$186+ Cheap flights from Santa Ana, CA to Buffalo (SNA - BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — BUF
Oct 15 — Oct 221
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Santa Ana to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santa Ana to BuffaloExplore the most affordable flight options available from Santa Ana to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Santa Ana to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:22 pm -
1 stop8h 37m
Mon 10/196:15 am -
1 stop7h 07m
Deal found 9/10![Delta logo]()
$397
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:22 pm -
1 stop8h 37m
Mon 10/196:15 am -
1 stop7h 07m
Deal found 9/10![Delta logo]()
$423
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:32 am -
1 stop9h 27m
Mon 10/196:15 am -
1 stop7h 07m
Deal found 9/10![Delta logo]()
$458
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:47 am -
1 stop6h 49m
Sat 10/3110:51 am -
1 stop9h 34m
Deal found 9/14![United Airlines logo]()
$481
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:22 pm -
1 stop8h 37m
Sun 10/186:15 am -
1 stop7h 07m
Deal found 9/14![Delta logo]()
$489
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:22 pm -
1 stop8h 37m
Tue 10/136:15 am -
1 stop7h 07m
Deal found 9/14![Delta logo]()
$493
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:31 pm -
2 stops12h 22m
Mon 10/193:35 pm -
1 stop7h 41m
Deal found 9/14![American Airlines logo]()
$497
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:31 pm -
2 stops12h 17m
Sun 10/187:00 am -
1 stop8h 36m
Deal found 9/14![American Airlines logo]()
$499
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:01 pm -
1 stop7h 53m
Wed 10/214:48 pm -
1 stop8h 41m
Deal found 9/10![American Airlines logo]()
$507
Best flights from Santa Ana to BuffaloDiscover carefully curated flight deals from Santa Ana to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Santa Ana to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:47 am -
1 stop6h 49m
Sat 10/3110:51 am -
1 stop9h 34m
Deal found 9/14![United Airlines logo]()
$481
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:22 pm -
1 stop8h 37m
Sun 10/186:15 am -
1 stop7h 07m
Deal found 9/14![Delta logo]()
$489
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:31 pm -
2 stops12h 22m
Mon 10/193:35 pm -
1 stop7h 41m
Deal found 9/14![American Airlines logo]()
$497
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:35 pm -
2 stops9h 50m
Wed 10/213:25 pm -
1 stop9h 00m
Deal found 9/12![Southwest logo]()
$590
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:46 am -
2 stops8h 50m
Sat 11/78:50 am -
1 stop7h 24m
Deal found 9/11![United Airlines logo]()
$524
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:45 am -
1 stop9h 08m
Sun 11/154:40 pm -
1 stop8h 54m
Deal found 9/13![American Airlines logo]()
$587
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:50 am -
1 stop8h 25m
Sun 11/154:00 pm -
2 stops9h 20m
Deal found 9/13![Southwest logo]()
$592
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:32 am -
1 stop9h 27m
Wed 10/146:15 am -
1 stop7h 07m
Deal found 9/12![Delta logo]()
$619
Last-minute flights from Santa Ana to BuffaloDiscover last-minute flight deals from Santa Ana to Buffalo. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Buffalo. Data last updated September 15, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:32 am -
1 stop9h 27m
Mon 10/196:15 am -
1 stop7h 07m
Deal found 9/10![Delta logo]()
$458
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:01 pm -
1 stop7h 53m
Wed 10/214:48 pm -
1 stop8h 41m
Deal found 9/10![American Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:22 pm -
1 stop8h 37m
Tue 10/136:15 am -
1 stop7h 07m
Deal found 9/14![Delta logo]()
$493
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:22 pm -
1 stop8h 37m
Mon 10/196:15 am -
1 stop7h 07m
Deal found 9/10![Delta logo]()
$423
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:31 pm -
2 stops12h 22m
Mon 10/193:35 pm -
1 stop7h 41m
Deal found 9/14![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:22 pm -
1 stop8h 37m
Mon 10/196:15 am -
1 stop7h 07m
Deal found 9/10![Delta logo]()
$397
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:22 pm -
1 stop8h 37m
Sun 10/186:15 am -
1 stop7h 07m
Deal found 9/14![Delta logo]()
$489
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:31 pm -
2 stops12h 17m
Sun 10/187:00 am -
1 stop8h 36m
Deal found 9/14![American Airlines logo]()
$499
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:47 am -
1 stop6h 49m
Sat 10/3110:51 am -
1 stop9h 34m
Deal found 9/14![United Airlines logo]()
$481
One-way flights from Santa Ana to BuffaloSearch for one-way flight options from Santa Ana to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Santa Ana to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:22 pm -
1 stop8h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$186
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:31 pm -
2 stops12h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$191
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:22 pm -
1 stop8h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:59 pm -
2 stops38h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Frontier logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:30 am -
2 stops31h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$217
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:35 pm -
1 stop7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Southwest logo]()
$225
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:08 pm -
2 stops17h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$227
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:42 am -
2 stops10h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![American Airlines logo]()
$230
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:35 pm -
2 stops17h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$232
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:15 pm -
1 stop10h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$239
Find flight deals from Santa Ana to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $397 (Delta) |
One-way from | $186 (Delta) |
Popular in | April |
Cheapest in | January |
Average price | $566 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Santa Ana to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaBuffalo
SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo
SNABUF
Santa Ana J. Wayne/Orange Cnty
Wed 10/7
12:22 pm-11:59 pm
1 stop8h 37m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$186
Santa AnaBuffalo
SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo
SNABUF
Santa Ana J. Wayne/Orange Cnty
Wed 10/7
1:35 pm-12:30 am
1 stop7h 55m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$225
Santa AnaBuffalo
SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo
SNABUF
Santa Ana J. Wayne/Orange Cnty
Fri 10/23
12:22 pm-11:59 pm
1 stop8h 37m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$239
Santa AnaBuffalo
SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo
SNABUF
Santa Ana J. Wayne/Orange Cnty
Wed 10/14
11:35 am-11:59 pm
1 stop9h 24m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$260
Santa AnaBuffalo
SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo
SNABUF
Santa Ana J. Wayne/Orange Cnty
Thu 10/15
12:30 pm-12:20 am
1 stop8h 50m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$294
Quickest round-trip
Santa AnaBuffalo
SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo
SNABUF
Santa Ana J. Wayne/Orange Cnty
Fri 10/2
10:37 am-8:47 pm
1 stop7h 10m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$315
Santa AnaBuffalo
SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo
SNABUF
Santa Ana J. Wayne/Orange Cnty
Fri 10/2
10:01 am-11:40 pm
2 stops10h 39m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$340
Santa AnaBuffalo
SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo
SNABUF
Santa Ana J. Wayne/Orange Cnty
Wed 10/7
7:30 am-5:52 pm
3 stops31h 22m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$342
Santa AnaBuffalo
SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo
SNABUF
Santa Ana J. Wayne/Orange Cnty
Sat 10/10
10:37 am-8:47 pm
1 stop7h 10m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$370
Santa AnaBuffalo
SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo
SNABUF
Santa Ana J. Wayne/Orange Cnty
Fri 9/25
11:29 am-10:43 pm
1 stop8h 14m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$380
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Buffalo in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santa Ana with our price prediction graph.
SNA-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to Buffalo
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated September 15, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from Santa Ana to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Buffalo flight routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Santa Ana
Popular flights
Alternative routes for Santa Ana to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Santa Ana to Buffalo by cabin class
Find flights from Santa Ana to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Santa Ana and Buffalo flights
Browse other Santa Ana and Buffalo flight options. Last updated on September 15, 2026.
Other flights from Santa Ana
Browse through other flights departing from Santa Ana. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Santa Ana to Buffalo
Discover the top 3 airlines that operate flights from Santa Ana to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$350 | Average$646 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$370 | Average$563 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$462 | Average$622 | FlexibilityNo cancel fee | On-time63% |