HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Africa

$659+ Cheap flights from Missouri to South Africa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — JNB
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to South Africa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to South Africa

Keep the following information in mind while searching for Missouri to South Africa flight deals. Data was last updated June 12, 2025.

Round-trip from

$1,185
(Ovago)

One-way from

$659
(Mytrip)

Popular in

July

Cheapest in

January

Average price

$1,738
From Missouri to South Africa
Search Deals
One-way flight from Missouri to South Africa
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($280 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($50 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Missouri to South Africa

Cheapest flights from Missouri to South Africa
Explore the most affordable flight options available from Missouri to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Ovago deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/87:59 pmSTL - CPT
2 stops32h 01mBritish Airways
Sun 9/146:55 pmCPT - STL
2 stops30h 32mBritish Airways
Deal found 6/12$1,185
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/83:44 pmMCI - CPT
2 stops36h 16mAmerican Airlines
Sun 9/146:55 pmCPT - MCI
2 stops27h 14mAmerican Airlines
Deal found 6/12$1,205
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/83:57 pmSTL - CPT
2 stops36h 03mAmerican Airlines
Sun 9/146:55 pmCPT - STL
2 stops31h 18mAmerican Airlines
Deal found 6/11$1,205
This Etihad Airways deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Etihad Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/35:55 amSTL - JNB
2 stops43h 25mMultiple Airlines
Mon 9/159:50 amJNB - STL
2 stops42h 29mMultiple Airlines
Deal found 6/10$1,243
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/42:29 pmMCI - JNB
2 stops33h 01mAmerican Airlines
Tue 11/1110:05 pmJNB - MCI
2 stops27h 42mAmerican Airlines
Deal found 6/10$1,296
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/83:57 pmSTL - JNB
2 stops32h 03mAmerican Airlines
Sun 9/149:15 pmJNB - STL
2 stops28h 12mAmerican Airlines
Deal found 6/11$1,296
This oojo deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:34 amSTL - JNB
2 stops45h 01mQatar Airways
Tue 10/218:25 pmJNB - STL
2 stops33h 44mQatar Airways
Deal found 6/9$1,358
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/69:17 amSTL - CPT
2 stops23h 03mUnited Airlines
Tue 9/238:00 pmCPT - STL
1 stop21h 02mUnited Airlines
Deal found 6/11$1,375
This oojo deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/208:00 pmMCI - CPT
2 stops31h 50mQatar Airways
Mon 11/312:35 pmCPT - MCI
2 stops33h 18mQatar Airways
Deal found 6/12$1,383
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:30 amSTL - JNB
2 stops28h 15mUnited Airlines
Wed 11/123:05 pmJNB - STL
2 stops27h 47mUnited Airlines
Deal found 6/11$1,385
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:40 pmSTL - JNB
1 stop19h 00mDelta
Tue 10/216:50 pmJNB - STL
2 stops30h 12mDelta
Deal found 6/9$1,411
This Gurufare deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:28 pmSTL - JNB
2 stops32h 07mLufthansa
Tue 10/77:00 pmJNB - STL
1 stop25h 30mLufthansa
Deal found 6/12$1,414

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Missouri to South Africa that are best for you.

Fly from

Missouri

Fly to

South Africa

Route

Depart

Return

Price

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Mon 9/8

7:59 pm-11:00 am

2 stops32h 01m

Cape Town Intl

Sun 9/14

6:55 pm-6:25 pm

2 stops30h 30m

$1,185

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Mon 9/8

3:44 pm-11:00 am

2 stops36h 16m

Cape Town Intl

Sun 9/14

6:55 pm-3:09 pm

2 stops27h 14m

$1,205

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Mon 9/8

3:57 pm-11:00 am

2 stops36h 03m

Cape Town Intl

Sun 9/14

6:55 pm-7:13 pm

2 stops31h 18m

$1,205

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Wed 9/3

5:55 am-8:20 am

2 stops43h 25m

Johannesburg OR Tambo

Mon 9/15

9:50 am-9:19 pm

2 stops42h 29m

$1,243

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Mon 9/8

3:57 pm-7:00 am

2 stops32h 03m

Johannesburg OR Tambo

Sun 9/14

9:15 pm-6:27 pm

2 stops28h 12m

$1,296

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sat 9/6

9:17 am-3:20 pm

2 stops23h 03m

Cape Town Intl

Mon 9/22

7:50 pm-3:44 pm

2 stops26h 54m

$1,375

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Wed 9/3

3:30 pm-8:35 am

1 stop34h 05m

Johannesburg OR Tambo

Mon 9/15

7:00 pm-3:44 pm

2 stops27h 44m

$1,417

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Mon 9/8

12:45 pm-3:20 pm

1 stop19h 35m

Cape Town Intl

Sun 9/14

8:00 pm-8:42 pm

2 stops31h 42m

$1,460

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sat 9/6

7:00 am-5:50 pm

1 stop27h 50m

Cape Town Intl

Sun 9/14

8:05 pm-12:25 pm

1 stop23h 20m

$1,470

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Wed 9/3

5:11 pm-7:40 pm

1 stop19h 29m

Johannesburg OR Tambo

Mon 9/15

9:55 pm-6:02 pm

1 stop27h 07m

$1,470

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 38 results
1
2
3
4

Best time to book a flight from Missouri to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to South Africa

What is the cheapest month to book a flight from Missouri to South Africa?

Currently, January is the cheapest month in which you can book a flight from Missouri to South Africa (average of $1,173). Flying from Missouri to South Africa in July is currently the most expensive (average of $1,696). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ZA?

Find hourly flight availability from Missouri to South Africa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Missouri to South Africa, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Africa by month

Plan your trip to South Africa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Africa ranges from 0.0 - 4.7 inches per month. January is typically the wettest month, when rainfall can reach 4.7 in. June is typically the driest time to visit South Africa when rainfall is around 0.0 in.

Temperature in South Africa by month

Plan your trip to South Africa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Africa, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 68.0 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 50.0 F).

Reviews of airlines servicing South Africa

Get insights into the airlines that provide service to South Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Africa. Reviews last updated June 12, 2025.
Read through reviews of airlines operating flights from Missouri to South Africa, such as Emirates, Delta and KLM. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Emirates
8.1
Very good
3,264 reviews

Overall

8.1

Entertainment

8.2

Comfort

8.0

Food

7.8

Boarding

8.1

Crew

8.3

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.
Emirates
8.1
Very good
3,264 reviews
Emirates
8.1
Very good
3,264 reviews

Overall

8.1

Entertainment

8.2

Comfort

8.0

Food

7.8

Boarding

8.1

Crew

8.3

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.
Delta
8.0
Very good
7,946 reviews
Emirates
8.1
Very good
3,264 reviews

Overall

8.1

Entertainment

8.2

Comfort

8.0

Food

7.8

Boarding

8.1

Crew

8.3

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.
KLM
7.8
Good
1,358 reviews
Emirates
8.1
Very good
3,264 reviews

Overall

8.1

Entertainment

8.2

Comfort

8.0

Food

7.8

Boarding

8.1

Crew

8.3

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.
SWISS
7.5
Good
1,623 reviews
Emirates
8.1
Very good
3,264 reviews

Overall

8.1

Entertainment

8.2

Comfort

8.0

Food

7.8

Boarding

8.1

Crew

8.3

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.
Qatar Airways
7.4
Good
3,584 reviews
Emirates
8.1
Very good
3,264 reviews

Overall

8.1

Entertainment

8.2

Comfort

8.0

Food

7.8

Boarding

8.1

Crew

8.3

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.

Related info for your journey

Find useful and relevant information for your journey from Missouri to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to South Africa one-way?

    To fly one-way, consider booking your trip with Qatar Airways, which is currently one of the cheapest options available, starting at $700. Lufthansa flights start at $837 while deals on United Airlines start at $1,143 one-way.

  • Can I find deals for flights from Missouri to South Africa that include hotel bookings?

    Yes. In addition to deals on Missouri to South Africa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to South Africa.

  • Can I find deals for business class flights from Missouri to South Africa?

    Yes. Cheapflights offers flight deals from Missouri to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to South Africa?

    Currently, January is the cheapest month in which you can book a flight from Missouri to South Africa (average of $1,173). Flying from Missouri to South Africa in July is currently the most expensive (average of $1,696). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Cairo flights
John F Kennedy Intl to Casablanca flights
John F Kennedy Intl to Accra flights
John F Kennedy Intl to Lagos flights
Newark to Cairo flights
Dulles Intl to Cairo flights
John F Kennedy Intl to Jomo Kenyatta Intl flights
Dulles Intl to Lagos flights
LaGuardia to Cairo flights
Los Angeles to Cairo flights
Dulles Intl to Casablanca flights
Dulles Intl to Accra flights
Newark to Accra flights
San Francisco to Cairo flights
Newark to OR Tambo flights
Hobby to Lagos flights
Newark to Lagos flights
Boston to Casablanca flights
Hobby to Cairo flights
Atlanta to Lagos flights
O'Hare Intl to Cairo flights
Reagan-National to Cairo flights
Newark to Casablanca flights
John F Kennedy Intl to Marrakech flights
Newark to Marrakech flights
Newark to Jomo Kenyatta Intl flights
George Bush Intcntl to Lagos flights
John F Kennedy Intl to OR Tambo flights
Baltimore to Cairo flights
LaGuardia to Accra flights
Seattle to Cairo flights
LaGuardia to Casablanca flights
Boston to Cairo flights
LaGuardia to Jomo Kenyatta Intl flights
Newark to Cape Town flights
Reagan-National to Lagos flights
Baltimore to Lagos flights
George Bush Intcntl to Cairo flights
John F Kennedy Intl to Cape Town flights
Dulles Intl to Jomo Kenyatta Intl flights
Dallas/Fort Worth to Lagos flights
Atlanta to Accra flights
Dallas/Fort Worth to Cairo flights
Reagan-National to Accra flights
Baltimore to Accra flights
Atlanta to OR Tambo flights
Reagan-National to Casablanca flights
O'Hare Intl to Lagos flights
Minneapolis to Jomo Kenyatta Intl flights
LaGuardia to Lagos flights

Top 3 airlines flying from Missouri to South Africa

Discover the top 3 airlines that operate flights from Missouri to South Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$924Average$1,244FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$1,061Average$1,628FlexibilityNo cancel feeOn-time69%
DeltaCheapest$1,080Average$1,881FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.