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$170+ Cheap flights from Santiago de los Caballeros (STI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
STI — CHS
Feb 19 — Feb 261
Thu 2/19
Thu 2/26
1 adult, Economy
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Cheap flight deals from Santiago de los Caballeros to South Carolina

Cheapest flights from Santiago de los Caballeros to South Carolina
Explore the most affordable flight options available from Santiago de los Caballeros to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

This JetBlue deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:00 am
STI
-
CHS
1 stop10h 57m
JetBlue
Thu 4/3011:00 am
CHS
-
STI
1 stop11h 26m
JetBlue
Deal found 1/18$318
This Cheapflightsfares deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/253:43 pm
STI
-
CLT
1 stop8h 55m
Spirit Airlines
Tue 4/71:24 pm
CLT
-
STI
1 stop12h 25m
Spirit Airlines
Deal found 1/19$328
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:00 am
STI
-
CHS
1 stop27h 26m
American Airlines
Thu 2/268:25 pm
CHS
-
STI
2 stops16h 06m
American Airlines
Deal found 1/18$347
This JetBlue deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:15 am
STI
-
CHS
1 stop10h 24m
JetBlue
Thu 4/165:55 pm
CHS
-
STI
1 stop7h 40m
JetBlue
Deal found 1/18$356
This Cheapflightsfares deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/64:40 pm
STI
-
CLT
1 stop9h 00m
Spirit Airlines
Sun 2/86:00 am
CLT
-
STI
1 stop8h 33m
Spirit Airlines
Deal found 1/17$367
This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:15 pm
STI
-
CHS
1 stop16h 09m
Delta
Thu 4/306:30 am
CHS
-
STI
2 stops17h 44m
Delta
Deal found 1/18$392
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/131:32 pm
STI
-
CHS
2 stops22h 06m
American Airlines
Thu 4/166:20 pm
CHS
-
STI
2 stops18h 03m
American Airlines
Deal found 1/18$399
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/264:33 pm
STI
-
CHS
1 stop8h 25m
American Airlines
Mon 2/168:25 pm
CHS
-
STI
2 stops16h 06m
American Airlines
Deal found 1/18$411
This Faresmojo deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/279:00 am
STI
-
CHS
1 stop7h 35m
JetBlue
Wed 8/1911:00 am
CHS
-
STI
1 stop8h 34m
JetBlue
Deal found 1/18$427
This Expedia deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/279:00 am
STI
-
CHS
1 stop7h 35m
Multiple Airlines
Wed 8/197:00 am
CHS
-
STI
1 stop7h 35m
Multiple Airlines
Deal found 1/18$428
This Faresmojo deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/269:59 pm
STI
-
CHS
1 stop14h 21m
JetBlue
Mon 2/1612:02 pm
CHS
-
STI
1 stop12h 32m
JetBlue
Deal found 1/18$434
This WAYA deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:40 pm
STI
-
CLT
1 stop9h 00m
Spirit Airlines
Mon 5/46:00 am
CLT
-
STI
1 stop8h 35m
Spirit Airlines
Deal found 1/20$469

Find flight deals from Santiago de los Caballeros to South Carolina

Keep the following information in mind while searching for Santiago de los Caballeros to South Carolina flight deals. Data was last updated January 20, 2026.

Round-trip from

$318
(JetBlue)

One-way from

$170
(Trip.com)
From Santiago de los Caballeros to South Carolina
Search Deals
One-way flight from Santiago de los Caballeros to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago de los Caballeros to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Santiago de los Caballeros to South Carolina that are best for you.

Fly from

Santiago de los Caballeros

Fly to

South Carolina

Route

Depart

Return

Price

Santiago de los CaballerosCharleston

STI - CHS

STICHS

Santiago de los Caballeros

Mon 4/27

6:00 am-4:57 pm

1 stop10h 57m

Charleston

Thu 4/30

11:00 am-10:26 pm

1 stop11h 26m

$318

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Thu 3/26

3:43 pm-12:38 am

1 stop8h 55m

Charlotte Douglas

Tue 4/7

1:24 pm-1:49 am

1 stop12h 25m

$328

Santiago de los CaballerosCharleston

STI - CHS

STICHS

Santiago de los Caballeros

Mon 2/23

8:00 am-10:26 am

1 stop27h 26m

Charleston

Thu 2/26

8:25 pm-1:31 pm

2 stops16h 06m

$347

Santiago de los CaballerosCharleston

STI - CHS

STICHS

Santiago de los Caballeros

Mon 4/13

9:15 am-7:39 pm

1 stop10h 24m

Charleston

Thu 4/16

5:55 pm-1:35 am

1 stop7h 40m

$356

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Fri 2/6

4:40 pm-12:40 am

1 stop9h 00m

Charlotte Douglas

Sun 2/8

6:00 am-3:33 pm

1 stop8h 33m

$367

Santiago de los CaballerosCharleston

STI - CHS

STICHS

Santiago de los Caballeros

Mon 4/27

7:15 pm-11:24 am

1 stop16h 09m

Charleston

Thu 4/30

6:30 am-12:14 am

2 stops17h 44m

$392

Santiago de los CaballerosCharleston

STI - CHS

STICHS

Santiago de los Caballeros

Mon 4/13

1:32 pm-11:38 am

2 stops22h 06m

Charleston

Thu 4/16

6:20 pm-12:23 pm

2 stops18h 03m

$399

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Thu 4/30

3:40 pm-12:40 am

1 stop9h 00m

Charlotte Douglas

Mon 5/4

6:00 am-2:35 pm

1 stop8h 35m

$469

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Thu 4/30

6:10 am-9:42 pm

2 stops15h 32m

Charlotte Douglas

Mon 5/4

6:56 am-5:45 pm

2 stops10h 49m

$581

Santiago de los CaballerosCharlotte

STI - CLT

STICLT

Santiago de los Caballeros

Fri 4/17

6:10 am-9:42 pm

2 stops15h 32m

Charlotte Douglas

Sat 4/25

5:30 am-5:45 pm

2 stops12h 15m

$581

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 18 results
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Best time to book a flight from Santiago de los Caballeros to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santiago de los Caballeros with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago de los Caballeros to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Santiago de los Caballeros to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santiago de los Caballeros to South Carolina?

    If you book a flight to South Carolina from Santiago de los Caballeros, you will be flying from Santiago, which is the city’s only airport. Santiago de los Caballeros (STI) is located 6.8 mi from the center of Santiago de los Caballeros.

  • How long is the flight from Santiago de los Caballeros to South Carolina?

    There are many flights that can get you from Santiago de los Caballeros to South Carolina in 8h 55m. Fly via JetBlue, Spirit Airlines, or American Airlines to get the fastest option. There are 1261 mi between Santiago de los Caballeros and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Santiago de los Caballeros to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santiago de los Caballeros to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago de los Caballeros to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago de los Caballeros to South Carolina.

  • Can I find deals for business class flights from Santiago de los Caballeros to South Carolina?

    Yes. Cheapflights offers flight deals from Santiago de los Caballeros to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Santiago de los Caballeros to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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