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South Dakota

$238+ Cheap flights from Knoxville (TYS) to South Dakota

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FSD
feb. 28 — mar. 71
sáb. 2/28
sáb. 3/7
1 adult, Economy
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Cheap flight deals from Knoxville to South Dakota

Cheapest flights from Knoxville to South Dakota
Explore the most affordable flight options available from Knoxville to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/75:44 am
TYS
-
FSD
1 stop8h 17m
American Airlines
sáb. 5/166:00 am
FSD
-
TYS
1 stop5h 30m
American Airlines
Deal found 1/27$294
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/116:30 am
TYS
-
RAP
1 stop5h 41m
Delta
dom. 2/154:29 pm
RAP
-
TYS
1 stop4h 43m
Delta
Deal found 1/27$309
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/307:00 am
TYS
-
RAP
1 stop5h 36m
United Airlines
mar. 5/57:00 am
RAP
-
TYS
1 stop5h 57m
United Airlines
Deal found 1/29$313
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/66:45 am
TYS
-
FSD
1 stop5h 02m
United Airlines
dom. 2/87:30 am
FSD
-
TYS
1 stop4h 54m
United Airlines
Deal found 1/28$339
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/126:35 am
TYS
-
RAP
1 stop5h 34m
Delta
lun. 2/164:29 pm
RAP
-
TYS
1 stop4h 43m
Delta
Deal found 1/28$344
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/36:30 am
TYS
-
RAP
1 stop5h 41m
Delta
mar. 2/104:10 pm
RAP
-
TYS
1 stop4h 59m
Delta
Deal found 1/27$354
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/252:05 pm
TYS
-
FSD
1 stop20h 16m
Multiple Airlines
lun. 3/309:01 pm
FSD
-
TYS
2 stops36h 35m
Multiple Airlines
Deal found 1/28$361
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/252:05 pm
TYS
-
FSD
1 stop20h 16m
Allegiant Air
lun. 3/3010:56 am
FSD
-
TYS
1 stop11h 36m
Allegiant Air
Deal found 1/28$362
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/305:00 am
TYS
-
RAP
2 stops8h 14m
American Airlines
mar. 5/511:44 am
RAP
-
TYS
2 stops10h 15m
American Airlines
Deal found 1/29$363
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/277:40 am
TYS
-
FSD
1 stop10h 25m
Multiple Airlines
lun. 3/309:01 pm
FSD
-
TYS
2 stops36h 35m
Multiple Airlines
Deal found 1/28$379
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/277:40 am
TYS
-
FSD
1 stop10h 25m
Allegiant Air
lun. 3/3010:56 am
FSD
-
TYS
1 stop11h 36m
Allegiant Air
Deal found 1/28$380
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/255:40 am
TYS
-
FSD
1 stop8h 01m
American Airlines
sáb. 3/281:26 pm
FSD
-
TYS
2 stops9h 24m
American Airlines
Deal found 1/28$382

Find flight deals from Knoxville to South Dakota

Keep the following information in mind while searching for Knoxville to South Dakota flight deals. Data was last updated enero 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$294
(American Airlines)

One-way from

$238
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$339
Provider with most accurate pricing for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flights.
Search Deals
From Knoxville McGhee Tyson to South Dakota
Search Deals
One-way flight from Knoxville McGhee Tyson to South Dakota
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($97 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
Use the filters below to find and compare flights from Knoxville to South Dakota that are best for you.

Fly from

Knoxville

Fly to

South Dakota

Route

Depart

Return

Price

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

vie. 5/8

4:09 pm-10:03 pm

1 stop6h 54m

Sioux Falls Joe Foss Field

sáb. 5/16

6:00 am-12:30 pm

1 stop5h 30m

$294

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

jue. 5/7

5:44 am-1:01 pm

1 stop8h 17m

Sioux Falls Joe Foss Field

sáb. 5/16

6:00 am-12:30 pm

1 stop5h 30m

$294

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

mié. 2/11

6:30 am-10:11 am

1 stop5h 41m

Rapid City

dom. 2/15

4:29 pm-11:12 pm

1 stop4h 43m

$309

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

jue. 2/12

6:35 am-10:09 am

1 stop5h 34m

Rapid City

lun. 2/16

4:29 pm-11:12 pm

1 stop4h 43m

$344

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

jue. 4/30

7:00 am-10:36 am

1 stop5h 36m

Rapid City

mar. 5/5

8:25 am-7:56 pm

2 stops9h 31m

$347

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

mié. 3/25

2:05 pm-9:21 am

1 stop20h 16m

Sioux Falls Joe Foss Field

lun. 3/30

9:01 pm-10:36 am

2 stops36h 35m

$361

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

mié. 3/25

2:05 pm-9:21 am

1 stop20h 16m

Sioux Falls Joe Foss Field

lun. 3/30

10:56 am-11:32 pm

1 stop11h 36m

$362

KnoxvilleRapid City

TYS - RAP

TYSRAP

Knoxville McGhee Tyson

jue. 4/30

5:00 am-11:14 am

2 stops8h 14m

Rapid City

mar. 5/5

11:44 am-11:59 pm

2 stops10h 15m

$363

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

mié. 3/25

5:40 am-12:41 pm

1 stop8h 01m

Sioux Falls Joe Foss Field

sáb. 3/28

1:26 pm-11:50 pm

2 stops9h 24m

$382

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

mié. 2/18

6:45 am-10:46 am

1 stop5h 01m

Sioux Falls Joe Foss Field

sáb. 2/21

3:15 pm-8:37 pm

1 stop4h 22m

$390

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 25 results
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Best time to book a flight from Knoxville to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to South Dakota

What is the cheapest month to book a flight from Knoxville to South Dakota?

Currently, September is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $228). Flying from Knoxville to South Dakota in June is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated enero 29, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to South Dakota have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,127 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,127 reviews
Delta
7.9
Good
8,127 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,214 reviews
Delta
7.9
Good
8,127 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,205 reviews
Delta
7.9
Good
8,127 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to South Dakota?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to South Dakota.

  • How long is the flight from Knoxville to South Dakota?

    American Airlines, Delta, and United Airlines can get you from Knoxville to South Dakota in just under 5h 36m. Your travel time can differ by up to 1h 18m. The distance from Knoxville to South Dakota is about 1155 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to South Dakota that include hotel bookings?

    Yes. In addition to deals on Knoxville to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South Dakota.

  • Can I find deals for business class flights from Knoxville to South Dakota?

    Yes. Cheapflights offers flight deals from Knoxville to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to South Dakota?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $228). Flying from Knoxville to South Dakota in June is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to South Dakota

Discover the top 3 airlines that operate flights from Knoxville to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$465FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$388FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$269Average$447FlexibilityNo cancel feeOn-time69%

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