h 50m
Fri 10/301:05 pm -
2 stops9h 10m
Deal found 9/7![Southwest logo]()
$553
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:49 pm -
2 stops16h 48m
Wed 12/212:20 pm -
2 stops11h 32m
Deal found 9/6![American Airlines logo]()
$588
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:41 am -
1 stop7h 38m
Sun 9/277:51 am -
1 stop14h 27m
Deal found 9/4![United Airlines logo]()
$640
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:23 am -
1 stop4h 47m
Sat 12/128:05 am -
1 stop13h 01m
Deal found 9/7![Delta logo]()
$570
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:42 pm -
2 stops15h 25m
Thu 10/2912:45 pm -
2 stops11h 08m
Deal found 9/6![American Airlines logo]()
$605
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/58:50 am -
1 stop5h 47m
Fri 1/84:47 pm -
1 stop5h 56m
Deal found 9/7![United Airlines logo]()
$710
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:42 pm -
1 stop18h 53m
Sun 10/257:20 am -
1 stop13h 57m
Deal found 9/3![American Airlines logo]()
$659
Last-minute flights from Panama City to CancúnDiscover last-minute flight deals from Panama City to Cancún. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Cancún. Data last updated September 8, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:35 am -
1 stop12h 15m
Mon 9/288:05 am -
1 stop7h 26m
Deal found 9/3![Delta logo]()
$656
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:17 pm -
2 stops19h 16m
Mon 9/2811:33 am -
2 stops9h 34m
Deal found 9/3![American Airlines logo]()
$725
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:41 am -
1 stop7h 38m
Sun 9/277:51 am -
1 stop14h 27m
Deal found 9/4![United Airlines logo]()
$640
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:42 pm -
2 stops17h 03m
Sun 10/257:20 am -
1 stop13h 57m
Deal found 9/3![American Airlines logo]()
$655
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:12 pm -
1 stop15h 42m
Thu 10/2912:15 pm -
1 stop6h 27m
Deal found 9/6![American Airlines logo]()
$600
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:15 am -
1 stop5h 50m
Fri 10/302:20 pm -
1 stop6h 35m
Deal found 9/7![Southwest logo]()
$553
One-way flights from Panama City to CancúnSearch for one-way flight options from Panama City to Cancún. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
Search for one-way flight options from Panama City to Cancún. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:04 am -
1 stop7h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$266
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:04 pm -
2 stops17h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$324
Find flight deals from Panama City to Cancún
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Cancún (CUN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $550 (Delta) |
One-way from | $266 (Delta) |
Popular in | June |
Cheapest in | December |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Cancún that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from Panama City to Cancún that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityCancún
ECP Panama City NW Florida Beaches - CUN Cancun
ECPCUN
Panama City NW Florida Beaches
Sat 12/5
7:04 am-3:10 pm
1 stop7h 06m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$266
Panama CityCancún
ECP Panama City NW Florida Beaches - CUN Cancun
ECPCUN
Panama City NW Florida Beaches
Tue 12/29
6:23 am-5:50 pm
1 stop10h 27m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$310
Panama CityCancún
ECP Panama City NW Florida Beaches - CUN Cancun
ECPCUN
Panama City NW Florida Beaches
Mon 12/28
7:35 am-7:45 pm
2 stops11h 10m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$321
Panama CityCancún
ECP Panama City NW Florida Beaches - CUN Cancun
ECPCUN
Panama City NW Florida Beaches
Sat 12/5
4:04 pm-10:36 am
2 stops17h 32m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$324
Panama CityCancún
ECP Panama City NW Florida Beaches - CUN Cancun
ECPCUN
Panama City NW Florida Beaches
Mon 12/28
6:23 am-5:50 pm
1 stop10h 27m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$324
Panama CityCancún
ECP Panama City NW Florida Beaches - CUN Cancun
ECPCUN
Panama City NW Florida Beaches
Sun 11/29
6:00 am-3:06 pm
1 stop8h 06m
Cancun
Wed 12/2
6:04 am-2:58 pm
2 stops9h 54m
$550
Panama CityCancún
ECP Panama City NW Florida Beaches - CUN Cancun
ECPCUN
Panama City NW Florida Beaches
Fri 10/23
7:15 am-1:05 pm
1 stop5h 50m
Cancun
Fri 10/30
1:05 pm-10:15 pm
2 stops9h 10m
$553
Panama CityCancún
ECP Panama City NW Florida Beaches - CUN Cancun
ECPCUN
Panama City NW Florida Beaches
Sat 12/5
9:23 am-3:10 pm
1 stop4h 47m
Cancun
Sat 12/12
8:05 am-8:06 pm
1 stop13h 01m
$570
Panama CityCancún
ECP Panama City NW Florida Beaches - CUN Cancun
ECPCUN
Panama City NW Florida Beaches
Sun 11/29
6:49 pm-12:37 pm
2 stops16h 48m
Cancun
Wed 12/2
12:20 pm-10:52 pm
2 stops11h 32m
$588
Panama CityCancún
ECP Panama City NW Florida Beaches - CUN Cancun
ECPCUN
Panama City NW Florida Beaches
Thu 10/22
6:42 pm-10:07 am
2 stops15h 25m
Cancun
Thu 10/29
12:45 pm-11:53 pm
2 stops11h 08m
$605
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Panama City to Cancún
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Cancún in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Cancún flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Cancún flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Cancún flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Cancún flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Cancún flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Cancún
Have a flexible travel schedule? Discover the best time to fly to Cancún from Panama City with our price prediction graph.
ECP-CUN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Cancún
Get insights into the airlines that provide service to Cancún. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cancún. Reviews last updated September 8, 2026.
Read through reviews of airlines operating flights from Panama City to Cancún, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Comfort
7.8
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Comfort
7.8
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Comfort
7.8
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Cancún. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Cancún?
Book flights to Cancún if you plan to visit one of these locationsPuerto Aventuras
Punta Sam
Holbox
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Other flights to Cancún
Explore flights to Cancún departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 8, 2026.
Complete your trip
Complete your trip to Cancún by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Panama City to Cancún, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Cancún flights
Browse other Panama City and Cancún flight options. Last updated on September 8, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama City to Cancún
Discover the top 2 airlines that operate flights from Panama City to Cancún. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$379 | Average$605 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$428 | Average$521 | FlexibilityNo cancel fee | On-time69% |