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South Dakota

$269+ Cheap flights from Knoxville (TYS) to South Dakota

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FSD
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Knoxville to South Dakota

Cheapest flights from Knoxville to South Dakota
Explore the most affordable flight options available from Knoxville to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:08 pmTYS - FSD
1 stop18h 08mAmerican Airlines
Sat 1/37:10 pmFSD - TYS
1 stop14h 40mAmerican Airlines
Deal found 12/13$457
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:29 pmTYS - RAP
1 stop6h 51mAmerican Airlines
Mon 1/52:20 pmRAP - TYS
1 stop6h 01mAmerican Airlines
Deal found 12/14$618
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:23 pmTYS - RAP
2 stops18h 09mUnited Airlines
Mon 1/58:45 amRAP - TYS
2 stops11h 54mUnited Airlines
Deal found 12/13$621
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:45 amTYS - FSD
1 stop5h 07mUnited Airlines
Thu 1/13:08 pmFSD - TYS
1 stop6h 31mUnited Airlines
Deal found 12/12$800

Find flight deals from Knoxville to South Dakota

Keep the following information in mind while searching for Knoxville to South Dakota flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(United Airlines)

Popular in

June

Cheapest in

January

Average price

$368
Provider with most accurate pricing for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flights.
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From Knoxville McGhee Tyson to South Dakota
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Knoxville to South Dakota that are best for you.

Fly from

Knoxville

Fly to

South Dakota

Route

Depart

Return

Price

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Wed 1/28

11:10 am-5:18 pm

1 stop7h 08m

Sioux Falls Joe Foss Field

Wed 2/4

1:40 pm-10:31 pm

1 stop7h 51m

$269

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Fri 1/9

6:30 am-10:13 am

1 stop5h 43m

Rapid City

Fri 1/16

4:10 pm-11:09 pm

1 stop4h 59m

$279

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 1/9

4:25 pm-11:44 pm

1 stop8h 19m

Sioux Falls Joe Foss Field

Sun 1/11

7:30 am-1:24 pm

1 stop4h 54m

$339

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Fri 1/23

4:25 pm-8:32 pm

1 stop6h 07m

Rapid City

Tue 1/27

7:00 am-3:14 pm

1 stop6h 14m

$359

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Sat 12/20

5:08 pm-10:16 am

1 stop18h 08m

Sioux Falls Joe Foss Field

Sat 1/3

7:10 pm-10:50 am

1 stop14h 40m

$457

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Fri 1/9

6:59 am-3:22 pm

2 stops10h 23m

Rapid City

Fri 1/16

2:40 pm-1:24 pm

2 stops20h 44m

$463

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Tue 5/19

5:17 am-11:14 am

1 stop7h 57m

Rapid City

Fri 5/22

12:56 pm-9:12 pm

1 stop6h 16m

$541

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Best time to book a flight from Knoxville to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to South Dakota

What is the cheapest month to book a flight from Knoxville to South Dakota?

Currently, September is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $228). Flying from Knoxville to South Dakota in December is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SD?

Find hourly flight availability from Knoxville to South Dakota. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 48% on flights from Knoxville to South Dakota by exploring options for tickets in the evening.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated December 15, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to South Dakota have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to South Dakota?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to South Dakota.

  • How long is the flight from Knoxville to South Dakota?

    United Airlines and Delta can get you from Knoxville to South Dakota in just under 5h 43m. Your travel time can differ by up to 1h 25m. The distance from Knoxville to South Dakota is about 1155 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to South Dakota that include hotel bookings?

    Yes. In addition to deals on Knoxville to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South Dakota.

  • Can I find deals for business class flights from Knoxville to South Dakota?

    Yes. Cheapflights offers flight deals from Knoxville to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to South Dakota?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $228). Flying from Knoxville to South Dakota in December is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to South Dakota

Discover the top 3 airlines that operate flights from Knoxville to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$462FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$378FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$287Average$478FlexibilityNo cancel feeOn-time69%

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