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South Dakota

$285+ Cheap flights from Medford (MFR) to South Dakota

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — FSD
Dec 16 — Dec 231
Tue 12/16
Tue 12/23
1 adult, Economy
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Cheap flight deals from Medford to South Dakota

Keep the following information in mind while searching for Medford to South Dakota flight deals. Data was last updated November 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$285
(American Airlines)

Popular in

July

Cheapest in

January

Average price

$552
Provider with most accurate pricing for Medford-Sioux Falls Joe Foss Field flight deals.
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Provider most trusted by Cheapflights users for Medford-Sioux Falls Joe Foss Field flights.
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From Medford to South Dakota
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Highest demand for flights based on searches. 20% potential increase in price ($127 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Medford to South Dakota

Cheapest flights from Medford to South Dakota
Explore the most affordable flight options available from Medford to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 16, 2025.

This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:00 pmMFR - FSD
1 stop6h 32mAmerican Airlines
Wed 12/178:05 amFSD - MFR
1 stop7h 24mAmerican Airlines
Deal found 11/16$285
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:41 pmMFR - FSD
2 stops8h 31mDelta
Wed 12/171:30 pmFSD - MFR
2 stops11h 32mDelta
Deal found 11/16$335
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:00 amMFR - FSD
1 stop5h 51mUnited Airlines
Wed 12/1711:20 amFSD - MFR
2 stops12h 09mUnited Airlines
Deal found 11/16$430
This American Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/295:20 amMFR - FSD
1 stop6h 41mAmerican Airlines
Wed 12/32:35 pmFSD - MFR
1 stop7h 56mAmerican Airlines
Deal found 11/14$550
This United Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/295:00 amMFR - FSD
1 stop13h 23mUnited Airlines
Wed 12/38:00 amFSD - MFR
2 stops15h 29mUnited Airlines
Deal found 11/14$669
This United Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:00 amMFR - FSD
1 stop13h 00mUnited Airlines
Fri 12/266:00 amFSD - MFR
1 stop17h 12mUnited Airlines
Deal found 11/14$756
This Delta deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:41 pmMFR - FSD
2 stops8h 31mDelta
Fri 12/265:00 amFSD - MFR
2 stops9h 54mDelta
Deal found 11/14$1,089

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 16, 2025.
Use the filters below to find and compare flights from Medford to South Dakota that are best for you.

Fly from

Medford

Fly to

South Dakota

Route

Depart

Return

Price

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Tue 12/9

3:00 pm-11:32 pm

1 stop6h 32m

Sioux Falls Joe Foss Field

Wed 12/17

8:05 am-1:29 pm

1 stop7h 24m

$285

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Tue 12/9

12:41 pm-11:12 pm

2 stops8h 31m

Sioux Falls Joe Foss Field

Wed 12/17

1:30 pm-11:02 pm

2 stops11h 32m

$335

MedfordRapid City

MFR - RAP

MFRRAP

Medford

Fri 3/6

5:10 am-1:13 pm

1 stop7h 03m

Rapid City

Tue 3/10

2:45 pm-9:33 pm

1 stop7h 48m

$339

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Fri 2/20

5:25 am-2:28 pm

1 stop7h 03m

Sioux Falls Joe Foss Field

Tue 2/24

8:01 am-1:34 pm

1 stop7h 33m

$374

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Fri 2/20

6:25 pm-10:46 am

2 stops14h 21m

Sioux Falls Joe Foss Field

Tue 2/24

5:00 pm-9:18 pm

1 stop6h 18m

$380

MedfordRapid City

MFR - RAP

MFRRAP

Medford

Wed 4/8

5:00 am-1:08 pm

1 stop7h 08m

Rapid City

Sun 4/12

2:45 pm-9:26 pm

1 stop7h 41m

$394

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Fri 2/20

5:20 pm-3:37 pm

2 stops20h 17m

Sioux Falls Joe Foss Field

Tue 2/24

10:50 am-10:57 am

2 stops26h 07m

$423

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Tue 12/9

5:00 am-12:51 pm

1 stop5h 51m

Sioux Falls Joe Foss Field

Wed 12/17

11:20 am-9:29 pm

2 stops12h 09m

$430

MedfordRapid City

MFR - RAP

MFRRAP

Medford

Fri 3/6

5:20 pm-10:28 pm

2 stops28h 08m

Rapid City

Tue 3/10

10:40 am-11:09 pm

2 stops13h 29m

$509

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Sat 11/29

5:20 am-2:01 pm

1 stop6h 41m

Sioux Falls Joe Foss Field

Wed 12/3

2:35 pm-8:31 pm

1 stop7h 56m

$550

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/15

Showing 1-10 of 15 results
1
2

Best time to book a flight from Medford to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to South Dakota
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated November 16, 2025.
Peruse reviews from past customers who have flown with United Airlines from Medford to South Dakota to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,017 reviews

Crew

8.1

Food

6.6

Entertainment

7.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,017 reviews
United Airlines
7.4
Good
9,017 reviews

Crew

8.1

Food

6.6

Entertainment

7.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Medford to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to South Dakota?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to South Dakota from Medford.

  • How long is the flight from Medford to South Dakota?

    American Airlines, Delta, and United Airlines can get you from Medford to South Dakota in just under 6h 32m. Your travel time can differ by up to 1h 59m. Airlines will cover a distance of 1317 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Medford to South Dakota one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $295. Users have also found prices from $295 and $300 on American Airlines and Delta, respectively.

  • Can I find deals for flights from Medford to South Dakota that include hotel bookings?

    Yes. In addition to deals on Medford to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to South Dakota.

  • Can I find deals for business class flights from Medford to South Dakota?

    Yes. Cheapflights offers flight deals from Medford to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Medford to South Dakota

Discover the top airline that operate flights from Medford to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$258Average$438FlexibilityNo cancel feeOn-time69%

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