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South Dakota

$249+ Cheap flights from Knoxville (TYS) to South Dakota

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FSD
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Knoxville to South Dakota

Cheapest flights from Knoxville to South Dakota
Explore the most affordable flight options available from Knoxville to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:24 amTYS - FSD
1 stop7h 58mAmerican Airlines
Sun 12/142:02 pmFSD - TYS
1 stop6h 38mAmerican Airlines
Deal found 10/27$249
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:57 pmTYS - FSD
2 stops8h 15mDelta
Sun 12/144:25 pmFSD - TYS
2 stops6h 03mDelta
Deal found 10/27$259
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:26 amTYS - FSD
1 stop7h 14mUnited Airlines
Sat 11/158:00 amFSD - TYS
1 stop4h 17mUnited Airlines
Deal found 10/29$279
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:50 amTYS - FSD
2 stops10h 33mUnited Airlines
Mon 11/171:47 pmFSD - TYS
2 stops8h 08mUnited Airlines
Deal found 10/28$289
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:55 pmTYS - RAP
1 stop7h 04mUnited Airlines
Sun 11/168:45 amRAP - TYS
1 stop5h 06mUnited Airlines
Deal found 10/28$289
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:13 pmTYS - FSD
1 stop15h 18mAllegiant Air
Sun 11/169:21 amFSD - TYS
1 stop12h 38mAllegiant Air
Deal found 10/28$298
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:52 pmTYS - FSD
1 stop4h 54mUnited Airlines
Sun 11/168:57 amFSD - TYS
1 stop5h 54mUnited Airlines
Deal found 10/27$306
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:24 amTYS - FSD
1 stop7h 59mAmerican Airlines
Sun 12/142:02 pmFSD - TYS
1 stop6h 38mAmerican Airlines
Deal found 10/27$319
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:30 amTYS - FSD
1 stop8h 01mMultiple Airlines
Sun 12/142:26 pmFSD - TYS
2 stops27h 48mMultiple Airlines
Deal found 10/27$322
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:29 amTYS - RAP
1 stop5h 53mDelta
Wed 12/106:05 amRAP - TYS
2 stops11h 55mDelta
Deal found 10/27$324
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/97:00 amTYS - FSD
1 stop7h 33mMultiple Airlines
Thu 11/139:21 amFSD - TYS
1 stop12h 38mMultiple Airlines
Deal found 10/27$327
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:37 pmTYS - RAP
2 stops10h 09mDelta
Tue 12/92:51 pmRAP - TYS
1 stop6h 27mDelta
Deal found 10/27$358

Cheap flight deals from Knoxville to South Dakota

Keep the following information in mind while searching for Knoxville to South Dakota flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

Popular in

June

Cheapest in

January

Average price

$470
Provider with most accurate pricing for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flights.
Search Deals
From Knoxville McGhee Tyson to South Dakota
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Knoxville to South Dakota that are best for you.

Fly from

Knoxville

Fly to

South Dakota

Route

Depart

Return

Price

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 12/12

3:57 pm-11:12 pm

2 stops8h 15m

Sioux Falls Joe Foss Field

Sun 12/14

4:25 pm-11:28 pm

2 stops6h 03m

$259

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Sat 1/24

6:19 am-10:13 am

1 stop5h 54m

Rapid City

Tue 1/27

4:10 pm-11:09 pm

1 stop4h 59m

$259

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Sat 2/21

6:45 am-10:05 am

1 stop5h 20m

Rapid City

Wed 2/25

4:00 pm-11:00 pm

1 stop5h 00m

$259

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Wed 4/15

6:45 am-12:28 pm

1 stop6h 43m

Sioux Falls Joe Foss Field

Sat 4/18

5:25 am-1:25 pm

1 stop7h 00m

$260

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Thu 11/13

10:50 am-8:23 pm

2 stops10h 33m

Sioux Falls Joe Foss Field

Mon 11/17

8:57 am-3:51 pm

1 stop5h 54m

$284

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Thu 11/13

1:52 pm-5:37 pm

1 stop4h 45m

Sioux Falls Joe Foss Field

Sat 11/15

8:57 am-8:33 pm

2 stops10h 36m

$284

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Thu 11/13

5:05 am-12:25 pm

2 stops8h 20m

Sioux Falls Joe Foss Field

Sat 11/15

1:03 pm-10:54 pm

2 stops8h 51m

$289

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

Wed 11/12

4:55 pm-9:59 pm

1 stop7h 04m

Rapid City

Sun 11/16

8:45 am-3:51 pm

1 stop5h 06m

$289

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Tue 12/16

4:22 pm-9:04 pm

1 stop5h 42m

Sioux Falls Joe Foss Field

Sat 12/20

6:00 am-3:39 pm

1 stop8h 39m

$306

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Best time to book a flight from Knoxville to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to South Dakota

What is the cheapest month to book a flight from Knoxville to South Dakota?

Currently, December is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $210). Flying from Knoxville to South Dakota in July is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SD?

Find hourly flight availability from Knoxville to South Dakota. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 48% on flights from Knoxville to South Dakota by exploring options for tickets in the evening.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated October 29, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to South Dakota have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to South Dakota?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to South Dakota.

  • How long is the flight from Knoxville to South Dakota?

    Delta can get you from Knoxville to South Dakota in just under 8h 15m. Your travel time can differ by up to . The distance from Knoxville to South Dakota is about 863 mi.

  • Can I find deals for flights from Knoxville to South Dakota that include hotel bookings?

    Yes. In addition to deals on Knoxville to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South Dakota.

  • Can I find deals for business class flights from Knoxville to South Dakota?

    Yes. Cheapflights offers flight deals from Knoxville to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to South Dakota?

    Currently, December is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $210). Flying from Knoxville to South Dakota in July is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to South Dakota

Discover the top 3 airlines that operate flights from Knoxville to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$462FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$358FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$322Average$488FlexibilityNo cancel feeOn-time69%

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