$293+ Cheap flights from Cleveland (CLE) to Biloxi, MS
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — MSY
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Cleveland to BiloxiExplore the most affordable flight options available from Cleveland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Cleveland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:59 pm -
1 stop22h 06m
Mon 10/266:46 pm -
2 stops25h 08m
Deal found 9/15![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
1 stop27h 51m
Thu 10/157:45 pm -
1 stop12h 12m
Deal found 9/15![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:45 pm -
2 stops28h 20m
Sun 10/47:45 pm -
1 stop12h 22m
Deal found 9/15![Multiple Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop7h 50m
Fri 10/166:42 pm -
1 stop4h 58m
Deal found 9/14![American Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop4h 17m
Sat 10/316:26 am -
1 stop4h 37m
Deal found 9/16![Delta logo]()
$400
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:50 pm -
1 stop27h 15m
Mon 1/46:46 pm -
2 stops17h 59m
Deal found 9/16![Multiple Airlines logo]()
$426
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:05 am -
1 stop7h 02m
Sat 12/266:00 am -
1 stop4h 23m
Deal found 9/14![Delta logo]()
$438
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:06 pm -
1 stop6h 02m
Wed 9/2310:06 am -
1 stop7h 04m
Deal found 9/15![Delta logo]()
$453
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:25 pm -
1 stop7h 34m
Mon 10/126:42 pm -
1 stop4h 58m
Deal found 9/15![American Airlines logo]()
$458
Best flights from Cleveland to BiloxiDiscover carefully curated flight deals from Cleveland to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Cleveland to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:59 pm -
1 stop22h 06m
Mon 10/266:46 pm -
1 stop26h 44m
Deal found 9/15![Multiple Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:38 pm -
1 stop5h 21m
Tue 10/275:04 am -
1 stop8h 32m
Deal found 9/15![American Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:05 am -
1 stop7h 02m
Sat 12/266:00 am -
1 stop4h 23m
Deal found 9/14![Delta logo]()
$438
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/26:10 am -
1 stop8h 16m
Sat 2/61:54 pm -
1 stop6h 57m
Deal found 9/14![United Airlines logo]()
$615
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop7h 50m
Fri 10/166:42 pm -
1 stop4h 58m
Deal found 9/14![American Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop4h 17m
Mon 10/126:05 pm -
1 stop5h 52m
Deal found 9/15![Delta logo]()
$479
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:00 am -
1 stop6h 16m
Sun 11/225:49 pm -
1 stop5h 50m
Deal found 9/12![American Airlines logo]()
$477
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:25 pm -
1 stop7h 34m
Tue 10/276:41 am -
1 stop6h 08m
Deal found 9/12![American Airlines logo]()
$532
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:16 am -
1 stop5h 17m
Sat 12/266:04 pm -
1 stop5h 13m
Deal found 9/13![American Airlines logo]()
$566
Last-minute flights from Cleveland to BiloxiDiscover last-minute flight deals from Cleveland to Biloxi. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Cleveland to Biloxi. Data last updated September 17, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:06 pm -
1 stop6h 02m
Wed 9/2310:06 am -
1 stop7h 04m
Deal found 9/15![Delta logo]()
$453
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:45 pm -
2 stops28h 20m
Sun 10/47:45 pm -
1 stop12h 22m
Deal found 9/15![Multiple Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:25 pm -
1 stop7h 34m
Mon 10/126:42 pm -
1 stop4h 58m
Deal found 9/15![American Airlines logo]()
$458
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop4h 17m
Mon 10/126:05 pm -
1 stop5h 52m
Deal found 9/15![Delta logo]()
$479
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
1 stop27h 51m
Thu 10/157:45 pm -
1 stop12h 12m
Deal found 9/15![Multiple Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop7h 50m
Fri 10/166:42 pm -
1 stop4h 58m
Deal found 9/14![American Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:59 pm -
1 stop22h 06m
Mon 10/266:46 pm -
2 stops25h 08m
Deal found 9/15![Multiple Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop4h 17m
Sat 10/316:26 am -
1 stop4h 37m
Deal found 9/16![Delta logo]()
$400
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:38 pm -
1 stop5h 21m
Tue 10/271:30 pm -
2 stops7h 56m
Deal found 9/15![American Airlines logo]()
$475
Find flight deals from Cleveland to Biloxi
Keep the following information in mind while searching for Cleveland to Biloxi flight deals. Data was last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $293 (Kiwi.com) |
Popular in | September |
Cheapest in | August |
Average price | $967 |
Cheapflights Fare Finder
Customize your flight search to find flights from Cleveland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Cleveland to Biloxi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandGulfport
CLE Cleveland Hopkins Intl - GPT Gulfport Biloxi Regional
CLEGPT
Cleveland Hopkins Intl
Wed 10/21
9:59 pm-7:05 pm
1 stop22h 06m
Gulfport Biloxi Regional
Mon 10/26
6:46 pm-10:30 pm
1 stop26h 44m
$323
ClevelandGulfport
CLE Cleveland Hopkins Intl - GPT Gulfport Biloxi Regional
CLEGPT
Cleveland Hopkins Intl
Thu 10/22
7:38 pm-11:59 pm
1 stop5h 21m
Gulfport Biloxi Regional
Tue 10/27
5:04 am-2:36 pm
1 stop8h 32m
$363
ClevelandGulfport
CLE Cleveland Hopkins Intl - GPT Gulfport Biloxi Regional
CLEGPT
Cleveland Hopkins Intl
Tue 10/13
6:00 am-12:50 pm
1 stop7h 50m
Gulfport Biloxi Regional
Fri 10/16
6:42 pm-12:40 am
1 stop4h 58m
$385
ClevelandGulfport
CLE Cleveland Hopkins Intl - GPT Gulfport Biloxi Regional
CLEGPT
Cleveland Hopkins Intl
Thu 12/17
7:05 am-1:07 pm
1 stop7h 02m
Gulfport Biloxi Regional
Sat 12/26
6:00 am-11:23 am
1 stop4h 23m
$438
ClevelandGulfport
CLE Cleveland Hopkins Intl - GPT Gulfport Biloxi Regional
CLEGPT
Cleveland Hopkins Intl
Fri 11/20
5:00 am-10:16 am
1 stop6h 16m
Gulfport Biloxi Regional
Sun 11/22
5:49 pm-12:39 am
1 stop5h 50m
$477
Quickest round-trip
ClevelandGulfport
CLE Cleveland Hopkins Intl - GPT Gulfport Biloxi Regional
CLEGPT
Cleveland Hopkins Intl
Fri 10/9
6:00 am-9:17 am
1 stop4h 17m
Gulfport Biloxi Regional
Mon 10/12
6:05 pm-12:57 am
1 stop5h 52m
$479
ClevelandGulfport
CLE Cleveland Hopkins Intl - GPT Gulfport Biloxi Regional
CLEGPT
Cleveland Hopkins Intl
Sun 10/25
5:25 pm-11:59 pm
1 stop7h 34m
Gulfport Biloxi Regional
Tue 10/27
6:41 am-1:49 pm
1 stop6h 08m
$532
ClevelandGulfport
CLE Cleveland Hopkins Intl - GPT Gulfport Biloxi Regional
CLEGPT
Cleveland Hopkins Intl
Thu 12/17
8:16 am-12:33 pm
1 stop5h 17m
Gulfport Biloxi Regional
Sat 12/26
6:04 pm-12:17 am
1 stop5h 13m
$566
ClevelandGulfport
CLE Cleveland Hopkins Intl - GPT Gulfport Biloxi Regional
CLEGPT
Cleveland Hopkins Intl
Tue 2/2
6:10 am-1:26 pm
1 stop8h 16m
Gulfport Biloxi Regional
Sat 2/6
1:54 pm-9:51 pm
1 stop6h 57m
$615
Sorted by cheapest first
Best time to book a flight from Cleveland to Biloxi
Have a flexible travel schedule? Discover the best time to fly to Biloxi from Cleveland with our price prediction graph.
CLE-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Cleveland to Biloxi
CLE-B1L
CLE-GPT
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Biloxi
Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated September 17, 2026.
See what other customers who have flown with Delta and American Airlines from Cleveland to Biloxi have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Cleveland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Cleveland to Biloxi
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Complete your trip
Complete your trip to Biloxi by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Cleveland to Biloxi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Cleveland and Biloxi flights
Browse other Cleveland and Biloxi flight options. Last updated on September 17, 2026.
Other flights from Cleveland
Browse through other flights departing from Cleveland. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Cleveland to Biloxi flights
Consider these flights traveling from Cleveland to Biloxi.
Top 5 airlines flying from Cleveland to Biloxi
Discover the top 5 airlines that operate flights from Cleveland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$140 | Average$265 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$248 | Average$403 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$269 | Average$402 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$420 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$284 | Average$399 | FlexibilityNo cancel fee | On-time69% |