Cheap flights from Florida Keys to San Diego (SAN)

San Diego (SAN), located 2.6 mi from the city center, is the airport you fly into when you book flights from Florida Keys to San Diego.

For as low as $482, Southwest can have you in San Diego from Florida Keys in 9h 36m. Florida Keys and San Diego are separated by a distance of 2262 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

The cheapest airlines for a one-way flight from Florida Keys to San Diego are Frontier ($78), United Airlines ($128), and Delta ($128).

Yes. In addition to deals on Florida Keys to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to San Diego.

Yes. Cheapflights offers flight deals from Florida Keys to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Currently, September is the cheapest month in which you can book a flight from Florida Keys to San Diego (average of $100). Flying from Florida Keys to San Diego in August is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.