How long is the flight from Guatemala to South Carolina?

Departing from Guatemala to South Carolina will take you 7h 59m. The distance between Guatemala and South Carolina is about 1425 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Can I find deals for flights from Guatemala to South Carolina that include hotel bookings?

Yes. In addition to deals on Guatemala to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Guatemala to South Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guatemala to South Carolina.

Can I find deals for business class flights from Guatemala to South Carolina?

Yes. Cheapflights offers flight deals from Guatemala to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$140+ Flights from Guatemala to South Carolina

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Cheap flight deals from Guatemala to South Carolina

Cheapest flights from Guatemala to South Carolina
Explore the most affordable flight options available from Guatemala to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Mon 12/2910:53 amGUA - CLT

1 stop28h 45mMultiple Airlines

Wed 12/312:57 pmCLT - GUA

1 stop19h 41mMultiple Airlines

Deal found 12/23

$378

Tue 12/301:39 pmGUA - CLT

1 stop8h 50mSpirit Airlines

Mon 1/267:43 pmCLT - GUA

2 stops16h 37mSpirit Airlines

Deal found 12/26

$381

Tue 12/307:51 pmGUA - CLT

1 stop23h 18mMultiple Airlines

Tue 1/65:14 pmCLT - GUA

2 stops41h 00mMultiple Airlines

Deal found 12/23

$390

Thu 12/253:00 pmGUA - CLT

1 stop21h 56mMultiple Airlines

Tue 12/307:46 pmCLT - GUA

1 stop14h 52mMultiple Airlines

Deal found 12/23

$404

Mon 12/291:39 pmGUA - CHS

1 stop6h 44mSpirit Airlines

Sat 1/106:35 pmCHS - GUA

1 stop18h 54mSpirit Airlines

Deal found 12/24

$415

Tue 12/301:39 pmGUA - CLT

1 stop8h 50mSpirit Airlines

Tue 1/69:34 pmCLT - GUA

1 stop14h 51mSpirit Airlines

Deal found 12/23

$419

Mon 12/291:39 pmGUA - CLT

1 stop8h 50mMultiple Airlines

Tue 12/307:46 pmCLT - GUA

1 stop14h 52mMultiple Airlines

Deal found 12/23

$422

Tue 12/307:45 amGUA - CLT

2 stops11h 24mMultiple Airlines

Mon 1/267:00 amCLT - GUA

2 stops17h 10mMultiple Airlines

Deal found 12/26

$425

Tue 12/301:39 pmGUA - CLT

1 stop8h 50mSpirit Airlines

Sun 1/49:34 pmCLT - GUA

1 stop14h 51mSpirit Airlines

Deal found 12/25

$430

Fri 12/261:39 pmGUA - CLT

1 stop8h 50mMultiple Airlines

Tue 12/307:46 pmCLT - GUA

1 stop14h 52mMultiple Airlines

Deal found 12/23

$447

Sun 12/281:39 pmGUA - CLT

1 stop8h 50mMultiple Airlines

Tue 12/307:46 pmCLT - GUA

1 stop14h 52mMultiple Airlines

Deal found 12/23

$455

Thu 12/255:45 amGUA - CHS

2 stops14h 38mMultiple Airlines

Thu 1/110:18 pmCHS - GUA

1 stop15h 16mMultiple Airlines

Deal found 12/24

$555

Best flights from Guatemala to South Carolina
Discover carefully curated flight deals from Guatemala to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 26, 2025.

Wed 1/285:10 amGUA - CLT

2 stops27h 45mMultiple Airlines

Fri 2/69:59 pmCLT - GUA

1 stop14h 21mMultiple Airlines

Deal found 12/24

$281

Tue 2/171:29 pmGUA - CLT

1 stop17h 57mSpirit Airlines

Thu 2/266:01 pmCLT - GUA

1 stop18h 19mSpirit Airlines

Deal found 12/24

$284

Sat 3/712:05 amGUA - CHS

1 stop7h 59mUnited Airlines

Tue 3/176:40 amCHS - GUA

1 stop11h 45mUnited Airlines

Deal found 12/24

$377

Sat 1/244:40 pmGUA - SAV

2 stops18h 29mJetBlue

Sat 1/318:25 pmSAV - GUA

2 stops17h 36mJetBlue

Deal found 12/25

$486

Thu 2/1912:15 pmGUA - CLT

1 stop21h 02mSpirit Airlines

Thu 2/267:05 pmCLT - GUA

2 stops17h 15mSpirit Airlines

Deal found 12/24

$291

Sat 1/247:00 amGUA - GSP

2 stops15h 59mAmerican Airlines

Tue 1/277:42 pmGSP - GUA

2 stops18h 31mAmerican Airlines

Deal found 12/23

$606

Wed 2/181:29 pmGUA - CLT

1 stop9h 27mSpirit Airlines

Mon 3/25:55 amCLT - GUA

1 stop7h 29mSpirit Airlines

Deal found 12/25

$304

Sat 1/241:28 pmGUA - SAV

1 stop26h 37mMultiple Airlines

Sat 1/3111:49 amSAV - GUA

2 stops24h 31mMultiple Airlines

Deal found 12/25

$355

Mon 3/910:59 pmGUA - CHS

1 stop8h 16mUnited Airlines

Tue 3/176:40 amCHS - GUA

1 stop11h 45mUnited Airlines

Deal found 12/24

$377

Wed 1/2812:15 pmGUA - CLT

2 stops11h 25mSpirit Airlines

Fri 2/61:24 pmCLT - GUA

2 stops22h 56mSpirit Airlines

Deal found 12/24

$324

Mon 3/912:05 amGUA - CHS

1 stop12h 49mUnited Airlines

Tue 3/176:40 amCHS - GUA

1 stop6h 46mUnited Airlines

Deal found 12/24

$377

Sat 3/712:05 amGUA - CHS

1 stop7h 59mUnited Airlines

Wed 3/1810:20 amCHS - GUA

1 stop12h 05mUnited Airlines

Deal found 12/24

$377

Sat 1/314:40 pmGUA - SAV

1 stop25h 48mJetBlue

Tue 2/178:50 pmSAV - GUA

1 stop20h 52mJetBlue

Deal found 12/25

$492

Wed 3/1112:05 amGUA - CHS

1 stop12h 49mUnited Airlines

Wed 3/1810:20 amCHS - GUA

1 stop12h 05mUnited Airlines

Deal found 12/24

$377

Wed 3/1112:05 amGUA - CHS

1 stop7h 59mUnited Airlines

Tue 3/176:40 amCHS - GUA

1 stop11h 45mUnited Airlines

Deal found 12/24

$377

Sat 1/314:02 pmGUA - SAV

2 stops17h 37mAmerican Airlines

Tue 2/177:15 pmSAV - GUA

2 stops18h 28mAmerican Airlines

Deal found 12/25

$623

Mon 3/912:05 amGUA - CHS

1 stop7h 59mUnited Airlines

Thu 3/195:06 pmCHS - GUA

1 stop20h 20mUnited Airlines

Deal found 12/24

$393

Sat 1/314:40 pmGUA - SAV

1 stop25h 48mJetBlue

Mon 2/168:55 pmSAV - GUA

1 stop20h 42mJetBlue

Deal found 12/24

$595

Sat 3/712:05 amGUA - CHS

1 stop12h 49mUnited Airlines

Thu 3/195:06 pmCHS - GUA

1 stop20h 20mUnited Airlines

Deal found 12/24

$393

Fri 1/234:02 pmGUA - CAE

2 stops16h 40mAmerican Airlines

Tue 1/277:08 amCAE - GUA

1 stop7h 59mAmerican Airlines

Deal found 12/25

$675

Wed 3/1112:05 amGUA - CHS

1 stop12h 49mUnited Airlines

Sat 3/215:06 pmCHS - GUA

1 stop25h 19mUnited Airlines

Deal found 12/24

$393

Thu 1/2211:59 pmGUA - CHS

1 stop8h 51mUnited Airlines

Mon 1/265:13 pmCHS - GUA

1 stop23h 22mUnited Airlines

Deal found 12/23

$394

Thu 1/222:10 amGUA - CHS

1 stop18h 47mUnited Airlines

Mon 1/265:13 pmCHS - GUA

1 stop20h 13mUnited Airlines

Deal found 12/24

$396

Tue 1/138:20 amGUA - CAE

2 stops13h 36mAmerican Airlines

Wed 1/211:09 pmCAE - GUA

1 stop11h 20mAmerican Airlines

Deal found 12/25

$817

Tue 12/301:50 pmGUA - CAE

2 stops17h 49mAmerican Airlines

Tue 1/611:24 amCAE - GUA

2 stops10h 22mAmerican Airlines

Deal found 12/25

$829

Wed 12/316:39 amGUA - CAE

1 stop11h 37mAmerican Airlines

Tue 1/65:31 amCAE - GUA

2 stops10h 20mAmerican Airlines

Deal found 12/25

$989

Fri 1/232:10 amGUA - GSP

1 stop12h 25mUnited Airlines

Tue 1/276:49 amGSP - GUA

1 stop6h 37mUnited Airlines

Deal found 12/23

$591

Thu 1/221:28 pmGUA - GSP

1 stop7h 29mUnited Airlines

Mon 1/264:50 pmGSP - GUA

1 stop27h 49mUnited Airlines

Deal found 12/23

$596

Tue 12/303:10 pmGUA - CAE

1 stop7h 58mAmerican Airlines

Thu 1/13:37 pmCAE - GUA

1 stop9h 19mAmerican Airlines

Deal found 12/26

$1,074

Thu 1/2911:59 pmGUA - GSP

1 stop10h 09mUnited Airlines

Mon 2/26:49 amGSP - GUA

1 stop6h 37mUnited Airlines

Deal found 12/24

$655

Last-minute flights from Guatemala to South Carolina
Discover last-minute flight deals from Guatemala to South Carolina. Data last updated December 26, 2025 and is based on user searches.

Mon 12/291:39 pmGUA - CHS

1 stop6h 44mSpirit Airlines

Sat 1/106:35 pmCHS - GUA

1 stop18h 54mSpirit Airlines

Deal found 12/24

$415

Wed 1/147:45 amGUA - CLT

3 stops23h 33mMultiple Airlines

Sat 1/246:01 pmCLT - GUA

1 stop18h 19mMultiple Airlines

Deal found 12/23

$372

Thu 1/1512:15 pmGUA - CLT

1 stop21h 02mSpirit Airlines

Thu 1/226:01 pmCLT - GUA

1 stop18h 19mSpirit Airlines

Deal found 12/25

$376

Sat 1/171:28 pmGUA - CLT

1 stop10h 12mSpirit Airlines

Sat 1/247:43 pmCLT - GUA

2 stops16h 37mSpirit Airlines

Deal found 12/24

$334

Thu 1/2211:59 pmGUA - CHS

1 stop8h 51mUnited Airlines

Mon 1/265:13 pmCHS - GUA

1 stop23h 22mUnited Airlines

Deal found 12/23

$394

Thu 1/222:10 amGUA - CHS

1 stop18h 47mUnited Airlines

Mon 1/265:13 pmCHS - GUA

1 stop20h 13mUnited Airlines

Deal found 12/24

$396

Fri 1/232:10 amGUA - GSP

1 stop12h 25mUnited Airlines

Tue 1/276:49 amGSP - GUA

1 stop6h 37mUnited Airlines

Deal found 12/23

$591

Sat 1/241:28 pmGUA - SAV

1 stop26h 37mMultiple Airlines

Sat 1/3111:49 amSAV - GUA

2 stops24h 31mMultiple Airlines

Deal found 12/25

$355

Sat 1/244:40 pmGUA - SAV

2 stops18h 29mJetBlue

Sat 1/318:25 pmSAV - GUA

2 stops17h 36mJetBlue

Deal found 12/25

$486

Wed 1/285:10 amGUA - CLT

2 stops27h 45mMultiple Airlines

Fri 2/69:59 pmCLT - GUA

1 stop14h 21mMultiple Airlines

Deal found 12/24

$281

Wed 1/2812:15 pmGUA - CLT

2 stops11h 25mSpirit Airlines

Fri 2/67:43 pmCLT - GUA

2 stops16h 37mSpirit Airlines

Deal found 12/26

$315

Sat 1/314:40 pmGUA - SAV

1 stop25h 48mJetBlue

Tue 2/178:50 pmSAV - GUA

1 stop20h 52mJetBlue

Deal found 12/25

$492

One-way flights from Guatemala to South Carolina
Search for one-way flight options from Guatemala to South Carolina. Find affordable one-way fares based on user searches. Data last updated December 26, 2025.

Sat 1/1712:09 pmGUA - CLT

1 stop25h 06mFrontier

Deal found 12/24

$140

Mon 2/2312:15 pmGUA - CLT

1 stop24h 36mMultiple Airlines

Deal found 12/25

$154

Sun 2/221:29 pmGUA - CHS

1 stop27h 11mSpirit Airlines

Deal found 12/26

$155

Thu 1/87:12 pmGUA - CLT

1 stop13h 24mFrontier

Deal found 12/24

$157

Sat 2/211:29 pmGUA - CHS

1 stop27h 11mSpirit Airlines

Deal found 12/26

$158

Wed 1/71:39 pmGUA - CLT

1 stop8h 36mSpirit Airlines

Deal found 12/24

$175

Wed 2/112:11 pmGUA - CHS

1 stop17h 19mJetBlue

Deal found 12/25

$176

Mon 2/2312:15 pmGUA - CLT

2 stops10h 41mSpirit Airlines

Deal found 12/25

$179

Sat 1/1712:09 pmGUA - CLT

2 stops21h 08mMultiple Airlines

Deal found 12/24

$191

Wed 3/41:29 pmGUA - GSP

1 stop25h 22mMultiple Airlines

Deal found 12/24

$204

Mon 1/192:11 pmGUA - MYR

2 stops21h 01mMultiple Airlines

Deal found 12/23

$210

Sat 1/1712:09 pmGUA - MYR

2 stops23h 03mMultiple Airlines

Deal found 12/23

$211

Find flight deals from Guatemala to South Carolina

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$270 (Kiwi.com)
One-way from	$140 (Kiwi.com)
Popular in	November
Cheapest in	May
Average price	$438

Provider with most accurate pricing for Guatemala City La Aurora-Myrtle Beach Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Guatemala City La Aurora-Myrtle Beach Intl flights.

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From Guatemala to South Carolina

Search Deals

One-way flight from Guatemala to South Carolina

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($103 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($33 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Guatemala to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Guatemala CityCharlotte

GUA - CLT

GUACLT

Guatemala City La Aurora

Wed 1/28

5:10 am-9:55 am

2 stops27h 45m

Charlotte Douglas

Fri 2/6

9:59 pm-11:20 am

1 stop14h 21m

$281

Guatemala CityCharlotte

GUA - CLT

GUACLT

Guatemala City La Aurora

Tue 2/17

1:29 pm-8:26 am

1 stop17h 57m

Charlotte Douglas

Thu 2/26

6:01 pm-11:20 am

1 stop18h 19m

$284

Guatemala CityCharlotte

GUA - CLT

GUACLT

Guatemala City La Aurora

Thu 2/19

12:15 pm-10:17 am

1 stop21h 02m

Charlotte Douglas

Thu 2/26

7:05 pm-11:20 am

2 stops17h 15m

$291

Guatemala CityCharlotte

GUA - CLT

GUACLT

Guatemala City La Aurora

Wed 2/18

1:29 pm-11:56 pm

1 stop9h 27m

Charlotte Douglas

Mon 3/2

5:55 am-12:24 pm

1 stop7h 29m

$304

Guatemala CityCharlotte

GUA - CLT

GUACLT

Guatemala City La Aurora

Wed 1/28

12:15 pm-12:40 am

2 stops11h 25m

Charlotte Douglas

Fri 2/6

1:24 pm-11:20 am

2 stops22h 56m

$324

Guatemala CitySavannah

GUA - SAV

GUASAV

Guatemala City La Aurora

Sat 1/24

1:28 pm-5:05 pm

1 stop26h 37m

Savannah/Hilton Head

Sat 1/31

11:49 am-11:20 am

2 stops24h 31m

$355

Guatemala CityCharleston

GUA - CHS

GUACHS

Guatemala City La Aurora

Sat 3/7

12:05 am-9:04 am

1 stop7h 59m

Charleston

Tue 3/17

6:40 am-4:25 pm

1 stop11h 45m

$377

Guatemala CityCharleston

GUA - CHS

GUACHS

Guatemala City La Aurora

Mon 3/9

10:59 pm-9:15 am

1 stop8h 16m

Charleston

Tue 3/17

6:40 am-4:25 pm

1 stop11h 45m

$377

Guatemala CityCharleston

GUA - CHS

GUACHS

Guatemala City La Aurora

Mon 3/9

12:05 am-2:54 pm

1 stop12h 49m

Charleston

Tue 3/17

6:40 am-11:26 am

1 stop6h 46m

$377

Guatemala CityCharleston

GUA - CHS

GUACHS

Guatemala City La Aurora

Sat 3/7

12:05 am-9:04 am

1 stop7h 59m

Charleston

Wed 3/18

10:20 am-8:25 pm

1 stop12h 05m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Showing 1-10 of 57 results

...

Best time to book a flight from Guatemala to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guatemala with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guatemala to South Carolina

What is the cheapest month to book a flight from Guatemala to South Carolina?

Currently, November is the cheapest month in which you can book a flight from Guatemala to South Carolina (average of $195). Flying from Guatemala to South Carolina in August is currently the most expensive (average of $430). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GT to SC?

It’s typically best to fly out from Guatemala to South Carolina in the evening. Doing so could potentially save you 38% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Guatemala to South Carolina?

Travelers seeking maximum savings on their Guatemala to South Carolina flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Guatemala to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,013 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,064 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Spirit Airlines

6.3

Okay

8,206 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Guatemala to South Carolina?
Departing from Guatemala to South Carolina will take you 7h 59m. The distance between Guatemala and South Carolina is about 1425 mi. This flight may include one or multiple stops.
Can I find deals for flights from Guatemala to South Carolina that include hotel bookings?
Yes. In addition to deals on Guatemala to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Guatemala to South Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guatemala to South Carolina.
Can I find deals for business class flights from Guatemala to South Carolina?
Yes. Cheapflights offers flight deals from Guatemala to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Guatemala to South Carolina?
Currently, November is the cheapest month in which you can book a flight from Guatemala to South Carolina (average of $195). Flying from Guatemala to South Carolina in August is currently the most expensive (average of $430). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Guatemala to South Carolina

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Complete your trip

South Carolina car rentals

Charleston Airport car rentals

Myrtle Beach Intl Airport car rentals

Greenville Airport car rentals

Columbia Metropolitan Airport car rentals

Hilton Head Island Airport car rentals

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Myrtle Beach car rentals

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Florence car rentals

Top 3 airlines flying from Guatemala to South Carolina

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$270	Average$303	FlexibilityNo cancel fee	On-time65%
American Airlines	Cheapest$371	Average$550	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$547	Average$718	FlexibilityNo cancel fee	On-timeN/A

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$140+ Cheap flights from Guatemala to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Guatemala to South Carolina with Cheapflights

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Cheap flight deals from Guatemala to South Carolina

Cheapest flights from Guatemala to South CarolinaExplore the most affordable flight options available from Guatemala to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Explore the most affordable flight options available from Guatemala to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Find flight deals from Guatemala to South Carolina

Keep the following information in mind while searching for Guatemala to South Carolina flight deals. Data was last updated December 26, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Guatemala to South Carolina that are best for you.

Best time to book a flight from Guatemala to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guatemala with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Guatemala to South Carolina

What is the cheapest month to book a flight from Guatemala to South Carolina?

What is the cheapest time of day to fly from GT to SC?

Find hourly flight availability from Guatemala to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 26, 2025.

What is the cheapest day to fly from Guatemala to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Guatemala to South Carolina. Price data was last updated on December 16, 2024.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Guatemala to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Guatemala to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Guatemala to South Carolina?

Can I find deals for flights from Guatemala to South Carolina that include hotel bookings?

How can I find direct flights from Guatemala to South Carolina?

Can I find deals for business class flights from Guatemala to South Carolina?

What is the cheapest month to book a flight from Guatemala to South Carolina?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Guatemala to South Carolina

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Top 3 airlines flying from Guatemala to South Carolina

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Cheapest flights from Guatemala to South Carolina
Explore the most affordable flight options available from Guatemala to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.