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South Dakota

$186+ Cheap flights from Knoxville (TYS) to South Dakota

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FSD
Oct 14 — Oct 211
Tue 10/14
Tue 10/21
1 adult, Economy
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Cheap flight deals from Knoxville to South Dakota

Keep the following information in mind while searching for Knoxville to South Dakota flight deals. Data was last updated September 14, 2025.

Round-trip from

$259
(Delta)

One-way from

$186
(Delta)

Popular in

June

Cheapest in

January

Average price

$448
From Knoxville McGhee Tyson to South Dakota
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One-way flight from Knoxville McGhee Tyson to South Dakota
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Highest demand for flights based on searches. 11% potential increase in price ($57 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Knoxville to South Dakota

Cheapest flights from Knoxville to South Dakota
Explore the most affordable flight options available from Knoxville to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2025.

This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/274:40 pmTYS - RAP
1 stop5h 54mUnited Airlines
Wed 10/112:56 pmRAP - TYS
1 stop7h 32mUnited Airlines
Deal found 9/11$289
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:40 amTYS - RAP
1 stop5h 13mDelta
Mon 10/272:26 pmRAP - TYS
1 stop6h 29mDelta
Deal found 9/12$309
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:40 amTYS - RAP
1 stop5h 13mDelta
Wed 10/2910:33 amRAP - TYS
2 stops10h 34mDelta
Deal found 9/12$314
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:57 pmTYS - FSD
1 stop5h 02mAmerican Airlines
Tue 12/306:45 amFSD - TYS
2 stops10h 15mAmerican Airlines
Deal found 9/13$324
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:04 pmTYS - RAP
1 stop6h 32mDelta
Mon 10/274:34 pmRAP - TYS
1 stop4h 21mDelta
Deal found 9/12$324
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:24 pmTYS - FSD
2 stops11h 33mAmerican Airlines
Tue 12/306:45 amFSD - TYS
2 stops10h 15mAmerican Airlines
Deal found 9/13$329
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:04 pmTYS - RAP
1 stop6h 32mDelta
Wed 10/2910:33 amRAP - TYS
2 stops10h 34mDelta
Deal found 9/12$329
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:23 amTYS - FSD
1 stop8h 05mAmerican Airlines
Tue 12/306:45 amFSD - TYS
2 stops10h 15mAmerican Airlines
Deal found 9/13$335
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:30 amTYS - FSD
1 stop8h 09mAmerican Airlines
Sat 9/205:33 pmFSD - TYS
1 stop5h 48mAmerican Airlines
Deal found 9/14$339
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/154:40 pmTYS - RAP
1 stop5h 54mUnited Airlines
Sat 10/181:44 pmRAP - TYS
1 stop7h 06mUnited Airlines
Deal found 9/13$339
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2412:35 pmTYS - RAP
1 stop5h 28mAmerican Airlines
Mon 10/274:28 pmRAP - TYS
1 stop5h 23mAmerican Airlines
Deal found 9/12$343
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:00 amTYS - RAP
1 stop5h 13mUnited Airlines
Sat 10/259:00 amRAP - TYS
2 stops11h 50mUnited Airlines
Deal found 9/12$344

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from Knoxville to South Dakota that are best for you.

Fly from

Knoxville

Fly to

South Dakota

Route

Depart

Return

Price

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Sat 2/21

6:45 am-10:05 am

1 stop5h 20m

Rapid City

Wed 2/25

4:00 pm-11:00 pm

1 stop5h 00m

$259

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Sat 9/27

4:40 pm-8:34 pm

1 stop5h 54m

Rapid City

Wed 10/1

12:56 pm-10:28 pm

1 stop7h 32m

$289

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Sat 10/25

6:00 am-11:36 am

1 stop7h 36m

Rapid City

Mon 10/27

4:28 pm-11:51 pm

1 stop5h 23m

$314

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Sat 10/25

6:40 am-9:53 am

1 stop5h 13m

Rapid City

Wed 10/29

10:33 am-11:07 pm

2 stops10h 34m

$314

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Wed 12/24

8:30 am-6:59 pm

2 stops11h 29m

Sioux Falls Joe Foss Field

Tue 12/30

6:45 am-7:41 pm

2 stops11h 56m

$340

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Sun 9/28

7:00 am-2:09 pm

1 stop8h 09m

Sioux Falls Joe Foss Field

Thu 10/2

9:17 am-9:54 am

1 stop23h 37m

$347

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Sun 12/21

9:56 pm-6:02 pm

1 stop21h 06m

Sioux Falls Joe Foss Field

Wed 12/31

9:57 am-10:51 pm

1 stop11h 54m

$389

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 10/17

6:04 pm-10:57 pm

1 stop5h 53m

Sioux Falls Joe Foss Field

Wed 10/22

5:30 am-10:45 am

1 stop4h 15m

$409

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Thu 12/25

2:57 pm-6:59 pm

1 stop5h 02m

Sioux Falls Joe Foss Field

Tue 12/30

6:17 am-2:27 pm

1 stop7h 10m

$417

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Tue 12/23

2:57 pm-6:59 pm

1 stop5h 02m

Sioux Falls Joe Foss Field

Wed 12/31

10:45 am-9:58 pm

2 stops10h 13m

$424

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 19 results
1
2

Best time to book a flight from Knoxville to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to South Dakota

What is the cheapest month to book a flight from Knoxville to South Dakota?

Currently, September is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $334). Flying from Knoxville to South Dakota in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SD?

Find hourly flight availability from Knoxville to South Dakota. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to South Dakota as you normally would.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated September 14, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to South Dakota have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,956 reviews

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,956 reviews
Delta
8.0
Very good
7,956 reviews

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,931 reviews
Delta
8.0
Very good
7,956 reviews

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,956 reviews

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to South Dakota?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to South Dakota.

  • How long is the flight from Knoxville to South Dakota?

    Delta, American Airlines, and Allegiant Air can get you from Knoxville to South Dakota in just under 5h 20m. Your travel time can differ by up to 15h 46m. The distance from Knoxville to South Dakota is about 1155 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Knoxville to South Dakota one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $186. However, be on the lookout for offers from Delta and Allegiant Air, as they are both options that can get you from Knoxville to South Dakota for a low price.

  • Can I find deals for flights from Knoxville to South Dakota that include hotel bookings?

    Yes. In addition to deals on Knoxville to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South Dakota.

  • Can I find deals for business class flights from Knoxville to South Dakota?

    Yes. Cheapflights offers flight deals from Knoxville to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to South Dakota?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $334). Flying from Knoxville to South Dakota in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to South Dakota

Discover the top 3 airlines that operate flights from Knoxville to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$436FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$283FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$297Average$486FlexibilityNo cancel feeOn-time69%

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