$128+ Cheap flights from Key West to Buffalo (EYW - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BUF
Mar 27 — Apr 31
1 adult, Economy
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Find cheap flights from Key West to Buffalo with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to Buffalo
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Cheapest flights from Key West to BuffaloExplore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 25, 2026.
Explore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:49 am
EYW
- BUF
2 stops26h 28m
Multiple Airlines
Sun 4/128:59 pm
BUF
- EYW
1 stop15h 27m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:49 am
EYW
- BUF
2 stops26h 28m
Multiple Airlines
Sat 4/117:31 pm
BUF
- EYW
1 stop19h 29m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:49 am
EYW
- BUF
2 stops26h 28m
Multiple Airlines
Mon 4/136:55 pm
BUF
- EYW
1 stop17h 26m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/71:01 pm
EYW
- BUF
2 stops23h 16m
Multiple Airlines
Sat 4/117:31 pm
BUF
- EYW
1 stop19h 29m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/71:01 pm
EYW
- BUF
2 stops23h 16m
Multiple Airlines
Sun 4/128:59 pm
BUF
- EYW
1 stop15h 27m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:49 am
EYW
- BUF
2 stops26h 28m
Multiple Airlines
Fri 4/106:41 pm
BUF
- EYW
1 stop16h 23m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:39 pm
EYW
- BUF
2 stops23h 01m
Multiple Airlines
Sat 4/1811:44 am
BUF
- EYW
1 stop21h 22m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/71:01 pm
EYW
- BUF
2 stops23h 16m
Multiple Airlines
Mon 4/136:55 pm
BUF
- EYW
1 stop17h 26m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:23 pm
EYW
- BUF
1 stop5h 14m
Delta
Tue 4/216:00 am
BUF
- EYW
1 stop4h 46m
Delta
Deal found 2/23![Delta logo]()
$283
Best flights from Key West to BuffaloDiscover carefully curated flight deals from Key West to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 25, 2026.
Discover carefully curated flight deals from Key West to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 25, 2026.
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:23 pm
EYW
- BUF
1 stop5h 14m
Delta
Mon 4/2012:09 pm
BUF
- EYW
1 stop5h 14m
Delta
Deal found 2/23![Delta logo]()
$286
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:25 pm
EYW
- BUF
1 stop5h 21m
Delta
Mon 4/1312:09 pm
BUF
- EYW
1 stop7h 31m
Delta
Deal found 2/23![Delta logo]()
$341
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:25 pm
EYW
- BUF
1 stop5h 21m
Delta
Tue 4/1412:09 pm
BUF
- EYW
1 stop7h 31m
Delta
Deal found 2/23![Delta logo]()
$395
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:25 pm
EYW
- BUF
1 stop5h 21m
Delta
Wed 4/1510:13 am
BUF
- EYW
2 stops9h 27m
Delta
Deal found 2/23![Delta logo]()
$396
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:23 pm
EYW
- BUF
1 stop5h 14m
Delta
Thu 4/236:00 am
BUF
- EYW
1 stop13h 40m
Delta
Deal found 2/23![Delta logo]()
$425
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:35 pm
EYW
- BUF
1 stop9h 23m
Delta
Wed 8/512:09 pm
BUF
- EYW
1 stop7h 36m
Delta
Deal found 2/24![Delta logo]()
$425
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:00 pm
EYW
- BUF
1 stop5h 58m
Delta
Fri 8/76:00 am
BUF
- EYW
1 stop13h 45m
Delta
Deal found 2/24![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:45 am
EYW
- BUF
1 stop6h 50m
Delta
Thu 4/236:00 am
BUF
- EYW
1 stop13h 40m
Delta
Deal found 2/23![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:33 am
EYW
- BUF
1 stop8h 06m
Delta
Sat 4/186:15 am
BUF
- EYW
2 stops13h 25m
Delta
Deal found 2/23![Delta logo]()
$433
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 pm
EYW
- BUF
1 stop5h 58m
Delta
Thu 8/64:30 pm
BUF
- EYW
1 stop27h 15m
Delta
Deal found 2/24![Delta logo]()
$478
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:30 am
EYW
- BUF
2 stops15h 43m
Delta
Mon 4/137:00 am
BUF
- EYW
2 stops12h 40m
Delta
Deal found 2/23![Delta logo]()
$490
Last-minute flights from Key West to BuffaloDiscover last-minute flight deals from Key West to Buffalo. Data last updated February 25, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to Buffalo. Data last updated February 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:46 am
EYW
- BUF
1 stop24h 11m
Multiple Airlines
Thu 3/51:39 pm
BUF
- EYW
2 stops25h 14m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:46 am
EYW
- BUF
1 stop24h 11m
Multiple Airlines
Mon 3/24:45 pm
BUF
- EYW
1 stop19h 36m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:06 pm
EYW
- BUF
1 stop26h 46m
Multiple Airlines
Mon 3/24:45 pm
BUF
- EYW
1 stop19h 36m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:13 pm
EYW
- BUF
1 stop18h 36m
Multiple Airlines
Thu 3/51:39 pm
BUF
- EYW
2 stops25h 14m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:13 pm
EYW
- BUF
1 stop18h 36m
Multiple Airlines
Mon 3/24:45 pm
BUF
- EYW
1 stop19h 36m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:51 am
EYW
- BUF
1 stop22h 58m
Multiple Airlines
Sun 3/157:21 pm
BUF
- EYW
1 stop17h 05m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$357
One-way flights from Key West to BuffaloSearch for one-way flight options from Key West to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 25, 2026.
Search for one-way flight options from Key West to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/111:51 am
EYW
- BUF
1 stop23h 08m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/271:06 pm
EYW
- BUF
2 stops23h 36m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2511:54 am
EYW
- BUF
2 stops23h 15m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:06 pm
EYW
- BUF
2 stops24h 07m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/132:59 pm
EYW
- BUF
1 stop27h 42m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:38 pm
EYW
- BUF
2 stops17h 56m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$236
Find flight deals from Key West to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $229 (Kiwi.com) |
One-way from | $128 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 25, 2026.
Use the filters below to find and compare flights from Key West to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 4/15
6:23 pm-11:37 pm
1 stop5h 14m
Buffalo
Mon 4/20
12:09 pm-5:23 pm
1 stop5h 14m
$286
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 4/6
6:25 pm-11:46 pm
1 stop5h 21m
Buffalo
Mon 4/13
12:09 pm-7:40 pm
1 stop7h 31m
$341
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Tue 4/7
6:25 pm-11:46 pm
1 stop5h 21m
Buffalo
Tue 4/14
12:09 pm-7:40 pm
1 stop7h 31m
$395
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 4/6
6:25 pm-11:46 pm
1 stop5h 21m
Buffalo
Wed 4/15
10:13 am-7:40 pm
2 stops9h 27m
$396
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 4/15
6:23 pm-11:37 pm
1 stop5h 14m
Buffalo
Thu 4/23
6:00 am-7:40 pm
1 stop13h 40m
$425
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Fri 7/17
2:35 pm-11:58 pm
1 stop9h 23m
Buffalo
Wed 8/5
12:09 pm-7:45 pm
1 stop7h 36m
$425
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 7/16
6:00 pm-11:58 pm
1 stop5h 58m
Buffalo
Fri 8/7
6:00 am-7:45 pm
1 stop13h 45m
$428
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 4/16
11:45 am-6:35 pm
1 stop6h 50m
Buffalo
Thu 4/23
6:00 am-7:40 pm
1 stop13h 40m
$428
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Fri 4/17
7:33 am-3:39 pm
1 stop8h 06m
Buffalo
Sat 4/18
6:15 am-7:40 pm
2 stops13h 25m
$433
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Tue 7/14
6:00 pm-11:58 pm
1 stop5h 58m
Buffalo
Thu 8/6
4:30 pm-7:45 pm
1 stop27h 15m
$478
Showing 1-10 of 19 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Key West-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Key West with our price prediction graph.
EYW-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Key West to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
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