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Florence

$160+ Cheap flights from Florence, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — MCO
Aug 2 — Aug 91
Sat 8/2
Sat 8/9
1 adult, Economy
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What to know about flights from Florence

Discover essential information about flights departing from Florence, including flight schedules, destinations, airlines operating at the Florence airport, and any specific guidelines or requirements for travelers. Please note that the information is based on the most recent updates available. Data last updated July 28, 2025.

Cheapest one-way flight

$257

Cheapest round-trip flight

$406

Cheapest airline

American Airlines

Most popular destination

Charlotte Douglas (CLT)

Good round-trip deal

$430 or less

Good one-way deal

$298 or less
The cheapest one-way flight from Florence is currently to Charlotte Douglas.
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The cheapest round-trip flight from Florence is currently to Charlotte Douglas.
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On average, American Airlines currently has the cheapest one-way flight from Florence (avg. price of $372).
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Charlotte Douglas (CLT) is currently the most popular flight destination from Florence (average round-trip price of $366).
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Price to beat on a round-trip flight from Florence.
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Price to beat on a one-way flight from Florence.
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Find flights from Florence

Cheapest flights from Florence
Explore the most affordable flight options available from Florence. Find the lowest fares based on data from user searches, with prices last updated on July 28, 2025.

Tue 8/2612:11 pmFLO - BNA
1 stop3h 16mAmerican Airlines
Tue 9/26:53 amBNA - FLO
1 stop3h 53mAmerican Airlines
Deal found 7/26$319
Sat 9/66:14 amFLO - MCO
2 stops13h 30mAmerican Airlines
Sat 9/1312:11 pmMCO - FLO
2 stops11h 05mAmerican Airlines
Deal found 7/27$336
Tue 9/235:37 pmFLO - EWR
1 stop4h 23mAmerican Airlines
Sun 9/287:35 pmEWR - FLO
1 stop4h 38mAmerican Airlines
Deal found 7/28$340
Wed 9/36:14 amFLO - SFO
1 stop8h 16mAmerican Airlines
Sat 9/612:38 pmSFO - FLO
1 stop7h 38mAmerican Airlines
Deal found 7/26$387
Wed 8/2012:11 pmFLO - IAH
1 stop4h 27mAmerican Airlines
Wed 9/311:00 amIAH - FLO
1 stop5h 12mAmerican Airlines
Deal found 7/27$414
Tue 8/1212:11 pmFLO - DFW
1 stop6h 59mAmerican Airlines
Sat 8/163:40 pmDFW - FLO
1 stop7h 19mAmerican Airlines
Deal found 7/28$415
Wed 8/206:20 amFLO - HOU
2 stops8h 31mAmerican Airlines
Wed 9/32:33 pmHOU - FLO
2 stops7h 43mAmerican Airlines
Deal found 7/27$424
Tue 8/123:30 pmFLO - BOS
1 stop4h 26mAmerican Airlines
Sat 8/165:54 amBOS - FLO
1 stop4h 56mAmerican Airlines
Deal found 7/27$429
Sun 11/236:33 pmFLO - FLL
1 stop5h 50mAmerican Airlines
Sun 12/215:35 pmFLL - FLO
1 stop6h 01mAmerican Airlines
Deal found 7/27$455
Tue 9/96:14 amFLO - FCO
2 stops18h 51mAmerican Airlines
Tue 9/1612:10 pmFCO - FLO
1 stop17h 06mAmerican Airlines
Deal found 7/27$770

Find flights from Florence within your budget

 
Find flights departing from Florence that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on July 28, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches

Fly to

Orlando

Route

Depart

Return

Price

FlorenceNashville

FLO - BNA

FLOBNA

Florence

Tue 8/26

12:11 pm-2:27 pm

1 stop3h 16m

Nashville Intl

Tue 9/2

6:53 am-11:46 am

1 stop3h 53m

$319

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Sat 9/6

6:14 am-7:44 pm

2 stops13h 30m

Orlando

Sat 9/13

12:11 pm-11:16 pm

2 stops11h 05m

$336

FlorenceNewark

FLO - EWR

FLOEWR

Florence

Tue 9/23

5:37 pm-10:00 pm

1 stop4h 23m

Newark

Sun 9/28

7:35 pm-12:13 am

1 stop4h 38m

$340

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 9/3

6:14 am-11:30 am

1 stop8h 16m

San Francisco

Sat 9/6

12:38 pm-11:16 pm

1 stop7h 38m

$387

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Wed 8/20

12:11 pm-3:38 pm

1 stop4h 27m

Houston George Bush Intcntl

Wed 9/3

11:00 am-5:12 pm

1 stop5h 12m

$414

FlorenceDallas

FLO - DFW

FLODFW

Florence

Tue 8/12

12:11 pm-6:10 pm

1 stop6h 59m

Dallas/Fort Worth

Sat 8/16

3:40 pm-11:59 pm

1 stop7h 19m

$415

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Wed 8/20

6:20 am-1:51 pm

2 stops8h 31m

Houston Hobby

Wed 9/3

2:33 pm-11:16 pm

2 stops7h 43m

$424

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Tue 8/12

3:30 pm-7:56 pm

1 stop4h 26m

Boston Logan Intl

Sat 8/16

5:54 am-10:50 am

1 stop4h 56m

$429

FlorenceFort Lauderdale

FLO - FLL

FLOFLL

Florence

Mon 8/11

3:30 pm-8:22 pm

1 stop4h 52m

Fort Lauderdale

Fri 8/15

9:07 am-3:04 pm

1 stop5h 57m

$733

FlorenceRome

FLO - FCO

FLOFCO

Florence

Tue 9/9

6:14 am-7:05 am

2 stops18h 51m

Rome Fiumicino

Tue 9/16

12:10 pm-11:16 pm

1 stop17h 06m

$770

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 16 results
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Best time to book a flight from Florence

Have a flexible travel schedule? Discover the best time to fly from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Florence

Get recent, data-driven insights about flights from Florence including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Florence, South Carolina?

Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina (average of $46). Flying from Florence, South Carolina in May will prove the most costly (average of $79). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

What is the cheapest place to fly to from Florence, South Carolina?

The cheapest city to fly to from Florence, South Carolina is Charlotte Douglas, with prices starting at $257. Explore other affordable destinations below.

Charlotte Douglas
Charlotte Douglas
From $257

Airline reviews for flights from Florence

Read reviews and ratings of airlines operating flights from Florence. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Florence travel. Please note that the reviews are sourced from user searches and were last updated on July 28, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches.
Get a feel of what it's like to fly with American Airlines from Florence by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Comfort

7.2

Overall

7.2

Boarding

7.5

Food

6.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Comfort

7.2

Overall

7.2

Boarding

7.5

Food

6.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

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Related info for your journey

Access useful and relevant information related to your journey from Florence. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated July 28, 2025.

  • What are the most popular destinations to fly to from Florence, South Carolina?

    This month, the top selected destinations from Florence, South Carolina are Nashville, Las Vegas, New York. Throughout the year, Las Vegas, New York, Nashville are some of the top choices made by users flying from Florence, South Carolina.

  • What is the cheapest flight from Florence, South Carolina to anywhere?

    Users have flown out of Florence, South Carolina for as low as $257 to Charlotte (prices may vary depending on the airline and departure time). On average, users have booked flights for $437 to fly from Florence, South Carolina.

  • What is the cheapest month to fly from Florence, South Carolina?

    September is currently the cheapest month to fly from Florence, South Carolina. At this moment in time May is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

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