$245+ Cheap flights from San Francisco (SFO) to Brussels
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — BRU
Mar 23 — Mar 301
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Francisco to Brussels with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Brussels
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Francisco to BrusselsExplore the most affordable flight options available from San Francisco to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2026.
Explore the most affordable flight options available from San Francisco to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2026.
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:40 pm
SFO
- BRU
1 stop12h 50m
Scandinavian Airlines
Wed 4/811:20 am
BRU
- SFO
2 stops36h 20m
Scandinavian Airlines
Deal found 2/19![Scandinavian Airlines logo]()
$488
This Flightnetwork deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:40 pm
SFO
- BRU
1 stop12h 50m
Scandinavian Airlines
Sun 4/57:10 pm
BRU
- SFO
1 stop28h 30m
Scandinavian Airlines
Deal found 2/20![Scandinavian Airlines logo]()
$493
This oojo deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:40 pm
SFO
- BRU
1 stop17h 10m
Scandinavian Airlines
Wed 4/13:15 pm
BRU
- SFO
1 stop32h 25m
Scandinavian Airlines
Deal found 2/20![Scandinavian Airlines logo]()
$494
This oojo deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/294:45 pm
SFO
- BRU
1 stop12h 50m
Scandinavian Airlines
Tue 10/1310:20 am
BRU
- SFO
1 stop13h 20m
Scandinavian Airlines
Deal found 2/20![Scandinavian Airlines logo]()
$506
This FlightHub deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:45 pm
SFO
- BRU
1 stop31h 55m
Scandinavian Airlines
Mon 5/1111:20 am
BRU
- SFO
2 stops36h 20m
Scandinavian Airlines
Deal found 2/20![Scandinavian Airlines logo]()
$509
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:40 pm
SFO
- BRU
2 stops33h 10m
Scandinavian Airlines
Fri 12/1110:20 am
BRU
- SFO
1 stop13h 15m
Scandinavian Airlines
Deal found 2/19![Scandinavian Airlines logo]()
$516
This CrystalTravel deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/74:45 pm
SFO
- BRU
1 stop21h 15m
Scandinavian Airlines
Sun 9/137:00 pm
BRU
- SFO
2 stops28h 40m
Scandinavian Airlines
Deal found 2/21![Scandinavian Airlines logo]()
$524
This FlightHub deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:45 pm
SFO
- BRU
1 stop18h 05m
Scandinavian Airlines
Sun 4/268:30 pm
BRU
- SFO
1 stop27h 10m
Scandinavian Airlines
Deal found 2/20![Scandinavian Airlines logo]()
$525
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:10 am
SFO
- CRL
3 stops26h 30m
Multiple Airlines
Mon 4/276:00 pm
CRL
- SFO
2 stops27h 40m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$592
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:10 am
SFO
- CRL
2 stops25h 30m
Multiple Airlines
Tue 4/286:55 am
CRL
- SFO
2 stops23h 26m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$645
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:05 am
SFO
- CRL
2 stops21h 30m
Multiple Airlines
Tue 5/196:55 am
CRL
- SFO
2 stops23h 07m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$676
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/12:40 pm
SFO
- CRL
3 stops23h 05m
Multiple Airlines
Fri 3/68:55 am
CRL
- SFO
2 stops19h 40m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$718
Best flights from San Francisco to BrusselsDiscover carefully curated flight deals from San Francisco to Brussels that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 21, 2026.
Discover carefully curated flight deals from San Francisco to Brussels that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 21, 2026.
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:10 am
SFO
- CRL
3 stops26h 30m
Multiple Airlines
Mon 4/276:00 pm
CRL
- SFO
2 stops27h 40m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$592
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:50 pm
SFO
- BRU
1 stop22h 10m
United Airlines
Wed 4/299:25 am
BRU
- SFO
1 stop20h 56m
United Airlines
Deal found 2/17![United Airlines logo]()
$599
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
SFO
- BRU
1 stop16h 40m
Delta
Mon 4/2710:25 am
BRU
- SFO
1 stop34h 20m
Delta
Deal found 2/20![Delta logo]()
$606
This ITA Airways deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:15 pm
SFO
- BRU
2 stops32h 20m
ITA Airways
Mon 5/48:15 pm
BRU
- SFO
2 stops26h 00m
ITA Airways
Deal found 2/20![ITA Airways logo]()
$615
This Finnair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/131:40 pm
SFO
- BRU
2 stops23h 55m
Finnair
Mon 4/277:05 pm
BRU
- SFO
2 stops33h 10m
Finnair
Deal found 2/20![Finnair logo]()
$628
This Scandinavian Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:00 am
SFO
- BRU
2 stops17h 40m
Scandinavian Airlines
Sat 3/78:30 pm
BRU
- SFO
1 stop27h 05m
Scandinavian Airlines
Deal found 2/18![Scandinavian Airlines logo]()
$645
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:20 am
SFO
- BRU
2 stops19h 55m
United Airlines
Thu 4/309:25 am
BRU
- SFO
1 stop20h 56m
United Airlines
Deal found 2/20![United Airlines logo]()
$603
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:10 am
SFO
- CRL
2 stops25h 30m
Multiple Airlines
Tue 4/286:55 am
CRL
- SFO
2 stops23h 26m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$645
This Scandinavian Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:25 am
SFO
- BRU
2 stops18h 15m
Scandinavian Airlines
Mon 3/3011:20 am
BRU
- SFO
2 stops36h 20m
Scandinavian Airlines
Deal found 2/18![Scandinavian Airlines logo]()
$648
This Finnair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:30 am
SFO
- BRU
2 stops26h 05m
Finnair
Mon 4/137:05 pm
BRU
- SFO
2 stops33h 10m
Finnair
Deal found 2/20![Finnair logo]()
$655
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1712:50 pm
SFO
- BRU
1 stop15h 25m
United Airlines
Wed 5/279:25 am
BRU
- SFO
1 stop20h 37m
United Airlines
Deal found 2/20![United Airlines logo]()
$633
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:50 pm
SFO
- BRU
1 stop15h 25m
United Airlines
Thu 4/309:25 am
BRU
- SFO
1 stop20h 56m
United Airlines
Deal found 2/20![United Airlines logo]()
$649
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:35 pm
SFO
- BRU
1 stop18h 25m
United Airlines
Fri 5/12:25 pm
BRU
- SFO
1 stop14h 35m
United Airlines
Deal found 2/20![United Airlines logo]()
$653
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:40 pm
SFO
- CRL
1 stop16h 20m
Multiple Airlines
Wed 4/297:15 pm
CRL
- SFO
2 stops29h 55m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$792
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:40 pm
SFO
- CRL
1 stop16h 20m
Multiple Airlines
Mon 7/610:00 pm
CRL
- SFO
2 stops47h 20m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$866
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:30 am
SFO
- CRL
2 stops22h 05m
Multiple Airlines
Wed 4/87:45 am
CRL
- SFO
2 stops22h 36m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$879
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:40 pm
SFO
- CRL
1 stop16h 20m
Multiple Airlines
Tue 7/77:55 am
CRL
- SFO
2 stops41h 00m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$900
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:10 am
SFO
- CRL
3 stops26h 50m
Multiple Airlines
Wed 9/25:35 pm
CRL
- SFO
2 stops29h 55m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$926
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:10 am
SFO
- CRL
3 stops26h 50m
Multiple Airlines
Fri 9/46:35 pm
CRL
- SFO
2 stops32h 00m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$928
Last-minute flights from San Francisco to BrusselsDiscover last-minute flight deals from San Francisco to Brussels. Data last updated February 21, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Brussels. Data last updated February 21, 2026 and is based on user searches.
This oojo deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:40 pm
SFO
- BRU
1 stop12h 50m
Scandinavian Airlines
Fri 3/67:15 pm
BRU
- SFO
1 stop28h 20m
Scandinavian Airlines
Deal found 2/18![Scandinavian Airlines logo]()
$534
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/12:40 pm
SFO
- CRL
3 stops23h 05m
Multiple Airlines
Fri 3/68:55 am
CRL
- SFO
2 stops19h 40m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$718
This CrystalTravel deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:40 pm
SFO
- BRU
1 stop16h 55m
Scandinavian Airlines
Thu 3/510:20 am
BRU
- SFO
1 stop13h 15m
Scandinavian Airlines
Deal found 2/19![Scandinavian Airlines logo]()
$545
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:30 am
SFO
- CRL
3 stops30h 00m
Multiple Airlines
Fri 3/135:40 pm
CRL
- SFO
2 stops30h 05m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$1,001
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/74:35 pm
SFO
- CRL
2 stops21h 10m
Multiple Airlines
Fri 3/135:40 pm
CRL
- SFO
2 stops30h 05m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$802
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/144:05 pm
SFO
- CRL
2 stops20h 55m
Multiple Airlines
Fri 3/204:30 pm
CRL
- SFO
2 stops29h 35m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$950
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:40 pm
SFO
- BRU
1 stop12h 50m
Scandinavian Airlines
Wed 4/811:20 am
BRU
- SFO
2 stops36h 20m
Scandinavian Airlines
Deal found 2/19![Scandinavian Airlines logo]()
$488
This Flightnetwork deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:40 pm
SFO
- BRU
1 stop12h 50m
Scandinavian Airlines
Sun 4/57:10 pm
BRU
- SFO
1 stop28h 30m
Scandinavian Airlines
Deal found 2/20![Scandinavian Airlines logo]()
$493
This oojo deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/234:05 pm
SFO
- BRU
1 stop17h 55m
ITA Airways
Mon 3/3011:35 am
BRU
- SFO
1 stop34h 40m
ITA Airways
Deal found 2/21![ITA Airways logo]()
$548
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:30 am
SFO
- CRL
2 stops22h 05m
Multiple Airlines
Wed 4/87:45 am
CRL
- SFO
2 stops22h 36m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$879
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:30 pm
SFO
- CRL
2 stops30h 50m
Multiple Airlines
Mon 4/139:30 pm
CRL
- SFO
1 stop29h 25m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$942
This oojo deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:40 pm
SFO
- BRU
1 stop17h 10m
Scandinavian Airlines
Wed 4/13:15 pm
BRU
- SFO
1 stop32h 25m
Scandinavian Airlines
Deal found 2/20![Scandinavian Airlines logo]()
$494
One-way flights from San Francisco to BrusselsSearch for one-way flight options from San Francisco to Brussels. Find affordable one-way fares based on user searches. Data last updated February 21, 2026.
Search for one-way flight options from San Francisco to Brussels. Find affordable one-way fares based on user searches. Data last updated February 21, 2026.
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:15 pm
SFO
- BRU
1 stop17h 45m
ITA Airways
Deal found 2/17![ITA Airways logo]()
$245
This TravelUp deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:50 pm
SFO
- BRU
1 stop15h 25m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:40 pm
SFO
- BRU
1 stop18h 05m
Aer Lingus
Deal found 2/21![Aer Lingus logo]()
$254
This Trip.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:15 pm
SFO
- BRU
1 stop17h 45m
ITA Airways
Deal found 2/18![ITA Airways logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
SFO
- BRU
3 stops21h 55m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$278
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:15 pm
SFO
- BRU
1 stop34h 30m
ITA Airways
Deal found 2/18![ITA Airways logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:10 pm
SFO
- CRL
2 stops40h 05m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:38 pm
SFO
- BRU
3 stops53h 17m
Multiple Airlines
Deal found 2/17![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:40 pm
SFO
- CRL
1 stop30h 00m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:49 pm
SFO
- BRU
3 stops35h 06m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:10 pm
SFO
- CRL
2 stops41h 15m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:40 pm
SFO
- CRL
2 stops20h 20m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$322
Find flight deals from San Francisco to Brussels
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 21, 2026.
Round-trip from | $488 (Mytrip) |
|---|---|
One-way from | $245 (Mytrip) |
Popular in | June |
Cheapest in | February |
Average price | $530 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
Use the filters below to find and compare flights from San Francisco to Brussels that are best for you.
Fly from
San Francisco
Fly to
Brussels
Route
Depart
Return
Price
San FranciscoBrussels
SFO - CRL
SFOCRL
San Francisco
Mon 4/13
8:10 am-7:40 pm
3 stops26h 30m
Charleroi Brussels
Mon 4/27
6:00 pm-12:40 pm
2 stops27h 40m
$592
San FranciscoBrussels
SFO - BRU
SFOBRU
San Francisco
Wed 4/22
12:50 pm-8:00 pm
1 stop22h 10m
Brussels Bruxelles-National
Wed 4/29
9:25 am-9:21 pm
1 stop20h 56m
$599
San FranciscoBrussels
SFO - BRU
SFOBRU
San Francisco
Wed 4/22
8:20 am-1:15 pm
2 stops19h 55m
Brussels Bruxelles-National
Thu 4/30
9:25 am-9:21 pm
1 stop20h 56m
$603
San FranciscoBrussels
SFO - BRU
SFOBRU
San Francisco
Mon 4/13
6:00 am-7:40 am
1 stop16h 40m
Brussels Bruxelles-National
Mon 4/27
10:25 am-11:45 am
1 stop34h 20m
$606
San FranciscoBrussels
SFO - BRU
SFOBRU
San Francisco
Tue 4/21
3:15 pm-8:35 am
2 stops32h 20m
Brussels Bruxelles-National
Mon 5/4
8:15 pm-1:15 pm
2 stops26h 00m
$615
San FranciscoBrussels
SFO - BRU
SFOBRU
San Francisco
Mon 4/13
1:40 pm-10:35 pm
2 stops23h 55m
Brussels Bruxelles-National
Mon 4/27
7:05 pm-7:15 pm
2 stops33h 10m
$628
San FranciscoBrussels
SFO - BRU
SFOBRU
San Francisco
Sun 5/17
12:50 pm-1:15 pm
1 stop15h 25m
Brussels Bruxelles-National
Wed 5/27
9:25 am-9:02 pm
1 stop20h 37m
$633
San FranciscoBrussels
SFO - BRU
SFOBRU
San Francisco
Wed 3/4
7:00 am-9:40 am
2 stops17h 40m
Brussels Bruxelles-National
Sat 3/7
8:30 pm-2:35 pm
1 stop27h 05m
$645
San FranciscoBrussels
SFO - CRL
SFOCRL
San Francisco
Mon 4/13
8:10 am-6:40 pm
2 stops25h 30m
Charleroi Brussels
Tue 4/28
6:55 am-9:21 pm
2 stops23h 26m
$645
San FranciscoBrussels
SFO - BRU
SFOBRU
San Francisco
Tue 3/24
7:25 am-9:40 am
2 stops18h 15m
Brussels Bruxelles-National
Mon 3/30
11:20 am-2:40 pm
2 stops36h 20m
$648
Showing 1-10 of 37 results
Best time to book a flight from San Francisco to Brussels
Have a flexible travel schedule? Discover the best time to fly to Brussels from San Francisco with our price prediction graph.
SFO-BR1
SFO-BRU
SFO-CRL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Brussels
SFO-BR1
SFO-BRU
SFO-CRL
How far ahead should I book a flight from San Francisco to Brussels?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Brussels. Price data was last updated on February 20, 2026.
Booking 60 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Brussels. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Francisco to Brussels?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Brussels (average of $432). Flying from San Francisco to Brussels in June is currently the most expensive (average of $784). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Brussels?
Reviews of airlines servicing Brussels
Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated February 21, 2026.
Read through reviews of airlines operating flights from San Francisco to Brussels, such as United Airlines, Scandinavian Airlines, and Brussels Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Reviews
1 / 20
4.0
OkayThomas,Mar 2025
SFO - TPE
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Reviews
1 / 20
4.0
OkayThomas,Mar 2025
SFO - TPE
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Reviews
1 / 20
4.0
OkayThomas,Mar 2025
SFO - TPE
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Reviews
1 / 20
4.0
OkayThomas,Mar 2025
SFO - TPE
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Reviews
1 / 20
4.0
OkayThomas,Mar 2025
SFO - TPE
Crew
8.1
Comfort
7.3
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Reviews
1 / 20
4.0
OkayThomas,Mar 2025
SFO - TPE
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from San Francisco
Popular flights
Alternative routes for San Francisco to Brussels
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Brussels by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to Brussels by cabin class
Find flights from San Francisco to Brussels, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and Brussels flights
Browse other San Francisco and Brussels flight options. Last updated on February 21, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on February 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 10 airlines flying from San Francisco to Brussels
Discover the top 10 airlines that operate flights from San Francisco to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$485 | Average$591 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$556 | Average$852 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$582 | Average$865 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$591 | Average$780 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$593 | Average$1,148 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$625 | Average$830 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$632 | Average$795 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$633 | Average$864 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$640 | Average$1,025 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$649 | Average$742 | FlexibilityNo cancel fee | On-time77% |