$139+ Cheap flights from Key West to Buffalo (EYW - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BUF
May 10 — May 171
Round-trip
1 adult, Economy
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Find cheap flights from Key West to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Key West to BuffaloExplore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:51 am
EYW
- BUF
2 stops22h 43m
Multiple Airlines
Sun 4/263:58 pm
BUF
- EYW
1 stop20h 28m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:42 pm
EYW
- BUF
1 stop5h 37m
American Airlines
Sun 4/266:00 am
BUF
- EYW
1 stop5h 16m
American Airlines
Deal found 4/7![American Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:07 pm
EYW
- BUF
1 stop7h 00m
Multiple Airlines
Mon 7/132:50 pm
BUF
- EYW
2 stops21h 44m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/101:01 pm
EYW
- BUF
1 stop5h 43m
American Airlines
Mon 7/136:03 am
BUF
- EYW
1 stop7h 37m
American Airlines
Deal found 4/7![American Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:22 pm
EYW
- BUF
1 stop5h 28m
United Airlines
Sun 4/197:00 am
BUF
- EYW
1 stop7h 51m
United Airlines
Deal found 4/5![United Airlines logo]()
$534
Best flights from Key West to BuffaloDiscover carefully curated flight deals from Key West to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from Key West to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:51 am
EYW
- BUF
2 stops22h 43m
Multiple Airlines
Sun 4/263:58 pm
BUF
- EYW
1 stop20h 28m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:42 pm
EYW
- BUF
1 stop5h 37m
American Airlines
Sun 4/266:00 am
BUF
- EYW
1 stop5h 16m
American Airlines
Deal found 4/7![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:26 pm
EYW
- BUF
1 stop8h 05m
United Airlines
Sat 6/67:00 am
BUF
- EYW
1 stop8h 07m
United Airlines
Deal found 4/8![United Airlines logo]()
$667
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:07 pm
EYW
- BUF
1 stop7h 00m
Multiple Airlines
Mon 7/132:50 pm
BUF
- EYW
2 stops21h 44m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/101:01 pm
EYW
- BUF
1 stop5h 43m
American Airlines
Mon 7/136:03 am
BUF
- EYW
1 stop7h 37m
American Airlines
Deal found 4/7![American Airlines logo]()
$444
Last-minute flights from Key West to BuffaloDiscover last-minute flight deals from Key West to Buffalo. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to Buffalo. Data last updated April 10, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:22 pm
EYW
- BUF
1 stop5h 28m
United Airlines
Sun 4/197:00 am
BUF
- EYW
1 stop7h 51m
United Airlines
Deal found 4/5![United Airlines logo]()
$534
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:51 am
EYW
- BUF
2 stops22h 43m
Multiple Airlines
Sun 4/263:58 pm
BUF
- EYW
1 stop20h 28m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:42 pm
EYW
- BUF
1 stop5h 37m
American Airlines
Sun 4/266:00 am
BUF
- EYW
1 stop5h 16m
American Airlines
Deal found 4/7![American Airlines logo]()
$399
One-way flights from Key West to BuffaloSearch for one-way flight options from Key West to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from Key West to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/103:19 pm
EYW
- BUF
2 stops43h 22m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:05 pm
EYW
- BUF
1 stop6h 54m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/319:24 pm
EYW
- BUF
1 stop21h 35m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:46 am
EYW
- BUF
2 stops32h 18m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$152
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:26 pm
EYW
- BUF
1 stop8h 05m
United Airlines
Deal found 4/9![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:26 pm
EYW
- BUF
2 stops9h 33m
United Airlines
Deal found 4/8![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:18 pm
EYW
- BUF
1 stop5h 19m
Delta
Deal found 4/6![Delta logo]()
$387
Find flight deals from Key West to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $360 (Kiwi.com) |
One-way from | $139 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Key West to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 4/22
11:51 am-10:34 am
2 stops22h 43m
Buffalo
Sun 4/26
3:58 pm-12:26 pm
1 stop20h 28m
$360
Quickest round-trip
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 4/22
5:42 pm-11:19 pm
1 stop5h 37m
Buffalo
Sun 4/26
6:00 am-11:16 am
1 stop5h 16m
$399
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Fri 7/10
12:07 pm-7:07 pm
1 stop7h 00m
Buffalo
Mon 7/13
2:50 pm-12:34 pm
2 stops21h 44m
$406
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Fri 7/10
1:01 pm-6:44 pm
1 stop5h 43m
Buffalo
Mon 7/13
6:03 am-1:40 pm
1 stop7h 37m
$444
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 6/3
2:26 pm-10:31 pm
1 stop8h 05m
Buffalo
Sat 6/6
7:00 am-3:07 pm
1 stop8h 07m
$667
Cheapest one-way
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Sun 5/10
3:19 pm-10:41 am
2 stops43h 22m
$139
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Sun 5/31
9:24 pm-6:59 pm
1 stop21h 35m
$147
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 5/27
11:46 am-8:04 pm
2 stops32h 18m
$152
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 5/27
2:26 pm-10:31 pm
1 stop8h 05m
$334
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 6/4
2:26 pm-11:59 pm
2 stops9h 33m
$349
Showing 1-10 of 11 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Key West-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Key West with our price prediction graph.
EYW-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated April 10, 2026.
Read reviews from past customers who have flown Delta from Key West to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Related info for your journey
Find useful and relevant information for your journey from Key West to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 10, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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Key West and Buffalo flights
Browse other Key West and Buffalo flight options. Last updated on April 10, 2026.
Other flights from Key West
Browse through other flights departing from Key West. Flights are based on user searches made on Cheapflights and were last updated on April 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Key West to Buffalo
Discover the top airline that operate flights from Key West to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$259 | Average$393 | FlexibilityNo cancel fee | On-timeN/A |