$70+ Cheap flights from Detroit Metropolitan Wayne County Airport to St. Louis (DTW - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
May 24 — May 311
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Lambert-St Louis are usually found in July or August, booked 40 days in advance, depart on a Thursday or Saturday and return on a Friday
Cheap flight deals from Detroit to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to St. LouisExplore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
Explore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
This Expedia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:44 pm
DTW
- STL
1 stop12h 37m
Frontier
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/21![Frontier logo]()
$140
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:55 am
DTW
- STL
1 stop12h 28m
Frontier
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/19![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:55 am
DTW
- STL
1 stop12h 28m
Frontier
Mon 5/255:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/20![Frontier logo]()
$166
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop10h 49m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop5h 06m
Frontier
Deal found 4/20![Frontier logo]()
$180
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:55 am
DTW
- STL
1 stop12h 28m
Frontier
Sun 5/248:08 pm
STL
- DTW
1 stop26h 51m
Frontier
Deal found 4/19![Frontier logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:05 am
DTW
- STL
1 stop12h 18m
Frontier
Tue 6/26:33 pm
STL
- DTW
1 stop21h 40m
Frontier
Deal found 4/23![Frontier logo]()
$199
This Frontier deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:55 am
DTW
- STL
1 stop12h 28m
Frontier
Sat 6/135:06 pm
STL
- DTW
1 stop6h 38m
Frontier
Deal found 4/22![Frontier logo]()
$200
This Expedia deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:44 pm
DTW
- STL
1 stop12h 13m
Frontier
Sat 6/68:08 pm
STL
- DTW
1 stop26h 51m
Frontier
Deal found 4/20![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Mon 5/185:27 pm
STL
- DTW
1 stop18h 09m
Frontier
Deal found 4/20![Frontier logo]()
$202
This Expedia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:50 am
DTW
- STL
1 stop11h 04m
Frontier
Sat 5/165:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/21![Frontier logo]()
$205
Best flights from Detroit to St. LouisDiscover carefully curated flight deals from Detroit to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
Discover carefully curated flight deals from Detroit to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Tue 6/25:35 am
STL
- DTW
1 stop3h 10m
Southwest
Deal found 4/23![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:01 am
DTW
- STL
1 stop4h 31m
Delta
Fri 5/291:59 pm
STL
- DTW
Nonstop1h 34m
Delta
Deal found 4/23![Delta logo]()
$287
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:00 am
DTW
- STL
2 stops9h 46m
United Airlines
Sat 6/65:41 pm
STL
- DTW
1 stop5h 02m
United Airlines
Deal found 4/23![United Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Fri 6/57:55 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/20![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:45 am
DTW
- STL
Nonstop1h 44m
Delta
Sat 6/136:21 am
STL
- DTW
1 stop4h 22m
Delta
Deal found 4/22![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Fri 5/2911:50 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/21![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:01 am
DTW
- STL
1 stop4h 27m
Delta
Sun 7/266:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 4/22![Delta logo]()
$360
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Sun 5/3110:15 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/19![Southwest logo]()
$345
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:30 pm
DTW
- STL
Nonstop1h 39m
Delta
Sun 5/316:45 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 4/19![Delta logo]()
$361
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:30 am
DTW
- STL
2 stops13h 25m
Southwest
Sat 6/133:45 pm
STL
- DTW
2 stops7h 00m
Southwest
Deal found 4/22![Southwest logo]()
$356
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:55 am
DTW
- STL
Nonstop1h 35m
Southwest
Fri 6/197:55 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/23![Southwest logo]()
$361
Last-minute flights from Detroit to St. LouisDiscover last-minute flight deals from Detroit to St. Louis. Data last updated April 24, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to St. Louis. Data last updated April 24, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop10h 49m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop5h 06m
Frontier
Deal found 4/20![Frontier logo]()
$180
This Expedia deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop10h 49m
Frontier
Fri 5/85:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/23![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Mon 5/185:27 pm
STL
- DTW
1 stop18h 09m
Frontier
Deal found 4/20![Frontier logo]()
$202
This Expedia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:50 am
DTW
- STL
1 stop11h 04m
Frontier
Sat 5/165:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/21![Frontier logo]()
$205
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:55 am
DTW
- STL
1 stop12h 28m
Frontier
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/19![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:55 am
DTW
- STL
1 stop12h 28m
Frontier
Sun 5/248:08 pm
STL
- DTW
1 stop26h 51m
Frontier
Deal found 4/19![Frontier logo]()
$185
This Expedia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:44 pm
DTW
- STL
1 stop12h 37m
Frontier
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/21![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:55 am
DTW
- STL
1 stop12h 28m
Frontier
Mon 5/255:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/20![Frontier logo]()
$166
This Expedia deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:55 am
DTW
- STL
1 stop12h 28m
Frontier
Mon 5/255:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/20![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:05 am
DTW
- STL
1 stop12h 18m
Frontier
Tue 6/26:33 pm
STL
- DTW
1 stop21h 40m
Frontier
Deal found 4/23![Frontier logo]()
$199
One-way flights from Detroit to St. LouisSearch for one-way flight options from Detroit to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
Search for one-way flight options from Detroit to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
This Priceline deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:31 pm
DTW
- STL
1 stop5h 02m
Frontier
Deal found 4/20![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:55 am
DTW
- STL
1 stop12h 28m
Frontier
Deal found 4/20![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Deal found 4/19![Frontier logo]()
$82
This Priceline deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:20 pm
DTW
- STL
1 stop7h 03m
Frontier
Deal found 4/20![Frontier logo]()
$90
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:55 am
DTW
- STL
1 stop12h 28m
Frontier
Deal found 4/20![Frontier logo]()
$96
This Frontier deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:55 am
DTW
- STL
1 stop12h 28m
Frontier
Deal found 4/22![Frontier logo]()
$97
This Frontier deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:55 am
DTW
- STL
1 stop12h 28m
Frontier
Deal found 4/19![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:38 pm
DTW
- STL
1 stop24h 52m
Frontier
Deal found 4/23![Frontier logo]()
$104
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Deal found 4/23![Southwest logo]()
$107
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 4/22![Southwest logo]()
$108
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/151:20 pm
DTW
- STL
1 stop7h 03m
Frontier
Deal found 4/20![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:20 am
DTW
- STL
2 stops36h 46m
Frontier
Deal found 4/19![Frontier logo]()
$114
Find flight deals from Detroit to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $140 (Expedia) |
One-way from | $70 (Priceline) |
Popular in | April |
Cheapest in | July |
Average price | $441 |
Good round-trip deal | $350 or less |
Good one-way deal | $189 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Mon 6/1
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Tue 6/2
5:35 am-9:45 am
1 stop3h 10m
$257
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 5/22
7:01 am-10:32 am
1 stop4h 31m
Lambert-St Louis
Fri 5/29
1:59 pm-4:33 pm
Nonstop1h 34m
$287
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Mon 6/1
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Fri 6/5
7:55 pm-10:25 pm
Nonstop1h 30m
$304
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 5/28
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Fri 5/29
11:50 am-2:20 pm
Nonstop1h 30m
$304
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 6/2
7:00 am-3:46 pm
2 stops9h 46m
Lambert-St Louis
Sat 6/6
5:41 pm-11:43 pm
1 stop5h 02m
$321
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 6/6
8:45 am-9:29 am
Nonstop1h 44m
Lambert-St Louis
Sat 6/13
6:21 am-11:43 am
1 stop4h 22m
$329
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 5/29
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Sun 5/31
10:15 am-12:45 pm
Nonstop1h 30m
$345
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 6/6
5:30 am-5:55 pm
2 stops13h 25m
Lambert-St Louis
Sat 6/13
3:45 pm-11:45 pm
2 stops7h 00m
$356
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 7/22
7:01 am-10:28 am
1 stop4h 27m
Lambert-St Louis
Sun 7/26
6:30 am-9:04 am
Nonstop1h 34m
$360
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 5/29
8:30 pm-9:09 pm
Nonstop1h 39m
Lambert-St Louis
Sun 5/31
6:45 am-9:19 am
Nonstop1h 34m
$361
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Detroit to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to St. Louis in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Detroit with our price prediction graph.
DTW-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to St. Louis
Prices
Airlines
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to St. Louis?
The price you pay for your flight from Detroit Metropolitan Wayne County Airport to St. Louis may vary depending on when you book. For the best chance of a lower fare, look to book 39 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to St. Louis?
Currently, July is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to St. Louis (average of $134). Flying from Detroit Metropolitan Wayne County Airport to St. Louis in April is currently the most expensive (average of $441). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to STL?
Find hourly flight availability from Detroit to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2026.
Unlike in the morning, when flights are generally more expensive, you can save up to 24% on flights from Detroit Metropolitan Wayne County Airport to St. Louis by exploring options for tickets at noon.
What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to St. Louis?
Use this chart to determine the cheapest time to fly round-trip from Detroit to St. Louis. Price data was last updated on April 18, 2026.
Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to St. Louis flight should consider departing on Friday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
The best insider tips for Detroit Metropolitan Wayne County Airport to St. Louis flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Detroit Metropolitan Wayne County Airport to St. Louis trip
Our travel experts
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated April 24, 2026.
Read reviews from past customers who have flown Southwest,Delta, andSpirit Airlines from Detroit Metropolitan Wayne County Airport to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Detroit to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Detroit and St. Louis flights
Browse other Detroit and St. Louis flight options. Last updated on April 24, 2026.
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Top 4 airlines flying from Detroit to St. Louis
Discover the top 4 airlines that operate flights from Detroit to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$98 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$120 | Average$346 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$137 | Average$320 | FlexibilityNo cancel fee | On-time63% |