$157+ Cheap flights from Guatemala to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
GUA — CHS
Mar 29 — Apr 51
1 adult, Economy
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Find cheap flights from Guatemala to South Carolina with Cheapflights
1. Tell us where you want to go
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Cheapest flights from Guatemala to South CarolinaExplore the most affordable flight options available from Guatemala to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.
Explore the most affordable flight options available from Guatemala to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.
This Priceline deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:15 pm
GUA
- CLT
1 stop8h 18m
Spirit Airlines
Sun 5/179:24 pm
CLT
- GUA
1 stop15h 56m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$236
This Priceline deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:15 pm
GUA
- CLT
1 stop8h 18m
Spirit Airlines
Sat 5/96:00 am
CLT
- GUA
1 stop7h 20m
Spirit Airlines
Deal found 2/22![Spirit Airlines logo]()
$252
This Priceline deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:15 pm
GUA
- CLT
1 stop8h 18m
Spirit Airlines
Wed 5/206:00 am
CLT
- GUA
1 stop7h 20m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$254
This Expedia deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:38 pm
GUA
- CLT
1 stop27h 47m
Multiple Airlines
Thu 4/169:24 pm
CLT
- GUA
1 stop15h 56m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1912:23 pm
GUA
- CLT
1 stop10h 15m
Spirit Airlines
Sat 4/116:00 am
CLT
- GUA
1 stop7h 14m
Spirit Airlines
Deal found 2/22![Spirit Airlines logo]()
$281
This CheapOair deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1912:23 pm
GUA
- CLT
1 stop10h 15m
Spirit Airlines
Mon 3/231:20 pm
CLT
- GUA
1 stop12h 44m
Spirit Airlines
Deal found 2/22![Spirit Airlines logo]()
$282
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:15 pm
GUA
- CLT
1 stop8h 18m
Spirit Airlines
Fri 5/16:30 am
CLT
- GUA
1 stop5h 43m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:16 am
GUA
- CLT
2 stops21h 01m
Spirit Airlines
Sat 5/26:00 am
CLT
- GUA
1 stop7h 20m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/198:25 am
GUA
- CLT
2 stops23h 22m
Multiple Airlines
Sat 4/116:00 am
CLT
- GUA
1 stop28h 28m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$294
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2312:58 am
GUA
- CLT
1 stop11h 04m
Spirit Airlines
Tue 9/86:00 am
CLT
- GUA
1 stop7h 00m
Spirit Airlines
Deal found 2/22![Spirit Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/41:28 pm
GUA
- GSP
1 stop25h 23m
Multiple Airlines
Thu 3/269:46 pm
GSP
- GUA
1 stop28h 18m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/41:28 pm
GUA
- GSP
1 stop25h 23m
Multiple Airlines
Sun 3/229:46 pm
GSP
- GUA
1 stop28h 18m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$323
Best flights from Guatemala to South CarolinaDiscover carefully curated flight deals from Guatemala to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 27, 2026.
Discover carefully curated flight deals from Guatemala to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:15 pm
GUA
- CLT
2 stops18h 55m
Spirit Airlines
Sat 5/96:00 am
CLT
- GUA
1 stop7h 20m
Spirit Airlines
Deal found 2/22![Spirit Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1212:59 am
GUA
- CAE
1 stop14h 53m
Multiple Airlines
Fri 4/176:42 pm
CAE
- GUA
1 stop18h 38m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:27 pm
GUA
- CLT
1 stop7h 12m
United Airlines
Tue 9/2211:45 am
CLT
- GUA
1 stop6h 47m
United Airlines
Deal found 2/26![United Airlines logo]()
$412
This CheapOair deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1912:23 pm
GUA
- CLT
1 stop10h 15m
Spirit Airlines
Mon 3/231:20 pm
CLT
- GUA
1 stop12h 44m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:56 pm
GUA
- CAE
1 stop8h 46m
Delta
Tue 9/225:40 am
CAE
- GUA
1 stop7h 50m
Delta
Deal found 2/23![Delta logo]()
$658
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:46 pm
GUA
- CAE
1 stop20h 12m
American Airlines
Tue 5/197:22 pm
CAE
- GUA
2 stops18h 28m
American Airlines
Deal found 2/26![American Airlines logo]()
$671
This FlightHub deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:13 pm
GUA
- CHS
2 stops19h 01m
JetBlue
Wed 4/1511:18 am
CHS
- GUA
2 stops27h 17m
JetBlue
Deal found 2/25![JetBlue logo]()
$753
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1011:28 am
GUA
- MYR
2 stops51h 40m
Multiple Airlines
Fri 4/177:51 pm
MYR
- GUA
1 stop17h 29m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:15 am
GUA
- CLT
1 stop13h 24m
United Airlines
Tue 9/226:30 am
CLT
- GUA
1 stop7h 06m
United Airlines
Deal found 2/24![United Airlines logo]()
$412
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/41:28 pm
GUA
- CLT
2 stops19h 49m
Multiple Airlines
Sun 3/157:00 am
CLT
- GUA
3 stops28h 00m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:27 pm
GUA
- CLT
1 stop7h 12m
United Airlines
Thu 9/246:30 am
CLT
- GUA
1 stop7h 06m
United Airlines
Deal found 2/24![United Airlines logo]()
$412
This CheapOair deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/11:28 pm
GUA
- MYR
1 stop17h 45m
Spirit Airlines
Tue 3/39:09 am
MYR
- GUA
1 stop28h 15m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$453
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1912:23 pm
GUA
- CLT
2 stops19h 48m
Multiple Airlines
Sat 4/117:00 am
CLT
- GUA
3 stops18h 10m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:15 am
GUA
- CLT
1 stop13h 24m
United Airlines
Tue 9/2211:45 am
CLT
- GUA
1 stop9h 04m
United Airlines
Deal found 2/24![United Airlines logo]()
$434
This KAYAK deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:37 am
GUA
- CAE
1 stop11h 37m
GOL
Fri 4/37:26 pm
CAE
- GUA
2 stops19h 37m
GOL
Deal found 2/25![GOL logo]()
$1,085
This KAYAK deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:07 pm
GUA
- CAE
1 stop6h 13m
LATAM Airlines
Fri 4/35:34 am
CAE
- GUA
1 stop8h 03m
LATAM Airlines
Deal found 2/25![LATAM Airlines logo]()
$1,110
This OneTravel deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:59 am
GUA
- MYR
2 stops17h 49m
Spirit Airlines
Fri 4/177:51 pm
MYR
- GUA
2 stops16h 22m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:27 pm
GUA
- CLT
1 stop7h 32m
United Airlines
Sun 9/206:30 am
CLT
- GUA
1 stop7h 06m
United Airlines
Deal found 2/24![United Airlines logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:09 am
GUA
- CHS
2 stops33h 31m
Multiple Airlines
Fri 5/297:00 am
CHS
- GUA
1 stop6h 20m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:15 am
GUA
- CLT
1 stop13h 44m
United Airlines
Thu 9/246:30 am
CLT
- GUA
1 stop14h 19m
United Airlines
Deal found 2/24![United Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:43 am
GUA
- GSP
1 stop11h 13m
American Airlines
Thu 4/305:20 am
GSP
- GUA
2 stops10h 42m
American Airlines
Deal found 2/24![American Airlines logo]()
$691
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:07 pm
GUA
- GSP
1 stop8h 47m
Delta
Sun 4/55:40 am
GSP
- GUA
1 stop7h 57m
Delta
Deal found 2/23![Delta logo]()
$722
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:37 am
GUA
- GSP
1 stop7h 59m
American Airlines
Thu 4/306:00 am
GSP
- GUA
1 stop7h 50m
American Airlines
Deal found 2/24![American Airlines logo]()
$717
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2612:23 pm
GUA
- SAV
1 stop26h 47m
Multiple Airlines
Mon 4/612:51 pm
SAV
- GUA
2 stops45h 06m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$546
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:26 pm
GUA
- CAE
1 stop16h 49m
Delta
Wed 9/235:40 am
CAE
- GUA
1 stop7h 50m
Delta
Deal found 2/23![Delta logo]()
$765
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/51:43 pm
GUA
- GSP
1 stop9h 39m
American Airlines
Mon 3/237:26 pm
GSP
- GUA
1 stop20h 41m
American Airlines
Deal found 2/25![American Airlines logo]()
$724
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/62:09 pm
GUA
- GSP
1 stop8h 34m
Delta
Tue 3/245:40 am
GSP
- GUA
1 stop7h 57m
Delta
Deal found 2/23![Delta logo]()
$771
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:37 am
GUA
- GSP
1 stop15h 03m
American Airlines
Wed 3/257:26 pm
GSP
- GUA
1 stop20h 41m
American Airlines
Deal found 2/24![American Airlines logo]()
$724
This Mytrip deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:15 pm
GUA
- CHS
3 stops24h 16m
Spirit Airlines
Fri 7/317:00 am
CHS
- GUA
3 stops29h 11m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$743
This Faresmojo deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/297:10 pm
GUA
- SAV
1 stop18h 15m
Multiple Airlines
Sun 4/56:19 pm
SAV
- GUA
1 stop13h 41m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$634
Last-minute flights from Guatemala to South CarolinaDiscover last-minute flight deals from Guatemala to South Carolina. Data last updated February 27, 2026 and is based on user searches.
Discover last-minute flight deals from Guatemala to South Carolina. Data last updated February 27, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:28 pm
GUA
- CHS
1 stop27h 12m
Spirit Airlines
Mon 3/26:35 pm
CHS
- GUA
1 stop18h 49m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$452
This eDestinos deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/281:28 pm
GUA
- CLT
1 stop9h 28m
Spirit Airlines
Mon 3/161:20 pm
CLT
- GUA
1 stop12h 44m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$428
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2812:15 pm
GUA
- CLT
1 stop19h 28m
Multiple Airlines
Thu 4/309:24 pm
CLT
- GUA
1 stop15h 56m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$439
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:15 pm
GUA
- CLT
1 stop21h 02m
Multiple Airlines
Mon 3/168:56 am
CLT
- GUA
1 stop17h 08m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/41:28 pm
GUA
- GSP
1 stop25h 23m
Multiple Airlines
Thu 3/269:46 pm
GSP
- GUA
1 stop28h 18m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/41:28 pm
GUA
- GSP
1 stop25h 23m
Multiple Airlines
Sun 3/229:46 pm
GSP
- GUA
1 stop28h 18m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/51:28 pm
GUA
- GSP
2 stops29h 10m
Multiple Airlines
Mon 3/234:28 pm
GSP
- GUA
1 stop9h 36m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:28 pm
GUA
- CLT
1 stop17h 58m
Multiple Airlines
Fri 3/209:32 pm
CLT
- GUA
2 stops27h 18m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:28 pm
GUA
- CHS
1 stop27h 12m
Spirit Airlines
Fri 5/297:00 am
CHS
- GUA
1 stop6h 20m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$424
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1312:59 am
GUA
- CLT
1 stop17h 18m
Spirit Airlines
Tue 3/179:00 pm
CLT
- GUA
1 stop16h 24m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:55 am
GUA
- CLT
2 stops46h 17m
Multiple Airlines
Tue 3/179:00 pm
CLT
- GUA
1 stop16h 24m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$416
This CheapOair deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1912:23 pm
GUA
- CLT
1 stop10h 15m
Spirit Airlines
Mon 3/231:20 pm
CLT
- GUA
1 stop12h 44m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$328
One-way flights from Guatemala to South CarolinaSearch for one-way flight options from Guatemala to South Carolina. Find affordable one-way fares based on user searches. Data last updated February 27, 2026.
Search for one-way flight options from Guatemala to South Carolina. Find affordable one-way fares based on user searches. Data last updated February 27, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:28 pm
GUA
- CLT
1 stop9h 28m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1112:28 pm
GUA
- CLT
1 stop17h 53m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$163
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:23 pm
GUA
- CLT
1 stop10h 15m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$172
This Cheapflightsfares deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:59 am
GUA
- CLT
1 stop17h 18m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:59 am
GUA
- CLT
1 stop17h 18m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1612:59 am
GUA
- SAV
3 stops36h 56m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/512:15 pm
GUA
- CLT
1 stop21h 02m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$200
This eDestinos deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/128:25 am
GUA
- CLT
2 stops23h 47m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$202
This OneTravel deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1612:23 pm
GUA
- CLT
1 stop17h 58m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1612:59 am
GUA
- SAV
2 stops36h 56m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/51:28 pm
GUA
- MYR
1 stop17h 45m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/51:28 pm
GUA
- MYR
2 stops19h 32m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$246
Find flight deals from Guatemala to South Carolina
Keep the following information in mind while searching for Guatemala to South Carolina flight deals. Data was last updated February 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $236 (Priceline) |
One-way from | $157 (Cheapflightsfares) |
Popular in | November |
Cheapest in | May |
Cheapflights Fare Finder
Customize your flight search to find flights from Guatemala to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Guatemala to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Guatemala CityCharlotte
GUA - CLT
GUACLT
Guatemala City La Aurora
Thu 4/23
12:15 pm-9:10 am
2 stops18h 55m
Charlotte Douglas
Sat 5/9
6:00 am-11:20 am
1 stop7h 20m
$313
Guatemala CityCharlotte
GUA - CLT
GUACLT
Guatemala City La Aurora
Thu 3/19
12:23 pm-12:38 am
1 stop10h 15m
Charlotte Douglas
Mon 3/23
1:20 pm-12:04 am
1 stop12h 44m
$328
Guatemala CityColumbia
GUA - CAE
GUACAE
Guatemala City La Aurora
Sun 4/12
12:59 am-5:52 pm
1 stop14h 53m
Columbia Metropolitan
Fri 4/17
6:42 pm-11:20 am
1 stop18h 38m
$372
Guatemala CityMyrtle Beach
GUA - MYR
GUAMYR
Guatemala City La Aurora
Fri 4/10
11:28 am-5:08 pm
2 stops51h 40m
Myrtle Beach Intl
Fri 4/17
7:51 pm-11:20 am
1 stop17h 29m
$394
Guatemala CityCharlotte
GUA - CLT
GUACLT
Guatemala City La Aurora
Wed 3/4
1:28 pm-10:17 am
2 stops19h 49m
Charlotte Douglas
Sun 3/15
7:00 am-9:00 am
3 stops28h 00m
$395
Guatemala CityCharlotte
GUA - CLT
GUACLT
Guatemala City La Aurora
Tue 5/19
12:27 pm-9:39 pm
1 stop7h 12m
Charlotte Douglas
Tue 9/22
11:45 am-4:32 pm
1 stop6h 47m
$412
Guatemala CityCharlotte
GUA - CLT
GUACLT
Guatemala City La Aurora
Mon 5/18
6:15 am-9:39 pm
1 stop13h 24m
Charlotte Douglas
Tue 9/22
6:30 am-11:36 am
1 stop7h 06m
$412
Guatemala CityCharlotte
GUA - CLT
GUACLT
Guatemala City La Aurora
Tue 5/19
12:27 pm-9:39 pm
1 stop7h 12m
Charlotte Douglas
Thu 9/24
6:30 am-11:36 am
1 stop7h 06m
$412
Guatemala CityCharlotte
GUA - CLT
GUACLT
Guatemala City La Aurora
Thu 3/19
12:23 pm-10:11 am
2 stops19h 48m
Charlotte Douglas
Sat 4/11
7:00 am-11:10 pm
3 stops18h 10m
$422
Guatemala CityCharlotte
GUA - CLT
GUACLT
Guatemala City La Aurora
Sat 5/16
6:15 am-9:39 pm
1 stop13h 24m
Charlotte Douglas
Tue 9/22
11:45 am-6:49 pm
1 stop9h 04m
$434
Showing 1-10 of 56 resultsSorted by cheapest first
Best time to book a flight from Guatemala to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guatemala with our price prediction graph.
GUA-CLT
GUA-CAE
GUA-CHS
GUA-MYR
GUA-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guatemala to South Carolina
GT0-USSC
GUA-CLT
GUA-CAE
GUA-CHS
GUA-MYR
What is the cheapest month to book a flight from Guatemala to South Carolina?
Currently, November is the cheapest month in which you can book a flight from Guatemala to South Carolina (average of $195). Flying from Guatemala to South Carolina in August is currently the most expensive (average of $543). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 27, 2026.
Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Guatemala to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Guatemala to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Guatemala to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Guatemala to South Carolina by cabin class
Find flights from Guatemala to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Guatemala and South Carolina flights
Browse other Guatemala and South Carolina flight options. Last updated on February 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Guatemala after your stay in South Carolina
Guatemala to South Carolina flights
Consider these flights traveling from Guatemala to South Carolina.
Top 3 airlines flying from Guatemala to South Carolina
Discover the top 3 airlines that operate flights from Guatemala to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$270 | Average$299 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$371 | Average$466 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$547 | Average$694 | FlexibilityNo cancel fee | On-timeN/A |