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$332+ Cheap flights from Charleston (CHS) to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BRU
Mar 13 — Mar 201
Fri 3/13
Fri 3/20
1 adult, Economy
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Cheap flight deals from Charleston to Brussels

Cheapest flights from Charleston to Brussels
Explore the most affordable flight options available from Charleston to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.

This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:51 pm
CHS
-
BRU
2 stops16h 24m
United Airlines
Tue 4/289:25 am
BRU
-
CHS
2 stops35h 28m
United Airlines
Deal found 2/9$485
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:45 pm
CHS
-
BRU
2 stops32h 05m
United Airlines
Sun 3/2210:00 am
BRU
-
CHS
2 stops39h 57m
United Airlines
Deal found 2/11$493
This Cheapflightsfares deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:55 pm
CHS
-
BRU
2 stops24h 15m
Lufthansa
Tue 4/2810:30 am
BRU
-
CHS
2 stops19h 29m
Lufthansa
Deal found 2/8$503
This KLM deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:55 am
CHS
-
BRU
1 stop14h 45m
KLM
Tue 4/289:45 am
BRU
-
CHS
1 stop15h 07m
KLM
Deal found 2/9$508
This Gurufare deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/142:48 pm
CHS
-
BRU
2 stops15h 02m
Multiple Airlines
Sun 3/229:30 am
BRU
-
CHS
2 stops40h 27m
Multiple Airlines
Deal found 2/9$586
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:30 pm
CHS
-
BRU
2 stops16h 45m
United Airlines
Tue 10/209:25 am
BRU
-
CHS
2 stops41h 39m
United Airlines
Deal found 2/10$624

Find flight deals from Charleston to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 11, 2026.

Round-trip from

$485
(United Airlines)

One-way from

$332
(Kiwi.com)
From Charleston to Brussels
Search Deals
One-way flight from Charleston to Brussels
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Charleston to Brussels that are best for you.

Fly from

Charleston

Fly to

Brussels

Route

Depart

Return

Price

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 4/22

2:51 pm-1:15 pm

2 stops16h 24m

Brussels Bruxelles-National

Tue 4/28

9:25 am-2:53 pm

2 stops35h 28m

$485

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Sat 3/14

6:45 pm-7:50 am

2 stops32h 05m

Brussels Bruxelles-National

Sun 3/22

10:00 am-8:57 pm

2 stops39h 57m

$493

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 4/22

4:55 pm-11:10 pm

2 stops24h 15m

Brussels Bruxelles-National

Tue 4/28

10:30 am-11:59 pm

2 stops19h 29m

$503

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 4/22

10:55 am-7:40 am

1 stop14h 45m

Brussels Bruxelles-National

Tue 4/28

9:45 am-9:55 pm

1 stop18h 10m

$508

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 5/6

9:35 am-1:35 pm

2 stops22h 00m

$332

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Tue 5/5

3:35 pm-1:35 pm

2 stops40h 00m

$332

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Tue 5/5

4:30 pm-8:45 pm

2 stops22h 15m

$343

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Fri 5/29

6:43 pm-7:50 am

2 stops55h 07m

$361

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Tue 5/5

1:06 pm-9:00 am

1 stop13h 54m

$400

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Tue 5/5

2:48 pm-7:15 am

1 stop10h 27m

$400

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/9

Showing 1-10 of 14 results
1
2

Best time to book a flight from Charleston to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Brussels
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated February 11, 2026.
See what other customers who have flown with United Airlines from Charleston to Brussels have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,274 reviews

Comfort

7.3

Crew

8.1

Entertainment

7.1

Boarding

7.7

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,274 reviews
United Airlines
7.4
Good
9,274 reviews

Comfort

7.3

Crew

8.1

Entertainment

7.1

Boarding

7.7

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Charleston to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Brussels?

    Located just 10.2 mi from the city center, Charleston is the airport most travelers will use when flying to Brussels from Charleston. Booking flights from Charleston (CHS) to Brussels should be relatively easy as there are 0 daily outbound flights to Brussels from 1 airline.

  • How long is the flight from Charleston to Brussels?

    A quick flight from Charleston to Brussels can take about 16h 24m. United Airlines provides one of the quickest options available for as low as $485. There are 4269 mi between Charleston and Brussels.

  • What is the cheapest airline to fly from Charleston to Brussels round-trip?

    Flying on United Airlines is currently your cheapest option to Brussels, with prices starting at $626.

  • Can I find deals for flights from Charleston to Brussels that include hotel bookings?

    Yes. In addition to deals on Charleston to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Brussels.

  • Can I find deals for business class flights from Charleston to Brussels?

    Yes. Cheapflights offers flight deals from Charleston to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Charleston to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Bruxelles-National flights
Charleston to Bruxelles-National flights
Myrtle Beach to Bruxelles-National flights
Columbia to Bruxelles-National flights

Top airline flying from Charleston to Brussels

Discover the top airline that operate flights from Charleston to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$626Average$998FlexibilityNo cancel feeOn-time69%

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