$128+ Cheap flights from Key West to Buffalo (EYW - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BUF
Apr 12 — Apr 191
Round-trip
1 adult, Economy
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Find cheap flights from Key West to Buffalo with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to Buffalo
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Best
Last-minute
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Cheapest flights from Key West to BuffaloExplore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
Explore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:22 pm
EYW
- BUF
1 stop26h 24m
Multiple Airlines
Mon 3/307:41 pm
BUF
- EYW
1 stop16h 40m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$296
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:23 pm
EYW
- BUF
1 stop5h 14m
Delta
Sun 5/36:00 am
BUF
- EYW
1 stop6h 40m
Delta
Deal found 3/9![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:03 pm
EYW
- BUF
1 stop6h 56m
American Airlines
Sun 5/31:45 pm
BUF
- EYW
2 stops9h 13m
American Airlines
Deal found 3/9![American Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:06 pm
EYW
- BUF
1 stop21h 43m
Multiple Airlines
Sun 5/38:08 pm
BUF
- EYW
2 stops13h 01m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/262:24 pm
EYW
- BUF
2 stops9h 18m
United Airlines
Mon 3/306:09 am
BUF
- EYW
2 stops11h 30m
United Airlines
Deal found 3/11![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:26 pm
EYW
- BUF
1 stop8h 05m
United Airlines
Tue 6/27:00 am
BUF
- EYW
1 stop8h 07m
United Airlines
Deal found 3/10![United Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:40 pm
EYW
- BUF
1 stop5h 56m
American Airlines
Sat 7/111:46 pm
BUF
- EYW
1 stop5h 01m
American Airlines
Deal found 3/8![American Airlines logo]()
$439
Best flights from Key West to BuffaloDiscover carefully curated flight deals from Key West to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
Discover carefully curated flight deals from Key West to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:58 pm
EYW
- BUF
2 stops7h 49m
American Airlines
Sun 5/31:45 pm
BUF
- EYW
2 stops9h 13m
American Airlines
Deal found 3/9![American Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:06 pm
EYW
- BUF
1 stop21h 43m
Multiple Airlines
Sun 5/38:08 pm
BUF
- EYW
2 stops13h 01m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/262:24 pm
EYW
- BUF
2 stops9h 18m
United Airlines
Mon 3/306:09 am
BUF
- EYW
2 stops11h 30m
United Airlines
Deal found 3/11![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:26 pm
EYW
- BUF
1 stop8h 05m
United Airlines
Tue 6/27:00 am
BUF
- EYW
1 stop8h 07m
United Airlines
Deal found 3/10![United Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:40 pm
EYW
- BUF
2 stops7h 19m
American Airlines
Sat 7/111:46 pm
BUF
- EYW
1 stop5h 01m
American Airlines
Deal found 3/8![American Airlines logo]()
$444
Last-minute flights from Key West to BuffaloDiscover last-minute flight deals from Key West to Buffalo. Data last updated March 13, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to Buffalo. Data last updated March 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:22 pm
EYW
- BUF
1 stop26h 24m
Multiple Airlines
Mon 3/307:41 pm
BUF
- EYW
1 stop16h 40m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$296
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/262:24 pm
EYW
- BUF
2 stops9h 18m
United Airlines
Mon 3/306:09 am
BUF
- EYW
2 stops11h 30m
United Airlines
Deal found 3/11![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/275:30 pm
EYW
- BUF
1 stop6h 26m
United Airlines
Tue 3/317:00 am
BUF
- EYW
1 stop7h 51m
United Airlines
Deal found 3/12![United Airlines logo]()
$459
One-way flights from Key West to BuffaloSearch for one-way flight options from Key West to Buffalo. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
Search for one-way flight options from Key West to Buffalo. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/61:06 pm
EYW
- BUF
2 stops46h 27m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:46 am
EYW
- BUF
2 stops23h 14m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/132:35 pm
EYW
- BUF
2 stops46h 17m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$206
Find flight deals from Key West to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $296 (Kiwi.com) |
One-way from | $128 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Key West to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Fri 5/1
3:58 pm-11:47 pm
2 stops7h 49m
Buffalo
Sun 5/3
1:45 pm-10:58 pm
2 stops9h 13m
$319
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Fri 5/1
1:06 pm-10:49 am
1 stop21h 43m
Buffalo
Sun 5/3
8:08 pm-9:09 am
2 stops13h 01m
$326
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 3/26
2:24 pm-11:42 pm
2 stops9h 18m
Buffalo
Mon 3/30
6:09 am-5:39 pm
2 stops11h 30m
$389
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Fri 5/29
2:26 pm-10:31 pm
1 stop8h 05m
Buffalo
Tue 6/2
7:00 am-3:07 pm
1 stop8h 07m
$431
Quickest round-trip
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 7/8
4:40 pm-11:59 pm
2 stops7h 19m
Buffalo
Sat 7/11
1:46 pm-6:47 pm
1 stop5h 01m
$444
Cheapest one-way
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 5/27
11:46 am-11:00 am
2 stops23h 14m
$146
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 4/13
2:35 pm-12:42 pm
3 stops22h 07m
$252
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Sun 3/22
12:50 pm-7:03 pm
1 stop6h 13m
$257
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 4/6
1:06 pm-7:31 pm
1 stop6h 25m
$306
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Sat 4/25
6:18 pm-11:37 pm
1 stop5h 19m
$314
Showing 1-10 of 13 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Key West-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Key West with our price prediction graph.
EYW-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Key West to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
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