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Antofagasta

$45+ Cheap flights from Santiago to Antofagasta (SCL - ANF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — ANF
Mar 11 — Mar 181
Wed 3/11
Wed 3/18
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno are usually found in June or March, booked 90 days in advance, depart on a Thursday or Saturday and return on a Tuesday

Cheap flight deals from Santiago to Antofagasta

Cheapest flights from Santiago to Antofagasta
Explore the most affordable flight options available from Santiago to Antofagasta. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.

This FlightHub deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/203:30 pm
SCL
-
ANF
Nonstop2h 04m
JetSMART
Sun 3/2211:59 pm
ANF
-
SCL
Nonstop1h 54m
JetSMART
Deal found 2/9$68
This Booking.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:35 pm
SCL
-
ANF
Nonstop2h 05m
Multiple Airlines
Wed 7/13:41 pm
ANF
-
SCL
1 stop3h 09m
Multiple Airlines
Deal found 2/8$69
This JetSMART deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/295:14 am
SCL
-
ANF
Nonstop2h 04m
JetSMART
Sat 4/113:06 pm
ANF
-
SCL
Nonstop1h 57m
JetSMART
Deal found 2/7$73
This Booking.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:04 am
SCL
-
ANF
Nonstop2h 01m
Multiple Airlines
Mon 3/169:49 pm
ANF
-
SCL
Nonstop1h 52m
Multiple Airlines
Deal found 2/8$75
This Booking.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:00 am
SCL
-
ANF
Nonstop2h 04m
Multiple Airlines
Fri 3/137:13 am
ANF
-
SCL
Nonstop1h 51m
Multiple Airlines
Deal found 2/6$79
This Sky Airline deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:17 am
SCL
-
ANF
1 stop3h 13m
Sky Airline
Wed 4/221:08 pm
ANF
-
SCL
Nonstop1h 51m
Sky Airline
Deal found 2/9$80
This JetSMART deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:04 am
SCL
-
ANF
Nonstop2h 04m
JetSMART
Mon 4/68:53 am
ANF
-
SCL
Nonstop1h 54m
JetSMART
Deal found 2/5$83
This JetSMART deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:06 am
SCL
-
ANF
Nonstop2h 04m
JetSMART
Tue 3/178:56 pm
ANF
-
SCL
Nonstop1h 54m
JetSMART
Deal found 2/9$85
This JetSMART deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:04 am
SCL
-
ANF
Nonstop2h 04m
JetSMART
Sat 4/113:06 pm
ANF
-
SCL
Nonstop1h 57m
JetSMART
Deal found 2/6$88
This JetSMART deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:06 am
SCL
-
ANF
Nonstop2h 04m
JetSMART
Mon 3/167:06 am
ANF
-
SCL
Nonstop1h 54m
JetSMART
Deal found 2/9$89
This JetSMART deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:52 pm
SCL
-
ANF
1 stop19h 57m
JetSMART
Sun 3/2210:19 pm
ANF
-
SCL
1 stop19h 51m
JetSMART
Deal found 2/9$96
This FlightHub deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:49 am
SCL
-
ANF
Nonstop2h 01m
Sky Airline
Mon 2/239:15 pm
ANF
-
SCL
Nonstop2h 01m
Sky Airline
Deal found 2/6$97

Find flight deals from Santiago to Antofagasta

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Antofagasta (ANF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$68
(FlightHub)

One-way from

$45
(Super.com)

Popular in

January

Cheapest in

June

Average price

$95

Good round-trip deal

$117 or less

Good one-way deal

$65 or less
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Antofagasta Cerro Moreno flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Antofagasta Cerro Moreno flights.
Search Deals
From Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($2 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a round-trip flight from Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno.
Search Deals
Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Antofagasta that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Santiago to Antofagasta that are best for you.

Fly from

Santiago

Fly to

Antofagasta

Route

Depart

Return

Price

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Wed 3/25

7:58 am-10:02 am

Nonstop2h 04m

Antofagasta Cerro Moreno

Wed 4/1

11:17 pm-1:11 am

Nonstop1h 54m

$69

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Tue 6/30

12:35 pm-2:40 pm

Nonstop2h 05m

Antofagasta Cerro Moreno

Wed 7/1

9:26 pm-11:21 pm

Nonstop1h 55m

$69

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Sat 3/7

6:06 am-8:10 am

Nonstop2h 04m

Antofagasta Cerro Moreno

Sat 3/14

8:56 pm-10:50 pm

Nonstop1h 54m

$69

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Thu 4/2

6:06 am-8:10 am

Nonstop2h 04m

Antofagasta Cerro Moreno

Sun 4/5

10:52 pm-12:46 am

Nonstop1h 54m

$69

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Sun 3/29

5:14 am-7:18 am

Nonstop2h 04m

Antofagasta Cerro Moreno

Thu 4/9

7:35 am-9:32 am

Nonstop1h 57m

$73

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Sun 3/29

5:14 am-7:18 am

Nonstop2h 04m

Antofagasta Cerro Moreno

Mon 4/13

8:53 pm-10:50 pm

Nonstop1h 57m

$73

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Sun 3/29

5:14 am-7:18 am

Nonstop2h 04m

Antofagasta Cerro Moreno

Sun 4/12

11:17 pm-1:14 am

Nonstop1h 57m

$73

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Sun 3/29

5:14 am-7:18 am

Nonstop2h 04m

Antofagasta Cerro Moreno

Fri 4/10

8:39 pm-10:36 pm

Nonstop1h 57m

$73

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Mon 3/9

7:04 am-9:05 am

Nonstop2h 01m

Antofagasta Cerro Moreno

Mon 3/16

9:49 pm-11:41 pm

Nonstop1h 52m

$75

SantiagoAntofagasta

SCL - ANF

SCLANF

Santiago Arturo Merino Benitez

Fri 3/6

5:00 am-7:04 am

Nonstop2h 04m

Antofagasta Cerro Moreno

Fri 3/13

7:13 am-9:04 am

Nonstop1h 51m

$79

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/6

Showing 1-10 of 22 results
1
2
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  • Most accurate provider: When it comes to deals on Santiago-Antofagasta flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Antofagasta flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Antofagasta flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Antofagasta flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Antofagasta flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Antofagasta

Have a flexible travel schedule? Discover the best time to fly to Antofagasta from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Antofagasta

How far ahead should I book a flight from Santiago to Antofagasta?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Antofagasta. Price data was last updated on February 6, 2026.

Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Antofagasta. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Antofagasta?

Currently, June is the cheapest month in which you can book a flight from Santiago to Antofagasta (average of $19). Flying from Santiago to Antofagasta in February is currently the most expensive (average of $37). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to ANF?

Find hourly flight availability from Santiago to Antofagasta. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 9, 2026.

It’s typically best to fly out from Santiago to Antofagasta at noon. Doing so could potentially save you 47% on the flight price compared to flying in the evening, which is usually more expensive.

How much does it cost to fly round-trip from Santiago to Antofagasta?

Reviews of airlines servicing Antofagasta

Get insights into the airlines that provide service to Antofagasta. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Antofagasta. Reviews last updated February 9, 2026.
Read through reviews of airlines operating flights from Santiago to Antofagasta, such as LATAM Airlines and JetSMART. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,919 reviews

Boarding

7.5

Food

6.7

Crew

8.0

Comfort

7.3

Entertainment

7.0

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
LATAM Airlines
7.5
Good
1,919 reviews
LATAM Airlines
7.5
Good
1,919 reviews

Boarding

7.5

Food

6.7

Crew

8.0

Comfort

7.3

Entertainment

7.0

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
JetSMART
6.7
Okay
268 reviews
LATAM Airlines
7.5
Good
1,919 reviews

Boarding

7.5

Food

6.7

Crew

8.0

Comfort

7.3

Entertainment

7.0

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken

Related info for your journey

Find useful and relevant information for your journey from Santiago to Antofagasta. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Santiago to Antofagasta?

    Booking a flight from Santiago Arturo Merino Benitez (SCL) to Antofagasta Cerro Moreno (ANF) is your only option if you wish to fly from Santiago to Antofagasta. On a typical day, there are 8 flights from Arturo Merino Benitez to Cerro Moreno, all of which are around 1h 59m for a nonstop flight. You can also purchase a plane ticket from 3 airlines when you book a flight from Arturo Merino Benitez to Antofagasta.

  • How long is the flight from Santiago to Antofagasta?

    A quick flight from Santiago to Antofagasta can take about 2h 04m. JetSMART provides one of the quickest options available for as low as $68. Airlines will cover a distance of 687 mi. All flights are typically nonstop.

  • What are the cheapest airlines flying from Santiago to Antofagasta round-trip?

    Currently priced at $44, JetSMART will fly you from Santiago to Antofagasta and back. In addition to JetSMART, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Sky Airline and LATAM Airlines - these airlines can fly you to your destination from $53 and $75, respectively. JetSMART is 43% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Santiago to Antofagasta one-way?

    To fly one-way, consider booking your trip with Sky Airline, which is currently one of the cheapest options available, starting at $13. JetSMART flights start at $20 while deals on LATAM Airlines start at $41 one-way.

  • What are the most reliable airlines from Santiago to Antofagasta?

    Consider Iberia (89%), Sky Airline (86%) or LATAM Airlines (86%) when booking your flight. These represent the most reliable airlines when flying from Santiago to Antofagasta.

  • What are the cheapest flights from Santiago to Antofagasta?

    Looking at all options, your cheapest flight can be booked for $65. While the most popular route (Santiago Arturo Merino Benitez - Antofagasta Cerro Moreno) can be booked for $108 on average, our data indicates $108 when flying from Santiago to Antofagasta.

  • Can I find deals for flights from Santiago to Antofagasta that include hotel bookings?

    Yes. In addition to deals on Santiago to Antofagasta flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Antofagasta?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Antofagasta.

  • Can I find deals for business class flights from Santiago to Antofagasta?

    Yes. Cheapflights offers flight deals from Santiago to Antofagasta by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Antofagasta?

    Currently, June is the cheapest month in which you can book a flight from Santiago to Antofagasta (average of $19). Flying from Santiago to Antofagasta in February is currently the most expensive (average of $37). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Santiago to Antofagasta

Discover the top 3 airlines that operate flights from Santiago to Antofagasta. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetSMARTCheapest$44Average$50FlexibilityNo cancel feeOn-timeN/A
Sky AirlineCheapest$53Average$94FlexibilityNo cancel feeOn-time73%
LATAM AirlinesCheapest$75Average$136FlexibilityNo cancel feeOn-time81%

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