$90+ Cheap flights from Key West to Buffalo (EYW - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BUF
Jan 3 — Jan 101
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Key West to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to Buffalo
Cheapest flights from Key West to BuffaloExplore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.
Explore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:13 amEYW - BUF
1 stop5h 39mAmerican Airlines
Mon 12/226:00 amBUF - EYW
1 stop8h 14mAmerican Airlines
Deal found 12/3![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:40 amEYW - BUF
2 stops9h 30mDelta
Mon 12/2212:01 pmBUF - EYW
2 stops9h 33mDelta
Deal found 12/3![Delta logo]()
$429
Find flight deals from Key West to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 1 star |
Round-trip from | $339 (American Airlines) |
One-way from | $90 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Key West to Buffalo that are best for you.
Fly from
Key West
Fly to
Buffalo
Route
Depart
Return
Price
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 12/18
11:13 am-4:52 pm
1 stop5h 39m
Buffalo
Mon 12/22
6:00 am-2:14 pm
1 stop8h 14m
$339
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 1/22
2:25 pm-10:31 pm
1 stop8h 06m
Buffalo
Sun 1/25
8:30 am-3:17 pm
1 stop6h 47m
$359
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 12/18
7:40 am-5:10 pm
2 stops9h 30m
Buffalo
Mon 12/22
12:01 pm-9:34 pm
2 stops9h 33m
$429
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Sat 2/14
4:34 pm-1:17 pm
2 stops20h 43m
Buffalo
Wed 2/18
6:00 am-1:15 pm
1 stop7h 15m
$515
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 1/8
10:06 am-8:13 am
1 stop22h 07m
$90
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 3/16
1:06 pm-8:33 pm
1 stop7h 27m
$146
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 3/12
9:46 am-10:42 am
1 stop24h 56m
$160
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 3/16
1:38 pm-10:25 pm
2 stops8h 47m
$325
- Most accurate provider: When it comes to deals on Key West-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated December 4, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Key West to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.9
Comfort
7.9
Food
7.3
Entertainment
7.9
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Crew
8.5
Overall
7.9
Comfort
7.9
Food
7.3
Entertainment
7.9
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Crew
8.5
Overall
7.9
Comfort
7.9
Food
7.3
Entertainment
7.9
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Related info for your journey
Find useful and relevant information for your journey from Key West to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Key West to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Key West to Buffalo
Discover the top 2 airlines that operate flights from Key West to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$259 | Average$318 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$408 | FlexibilityNo cancel fee | On-time71% |