$268+ Cheap flights from Key West to Buffalo (EYW - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BUF
Feb 28 — Mar 71
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to Buffalo
Cheapest flights from Key West to BuffaloExplore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
Explore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:04 pm
EYW
- BUF
1 stop5h 45m
American Airlines
Tue 2/175:24 am
BUF
- EYW
1 stop6h 02m
American Airlines
Deal found 1/28![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:40 pm
EYW
- BUF
1 stop7h 10m
American Airlines
Mon 3/305:30 am
BUF
- EYW
1 stop8h 15m
American Airlines
Deal found 1/28![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:35 pm
EYW
- BUF
1 stop5h 09m
United Airlines
Sun 3/16:07 am
BUF
- EYW
1 stop10h 00m
United Airlines
Deal found 1/28![United Airlines logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:51 am
EYW
- BUF
2 stops24h 14m
Multiple Airlines
Sun 3/299:25 pm
BUF
- EYW
1 stop15h 01m
Multiple Airlines
Deal found 1/28![Multiple Airlines logo]()
$438
Find flight deals from Key West to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $339 (American Airlines) |
One-way from | $268 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Key West to Buffalo that are best for you.
Fly from
Key West
Fly to
Buffalo
Route
Depart
Return
Price
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Fri 2/13
5:04 pm-10:49 pm
1 stop5h 45m
Buffalo
Tue 2/17
5:24 am-11:26 am
1 stop6h 02m
$339
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 3/18
4:40 pm-11:50 pm
1 stop7h 10m
Buffalo
Mon 3/30
5:30 am-1:45 pm
1 stop8h 15m
$364
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 2/26
6:35 pm-11:44 pm
1 stop5h 09m
Buffalo
Sun 3/1
6:07 am-1:15 pm
2 stops31h 08m
$388
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 3/18
11:51 am-12:05 pm
2 stops24h 14m
Buffalo
Sun 3/29
9:25 pm-12:26 pm
1 stop15h 01m
$438
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 5/4
2:25 pm-12:13 pm
2 stops21h 48m
$268
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Fri 4/10
2:35 pm-12:14 pm
2 stops21h 39m
$270
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 5/4
8:05 am-1:04 pm
1 stop4h 59m
$305
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 5/27
1:02 pm-6:38 pm
1 stop5h 36m
$306
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 5/27
2:35 pm-11:03 pm
2 stops8h 28m
$355
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Fri 4/3
12:55 pm-6:45 pm
1 stop5h 50m
$360
Showing 1-10 of 12 results
- Most accurate provider: When it comes to deals on Key West-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Key West to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Related info for your journey
Find useful and relevant information for your journey from Key West to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
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Alternative routes for Key West to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Key West to Buffalo
Discover the top 2 airlines that operate flights from Key West to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$259 | Average$318 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$415 | FlexibilityNo cancel fee | On-time71% |