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Antofagasta

$25+ Cheap flights from Santiago to Antofagasta (SCL - ANF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — ANF
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno are usually found in January or March, booked 86 days in advance, depart on a Friday or Thursday and return on a Saturday

Cheap flight deals from Santiago to Antofagasta

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Antofagasta (ANF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$47
(Booking.com)

One-way from

$25
(Sky Airline)

Popular in

July

Cheapest in

January

Average price

$65

Good round-trip deal

$49 or less
From Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno
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One-way flight from Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno
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Highest demand for flights based on searches. 7% potential increase in price ($4 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($2 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno.
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Find flight deals from Santiago to Antofagasta

Cheapest flights from Santiago to Antofagasta
Explore the most affordable flight options available from Santiago to Antofagasta. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:26 amSCL - ANF
Nonstop2h 04mJetSMART
Mon 10/208:34 amANF - SCL
Nonstop1h 52mJetSMART
Deal found 9/10$47
This Sky Airline deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/264:00 amSCL - ANF
Nonstop2h 01mSky Airline
Mon 9/292:34 pmANF - SCL
Nonstop1h 56mSky Airline
Deal found 9/10$49
This Sky Airline deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/204:00 amSCL - ANF
Nonstop2h 07mSky Airline
Sat 11/229:20 pmANF - SCL
Nonstop1h 59mSky Airline
Deal found 9/10$50
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3012:13 pmSCL - ANF
Nonstop2h 09mLATAM Airlines
Sun 11/211:10 pmANF - SCL
Nonstop1h 52mLATAM Airlines
Deal found 9/10$53
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/55:42 amSCL - ANF
Nonstop2h 01mMultiple Airlines
Sat 10/118:58 pmANF - SCL
Nonstop1h 52mMultiple Airlines
Deal found 9/10$63
This Booking.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/265:36 amSCL - ANF
Nonstop2h 04mJetSMART
Sun 11/28:32 amANF - SCL
Nonstop1h 54mJetSMART
Deal found 9/11$64
This Sky Airline deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/134:00 amSCL - ANF
Nonstop2h 07mSky Airline
Wed 11/197:11 pmANF - SCL
1 stop3h 09mSky Airline
Deal found 9/10$68
This CheapOair deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/308:51 pmSCL - ANF
Nonstop2h 04mJetSMART
Sun 11/28:32 amANF - SCL
Nonstop1h 54mJetSMART
Deal found 9/11$71
This Sky Airline deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:51 amSCL - ANF
Nonstop2h 01mSky Airline
Fri 10/247:01 amANF - SCL
Nonstop1h 56mSky Airline
Deal found 9/9$73
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/54:39 amSCL - ANF
Nonstop2h 10mLATAM Airlines
Mon 10/139:52 amANF - SCL
Nonstop1h 53mLATAM Airlines
Deal found 9/10$77

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Antofagasta that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Santiago to Antofagasta that are best for you.

Fly from

Santiago

Fly to

Antofagasta

Route

Depart

Return

Price

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Wed 10/8

11:41 am-2:52 pm

1 stop3h 11m

Antofagasta Cerro Moreno

Tue 10/14

9:43 pm-11:39 pm

Nonstop1h 56m

$49

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Thu 10/9

9:04 pm-11:05 pm

Nonstop2h 01m

Antofagasta Cerro Moreno

Sat 10/11

9:02 pm-10:58 pm

Nonstop1h 56m

$49

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Sat 10/4

6:51 am-8:52 am

Nonstop2h 01m

Antofagasta Cerro Moreno

Sat 10/11

9:02 pm-10:58 pm

Nonstop1h 56m

$49

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Fri 10/24

4:15 am-6:16 am

Nonstop2h 01m

Antofagasta Cerro Moreno

Sun 10/26

10:25 pm-12:24 am

Nonstop1h 59m

$49

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Fri 10/17

4:45 pm-6:46 pm

Nonstop2h 01m

Antofagasta Cerro Moreno

Sun 10/19

10:19 pm-12:15 am

Nonstop1h 56m

$49

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Sat 10/18

6:51 am-8:52 am

Nonstop2h 01m

Antofagasta Cerro Moreno

Sun 10/19

10:19 pm-12:15 am

Nonstop1h 56m

$49

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Sat 9/27

8:35 am-10:36 am

Nonstop2h 01m

Antofagasta Cerro Moreno

Sun 10/5

9:06 pm-11:02 pm

Nonstop1h 56m

$49

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Sat 10/4

6:51 am-8:52 am

Nonstop2h 01m

Antofagasta Cerro Moreno

Sun 10/5

8:18 am-10:14 am

Nonstop1h 56m

$49

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Fri 10/10

4:15 am-6:16 am

Nonstop2h 01m

Antofagasta Cerro Moreno

Sun 10/12

9:02 pm-10:58 pm

Nonstop1h 56m

$49

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Fri 9/26

4:00 am-6:01 am

Nonstop2h 01m

Antofagasta Cerro Moreno

Mon 9/29

2:34 pm-4:30 pm

Nonstop1h 56m

$49

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 19 results
1
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Best time to book a flight from Santiago to Antofagasta

Have a flexible travel schedule? Discover the best time to fly to Antofagasta from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Antofagasta

How far ahead should I book a flight from Santiago to Antofagasta?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Antofagasta. Price data was last updated on August 29, 2025.

Booking 86 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Antofagasta. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest time of day to fly from SCL to ANF?

Find hourly flight availability from Santiago to Antofagasta. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Santiago to Antofagasta at noon. Doing so could potentially save you 60% on the flight price compared to flying in the evening, which is usually more expensive.

How much does it cost to fly round-trip from Santiago to Antofagasta?

Reviews of airlines servicing Antofagasta

Get insights into the airlines that provide service to Antofagasta. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Antofagasta. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Santiago to Antofagasta, such as LATAM Airlines and JetSMART. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,847 reviews

Boarding

7.6

Crew

8.0

Entertainment

7.0

Overall

7.5

Comfort

7.4

Food

6.7

Reviews

1 / 20
8.0
Excellent

Darrel,Sep 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.
LATAM Airlines
7.5
Good
1,847 reviews
LATAM Airlines
7.5
Good
1,847 reviews

Boarding

7.6

Crew

8.0

Entertainment

7.0

Overall

7.5

Comfort

7.4

Food

6.7

Reviews

1 / 20
8.0
Excellent

Darrel,Sep 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.
JetSMART
6.5
Okay
225 reviews
LATAM Airlines
7.5
Good
1,847 reviews

Boarding

7.6

Crew

8.0

Entertainment

7.0

Overall

7.5

Comfort

7.4

Food

6.7

Reviews

1 / 20
8.0
Excellent

Darrel,Sep 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Antofagasta. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Santiago to Antofagasta?

    Booking a flight from Santiago Arturo Merino Benitez (SCL) to Antofagasta Cerro Moreno (ANF) is your only option if you wish to fly from Santiago to Antofagasta. On a typical day, there are 5 flights from Arturo Merino Benitez to Cerro Moreno, all of which are around 2h 01m for a nonstop flight. You can also purchase a plane ticket from 3 airlines when you book a flight from Arturo Merino Benitez to Antofagasta.

  • How long is the flight from Santiago to Antofagasta?

    A quick flight from Santiago to Antofagasta can take about 3h 11m. Sky Airline provides one of the quickest options available for as low as $49. Airlines will cover a distance of 687 mi.

  • What are the cheapest airlines flying from Santiago to Antofagasta round-trip?

    Currently priced at $44, JetSMART will fly you from Santiago to Antofagasta and back. In addition to JetSMART, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Sky Airline and LATAM Airlines - these airlines can fly you to your destination from $59 and $69, respectively. JetSMART is 29% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the most reliable airlines from Santiago to Antofagasta?

    Consider Iberia (94%), Delta (94%) or LATAM Airlines (84%) when booking your flight. These represent the most reliable airlines when flying from Santiago to Antofagasta.

  • What are the cheapest flights from Santiago to Antofagasta?

    Looking at all options, your cheapest flight can be booked for $44. While the most popular route (Santiago Arturo Merino Benitez - Antofagasta Cerro Moreno) can be booked for $47 on average, our data indicates $186 when flying from Santiago to Antofagasta.

  • Can I find deals for flights from Santiago to Antofagasta that include hotel bookings?

    Yes. In addition to deals on Santiago to Antofagasta flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Antofagasta?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Antofagasta.

  • Can I find deals for business class flights from Santiago to Antofagasta?

    Yes. Cheapflights offers flight deals from Santiago to Antofagasta by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 3 airlines flying from Santiago to Antofagasta

Discover the top 3 airlines that operate flights from Santiago to Antofagasta. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetSMARTCheapest$44Average$50FlexibilityNo cancel feeOn-timeN/A
Sky AirlineCheapest$59Average$100FlexibilityNo cancel feeOn-time73%
LATAM AirlinesCheapest$69Average$136FlexibilityNo cancel feeOn-time81%

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