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$243+ Cheap flights from San Francisco (SFO) to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — BRU
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from San Francisco to Brussels are usually found in January or March, booked 52 days in advance, depart on a Tuesday or Wednesday and return on a Sunday

Cheap flight deals from San Francisco to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$447
(SmartFares)

One-way from

$243
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$745
From San Francisco to Brussels
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One-way flight from San Francisco to Brussels
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Highest demand for flights based on searches. 19% potential increase in price ($197 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($31 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Francisco to Brussels

Cheapest flights from San Francisco to Brussels
Explore the most affordable flight options available from San Francisco to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/207:00 amSFO - BRU
2 stops17h 40mScandinavian Airlines
Fri 10/3110:20 amBRU - SFO
1 stop13h 15mScandinavian Airlines
Deal found 9/13$449
This Scandinavian Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:35 pmSFO - BRU
2 stops23h 15mScandinavian Airlines
Wed 11/58:30 pmBRU - SFO
1 stop27h 05mScandinavian Airlines
Deal found 9/14$454
This CrystalTravel deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:40 pmSFO - BRU
1 stop12h 50mScandinavian Airlines
Mon 11/2410:20 amBRU - SFO
1 stop13h 15mScandinavian Airlines
Deal found 9/14$460
This Scandinavian Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/207:00 amSFO - BRU
2 stops17h 40mScandinavian Airlines
Sat 11/18:30 pmBRU - SFO
1 stop27h 05mScandinavian Airlines
Deal found 9/14$468
This CrystalTravel deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:40 pmSFO - BRU
1 stop12h 50mScandinavian Airlines
Sat 11/2210:20 amBRU - SFO
1 stop13h 15mScandinavian Airlines
Deal found 9/14$470
This Scandinavian Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1212:30 pmSFO - BRU
2 stops22h 20mScandinavian Airlines
Wed 11/1911:30 amBRU - SFO
2 stops36h 05mScandinavian Airlines
Deal found 9/14$472
This oojo deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/134:40 pmSFO - BRU
2 stops19h 15mScandinavian Airlines
Sun 11/2310:20 amBRU - SFO
1 stop13h 15mScandinavian Airlines
Deal found 9/14$474
This oojo deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/164:40 pmSFO - BRU
1 stop18h 10mScandinavian Airlines
Fri 11/2111:30 amBRU - SFO
2 stops36h 05mScandinavian Airlines
Deal found 9/13$476
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/134:40 pmSFO - BRU
1 stop18h 10mScandinavian Airlines
Mon 11/2410:20 amBRU - SFO
1 stop13h 15mScandinavian Airlines
Deal found 9/14$477
This CrystalTravel deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/134:40 pmSFO - BRU
1 stop18h 10mScandinavian Airlines
Thu 11/2010:20 amBRU - SFO
1 stop13h 15mScandinavian Airlines
Deal found 9/14$479
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/228:30 amSFO - CRL
2 stops18h 30mMultiple Airlines
Mon 10/275:15 pmCRL - SFO
2 stops32h 15mMultiple Airlines
Deal found 9/15$539
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:25 amSFO - CRL
2 stops24h 55mMultiple Airlines
Fri 11/216:25 amCRL - SFO
2 stops23h 57mMultiple Airlines
Deal found 9/14$597

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from San Francisco to Brussels that are best for you.

Fly from

San Francisco

Fly to

Brussels

Route

Depart

Return

Price

San FranciscoBrussels

SFO - BRU

SFOBRU

San Francisco

Wed 10/29

12:35 pm-7:50 pm

2 stops23h 15m

Brussels Bruxelles-National

Wed 11/5

8:30 pm-2:35 pm

1 stop27h 05m

$454

San FranciscoBrussels

SFO - BRU

SFOBRU

San Francisco

Mon 10/13

3:30 pm-6:30 pm

2 stops18h 00m

Brussels Bruxelles-National

Mon 10/27

8:30 pm-4:10 pm

1 stop27h 40m

$480

San FranciscoBrussels

SFO - BRU

SFOBRU

San Francisco

Tue 10/14

12:35 pm-7:50 pm

2 stops22h 15m

Brussels Bruxelles-National

Fri 10/24

7:10 pm-4:30 pm

1 stop30h 20m

$480

San FranciscoBrussels

SFO - BRU

SFOBRU

San Francisco

Wed 10/15

12:35 pm-6:30 pm

2 stops20h 55m

Brussels Bruxelles-National

Mon 10/27

8:30 pm-4:10 pm

1 stop27h 40m

$480

San FranciscoBrussels

SFO - BRU

SFOBRU

San Francisco

Wed 3/4

1:00 pm-7:50 pm

2 stops21h 50m

Brussels Bruxelles-National

Sun 3/8

8:30 pm-3:35 pm

1 stop27h 05m

$480

San FranciscoBrussels

SFO - BRU

SFOBRU

San Francisco

Thu 11/6

4:40 pm-7:50 pm

1 stop18h 10m

Brussels Bruxelles-National

Fri 11/21

11:30 am-2:35 pm

2 stops36h 05m

$484

San FranciscoBrussels

SFO - BRU

SFOBRU

San Francisco

Mon 10/13

3:30 pm-6:30 pm

2 stops18h 00m

Brussels Bruxelles-National

Fri 10/24

7:00 pm-4:30 pm

2 stops30h 30m

$502

San FranciscoBrussels

SFO - BRU

SFOBRU

San Francisco

Sat 3/14

5:40 pm-2:30 pm

1 stop12h 50m

Brussels Bruxelles-National

Mon 4/13

10:20 am-2:40 pm

1 stop13h 20m

$520

San FranciscoBrussels

SFO - BRU

SFOBRU

San Francisco

Sat 3/14

5:40 pm-2:30 pm

1 stop12h 50m

Brussels Bruxelles-National

Fri 4/17

10:20 am-2:40 pm

1 stop13h 20m

$520

San FranciscoBrussels

SFO - BRU

SFOBRU

San Francisco

Tue 10/28

7:00 am-9:40 am

2 stops18h 40m

Brussels Bruxelles-National

Tue 11/4

8:30 pm-11:23 pm

2 stops35h 53m

$520

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 34 results
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Best time to book a flight from San Francisco to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Brussels

How far ahead should I book a flight from San Francisco to Brussels?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Brussels. Price data was last updated on September 12, 2025.

Booking 52 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Brussels. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Francisco to Brussels?

Currently, November is the cheapest month in which you can book a flight from San Francisco to Brussels (average of $614). Flying from San Francisco to Brussels in June is currently the most expensive (average of $1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to BRU?

Find hourly flight availability from San Francisco to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from San Francisco to Brussels, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 43% versus a flight in the morning.

What is the cheapest day to fly from San Francisco to Brussels?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Brussels. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Brussels flight should consider departing on Monday afternoons when fares are most often at their lowest. Friday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated September 15, 2025.
Read through reviews of airlines operating flights from San Francisco to Brussels, such as Scandinavian Airlines, United Airlines, and Brussels Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Scandinavian Airlines
7.4
Good
1,484 reviews

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.7

Entertainment

6.7

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Jun 2025

ATH - CPH

The flight crew of Aegean were very nice. I travelled coach, so comfort and such is based on that. However, their ground crew have a serious scam going. I flew from Athens to Santorini with all carry on baggage, nothing checked. On the return flight to Athens my baggage miraculously was "too big" for the over head compartments and had to pay to check my bags. I even told them I didn't pay coming over. Their answer? "I don't care." They hit everyone going back to Athens like that...that's a serious money maker at a minimum of 40 Euros per bag.
Scandinavian Airlines
7.4
Good
1,484 reviews
Scandinavian Airlines
7.4
Good
1,484 reviews

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.7

Entertainment

6.7

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Jun 2025

ATH - CPH

The flight crew of Aegean were very nice. I travelled coach, so comfort and such is based on that. However, their ground crew have a serious scam going. I flew from Athens to Santorini with all carry on baggage, nothing checked. On the return flight to Athens my baggage miraculously was "too big" for the over head compartments and had to pay to check my bags. I even told them I didn't pay coming over. Their answer? "I don't care." They hit everyone going back to Athens like that...that's a serious money maker at a minimum of 40 Euros per bag.
United Airlines
7.4
Good
8,929 reviews
Scandinavian Airlines
7.4
Good
1,484 reviews

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.7

Entertainment

6.7

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Jun 2025

ATH - CPH

The flight crew of Aegean were very nice. I travelled coach, so comfort and such is based on that. However, their ground crew have a serious scam going. I flew from Athens to Santorini with all carry on baggage, nothing checked. On the return flight to Athens my baggage miraculously was "too big" for the over head compartments and had to pay to check my bags. I even told them I didn't pay coming over. Their answer? "I don't care." They hit everyone going back to Athens like that...that's a serious money maker at a minimum of 40 Euros per bag.
Brussels Airlines
7.3
Good
359 reviews
Scandinavian Airlines
7.4
Good
1,484 reviews

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.7

Entertainment

6.7

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Jun 2025

ATH - CPH

The flight crew of Aegean were very nice. I travelled coach, so comfort and such is based on that. However, their ground crew have a serious scam going. I flew from Athens to Santorini with all carry on baggage, nothing checked. On the return flight to Athens my baggage miraculously was "too big" for the over head compartments and had to pay to check my bags. I even told them I didn't pay coming over. Their answer? "I don't care." They hit everyone going back to Athens like that...that's a serious money maker at a minimum of 40 Euros per bag.
Aer Lingus
7.2
Good
1,270 reviews
Scandinavian Airlines
7.4
Good
1,484 reviews

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.7

Entertainment

6.7

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Jun 2025

ATH - CPH

The flight crew of Aegean were very nice. I travelled coach, so comfort and such is based on that. However, their ground crew have a serious scam going. I flew from Athens to Santorini with all carry on baggage, nothing checked. On the return flight to Athens my baggage miraculously was "too big" for the over head compartments and had to pay to check my bags. I even told them I didn't pay coming over. Their answer? "I don't care." They hit everyone going back to Athens like that...that's a serious money maker at a minimum of 40 Euros per bag.
Lufthansa
6.8
Okay
7,407 reviews
Scandinavian Airlines
7.4
Good
1,484 reviews

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.7

Entertainment

6.7

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Jun 2025

ATH - CPH

The flight crew of Aegean were very nice. I travelled coach, so comfort and such is based on that. However, their ground crew have a serious scam going. I flew from Athens to Santorini with all carry on baggage, nothing checked. On the return flight to Athens my baggage miraculously was "too big" for the over head compartments and had to pay to check my bags. I even told them I didn't pay coming over. Their answer? "I don't care." They hit everyone going back to Athens like that...that's a serious money maker at a minimum of 40 Euros per bag.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to Brussels?

    San Francisco (SFO) is the airport you will fly out of if you book a flight from San Francisco to Brussels. You should not have trouble finding flights to Brussels from San Francisco; the airport handles an average of 0 outbound flights to Brussels per day. You should also have plenty of airline options to choose from since 13 airlines have flights from the San Francisco airport to Brussels. It is only a 11.8 mi journey to San Francisco (SFO) from San Francisco’s city center.

  • How long is the flight from San Francisco to Brussels?

    Airlines like Scandinavian Airlines fly from San Francisco to Brussels in about 23h 15m. The time it takes to get you to your destination can typically vary by up to . The distance from San Francisco to Brussels is about 5522 mi.

  • What are the cheapest airlines flying from San Francisco to Brussels round-trip?

    Scandinavian Airlines, at $489, was found to be the cheapest airline from San Francisco to Brussels.Alternate airlines to your destination round-trip include TAP AIR PORTUGAL and Air France. Scandinavian Airlines is currently priced 41% below the average price you’ll pay for this route.

  • Where are the most common layover locations when flying from San Francisco to Brussels?

    The most popular layover on flights from San Francisco to Brussels is Copenhagen.

  • What are some popular things to do or see while on a layover in Copenhagen?

    Tivoli, Rådhuspladsen, and Kongens Nytorv are currently the most popular points of interest in Copenhagen at the moment. Tivoli, Rådhuspladsen, and Kongens Nytorv can be accessed by traveling approximately 5.3 mi, 5.2 mi, and 5.1 mi, respectively from Kastrup Copenhagen. Travelers can book a car rental at Kastrup Copenhagen for about $53 per day to make their sightseeing more efficient.

  • Where are the least popular layover locations for San Francisco to Brussels flights?

    The least popular layover on flights from San Francisco to Brussels is Frankfurt am Main.

  • Can I find deals for flights from San Francisco to Brussels that include hotel bookings?

    Yes. In addition to deals on San Francisco to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Brussels.

  • Can I find deals for business class flights from San Francisco to Brussels?

    Yes. Cheapflights offers flight deals from San Francisco to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Brussels?

    Currently, November is the cheapest month in which you can book a flight from San Francisco to Brussels (average of $614). Flying from San Francisco to Brussels in June is currently the most expensive (average of $1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from San Francisco to Brussels

Discover the top 10 airlines that operate flights from San Francisco to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Scandinavian AirlinesCheapest$489Average$666FlexibilityNo cancel feeOn-time77%
TAP AIR PORTUGALCheapest$490Average$881FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$520Average$870FlexibilityNo cancel feeOn-time77%
DeltaCheapest$520Average$1,405FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$522Average$890FlexibilityNo cancel feeOn-time70%
KLMCheapest$530Average$950FlexibilityNo cancel feeOn-time75%
Aer LingusCheapest$539Average$871FlexibilityNo cancel feeOn-timeN/A
SWISSCheapest$628Average$1,167FlexibilityNo cancel feeOn-time79%
Brussels AirlinesCheapest$632Average$849FlexibilityNo cancel feeOn-timeN/A
Turkish AirlinesCheapest$634Average$701FlexibilityNo cancel feeOn-time77%

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