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$375+ Cheap flights from Myrtle Beach (MYR) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — MAD
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Spain

Keep the following information in mind while searching for Myrtle Beach to Spain flight deals. Data was last updated October 16, 2025.

Round-trip from

$434
(KLM)

One-way from

$375
(FlightHub)

Popular in

March

Cheapest in

November

Average price

$1,100
From Myrtle Beach Intl to Spain
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One-way flight from Myrtle Beach Intl to Spain
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Highest demand for flights based on searches. 12% potential increase in price ($166 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($104 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Myrtle Beach to Spain

Best flights from Myrtle Beach to Spain
Discover carefully curated flight deals from Myrtle Beach to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 16, 2025.

This KLM deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1711:30 amMYR - BCN
1 stop15h 10mKLM
Tue 2/2410:55 amBCN - MYR
1 stop18h 40mKLM
Deal found 10/15$434
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1711:30 amMYR - BCN
2 stops23h 35mDelta
Tue 2/2410:15 amBCN - MYR
2 stops19h 20mDelta
Deal found 10/15$457
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:14 amMYR - BCN
1 stop15h 46mAmerican Airlines
Fri 3/611:35 amBCN - MYR
2 stops18h 01mAmerican Airlines
Deal found 10/16$625
This Booking.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2811:14 amMYR - BCN
2 stops24h 41mBritish Airways
Fri 3/63:35 pmBCN - MYR
2 stops47h 38mBritish Airways
Deal found 10/16$707
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/111:25 amMYR - BCN
2 stops14h 55mUnited Airlines
Wed 4/86:50 amBCN - MYR
2 stops37h 48mUnited Airlines
Deal found 10/15$756
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:37 pmMYR - MAD
1 stop14h 48mMultiple Airlines
Wed 4/811:35 amMAD - MYR
2 stops17h 45mMultiple Airlines
Deal found 10/15$797
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/171:25 pmMYR - BCN
3 stops38h 10mAir Canada
Tue 2/241:50 pmBCN - MYR
3 stops31h 29mAir Canada
Deal found 10/16$804
This KLM deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:45 pmMYR - BCN
2 stops15h 40mKLM
Wed 4/811:35 amBCN - MYR
1 stop18h 00mKLM
Deal found 10/15$752
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:45 pmMYR - MAD
2 stops18h 45mDelta
Wed 4/86:00 amMAD - MYR
2 stops23h 35mDelta
Deal found 10/15$760
This Expedia deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:14 amMYR - BCN
1 stop15h 46mBritish Airways
Fri 3/612:30 pmBCN - MYR
1 stop27h 53mBritish Airways
Deal found 10/16$768
This KLM deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1010:55 amMYR - MAD
2 stops21h 45mKLM
Wed 3/118:30 pmMAD - MYR
2 stops32h 05mKLM
Deal found 10/15$1,221
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/102:29 pmMYR - MAD
1 stop10h 16mAmerican Airlines
Wed 3/111:00 pmMAD - MYR
1 stop15h 26mAmerican Airlines
Deal found 10/14$1,357
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/282:29 pmMYR - EAS
2 stops36h 11mAmerican Airlines
Tue 3/319:20 amEAS - MYR
2 stops36h 24mAmerican Airlines
Deal found 10/14$1,623

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Spain that are best for you.

Fly from

Myrtle Beach

Fly to

Spain

Route

Depart

Return

Price

Myrtle BeachBarcelona

MYR - BCN

MYRBCN

Myrtle Beach Intl

Tue 2/17

11:30 am-8:40 am

1 stop15h 10m

Barcelona-El Prat

Tue 2/24

10:55 am-11:35 pm

1 stop18h 40m

$434

Myrtle BeachBarcelona

MYR - BCN

MYRBCN

Myrtle Beach Intl

Tue 2/17

11:30 am-5:05 pm

2 stops23h 35m

Barcelona-El Prat

Tue 2/24

10:15 am-11:35 pm

2 stops19h 20m

$457

Myrtle BeachBarcelona

MYR - BCN

MYRBCN

Myrtle Beach Intl

Fri 2/27

11:14 am-9:00 am

1 stop15h 46m

Barcelona-El Prat

Fri 3/6

11:35 am-11:36 pm

2 stops18h 01m

$625

Myrtle BeachBarcelona

MYR - BCN

MYRBCN

Myrtle Beach Intl

Sat 2/28

11:14 am-5:55 pm

2 stops24h 41m

Barcelona-El Prat

Fri 3/6

3:35 pm-9:13 am

2 stops47h 38m

$707

Myrtle BeachBarcelona

MYR - BCN

MYRBCN

Myrtle Beach Intl

Wed 4/1

6:45 pm-4:25 pm

2 stops15h 40m

Barcelona-El Prat

Wed 4/8

11:35 am-11:35 pm

1 stop18h 00m

$752

Myrtle BeachBarcelona

MYR - BCN

MYRBCN

Myrtle Beach Intl

Wed 4/1

11:25 am-8:20 am

2 stops14h 55m

Barcelona-El Prat

Wed 4/8

6:50 am-2:38 pm

2 stops37h 48m

$756

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Wed 4/1

6:45 pm-7:30 pm

2 stops18h 45m

Madrid Barajas

Wed 4/8

6:00 am-11:35 pm

2 stops23h 35m

$760

Myrtle BeachBarcelona

MYR - BCN

MYRBCN

Myrtle Beach Intl

Fri 2/27

11:14 am-9:00 am

1 stop15h 46m

Barcelona-El Prat

Fri 3/6

12:30 pm-10:23 am

1 stop27h 53m

$768

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Wed 4/1

5:37 pm-2:25 pm

1 stop14h 48m

Madrid Barajas

Wed 4/8

11:35 am-11:20 pm

2 stops17h 45m

$797

Myrtle BeachBarcelona

MYR - BCN

MYRBCN

Myrtle Beach Intl

Tue 2/17

1:25 pm-9:35 am

3 stops38h 10m

Barcelona-El Prat

Tue 2/24

1:50 pm-3:19 pm

3 stops31h 29m

$804

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 18 results
1
2

Best time to book a flight from Myrtle Beach to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Spain

What is the cheapest month to book a flight from Myrtle Beach to Spain?

Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Spain (average of $380). Flying from Myrtle Beach to Spain in June is currently the most expensive (average of $882). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to ES?

Find hourly flight availability from Myrtle Beach to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

When flying from Myrtle Beach to Spain, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 27% versus a flight in the afternoon.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated October 16, 2025.
See what other customers who have flown with KLM and American Airlines from Myrtle Beach to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,404 reviews

Crew

8.4

Entertainment

7.1

Overall

7.7

Comfort

7.6

Food

7.3

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7.7
Good
1,404 reviews
KLM
7.7
Good
1,404 reviews

Crew

8.4

Entertainment

7.1

Overall

7.7

Comfort

7.6

Food

7.3

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
American Airlines
7.2
Good
11,040 reviews
KLM
7.7
Good
1,404 reviews

Crew

8.4

Entertainment

7.1

Overall

7.7

Comfort

7.6

Food

7.3

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Spain?

    For a flight from Myrtle Beach to Spain, you will be flying from Myrtle Beach Intl. Myrtle Beach Intl (MYR) is just 2.1 mi from the center of the city.

  • How long is the flight from Myrtle Beach to Spain?

    Airlines like KLM, Delta, and American Airlines fly from Myrtle Beach to Spain in about 15h 10m. The time it takes to get you to your destination can typically vary by up to 21h 01m. Airlines will cover a distance of 4307 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Myrtle Beach to Spain one-way?

    The cheapest airlines for a one-way flight from Myrtle Beach to Spain are Scandinavian Airlines ($375), American Airlines ($419), and United Airlines ($733).

  • What are the most popular routes from Myrtle Beach to Spain?

    While some choose either Myrtle Beach Intl - Madrid Barajas or Myrtle Beach Intl - San Sebastián, Myrtle Beach Intl - Barcelona-El Prat is the most popular route from Myrtle Beach to Spain.

  • Can I find deals for flights from Myrtle Beach to Spain that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Spain.

  • Can I find deals for business class flights from Myrtle Beach to Spain?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Spain?

    Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Spain (average of $380). Flying from Myrtle Beach to Spain in June is currently the most expensive (average of $882). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Myrtle Beach to Spain

Discover the top 2 airlines that operate flights from Myrtle Beach to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$637Average$917FlexibilityNo cancel feeOn-time71%
KLMCheapest$707Average$1,163FlexibilityNo cancel feeOn-time75%

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