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$656+ Cheap flights from Charleston (CHS) to Brussels

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BRU
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from Charleston to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Round-trip from

$656
(Delta)
From Charleston to Brussels
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Find flight deals from Charleston to Brussels

Cheapest flights from Charleston to Brussels
Explore the most affordable flight options available from Charleston to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:33 amCHS - BRU
1 stop15h 22mUnited Airlines
Wed 12/1011:15 amBRU - CHS
1 stop12h 57mUnited Airlines
Deal found 11/6$1,556

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Charleston to Brussels that are best for you.

Fly from

Charleston

Fly to

Brussels

Route

Depart

Return

Price

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Fri 3/27

5:30 am-8:00 am

1 stop21h 30m

Brussels Bruxelles-National

Tue 3/31

10:45 am-6:53 pm

1 stop14h 08m

$656

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Fri 3/27

8:44 pm-5:20 pm

2 stops15h 36m

Brussels Bruxelles-National

Tue 3/31

10:55 am-11:20 pm

2 stops18h 25m

$871

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Fri 3/27

4:30 pm-8:40 am

2 stops35h 10m

Brussels Bruxelles-National

Tue 3/31

10:20 am-9:20 pm

2 stops17h 00m

$1,137

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Fri 3/27

10:23 am-7:15 am

1 stop15h 52m

Brussels Bruxelles-National

Tue 3/31

10:00 am-11:54 pm

2 stops19h 54m

$1,161

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Mon 12/8

11:33 am-8:55 am

1 stop15h 22m

Brussels Bruxelles-National

Wed 12/10

11:15 am-6:12 pm

1 stop12h 57m

$1,556

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Best time to book a flight from Charleston to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Brussels

What is the cheapest time of day to fly from CHS to BRU?

Find hourly flight availability from Charleston to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

One of the essential ways to save on airfare from Charleston to Brussels is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 21% on airfare.

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated November 6, 2025.
See what other customers who have flown with United Airlines from Charleston to Brussels have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,007 reviews

Food

6.6

Crew

8.1

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,007 reviews
United Airlines
7.4
Good
9,007 reviews

Food

6.6

Crew

8.1

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Charleston to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Brussels?

    Located just 10.2 mi from the city center, Charleston is the airport most travelers will use when flying to Brussels from Charleston. Booking flights from Charleston (CHS) to Brussels should be relatively easy as there are 0 daily outbound flights to Brussels from 1 airline.

  • How long is the flight from Charleston to Brussels?

    A quick flight from Charleston to Brussels can take about 15h 36m. Delta provides one of the quickest options available for as low as $871. There are 4269 mi between Charleston and Brussels. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Charleston to Brussels round-trip?

    Flying on United Airlines is currently your cheapest option to Brussels, with prices starting at $626.

  • Can I find deals for flights from Charleston to Brussels that include hotel bookings?

    Yes. In addition to deals on Charleston to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Brussels.

  • Can I find deals for business class flights from Charleston to Brussels?

    Yes. Cheapflights offers flight deals from Charleston to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Charleston to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Charleston to Brussels

Discover the top airline that operate flights from Charleston to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$626Average$988FlexibilityNo cancel feeOn-time69%

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