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$511+ Cheap flights from Bruxelles-National (BRU) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — CHS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Bruxelles-National to South Carolina

Keep the following information in mind while searching for Bruxelles-National to South Carolina flight deals. Data was last updated September 15, 2025.

Round-trip from

$573
(AirNGo)

One-way from

$511
(Kiwi.com)
From Brussels Bruxelles-National to South Carolina
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One-way flight from Brussels Bruxelles-National to South Carolina
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Find flight deals from Bruxelles-National to South Carolina

Cheapest flights from Bruxelles-National to South Carolina
Explore the most affordable flight options available from Bruxelles-National to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This AirNGo deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2510:50 amBRU - CLT
2 stops16h 27mBritish Airways
Sat 10/118:20 pmCLT - BRU
1 stop12h 00mBritish Airways
Deal found 9/13$573
This Finnair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:15 amBRU - CLT
2 stops27h 25mMultiple Airlines
Fri 11/286:25 pmCLT - BRU
1 stop13h 15mMultiple Airlines
Deal found 9/14$576
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2010:15 amBRU - CLT
1 stop14h 40mAmerican Airlines
Fri 11/2810:55 pmCLT - BRU
1 stop12h 25mAmerican Airlines
Deal found 9/13$578
This AirNGo deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2510:50 amBRU - CLT
2 stops16h 27mBritish Airways
Sun 9/287:55 pmCLT - BRU
1 stop32h 10mBritish Airways
Deal found 9/14$579
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2510:50 amBRU - CLT
1 stop14h 10mAmerican Airlines
Sat 10/116:45 pmCLT - BRU
1 stop13h 35mAmerican Airlines
Deal found 9/14$580
This British Airways deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/259:35 pmBRU - CLT
1 stop28h 20mBritish Airways
Sun 11/26:25 pmCLT - BRU
1 stop19h 30mBritish Airways
Deal found 9/14$582
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2611:20 amBRU - CLT
2 stops27h 47mAmerican Airlines
Sun 11/211:39 amCLT - BRU
2 stops17h 11mAmerican Airlines
Deal found 9/14$585
This British Airways deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2812:00 pmBRU - CHS
2 stops16h 08mBritish Airways
Tue 11/47:12 pmCHS - BRU
2 stops15h 48mBritish Airways
Deal found 9/13$645
This lastminute.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2010:05 pmBRU - GSP
2 stops28h 55mBritish Airways
Sat 9/2712:59 pmGSP - BRU
2 stops38h 56mBritish Airways
Deal found 9/13$691
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/287:00 amBRU - CHS
2 stops17h 00mUnited Airlines
Tue 11/44:38 pmCHS - BRU
1 stop34h 17mUnited Airlines
Deal found 9/13$704
This Brussels Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2811:55 amBRU - CHS
1 stop12h 05mBrussels Airlines
Tue 11/42:52 pmCHS - BRU
1 stop10h 23mBrussels Airlines
Deal found 9/13$711
This Air Canada deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2810:00 amBRU - CHS
2 stops27h 56mMultiple Airlines
Tue 11/46:00 amCHS - BRU
3 stops19h 50mMultiple Airlines
Deal found 9/13$725

Cheapflights Fare Finder

 
Customize your flight search to find flights from Bruxelles-National to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to South Carolina that are best for you.

Fly from

Bruxelles-National

Fly to

South Carolina

Route

Depart

Return

Price

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Thu 9/25

10:50 am-9:17 pm

2 stops16h 27m

Charlotte Douglas

Sat 10/11

8:20 pm-2:20 pm

1 stop12h 00m

$573

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Thu 11/20

11:15 am-10:11 am

2 stops28h 56m

Charlotte Douglas

Fri 11/28

8:20 pm-3:25 pm

1 stop13h 05m

$576

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Mon 10/27

5:30 pm-2:55 pm

1 stop26h 25m

Charlotte Douglas

Sun 11/2

11:39 am-10:50 am

2 stops17h 11m

$579

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Thu 9/25

10:50 am-7:00 pm

1 stop14h 10m

Charlotte Douglas

Sat 10/11

6:00 pm-2:20 pm

2 stops14h 20m

$579

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Thu 9/25

10:50 am-9:17 pm

2 stops16h 27m

Charlotte Douglas

Sun 9/28

7:55 pm-10:05 am

1 stop32h 10m

$579

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Sun 10/26

11:20 am-7:55 pm

1 stop13h 35m

Charlotte Douglas

Sun 11/2

11:39 am-10:50 am

2 stops17h 11m

$579

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Sun 10/26

5:30 pm-3:00 pm

1 stop26h 30m

Charlotte Douglas

Sun 11/2

10:55 pm-1:55 pm

1 stop33h 00m

$582

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Mon 10/27

5:30 pm-7:50 pm

1 stop31h 20m

Charlotte Douglas

Sun 11/2

10:55 pm-11:10 am

1 stop30h 15m

$582

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Sat 10/25

9:35 pm-7:55 pm

1 stop28h 20m

Charlotte Douglas

Sun 11/2

6:25 pm-7:55 pm

1 stop19h 30m

$582

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Wed 10/29

8:30 pm-7:55 pm

1 stop28h 25m

Charlotte Douglas

Sun 11/2

10:55 pm-1:55 pm

1 stop33h 00m

$582

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 32 results
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Best time to book a flight from Bruxelles-National to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Bruxelles-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Brussels Bruxelles-National Airport to South Carolina

What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to South Carolina (average of $217). Flying from Brussels Bruxelles-National Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Brussels Bruxelles-National Airport to South Carolina?

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Brussels Bruxelles-National Airport to South Carolina?

    Departing from Brussels Bruxelles-National Airport to South Carolina will take you 16h 27m. The distance between Brussels Bruxelles-National Airport and South Carolina is about 4194 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Brussels Bruxelles-National Airport to South Carolina?

    The most popular route from Brussels Bruxelles-National Airport to South Carolina is Brussels Bruxelles-National - Charlotte Douglas. You may also consider Brussels Bruxelles-National - Greenville or Brussels Bruxelles-National - Columbia Metropolitan.

  • Can I find deals for flights from Bruxelles-National to South Carolina that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to South Carolina.

  • Can I find deals for business class flights from Bruxelles-National to South Carolina?

    Yes. Cheapflights offers flight deals from Bruxelles-National to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to South Carolina (average of $217). Flying from Brussels Bruxelles-National Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Bruxelles-National to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Charleroi Brussels to Boston flights
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Charleroi Brussels to Dulles Intl flights
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