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$145+ Cheap flights from Myrtle Beach to Buffalo (MYR - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/23. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — BUF
jul. 8 — jul. 151
mar. 7/8
mar. 7/15
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 3, 2025.

Round-trip from

$243
(Delta)

One-way from

$145
(American Airlines)

Popular in

February

Cheapest in

September

Average price

$324
From Myrtle Beach Intl to Buffalo
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One-way flight from Myrtle Beach Intl to Buffalo
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Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Myrtle Beach to Buffalo

Cheapest flights from Myrtle Beach to Buffalo
Explore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/166:00 amMYR - BUF
1 stop4h 57mDelta
lun. 8/187:15 pmBUF - MYR
1 stop4h 34mDelta
Deal found 7/1$243
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/312:37 pmMYR - BUF
1 stop6h 10mAmerican Airlines
dom. 11/212:03 pmBUF - MYR
1 stop6h 53mAmerican Airlines
Deal found 7/3$244
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/145:12 pmMYR - BUF
1 stop6h 26mUnited Airlines
dom. 8/177:00 amBUF - MYR
1 stop7h 35mUnited Airlines
Deal found 7/1$248
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/166:10 amMYR - BUF
1 stop9h 05mSouthwest
mar. 8/191:20 pmBUF - MYR
1 stop6h 25mSouthwest
Deal found 7/1$287
This Frontier deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/173:50 pmMYR - BUF
2 stops15h 57mFrontier
lun. 7/218:50 amBUF - MYR
2 stops11h 38mFrontier
Deal found 7/2$433

Cheapflights Fare Finder

Customize your flight search to find flights from Myrtle Beach to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Buffalo that are best for you.

Fly from

Myrtle Beach

Fly to

Buffalo

Route

Depart

Return

Price

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

sáb. 8/16

6:00 am-10:57 am

1 stop4h 57m

Buffalo

lun. 8/18

7:15 pm-11:49 pm

1 stop4h 34m

$243

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

jue. 8/21

11:51 am-6:34 pm

1 stop6h 43m

Buffalo

dom. 8/24

6:15 am-9:55 am

1 stop3h 40m

$247

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

jue. 8/14

5:12 pm-11:38 pm

1 stop6h 26m

Buffalo

dom. 8/17

7:00 am-2:35 pm

1 stop7h 35m

$248

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

sáb. 8/16

6:10 am-3:15 pm

1 stop9h 05m

Buffalo

mar. 8/19

1:20 pm-7:45 pm

1 stop6h 25m

$287

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

jue. 7/17

3:50 pm-7:47 am

2 stops15h 57m

Buffalo

lun. 7/21

8:50 am-8:28 pm

2 stops11h 38m

$433

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

mié. 7/23

6:16 pm-12:32 am

1 stop6h 16m

$145

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

vie. 7/25

2:47 pm-11:38 pm

2 stops8h 51m

$199

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

mié. 7/23

8:58 pm-10:44 am

3 stops37h 46m

$265

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Myrtle Beach to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Buffalo

What is the cheapest month to book a flight from Myrtle Beach to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Buffalo (average of $256). Flying from Myrtle Beach to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to BUF?

Find hourly flight availability from Myrtle Beach to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 3, 2025.

It’s typically best to fly out from Myrtle Beach to Buffalo in the afternoon. Doing so could potentially save you 11% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated julio 3, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Myrtle Beach to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,266 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,266 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,982 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,861 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Frontier
5.9
Fair
3,286 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Myrtle Beach to Buffalo round-trip?

    According to our current data, Delta ($243), American Airlines ($247), and United Airlines ($248) offers the cheapest pricing from Myrtle Beach to Buffalo. Delta is priced at 33% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Myrtle Beach to Buffalo that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Buffalo.

  • Can I find deals for business class flights from Myrtle Beach to Buffalo?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Buffalo (average of $256). Flying from Myrtle Beach to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Williamsville
Orchard Park
Batavia
Eden
Amherst
West Seneca

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Alternative routes for Myrtle Beach to Buffalo

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Top 2 airlines flying from Myrtle Beach to Buffalo

Discover the top 2 airlines that operate flights from Myrtle Beach to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$243Average$331FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$276Average$406FlexibilityNo cancel feeOn-time63%

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