South Carolina

$553+ Cheap flights from Frankfurt (FRA) to South Carolina

FRA — CHS
Dec 10 — Dec 171
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Cheap flight deals from Frankfurt to South Carolina

Cheapest flights from Frankfurt to South Carolina

Sun 11/2210:50 am -
1 stop12h 45m
Sat 12/57:00 am -
1 stop18h 15m
Deal found 11/8$821
Fri 12/2510:50 am -
1 stop29h 23m
Fri 1/17:00 am -
1 stop19h 50m
Deal found 11/8$822
Wed 11/2510:50 am -
1 stop15h 08m
Sun 11/294:12 pm -
1 stop10h 38m
Deal found 11/10$825
Thu 11/2610:50 am -
1 stop29h 45m
Wed 12/97:00 am -
1 stop18h 15m
Deal found 11/10$825
Wed 12/210:50 am -
1 stop18h 01m
Sun 12/67:00 am -
1 stop18h 15m
Deal found 11/6$829
Thu 11/2610:50 am -
1 stop29h 45m
Wed 12/911:40 am -
2 stops16h 45m
Deal found 11/10$832
Mon 11/2310:50 am -
2 stops35h 40m
Sun 11/298:54 am -
1 stop17h 56m
Deal found 11/9$840
Sun 11/2210:50 am -
1 stop17h 15m
Sat 11/2812:31 pm -
1 stop14h 19m
Deal found 11/8$842
Sun 11/2210:15 am -
1 stop18h 05m
Sat 12/57:44 pm -
1 stop31h 06m
Deal found 11/8$842
Thu 11/2610:50 am -
1 stop27h 39m
Wed 12/92:23 pm -
1 stop12h 27m
Deal found 11/10$846
Fri 11/2010:50 am -
1 stop15h 04m
Tue 11/2411:07 am -
1 stop15h 43m
Deal found 11/6$849
Mon 11/2310:50 am -
1 stop12h 45m
Sun 12/66:12 pm -
1 stop32h 38m
Deal found 11/9$849

Find flight deals from Frankfurt to South Carolina

Round-trip from

$807
(lastminute.com)

One-way from

$553
(Priceline)

Popular in

July

Cheapest in

November

Average price

$798
From Frankfurt am Main to South Carolina
One-way flight from Frankfurt am Main to South Carolina
Highest demand for flights based on searches. 5% potential increase in price ($52 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Frankfurt am Main Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Frankfurt am MainGreenville

FRA Frankfurt am Main - GSP Greenville

FRAGSP

Frankfurt am Main

Thu 1/28

10:15 am-10:10 pm

1 stop17h 55m

Greenville

Wed 12/31

12:00 am-6:00 am

Nonstop0h 00m

$553
Quickest round-trip

Frankfurt am MainMyrtle Beach

FRA Frankfurt am Main - MYR Myrtle Beach Intl

FRAMYR

Frankfurt am Main

Thu 12/31

10:50 am-5:37 pm

1 stop12h 47m

Myrtle Beach Intl

Wed 12/31

12:00 am-6:00 am

Nonstop0h 00m

$562

Frankfurt am MainGreenville

FRA Frankfurt am Main - GSP Greenville

FRAGSP

Frankfurt am Main

Thu 1/28

10:50 am-6:56 pm

1 stop14h 06m

Greenville

Wed 12/31

12:00 am-6:00 am

Nonstop0h 00m

$562

Frankfurt am MainGreenville

FRA Frankfurt am Main - GSP Greenville

FRAGSP

Frankfurt am Main

Tue 1/5

9:10 am-2:41 pm

3 stops59h 31m

Greenville

Wed 12/31

12:00 am-6:00 am

Nonstop0h 00m

$569

Frankfurt am MainGreenville

FRA Frankfurt am Main - GSP Greenville

FRAGSP

Frankfurt am Main

Tue 1/5

10:50 am-10:37 am

1 stop29h 47m

Greenville

Wed 12/31

12:00 am-6:00 am

Nonstop0h 00m

$650

Frankfurt am MainGreenville

FRA Frankfurt am Main - GSP Greenville

FRAGSP

Frankfurt am Main

Tue 1/5

10:50 am-1:14 pm

1 stop32h 24m

Greenville

Wed 12/31

12:00 am-6:00 am

Nonstop0h 00m

$650

Frankfurt am MainGreenville

FRA Frankfurt am Main - GSP Greenville

FRAGSP

Frankfurt am Main

Tue 1/5

10:50 am-11:27 am

1 stop30h 37m

Greenville

Wed 12/31

12:00 am-6:00 am

Nonstop0h 00m

$650

Frankfurt am MainMyrtle Beach

FRA Frankfurt am Main - MYR Myrtle Beach Intl

FRAMYR

Frankfurt am Main

Sun 1/3

10:50 am-11:49 pm

1 stop18h 59m

Myrtle Beach Intl

Wed 12/31

12:00 am-6:00 am

Nonstop0h 00m

$788

Frankfurt am MainMyrtle Beach

FRA Frankfurt am Main - MYR Myrtle Beach Intl

FRAMYR

Frankfurt am Main

Sun 11/15

6:30 am-10:05 am

3 stops57h 35m

Myrtle Beach Intl

Wed 12/31

12:00 am-6:00 am

Nonstop0h 00m

$796

Frankfurt am MainGreenville

FRA Frankfurt am Main - GSP Greenville

FRAGSP

Frankfurt am Main

Tue 12/22

9:10 am-2:38 pm

3 stops59h 28m

Greenville

Wed 12/31

12:00 am-6:00 am

Nonstop0h 00m

$819

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/7

Showing 1-10 of 49 resultsSorted by cheapest first
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Best time to book a flight from Frankfurt to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Frankfurt with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to South Carolina

What is the cheapest month to book a flight from Frankfurt am Main Airport to South Carolina?

Currently, January is the cheapest month in which you can book a flight from Frankfurt am Main Airport to South Carolina (average of $738). Flying from Frankfurt am Main Airport to South Carolina in September is currently the most expensive (average of $995). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Frankfurt am Main Airport to South Carolina?

Airfare is below average for this route at the moment.
Frankfurt am Main Airport to South Carolina flights typically cost between $870 and $871 in February.
The cheapest round-trip price found within the last 5 days was $807 on Scandinavian Airlines (Feb 2-Feb 10).

How far ahead should I book a flight from Frankfurt am Main Airport to South Carolina?

To ensure you get the cheapest price possible for a flight from Frankfurt am Main Airport to South Carolina, you should look to book at least 38 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with United Airlines and Lufthansa from Frankfurt am Main Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

6.7

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.3

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

Asha,Sep 2026

LGA - IAH

The flight was on time and boardi g was very organized and timely. Snacks are awful and having one little glass of juice was terrible. Fortunately, I had my water to keep me hydrated.

Food

6.7

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.3

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

Asha,Sep 2026

LGA - IAH

The flight was on time and boardi g was very organized and timely. Snacks are awful and having one little glass of juice was terrible. Fortunately, I had my water to keep me hydrated.

Food

6.7

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.3

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

Asha,Sep 2026

LGA - IAH

The flight was on time and boardi g was very organized and timely. Snacks are awful and having one little glass of juice was terrible. Fortunately, I had my water to keep me hydrated.

Related info for your journey

  • How long is the flight from Frankfurt am Main Airport to South Carolina?

    Airlines like British Airways, American Airlines, and Delta fly from Frankfurt am Main Airport to South Carolina in about 15h 23m. The time it takes to get you to your destination can typically vary by up to 3h 53m. There are 4450 mi between Frankfurt am Main Airport and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Frankfurt am Main Airport to South Carolina?

  • Can I find deals for flights from Frankfurt to South Carolina that include hotel bookings?

    Yes. In addition to deals on Frankfurt to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to South Carolina.

  • Can I find deals for business class flights from Frankfurt to South Carolina?

    Yes. Cheapflights offers flight deals from Frankfurt to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Frankfurt am Main Airport to South Carolina (average of $738). Flying from Frankfurt am Main Airport to South Carolina in September is currently the most expensive (average of $995). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Frankfurt to South Carolina

AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$730Average$1,062FlexibilityNo cancel feeOn-time76%
United AirlinesCheapest$815Average$1,027FlexibilityNo cancel feeOn-time69%

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