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St. Louis

$249+ Cheap flights from Mobile to St. Louis (MOB - STL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
MOB — STL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Mobile to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Mobile (MOB) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$249
(Delta)

Popular in

February

Cheapest in

November

Average price

$328
From Mobile to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($25 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mobile to St. Louis

Cheapest flights from Mobile to St. Louis
Explore the most affordable flight options available from Mobile to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:23 pmMOB - STL
1 stop4h 37mUnited Airlines
Tue 9/306:15 amSTL - MOB
1 stop5h 28mUnited Airlines
Deal found 9/11$259
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/264:58 pmMOB - STL
1 stop6h 09mAmerican Airlines
Tue 9/306:10 amSTL - MOB
2 stops10h 23mAmerican Airlines
Deal found 9/11$264
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:59 pmMOB - STL
1 stop4h 50mAmerican Airlines
Sat 10/115:20 amSTL - MOB
1 stop7h 05mAmerican Airlines
Deal found 9/11$274
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/179:10 amMOB - STL
1 stop5h 25mDelta
Sat 10/45:11 pmSTL - MOB
1 stop6h 01mDelta
Deal found 9/10$279
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/171:52 pmMOB - STL
1 stop4h 40mAmerican Airlines
Sat 10/43:59 pmSTL - MOB
1 stop7h 03mAmerican Airlines
Deal found 9/11$294
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/175:09 pmMOB - STL
1 stop5h 07mUnited Airlines
Sat 10/412:25 pmSTL - MOB
2 stops9h 23mUnited Airlines
Deal found 9/11$299
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:40 amMOB - STL
2 stops6h 51mAmerican Airlines
Sun 9/285:27 amSTL - MOB
1 stop6h 54mAmerican Airlines
Deal found 9/9$304
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:23 pmMOB - STL
1 stop4h 37mUnited Airlines
Sun 10/126:15 amSTL - MOB
1 stop5h 28mUnited Airlines
Deal found 9/9$461
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:40 amMOB - STL
2 stops9h 23mAmerican Airlines
Sun 11/22:17 pmSTL - MOB
2 stops9h 39mAmerican Airlines
Deal found 9/9$462

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mobile to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Mobile to St. Louis that are best for you.

Fly from

Mobile

Fly to

St. Louis

Route

Depart

Return

Price

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Wed 2/18

7:15 pm-11:40 pm

1 stop4h 25m

Lambert-St Louis

Sat 2/21

10:00 am-3:52 pm

1 stop5h 52m

$249

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Fri 9/26

5:23 pm-10:00 pm

1 stop4h 37m

Lambert-St Louis

Tue 9/30

6:15 am-11:43 am

1 stop5h 28m

$259

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Thu 10/9

6:59 pm-11:49 pm

1 stop4h 50m

Lambert-St Louis

Sat 10/11

5:20 am-12:25 pm

1 stop7h 05m

$274

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Wed 9/24

5:55 pm-10:50 pm

1 stop4h 55m

Lambert-St Louis

Sun 9/28

5:27 am-12:21 pm

1 stop6h 54m

$299

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Wed 2/18

5:22 am-2:55 pm

2 stops9h 33m

Lambert-St Louis

Sat 2/21

2:32 pm-9:32 pm

1 stop7h 00m

$324

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Fri 9/26

5:23 pm-10:00 pm

1 stop4h 37m

$304

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Wed 9/17

1:52 pm-6:32 pm

1 stop4h 40m

$345

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Thu 9/18

12:29 pm-7:33 pm

1 stop7h 04m

$475

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Thu 9/18

7:00 am-7:27 pm

2 stops12h 27m

$560

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Mobile to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mobile with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mobile to St. Louis

What is the cheapest month to book a flight from Mobile to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Mobile to St. Louis (average of $311). Flying from Mobile to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MOB to STL?

Find hourly flight availability from Mobile to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Mobile to St. Louis in the afternoon. Doing so could potentially save you 31% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Mobile to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Mobile to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mobile to St. Louis?

    Departing from Mobile to St. Louis will take you 4h 25m. There are 570 mi between Mobile and St. Louis. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Mobile to St. Louis round-trip?

    Our cheapest airline available from Mobile to St. Louis is Delta. Our recent data shows that you can find tickets from as low as $248 on this airline. An additional option worth looking into is American Airlines, starting at $253. These flights start at 25% lower than the current average price 3 months from now.

  • Can I find deals for flights from Mobile to St. Louis that include hotel bookings?

    Yes. In addition to deals on Mobile to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mobile to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mobile to St. Louis.

  • Can I find deals for business class flights from Mobile to St. Louis?

    Yes. Cheapflights offers flight deals from Mobile to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mobile to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Mobile to St. Louis (average of $311). Flying from Mobile to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Mobile to St. Louis

Discover the top 2 airlines that operate flights from Mobile to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$314FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$253Average$318FlexibilityNo cancel feeOn-time71%

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