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$535+ Cheap flights from Panama City (PTY) to Buffalo (BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/23. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — BUF
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Panama City to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$535
(United Airlines)

Popular in

October

Cheapest in

June

Average price

$294
From Panama City Tocumen Intl to Buffalo
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($172 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 17% potential price decrease ($90 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
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Find flight deals from Panama City to Buffalo

Cheapest flights from Panama City to Buffalo
Explore the most affordable flight options available from Panama City to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/233:30 pmPTY - BUF
2 stops17h 24mUnited Airlines
Mon 7/287:45 pmBUF - PTY
2 stops21h 27mUnited Airlines
Deal found 6/12$535
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/251:55 pmPTY - BUF
2 stops19h 42mAmerican Airlines
Fri 8/17:37 pmBUF - PTY
2 stops18h 17mAmerican Airlines
Deal found 6/9$548
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/252:28 pmPTY - BUF
1 stop8h 31mDelta
Fri 8/112:07 pmBUF - PTY
1 stop8h 24mDelta
Deal found 6/9$585
This Mytrip deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/251:30 pmPTY - BUF
3 stops44h 14mMultiple Airlines
Fri 8/111:35 amBUF - PTY
3 stops32h 40mMultiple Airlines
Deal found 6/9$829
This Expedia deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/253:40 pmPTY - BUF
2 stops29h 48mAvianca
Fri 8/110:30 amBUF - PTY
3 stops29h 15mAvianca
Deal found 6/9$1,658

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Panama City to Buffalo that are best for you.

Fly from

Panama City

Fly to

Buffalo

Route

Depart

Return

Price

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Wed 7/23

3:30 pm-9:54 am

2 stops17h 24m

Buffalo

Mon 7/28

7:45 pm-4:12 pm

2 stops21h 27m

$535

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 7/25

1:55 pm-10:37 am

2 stops19h 42m

Buffalo

Fri 8/1

7:37 pm-12:54 pm

2 stops18h 17m

$548

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 7/25

2:28 pm-11:59 pm

1 stop8h 31m

Buffalo

Fri 8/1

12:07 pm-7:31 pm

1 stop8h 24m

$585

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 7/25

1:30 pm-10:44 am

3 stops44h 14m

Buffalo

Fri 8/1

11:35 am-7:15 pm

3 stops32h 40m

$829

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 7/25

3:40 pm-10:28 pm

2 stops29h 48m

Buffalo

Fri 8/1

10:30 am-2:45 pm

3 stops29h 15m

$1,658

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from Panama City to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Buffalo

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,946 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Avianca
6.7
Okay
2,345 reviews
Delta
8.0
Very good
7,946 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Panama City to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to Buffalo round-trip?

    Currently priced at $535, United Airlines will fly you from Panama City to Buffalo and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Delta - these airlines can fly you to your destination from $548 and $585, respectively. Users have found that United Airlines is 11% cheaper than the other options available to this destination.

  • Can I find deals for flights from Panama City to Buffalo that include hotel bookings?

    Yes. In addition to deals on Panama City to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Buffalo.

  • Can I find deals for business class flights from Panama City to Buffalo?

    Yes. Cheapflights offers flight deals from Panama City to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Buffalo (average of $256). Flying from Panama City to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Williamsville
Amherst
Orchard Park
Batavia
Eden
Cheektowaga
West Seneca

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Alternative routes for Panama City to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
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