$148+ Cheap flights from San Diego (SAN) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — EYW
Jul 10 — Jul 171
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Florida Keys with Cheapflights
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Cheapest flights from San Diego to Florida KeysExplore the most affordable flight options available from San Diego to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
Explore the most affordable flight options available from San Diego to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2912:32 pm
SAN
- MIA
Nonstop5h 22m
American Airlines
Wed 9/98:10 pm
MIA
- SAN
Nonstop5h 15m
American Airlines
Deal found 6/9![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:30 pm
SAN
- EYW
1 stop12h 00m
United Airlines
Wed 7/294:00 pm
EYW
- SAN
1 stop9h 34m
United Airlines
Deal found 6/5![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:45 pm
SAN
- MIA
Nonstop5h 08m
American Airlines
Tue 9/87:40 pm
MIA
- SAN
Nonstop5h 20m
American Airlines
Deal found 6/10![American Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:40 am
SAN
- MIA
2 stops11h 15m
Southwest
Tue 8/116:45 am
MIA
- SAN
2 stops9h 15m
Southwest
Deal found 6/9![Southwest logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3012:09 pm
SAN
- MIA
1 stop19h 07m
Multiple Airlines
Mon 9/147:20 am
MIA
- SAN
2 stops14h 09m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$382
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:40 am
SAN
- MIA
2 stops10h 00m
Southwest
Tue 8/116:45 am
MIA
- SAN
2 stops9h 15m
Southwest
Deal found 6/10![Southwest logo]()
$383
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:15 am
SAN
- MIA
1 stop12h 00m
Southwest
Tue 7/213:05 pm
MIA
- SAN
1 stop8h 05m
Southwest
Deal found 6/8![Southwest logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:37 am
SAN
- MIA
2 stops24h 53m
Frontier
Thu 9/107:20 am
MIA
- SAN
1 stop11h 21m
Frontier
Deal found 6/8![Frontier logo]()
$385
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:45 pm
SAN
- MIA
Nonstop5h 03m
American Airlines
Sat 10/38:10 pm
MIA
- SAN
Nonstop5h 15m
American Airlines
Deal found 6/7![American Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:25 pm
SAN
- MIA
Nonstop5h 11m
American Airlines
Tue 7/217:30 pm
MIA
- SAN
1 stop7h 29m
American Airlines
Deal found 6/7![American Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2912:32 pm
SAN
- MIA
Nonstop5h 22m
American Airlines
Tue 9/87:40 pm
MIA
- SAN
Nonstop5h 20m
American Airlines
Deal found 6/10![American Airlines logo]()
$389
This Expedia deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:00 am
SAN
- MIA
1 stop16h 51m
Frontier
Sun 7/196:00 am
MIA
- SAN
1 stop30h 05m
Frontier
Deal found 6/9![Frontier logo]()
$390
Best flights from San Diego to Florida KeysDiscover carefully curated flight deals from San Diego to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
Discover carefully curated flight deals from San Diego to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:15 am
SAN
- MIA
1 stop8h 35m
Delta
Tue 7/147:17 pm
MIA
- SAN
1 stop7h 25m
Delta
Deal found 6/8![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/57:45 am
SAN
- MIA
2 stops11h 40m
Southwest
Wed 7/84:30 pm
MIA
- SAN
1 stop8h 30m
Southwest
Deal found 6/6![Southwest logo]()
$453
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:45 am
SAN
- MIA
2 stops10h 49m
United Airlines
Wed 9/93:57 pm
MIA
- SAN
1 stop9h 13m
United Airlines
Deal found 6/5![United Airlines logo]()
$497
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:20 am
SAN
- EYW
2 stops9h 46m
American Airlines
Wed 7/1511:28 am
EYW
- SAN
2 stops11h 35m
American Airlines
Deal found 6/8![American Airlines logo]()
$673
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:30 pm
SAN
- EYW
1 stop9h 30m
Delta
Wed 7/296:18 pm
EYW
- SAN
1 stop7h 39m
Delta
Deal found 6/6![Delta logo]()
$442
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:40 pm
SAN
- MIA
2 stops11h 55m
Southwest
Mon 8/316:20 am
MIA
- SAN
2 stops13h 20m
Southwest
Deal found 6/6![Southwest logo]()
$465
This Gotogate deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/912:09 pm
SAN
- EYW
3 stops45h 25m
Breeze Airways
Fri 8/141:11 pm
EYW
- SAN
2 stops49h 13m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$1,029
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3010:40 am
SAN
- MIA
2 stops9h 00m
Southwest
Sun 8/25:35 am
MIA
- SAN
1 stop6h 55m
Southwest
Deal found 6/8![Southwest logo]()
$490
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3111:55 am
SAN
- MIA
2 stops9h 35m
Southwest
Mon 8/35:25 am
MIA
- SAN
2 stops8h 30m
Southwest
Deal found 6/8![Southwest logo]()
$495
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:40 pm
SAN
- MIA
2 stops12h 45m
Southwest
Thu 6/255:00 pm
MIA
- SAN
2 stops9h 25m
Southwest
Deal found 6/6![Southwest logo]()
$500
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/98:00 am
SAN
- MIA
2 stops11h 50m
Southwest
Wed 8/122:25 pm
MIA
- SAN
2 stops9h 40m
Southwest
Deal found 6/5![Southwest logo]()
$502
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:20 am
SAN
- EYW
2 stops9h 46m
American Airlines
Wed 7/294:41 pm
EYW
- SAN
2 stops10h 18m
American Airlines
Deal found 6/5![American Airlines logo]()
$749
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:40 am
SAN
- MIA
1 stop8h 50m
Southwest
Wed 7/16:35 am
MIA
- SAN
2 stops10h 40m
Southwest
Deal found 6/5![Southwest logo]()
$513
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/910:45 pm
SAN
- EYW
1 stop7h 59m
American Airlines
Fri 8/141:50 pm
EYW
- SAN
1 stop8h 54m
American Airlines
Deal found 6/9![American Airlines logo]()
$789
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:30 am
SAN
- MIA
1 stop9h 10m
Southwest
Sun 8/96:45 am
MIA
- SAN
2 stops10h 20m
Southwest
Deal found 6/9![Southwest logo]()
$525
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:00 pm
SAN
- EYW
1 stop22h 19m
United Airlines
Thu 7/92:26 pm
EYW
- SAN
1 stop12h 14m
United Airlines
Deal found 6/9![United Airlines logo]()
$1,639
Last-minute flights from San Diego to Florida KeysDiscover last-minute flight deals from San Diego to Florida Keys. Data last updated June 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Florida Keys. Data last updated June 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/232:31 pm
SAN
- MIA
1 stop7h 20m
Delta
Tue 6/307:00 pm
MIA
- SAN
1 stop7h 40m
Delta
Deal found 6/8![Delta logo]()
$383
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:15 am
SAN
- MIA
1 stop8h 35m
Delta
Fri 7/177:17 pm
MIA
- SAN
1 stop7h 25m
Delta
Deal found 6/9![Delta logo]()
$385
This Expedia deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:35 pm
SAN
- MIA
1 stop17h 42m
Multiple Airlines
Tue 7/216:00 am
MIA
- SAN
1 stop30h 05m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$386
This Gotogate deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1110:00 am
SAN
- MIA
1 stop16h 17m
Frontier
Sat 7/186:00 am
MIA
- SAN
1 stop30h 05m
Frontier
Deal found 6/8![Frontier logo]()
$388
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:15 am
SAN
- MIA
1 stop12h 00m
Southwest
Tue 7/213:05 pm
MIA
- SAN
1 stop8h 05m
Southwest
Deal found 6/8![Southwest logo]()
$384
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:25 pm
SAN
- MIA
Nonstop5h 11m
American Airlines
Tue 7/217:30 pm
MIA
- SAN
1 stop7h 29m
American Airlines
Deal found 6/7![American Airlines logo]()
$387
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:25 am
SAN
- MIA
1 stop20h 26m
Frontier
Sun 7/196:00 am
MIA
- SAN
1 stop30h 05m
Frontier
Deal found 6/10![Frontier logo]()
$380
This Expedia deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:00 am
SAN
- MIA
1 stop16h 51m
Frontier
Sun 7/196:00 am
MIA
- SAN
1 stop30h 05m
Frontier
Deal found 6/9![Frontier logo]()
$390
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:30 pm
SAN
- EYW
1 stop12h 00m
United Airlines
Wed 7/294:00 pm
EYW
- SAN
1 stop9h 34m
United Airlines
Deal found 6/5![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:40 am
SAN
- MIA
2 stops11h 15m
Southwest
Tue 8/116:45 am
MIA
- SAN
2 stops9h 15m
Southwest
Deal found 6/9![Southwest logo]()
$381
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:00 am
SAN
- MIA
1 stop9h 35m
American Airlines
Sat 8/18:50 am
MIA
- SAN
Nonstop5h 22m
American Airlines
Deal found 6/9![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:25 pm
SAN
- MIA
Nonstop5h 11m
American Airlines
Tue 8/48:12 pm
MIA
- SAN
Nonstop5h 26m
American Airlines
Deal found 6/8![American Airlines logo]()
$379
One-way flights from San Diego to Florida KeysSearch for one-way flight options from San Diego to Florida Keys. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
Search for one-way flight options from San Diego to Florida Keys. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:40 pm
SAN
- MIA
2 stops12h 45m
Southwest
Deal found 6/5![Southwest logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:53 pm
SAN
- MIA
2 stops23h 23m
Frontier
Deal found 6/6![Frontier logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:25 am
SAN
- MIA
2 stops38h 51m
Frontier
Deal found 6/10![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/98:51 pm
SAN
- MIA
1 stop30h 39m
Frontier
Deal found 6/9![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/214:12 pm
SAN
- MIA
2 stops10h 39m
Frontier
Deal found 6/7![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:09 pm
SAN
- MIA
1 stop29h 16m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$158
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:00 pm
SAN
- MIA
1 stop8h 07m
Delta
Deal found 6/10![Delta logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:12 pm
SAN
- MIA
2 stops10h 39m
Frontier
Deal found 6/8![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:35 am
SAN
- MIA
1 stop28h 37m
Frontier
Deal found 6/7![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:12 pm
SAN
- MIA
2 stops29h 19m
Frontier
Deal found 6/7![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:12 pm
SAN
- EYW
3 stops21h 08m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:03 pm
SAN
- EYW
2 stops17h 22m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$232
Find flight deals from San Diego to Florida Keys
Keep the following information in mind while searching for San Diego to Florida Keys flight deals. Data was last updated June 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $379 (American Airlines) |
One-way from | $148 (Southwest) |
Popular in | December |
Cheapest in | October |
Average price | $536 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from San Diego to Florida Keys that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Tue 6/30
6:15 am-5:50 pm
1 stop8h 35m
Miami
Tue 7/14
7:17 pm-11:42 pm
1 stop7h 25m
$399
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Mon 7/20
10:30 pm-11:00 am
1 stop9h 30m
Key West
Wed 7/29
6:18 pm-10:57 pm
1 stop7h 39m
$442
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sun 7/5
7:45 am-10:25 pm
2 stops11h 40m
Miami
Wed 7/8
4:30 pm-10:00 pm
1 stop8h 30m
$453
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Fri 8/28
10:40 pm-1:35 pm
2 stops11h 55m
Miami
Mon 8/31
6:20 am-4:40 pm
2 stops13h 20m
$465
Quickest round-trip
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Thu 7/30
10:40 am-10:40 pm
2 stops9h 00m
Miami
Sun 8/2
5:35 am-9:30 am
1 stop6h 55m
$490
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Fri 7/31
11:55 am-12:30 am
2 stops9h 35m
Miami
Mon 8/3
5:25 am-10:55 am
2 stops8h 30m
$495
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 8/29
8:45 am-10:34 pm
2 stops10h 49m
Miami
Wed 9/9
3:57 pm-10:10 pm
1 stop9h 13m
$497
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Tue 6/23
10:40 pm-2:25 pm
2 stops12h 45m
Miami
Thu 6/25
5:00 pm-11:25 pm
2 stops9h 25m
$500
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sun 8/9
8:00 am-10:50 pm
2 stops11h 50m
Miami
Wed 8/12
2:25 pm-9:05 pm
2 stops9h 40m
$502
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sun 6/28
6:40 am-6:30 pm
1 stop8h 50m
Miami
Wed 7/1
6:35 am-2:15 pm
2 stops10h 40m
$513
Showing 1-10 of 37 resultsSorted by cheapest first
Best time to book a flight from San Diego to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from San Diego with our price prediction graph.
SAN-MIA
SAN-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Florida Keys
SAN-zzEOA
SAN-MIA
SAN-EYW
What is the cheapest month to book a flight from San Diego to Florida Keys?
Currently, August is the cheapest month in which you can book a flight from San Diego to Florida Keys (average of $85). Flying from San Diego to Florida Keys in March is currently the most expensive (average of $257). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from San Diego to Florida Keys?
To ensure you get the cheapest price possible for a flight from San Diego to Florida Keys, you should look to book at least 81 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated June 10, 2026.
Read through reviews of airlines operating flights from San Diego to Florida Keys, such as Alaska Airlines,Southwest, andDelta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Food
7.0
Boarding
8.1
Entertainment
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Comfort
7.8
Crew
8.5
Food
7.0
Boarding
8.1
Entertainment
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Comfort
7.8
Crew
8.5
Food
7.0
Boarding
8.1
Entertainment
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Comfort
7.8
Crew
8.5
Food
7.0
Boarding
8.1
Entertainment
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Comfort
7.8
Crew
8.5
Food
7.0
Boarding
8.1
Entertainment
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Comfort
7.8
Crew
8.5
Food
7.0
Boarding
8.1
Entertainment
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Related info for your journey
Find useful and relevant information for your journey from San Diego to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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San Diego and Florida Keys flights
Browse other San Diego and Florida Keys flight options. Last updated on June 10, 2026.
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San Diego to Florida Keys flights
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Top airline flying from San Diego to Florida Keys
Discover the top airline that operate flights from San Diego to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$314 | Average$459 | FlexibilityNo cancel fee | On-time71% |