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$338+ Cheap flights from St. Louis (STL) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from St. Louis to Spain

Cheapest flights from St. Louis to Spain
Explore the most affordable flight options available from St. Louis to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:05 pmSTL - MAD
2 stops20h 35mUnited Airlines
Wed 12/315:55 amMAD - STL
2 stops20h 23mUnited Airlines
Deal found 12/22$753
This oojo deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:35 pmSTL - MAD
2 stops36h 00mBritish Airways
Mon 1/128:50 pmMAD - STL
2 stops31h 25mBritish Airways
Deal found 12/22$771
This Expedia deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:04 amSTL - MAD
1 stop19h 21mIberia
Sun 1/115:40 pmMAD - STL
2 stops36h 04mIberia
Deal found 12/22$792
This Finnair deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:09 amSTL - MAD
1 stop13h 36mMultiple Airlines
Wed 12/311:00 pmMAD - STL
1 stop13h 30mMultiple Airlines
Deal found 12/22$799
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 amSTL - BCN
2 stops20h 05mUnited Airlines
Sun 12/2810:30 amBCN - STL
1 stop15h 52mUnited Airlines
Deal found 12/22$814
This oojo deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:01 pmSTL - MAD
2 stops39h 24mBritish Airways
Sun 1/116:05 pmMAD - STL
2 stops35h 39mBritish Airways
Deal found 12/22$814
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:35 pmSTL - BCN
2 stops30h 45mUnited Airlines
Mon 12/2910:30 amBCN - STL
1 stop15h 52mUnited Airlines
Deal found 12/21$895
This Booking.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 amSTL - BCN
2 stops20h 05mMultiple Airlines
Sun 12/2811:00 amBCN - STL
1 stop19h 33mMultiple Airlines
Deal found 12/22$905
This oojo deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:06 pmSTL - BCN
2 stops22h 44mBritish Airways
Sun 12/289:20 pmBCN - STL
2 stops33h 24mBritish Airways
Deal found 12/22$908
This Ovago deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:00 amSTL - MAD
1 stop17h 45mFinnair
Mon 1/124:25 pmMAD - STL
1 stop23h 43mFinnair
Deal found 12/22$932
This oojo deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:04 pmSTL - MAD
1 stop32h 41mBritish Airways
Wed 12/311:00 pmMAD - STL
1 stop13h 30mBritish Airways
Deal found 12/21$958
This Expedia deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:05 pmSTL - MAD
2 stops56h 55mMultiple Airlines
Mon 12/291:45 pmMAD - STL
2 stops33h 42mMultiple Airlines
Deal found 12/21$1,015

Find flight deals from St. Louis to Spain

Keep the following information in mind while searching for St. Louis to Spain flight deals. Data was last updated December 23, 2025.

Round-trip from

$436
(Kiwi.com)

One-way from

$338
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$835
From Lambert-St Louis to Spain
Search Deals
One-way flight from Lambert-St Louis to Spain
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($283 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from St. Louis to Spain that are best for you.

Fly from

St. Louis

Fly to

Spain

Route

Depart

Return

Price

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Wed 1/21

11:22 am-5:50 pm

2 stops23h 28m

Madrid Barajas

Sun 1/25

5:55 am-1:55 pm

1 stop15h 00m

$467

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Mon 1/19

6:57 pm-8:40 am

1 stop30h 43m

Barcelona-El Prat

Sun 2/1

10:55 am-5:50 pm

1 stop13h 55m

$475

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Thu 3/5

6:00 am-11:55 am

2 stops22h 55m

Madrid Barajas

Wed 3/18

1:45 pm-11:52 pm

1 stop16h 07m

$476

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Wed 2/11

7:15 am-8:50 am

1 stop18h 35m

Barcelona-El Prat

Mon 2/16

11:00 am-10:05 pm

1 stop18h 05m

$484

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Wed 1/21

6:25 am-8:00 am

1 stop18h 35m

Barcelona-El Prat

Thu 1/29

10:15 am-8:06 pm

1 stop16h 51m

$484

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Wed 1/21

9:57 am-9:15 am

2 stops16h 18m

Madrid Barajas

Sun 1/25

5:55 am-1:55 pm

1 stop15h 00m

$484

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Sun 2/1

11:55 am-8:50 am

1 stop13h 55m

Barcelona-El Prat

Tue 2/17

11:00 am-10:05 pm

1 stop18h 05m

$484

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Tue 1/20

9:45 am-5:05 pm

2 stops24h 20m

Barcelona-El Prat

Thu 1/29

10:15 am-8:06 pm

1 stop16h 51m

$488

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Wed 3/11

8:30 am-11:45 am

2 stops21h 15m

Madrid Barajas

Wed 3/18

5:55 am-2:55 pm

1 stop15h 00m

$488

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Thu 1/22

6:25 am-8:50 am

2 stops19h 25m

Barcelona-El Prat

Mon 1/26

10:15 am-8:06 pm

1 stop16h 51m

$488

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 54 results
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Best time to book a flight from St. Louis to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Spain

What is the cheapest month to book a flight from St. Louis to Spain?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Spain (average of $513). Flying from St. Louis to Spain in June is currently the most expensive (average of $906). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to ES?

Find hourly flight availability from St. Louis to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 9% on flights from St. Louis to Spain by exploring options for tickets at noon.

What is the cheapest day to fly from St. Louis to Spain?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Spain. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their St. Louis to Spain flight should consider departing on Wednesday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated December 23, 2025.
Get a feel of what it's like to fly with United Airlines, American Airlines, and Air Canada from St. Louis to Spain by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,105 reviews

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,105 reviews
United Airlines
7.4
Good
9,105 reviews

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
American Airlines
7.2
Good
11,054 reviews
United Airlines
7.4
Good
9,105 reviews

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
Air Canada
7.1
Good
10,551 reviews
United Airlines
7.4
Good
9,105 reviews

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
Iberia
7.0
Good
3,056 reviews
United Airlines
7.4
Good
9,105 reviews

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
British Airways
6.7
Okay
7,605 reviews
United Airlines
7.4
Good
9,105 reviews

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Spain?

    Most people fly from Lambert-St Louis (STL) if they book a flight from St. Louis to Spain. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • How long is the flight from St. Louis to Spain?

    For as low as $476, Lufthansa can have you in Spain from St. Louis in 22h 55m. St. Louis and Spain are separated by a distance of 4414 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from St. Louis to Spain one-way?

    One-way options have recently been found by users for as low as $322 on American Airlines. Other airlines that offer cheap prices include United Airlines from $438 and Lufthansa from $450 one-way.

  • What are the most popular routes from St. Louis to Spain?

    Most travelers choose Lambert-St Louis - Barcelona-El Prat, Lambert-St Louis - Madrid Barajas or Lambert-St Louis - Santa Cruz de Tenerife Tenerife-Norte when deciding on the best route from St. Louis to Spain.

  • Can I find deals for flights from St. Louis to Spain that include hotel bookings?

    Yes. In addition to deals on St. Louis to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Spain.

  • Can I find deals for business class flights from St. Louis to Spain?

    Yes. Cheapflights offers flight deals from St. Louis to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Spain?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Spain (average of $513). Flying from St. Louis to Spain in June is currently the most expensive (average of $906). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from St. Louis to Spain

Discover the top 8 airlines that operate flights from St. Louis to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$516Average$831FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$524Average$1,066FlexibilityNo cancel feeOn-time76%
DeltaCheapest$552Average$899FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$567Average$970FlexibilityNo cancel feeOn-time69%
IberiaCheapest$586Average$939FlexibilityNo cancel feeOn-time77%
American AirlinesCheapest$587Average$988FlexibilityNo cancel feeOn-time71%
KLMCheapest$590Average$782FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$624Average$1,086FlexibilityNo cancel feeOn-time67%

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