South Dakota

$193+ Cheap flights from Knoxville (TYS) to South Dakota

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FSD
abr. 23 — abr. 301
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Cheap flight deals from Knoxville to South Dakota

Cheapest flights from Knoxville to South Dakota
Explore the most affordable flight options available from Knoxville to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 24, 2026.

This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/294:09 pm
TYS
-
RAP
1 stop7h 49m
American Airlines
sáb. 5/26:00 am
RAP
-
TYS
1 stop7h 19m
American Airlines
Deal found 3/23$319
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/133:30 pm
TYS
-
FSD
1 stop5h 19m
Delta
dom. 5/175:20 am
FSD
-
TYS
1 stop6h 50m
Delta
Deal found 3/23$320
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/247:30 am
TYS
-
FSD
1 stop10h 51m
Allegiant Air
dom. 4/269:35 am
FSD
-
TYS
1 stop10h 39m
Allegiant Air
Deal found 3/19$324
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/136:30 am
TYS
-
FSD
2 stops9h 17m
American Airlines
dom. 5/176:00 am
FSD
-
TYS
1 stop5h 30m
American Airlines
Deal found 3/23$325
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/35:10 pm
TYS
-
FSD
1 stop6h 02m
Delta
mar. 4/144:17 pm
FSD
-
TYS
1 stop5h 42m
Delta
Deal found 3/20$334
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/48:48 am
TYS
-
RAP
1 stop5h 41m
United Airlines
mar. 8/1110:13 am
RAP
-
TYS
2 stops8h 15m
United Airlines
Deal found 3/23$344
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/18:30 am
TYS
-
FSD
1 stop25h 30m
Allegiant Air
lun. 4/1310:45 am
FSD
-
TYS
1 stop10h 03m
Allegiant Air
Deal found 3/20$349
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/74:30 pm
TYS
-
RAP
1 stop7h 58m
United Airlines
sáb. 4/112:47 pm
RAP
-
TYS
1 stop5h 42m
United Airlines
Deal found 3/23$349
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/308:58 am
TYS
-
FSD
1 stop9h 07m
Allegiant Air
lun. 4/1310:45 am
FSD
-
TYS
1 stop10h 03m
Allegiant Air
Deal found 3/20$358
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/316:35 am
TYS
-
FSD
1 stop4h 46m
Delta
sáb. 4/114:25 pm
FSD
-
TYS
1 stop5h 18m
Delta
Deal found 3/20$364
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/18:30 am
TYS
-
FSD
1 stop25h 30m
Allegiant Air
vie. 4/1010:45 am
FSD
-
TYS
1 stop10h 03m
Allegiant Air
Deal found 3/20$365
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/34:30 pm
TYS
-
RAP
1 stop6h 14m
United Airlines
mar. 4/72:47 pm
RAP
-
TYS
1 stop5h 42m
United Airlines
Deal found 3/19$369

Find flight deals from Knoxville to South Dakota

Keep the following information in mind while searching for Knoxville to South Dakota flight deals. Data was last updated marzo 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$319
(American Airlines)

One-way from

$193
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$293
Provider with most accurate pricing for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flights.
From Knoxville McGhee Tyson to South Dakota
One-way flight from Knoxville McGhee Tyson to South Dakota
Highest demand for flights based on searches. 22% potential increase in price ($112 potential increase over avg. RT price).
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 24, 2026.
Use the filters below to find and compare flights from Knoxville to South Dakota that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

mié. 5/20

4:09 pm-9:53 pm

1 stop6h 44m

Sioux Falls Joe Foss Field

dom. 5/24

5:35 pm-11:56 pm

1 stop5h 21m

$320

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

vie. 4/24

7:30 am-5:21 pm

1 stop10h 51m

Sioux Falls Joe Foss Field

dom. 4/26

9:35 am-9:14 pm

1 stop10h 39m

$324

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

vie. 4/24

3:58 pm-11:11 pm

2 stops8h 13m

Sioux Falls Joe Foss Field

dom. 4/26

6:00 am-12:30 pm

1 stop5h 30m

$334

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

mar. 4/7

10:49 am-7:02 pm

2 stops10h 13m

Rapid City

sáb. 4/11

5:27 am-3:06 pm

1 stop7h 39m

$354

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

vie. 4/3

4:30 pm-8:44 pm

1 stop6h 14m

Rapid City

mar. 4/7

2:47 pm-10:29 pm

1 stop5h 42m

$369

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

mar. 8/4

4:56 pm-10:33 pm

1 stop7h 37m

Rapid City

mar. 8/11

1:33 pm-8:48 pm

1 stop5h 15m

$370
Quickest round-trip

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

sáb. 6/27

5:57 pm-10:07 pm

1 stop5h 10m

Sioux Falls Joe Foss Field

sáb. 7/4

6:50 pm-12:35 am

1 stop4h 45m

$377

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

mié. 4/29

5:00 am-11:23 am

2 stops8h 23m

Rapid City

sáb. 5/2

6:00 am-3:19 pm

1 stop7h 19m

$384

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

sáb. 4/18

4:30 pm-9:04 pm

1 stop6h 34m

Rapid City

mar. 4/21

12:00 pm-10:29 pm

1 stop8h 29m

$409

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

vie. 4/3

4:30 pm-11:44 pm

1 stop8h 14m

Sioux Falls Joe Foss Field

mié. 4/8

6:00 am-3:06 pm

1 stop8h 06m

$419

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/19

Showing 1-10 of 25 resultsSorted by cheapest first
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3

Best time to book a flight from Knoxville to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to South Dakota

What is the cheapest month to book a flight from Knoxville to South Dakota?

Currently, September is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $233). Flying from Knoxville to South Dakota in June is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated marzo 24, 2026.
See what other customers who have flown with United Airlines and American Airlines from Knoxville to South Dakota have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.7

Entertainment

7.1

Crew

8.1

Comfort

7.3

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Boarding

7.7

Entertainment

7.1

Crew

8.1

Comfort

7.3

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Boarding

7.7

Entertainment

7.1

Crew

8.1

Comfort

7.3

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to South Dakota?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to South Dakota.

  • How long is the flight from Knoxville to South Dakota?

    American Airlines, Allegiant Air, and United Airlines can get you from Knoxville to South Dakota in just under 6h 44m. Your travel time can differ by up to 4h 07m. The distance from Knoxville to South Dakota is about 863 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to South Dakota that include hotel bookings?

    Yes. In addition to deals on Knoxville to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South Dakota.

  • Can I find deals for business class flights from Knoxville to South Dakota?

    Yes. Cheapflights offers flight deals from Knoxville to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to South Dakota?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $233). Flying from Knoxville to South Dakota in June is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to South Dakota

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Knoxville to South Dakota

Discover the top 2 airlines that operate flights from Knoxville to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$442FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$269Average$456FlexibilityNo cancel feeOn-time69%

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