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$160+ Cheap flights from Santiago de los Caballeros (STI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
STI — CHS
Jan 4 — Jan 111
Sun 1/4
Sun 1/11
1 adult, Economy
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Cheap flight deals from Santiago de los Caballeros to South Carolina

Cheapest flights from Santiago de los Caballeros to South Carolina
Explore the most affordable flight options available from Santiago de los Caballeros to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 5, 2025.

This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amSTI - CHS
2 stops17h 11mAmerican Airlines
Tue 1/67:42 pmCHS - STI
2 stops18h 50mAmerican Airlines
Deal found 12/4$324
This Priceline deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:43 amSTI - CLT
1 stop6h 56mMultiple Airlines
Mon 1/510:38 pmCLT - STI
1 stop15h 22mMultiple Airlines
Deal found 12/2$335
This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/223:43 amSTI - CLT
1 stop17h 50mSpirit Airlines
Sun 1/47:00 amCLT - STI
1 stop18h 42mSpirit Airlines
Deal found 12/4$350
This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/223:43 amSTI - CLT
1 stop20h 46mMultiple Airlines
Sun 1/42:22 pmCLT - STI
2 stops11h 20mMultiple Airlines
Deal found 12/4$382
This Priceline deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:43 amSTI - CLT
1 stop6h 56mMultiple Airlines
Mon 1/510:38 pmCLT - STI
1 stop15h 22mMultiple Airlines
Deal found 12/2$383
This Mytrip deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:43 amSTI - CLT
2 stops17h 56mSpirit Airlines
Mon 1/511:58 amCLT - STI
2 stops13h 44mSpirit Airlines
Deal found 12/2$413
This Mytrip deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:43 amSTI - CLT
1 stop6h 56mSpirit Airlines
Mon 1/511:58 amCLT - STI
3 stops13h 44mSpirit Airlines
Deal found 12/2$486
This Mytrip deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:43 amSTI - CHS
3 stops34h 27mSpirit Airlines
Tue 1/62:15 pmCHS - STI
2 stops11h 27mSpirit Airlines
Deal found 12/4$494

Find flight deals from Santiago de los Caballeros to South Carolina

Keep the following information in mind while searching for Santiago de los Caballeros to South Carolina flight deals. Data was last updated December 5, 2025.

Round-trip from

$335
(Priceline)

One-way from

$160
(Cheapflightsfares)
From Santiago de los Caballeros to South Carolina
Search Deals
One-way flight from Santiago de los Caballeros to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago de los Caballeros to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 5, 2025.
Use the filters below to find and compare flights from Santiago de los Caballeros to South Carolina that are best for you.

Fly from

Santiago de los Caballeros

Fly to

South Carolina

Route

Depart

Return

Price

Santiago de los CaballerosCharleston

STI - CHS

STICHS

Santiago de los Caballeros

Wed 12/31

6:00 am-10:11 pm

2 stops17h 11m

Charleston

Tue 1/6

7:42 pm-3:32 pm

2 stops18h 50m

$324

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Mon 12/29

3:43 am-9:39 am

1 stop6h 56m

Charlotte Douglas

Mon 1/5

10:38 pm-3:00 pm

1 stop15h 22m

$335

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Mon 12/22

3:43 am-8:33 pm

1 stop17h 50m

Charlotte Douglas

Sun 1/4

7:00 am-2:42 am

1 stop18h 42m

$350

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Mon 12/22

3:43 am-11:29 pm

1 stop20h 46m

Charlotte Douglas

Sun 1/4

2:22 pm-2:42 am

2 stops11h 20m

$382

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Tue 12/30

3:43 am-9:39 am

1 stop6h 56m

Charlotte Douglas

Mon 1/5

10:38 pm-3:00 pm

1 stop15h 22m

$383

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Mon 12/29

3:43 am-8:39 pm

2 stops17h 56m

Charlotte Douglas

Mon 1/5

11:58 am-2:42 am

2 stops13h 44m

$413

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Tue 12/30

3:43 am-9:39 am

1 stop6h 56m

Charlotte Douglas

Mon 1/5

11:58 am-2:42 am

3 stops13h 44m

$486

Santiago de los CaballerosCharleston

STI - CHS

STICHS

Santiago de los Caballeros

Tue 12/30

3:43 am-1:10 pm

3 stops34h 27m

Charleston

Tue 1/6

2:15 pm-2:42 am

2 stops11h 27m

$494

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Fri 2/6

12:52 pm-9:16 pm

1 stop9h 24m

Charlotte Douglas

Sun 2/8

7:01 am-2:53 pm

1 stop6h 52m

$500

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Thu 1/29

12:52 pm-9:16 pm

1 stop9h 24m

Charlotte Douglas

Mon 2/2

2:20 pm-11:51 pm

1 stop8h 31m

$500

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 21 results
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Best time to book a flight from Santiago de los Caballeros to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santiago de los Caballeros with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago de los Caballeros to South Carolina

What is the cheapest time of day to fly from STI to SC?

Find hourly flight availability from Santiago de los Caballeros to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 5, 2025.

When flying from Santiago de los Caballeros to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 26% versus a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Santiago de los Caballeros to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santiago de los Caballeros to South Carolina?

    If you book a flight to South Carolina from Santiago de los Caballeros, you will be flying from Santiago, which is the city’s only airport. Santiago de los Caballeros (STI) is located 6.8 mi from the center of Santiago de los Caballeros.

  • How long is the flight from Santiago de los Caballeros to South Carolina?

    There are many flights that can get you from Santiago de los Caballeros to South Carolina in 17h 11m. Fly via American Airlines or Spirit Airlines to get the fastest option. There are 1098 mi between Santiago de los Caballeros and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Santiago de los Caballeros to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santiago de los Caballeros to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago de los Caballeros to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago de los Caballeros to South Carolina.

  • Can I find deals for business class flights from Santiago de los Caballeros to South Carolina?

    Yes. Cheapflights offers flight deals from Santiago de los Caballeros to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Santiago de los Caballeros to South Carolina

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