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South Carolina

$101+ Cheap flights from Biloxi, MS to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — CHS
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
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Cheap flight deals from Biloxi to South Carolina

Cheapest flights from Biloxi to South Carolina
Explore the most affordable flight options available from Biloxi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:50 pm
GPT
-
GSP
1 stop10h 40m
Multiple Airlines
Sun 8/23:40 pm
GSP
-
GPT
1 stop17h 01m
Multiple Airlines
Deal found 3/14$269
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:50 pm
GPT
-
CLT
1 stop27h 09m
Multiple Airlines
Wed 7/15:10 pm
CLT
-
GPT
1 stop27h 00m
Multiple Airlines
Deal found 3/14$277
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:43 pm
GPT
-
SAV
1 stop6h 09m
American Airlines
Sun 8/168:36 pm
SAV
-
GPT
1 stop4h 27m
American Airlines
Deal found 3/13$309
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/275:57 pm
GPT
-
SAV
1 stop3h 14m
Delta
Tue 3/314:57 pm
SAV
-
GPT
1 stop6h 18m
Delta
Deal found 3/12$323
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/297:20 pm
GPT
-
CHS
1 stop12h 23m
Breeze Airways
Thu 4/23:01 pm
CHS
-
GPT
1 stop4h 39m
Breeze Airways
Deal found 3/14$331
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:55 pm
GPT
-
SAV
1 stop6h 05m
Delta
Mon 6/86:50 pm
SAV
-
GPT
1 stop4h 17m
Delta
Deal found 3/14$331
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:54 pm
GPT
-
CHS
1 stop13h 41m
Breeze Airways
Fri 4/39:29 pm
CHS
-
GPT
2 stops46h 11m
Breeze Airways
Deal found 3/15$333
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:00 pm
GPT
-
SAV
1 stop6h 53m
United Airlines
Sat 8/297:00 am
SAV
-
GPT
1 stop7h 26m
United Airlines
Deal found 3/12$349
This Breeze Airways deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:46 pm
GPT
-
GSP
1 stop19h 43m
Breeze Airways
Thu 10/810:07 am
GSP
-
GPT
1 stop23h 44m
Breeze Airways
Deal found 3/13$353
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:15 pm
GPT
-
SAV
1 stop3h 32m
Delta
Sun 7/195:30 am
SAV
-
GPT
1 stop5h 07m
Delta
Deal found 3/13$359
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/297:20 pm
GPT
-
CLT
1 stop11h 43m
Multiple Airlines
Thu 4/21:46 pm
CLT
-
GPT
1 stop5h 54m
Multiple Airlines
Deal found 3/14$365
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:20 pm
GPT
-
CLT
1 stop13h 17m
Multiple Airlines
Sun 4/121:46 pm
CLT
-
GPT
1 stop5h 54m
Multiple Airlines
Deal found 3/16$379

Find flight deals from Biloxi to South Carolina

Keep the following information in mind while searching for Biloxi to South Carolina flight deals. Data was last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$207
(Breeze Airways)

One-way from

$101
(Kiwi.com)
Provider with most accurate pricing for Gulfport Biloxi Regional-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Myrtle Beach Intl flights.
Search Deals
From Biloxi to South Carolina
Search Deals
One-way flight from Biloxi to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Biloxi to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportGreenville

GPT - GSP

GPTGSP

Gulfport Biloxi Regional

Thu 7/30

7:50 pm-7:30 am

1 stop10h 40m

Greenville

Sun 8/2

3:40 pm-7:41 am

1 stop17h 01m

$269

GulfportSavannah

GPT - SAV

GPTSAV

Gulfport Biloxi Regional

Fri 3/27

5:57 pm-10:11 pm

1 stop3h 14m

Savannah/Hilton Head

Tue 3/31

4:57 pm-10:15 pm

1 stop6h 18m

$323

GulfportSavannah

GPT - SAV

GPTSAV

Gulfport Biloxi Regional

Thu 6/4

1:55 pm-9:00 pm

1 stop6h 05m

Savannah/Hilton Head

Mon 6/8

6:50 pm-10:07 pm

1 stop4h 17m

$331

GulfportCharleston

GPT - CHS

GPTCHS

Gulfport Biloxi Regional

Mon 3/30

6:54 pm-9:35 am

1 stop13h 41m

Charleston

Fri 4/3

9:29 pm-6:40 pm

2 stops46h 11m

$333

GulfportSavannah

GPT - SAV

GPTSAV

Gulfport Biloxi Regional

Thu 7/16

2:15 pm-6:47 pm

1 stop3h 32m

Savannah/Hilton Head

Sun 7/19

7:00 am-9:37 am

1 stop3h 37m

$359

GulfportCharleston

GPT - CHS

GPTCHS

Gulfport Biloxi Regional

Fri 5/29

2:00 pm-10:15 pm

1 stop7h 15m

Charleston

Sat 5/30

6:50 am-1:25 pm

1 stop7h 35m

$391

GulfportMyrtle Beach

GPT - MYR

GPTMYR

Gulfport Biloxi Regional

Fri 3/27

5:57 pm-12:04 am

1 stop5h 07m

Myrtle Beach Intl

Tue 3/31

6:00 am-8:50 am

1 stop3h 50m

$399

GulfportCharlotte

GPT - CLT

GPTCLT

Gulfport Biloxi Regional

Thu 4/9

7:20 pm-9:37 am

1 stop13h 17m

Charlotte Douglas

Sun 4/12

1:20 pm-9:00 am

2 stops20h 40m

$401

GulfportCharleston

GPT - CHS

GPTCHS

Gulfport Biloxi Regional

Sat 6/6

6:38 pm-11:59 pm

1 stop4h 21m

Charleston

Tue 6/9

6:40 am-12:13 pm

1 stop6h 33m

$402

GulfportGreenville

GPT - GSP

GPTGSP

Gulfport Biloxi Regional

Mon 8/10

6:30 pm-11:57 pm

1 stop4h 27m

Greenville

Mon 9/21

8:40 pm-12:07 am

1 stop4h 27m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 59 resultsSorted by cheapest first
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Best time to book a flight from Biloxi to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to South Carolina

What is the cheapest month to book a flight from Biloxi to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Biloxi to South Carolina (average of $102). Flying from Biloxi to South Carolina in April is currently the most expensive (average of $155). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to SC?

Find hourly flight availability from Biloxi to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 17, 2026.

Unlike at noon, when flights are generally more expensive, you can save up to 68% on flights from Biloxi to South Carolina by exploring options for tickets in the evening.

What is the cheapest day to fly from Biloxi to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Biloxi to South Carolina. Price data was last updated on March 14, 2026.

Travelers seeking maximum savings on their Biloxi to South Carolina flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 17, 2026.
See what other customers who have flown with Delta and American Airlines from Biloxi to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,288 reviews

Entertainment

7.8

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,288 reviews
Delta
7.9
Good
8,288 reviews

Entertainment

7.8

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,468 reviews
Delta
7.9
Good
8,288 reviews

Entertainment

7.8

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Biloxi to South Carolina flight route?

    This flight path from Biloxi to South Carolina was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Biloxi to South Carolina?

    For as low as $323, Delta can have you in South Carolina from Biloxi in 3h 14m. There are 479 mi between Biloxi and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Biloxi to South Carolina?

    The most popular route from Biloxi to South Carolina is Gulfport Biloxi Regional - Charlotte Douglas. You may also consider Gulfport Biloxi Regional - Charleston or Gulfport Biloxi Regional - Greenville.

  • What are the cheapest flights from Biloxi to South Carolina?

    On average you can expect to pay $254 for a flight from Biloxi to South Carolina. The cheapest flight overall is $99 while the most popular route, (Gulfport Biloxi Regional - Charlotte Douglas) is currently priced at $277.

  • Can I find deals for flights from Biloxi to South Carolina that include hotel bookings?

    Yes. In addition to deals on Biloxi to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to South Carolina.

  • Can I find deals for business class flights from Biloxi to South Carolina?

    Yes. Cheapflights offers flight deals from Biloxi to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Biloxi to South Carolina (average of $102). Flying from Biloxi to South Carolina in April is currently the most expensive (average of $155). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Biloxi to South Carolina

Discover the top 5 airlines that operate flights from Biloxi to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$118Average$187FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$140Average$399FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$142Average$170FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$206Average$391FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$276Average$366FlexibilityNo cancel feeOn-time63%

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