Cabo San Lucas

$172+ Cheap flights from Missouri to Cabo San Lucas, Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SJD
Apr 17 — Apr 241
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Cheap flight deals from Missouri to Cabo San Lucas

Cheapest flights from Missouri to Cabo San Lucas
Explore the most affordable flight options available from Missouri to Cabo San Lucas. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 18, 2026.

This lastminute.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:25 am
STL
-
SJD
2 stops12h 24m
Aeromexico
Wed 5/610:24 am
SJD
-
STL
2 stops11h 12m
Aeromexico
Deal found 3/15$356
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
MCI
-
SJD
2 stops13h 49m
Delta
Tue 4/2812:34 pm
SJD
-
MCI
1 stop8h 27m
Delta
Deal found 3/16$388
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:15 am
MCI
-
SJD
1 stop8h 33m
United Airlines
Fri 5/81:44 pm
SJD
-
MCI
2 stops16h 57m
United Airlines
Deal found 3/16$393
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:59 am
STL
-
SJD
2 stops14h 19m
Delta
Tue 5/121:09 pm
SJD
-
STL
1 stop9h 21m
Delta
Deal found 3/12$396
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:20 am
STL
-
SJD
1 stop6h 25m
American Airlines
Tue 5/122:59 pm
SJD
-
STL
1 stop15h 55m
American Airlines
Deal found 3/12$401
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
MCI
-
SJD
1 stop9h 43m
United Airlines
Fri 4/101:44 pm
SJD
-
MCI
1 stop17h 45m
United Airlines
Deal found 3/16$415
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:20 am
STL
-
SJD
2 stops13h 28m
Delta
Tue 5/126:07 am
SJD
-
STL
2 stops13h 22m
Delta
Deal found 3/17$416
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
MCI
-
SJD
2 stops8h 48m
United Airlines
Tue 4/281:44 pm
SJD
-
MCI
2 stops17h 08m
United Airlines
Deal found 3/14$429
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:06 am
MCI
-
SJD
1 stop7h 49m
Delta
Mon 4/202:55 pm
SJD
-
MCI
1 stop7h 43m
Delta
Deal found 3/13$433
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:20 am
STL
-
SJD
1 stop6h 15m
American Airlines
Fri 5/82:59 pm
SJD
-
STL
1 stop6h 00m
American Airlines
Deal found 3/17$435
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
STL
-
SJD
1 stop7h 31m
Delta
Wed 5/66:07 am
SJD
-
STL
2 stops13h 12m
Delta
Deal found 3/12$441
This Trip.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:41 pm
STL
-
SJD
2 stops18h 51m
Aeromexico
Fri 5/86:07 am
SJD
-
STL
2 stops15h 52m
Aeromexico
Deal found 3/17$445

Find flight deals from Missouri to Cabo San Lucas

Keep the following information in mind while searching for Missouri to Cabo San Lucas flight deals. Data was last updated March 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$356
(lastminute.com)

One-way from

$172
(United Airlines)

Popular in

December

Cheapest in

July

Average price

$680
Provider with most accurate pricing for Lambert-St Louis-San José del Cabo Los Cabos flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-San José del Cabo Los Cabos flights.
From Missouri to Cabo San Lucas
One-way flight from Missouri to Cabo San Lucas
Highest demand for flights based on searches. 4% potential increase in price ($29 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Cabo San Lucas that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Missouri to Cabo San Lucas that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSan José del Cabo

STL - SJD

STLSJD

Lambert-St Louis

Wed 4/29

6:00 am-1:04 pm

1 stop9h 04m

San José del Cabo Los Cabos

Wed 5/6

10:24 am-11:35 pm

2 stops11h 11m

$396

St. LouisSan José del Cabo

STL - SJD

STLSJD

Lambert-St Louis

Wed 4/29

6:00 am-10:30 am

1 stop6h 30m

San José del Cabo Los Cabos

Wed 5/6

1:44 pm-10:30 pm

1 stop6h 46m

$396

St. LouisSan José del Cabo

STL - SJD

STLSJD

Lambert-St Louis

Tue 5/5

6:00 am-11:31 am

1 stop7h 31m

San José del Cabo Los Cabos

Wed 5/13

10:24 am-11:59 pm

2 stops11h 35m

$416

St. LouisSan José del Cabo

STL - SJD

STLSJD

Lambert-St Louis

Wed 5/6

11:42 am-10:18 pm

2 stops12h 36m

San José del Cabo Los Cabos

Tue 5/12

6:07 am-11:59 pm

2 stops15h 52m

$416

Kansas CitySan José del Cabo

MCI - SJD

MCISJD

Kansas City

Tue 5/5

7:00 am-1:04 pm

1 stop8h 04m

San José del Cabo Los Cabos

Sat 5/9

6:07 am-11:16 pm

2 stops15h 09m

$433

St. LouisSan José del Cabo

STL - SJD

STLSJD

Lambert-St Louis

Fri 5/1

8:30 pm-10:30 am

2 stops16h 00m

San José del Cabo Los Cabos

Fri 5/8

1:02 pm-5:47 am

1 stop14h 45m

$441

St. LouisSan José del Cabo

STL - SJD

STLSJD

Lambert-St Louis

Fri 5/1

6:00 am-11:31 am

1 stop7h 31m

San José del Cabo Los Cabos

Wed 5/6

6:07 am-9:19 pm

2 stops13h 12m

$441

ColumbiaSan José del Cabo

COU - SJD

COUSJD

Columbia Regional

Fri 5/15

7:43 pm-9:35 am

1 stop15h 52m

San José del Cabo Los Cabos

Tue 5/19

11:32 am-9:29 pm

1 stop7h 57m

$471

Kansas CitySan José del Cabo

MCI - SJD

MCISJD

Kansas City

Mon 4/27

9:00 am-1:43 pm

1 stop6h 43m

San José del Cabo Los Cabos

Thu 4/30

2:50 pm-11:59 pm

1 stop7h 09m

$498

St. LouisSan José del Cabo

STL - SJD

STLSJD

Lambert-St Louis

Sun 4/12

6:00 am-10:30 am

1 stop6h 30m

San José del Cabo Los Cabos

Wed 4/15

11:52 am-11:11 pm

1 stop9h 19m

$506

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/15

Showing 1-10 of 34 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Cabo San Lucas

Have a flexible travel schedule? Discover the best time to fly to Cabo San Lucas from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Cabo San Lucas

What is the cheapest month to book a flight from Missouri to Cabo San Lucas?

Currently, September is the cheapest month in which you can book a flight from Missouri to Cabo San Lucas (average of $193). Flying from Missouri to Cabo San Lucas in March is currently the most expensive (average of $458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to C4B?

Find hourly flight availability from Missouri to Cabo San Lucas. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 18, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Cabo San Lucas as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Cabo San Lucas. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Missouri to Cabo San Lucas?

    For as low as $393, Delta can have you in Cabo San Lucas from Missouri in 8h 33m. The distance from Missouri to Cabo San Lucas is about 1420 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Missouri to Cabo San Lucas?

  • Can I find deals for flights from Missouri to Cabo San Lucas that include hotel bookings?

    Yes. In addition to deals on Missouri to Cabo San Lucas flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Cabo San Lucas?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Cabo San Lucas.

  • Can I find deals for business class flights from Missouri to Cabo San Lucas?

    Yes. Cheapflights offers flight deals from Missouri to Cabo San Lucas by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Cabo San Lucas?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Cabo San Lucas (average of $193). Flying from Missouri to Cabo San Lucas in March is currently the most expensive (average of $458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Missouri to Cabo San Lucas

Discover the top 4 airlines that operate flights from Missouri to Cabo San Lucas. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$174Average$559FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$365Average$606FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$396Average$591FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$419Average$623FlexibilityNo cancel feeOn-time63%

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