$90+ Cheap flights from Mesa, AZ to Sioux Falls (FSD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — FSD
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to Sioux Falls with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mesa to Sioux Falls
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Cheapest flights from Mesa to Sioux FallsExplore the most affordable flight options available from Mesa to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Mesa to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:21 pm -
1 stop14h 35m
Mon 11/21:41 pm -
1 stop24h 49m
Deal found 9/4![Multiple Airlines logo]()
$240
This Travelocity deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:15 am -
1 stop8h 52m
Mon 9/288:52 pm -
1 stop24h 59m
Deal found 9/7![Frontier logo]()
$259
This Frontier deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:25 am -
1 stop11h 42m
Fri 9/258:52 pm -
1 stop4h 51m
Deal found 9/6![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:56 pm -
2 stops36h 20m
Mon 10/512:41 pm -
1 stop12h 06m
Deal found 9/8![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:24 pm -
1 stop14h 02m
Sun 10/1112:41 pm -
1 stop12h 37m
Deal found 9/8![Multiple Airlines logo]()
$269
This Frontier deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:25 am -
1 stop11h 42m
Mon 9/218:52 pm -
1 stop4h 51m
Deal found 9/5![Frontier logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:56 pm -
2 stops36h 20m
Mon 10/261:41 pm -
1 stop11h 37m
Deal found 9/4![Multiple Airlines logo]()
$306
This Expedia deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:29 am -
1 stop6h 38m
Mon 9/148:52 pm -
1 stop19h 25m
Deal found 9/6![Frontier logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:56 pm -
1 stop19h 20m
Mon 11/21:41 pm -
1 stop24h 49m
Deal found 9/8![Multiple Airlines logo]()
$316
Best flights from Mesa to Sioux FallsDiscover carefully curated flight deals from Mesa to Sioux Falls that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Mesa to Sioux Falls that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:15 pm -
1 stop7h 56m
Wed 10/216:50 pm -
1 stop5h 09m
Deal found 9/4![United Airlines logo]()
$440
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:03 pm -
1 stop5h 29m
Sat 10/175:00 pm -
1 stop8h 26m
Deal found 9/5![Delta logo]()
$582
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:15 pm -
1 stop7h 56m
Mon 10/265:06 pm -
1 stop5h 31m
Deal found 9/4![United Airlines logo]()
$496
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:53 pm -
1 stop6h 44m
Sun 11/295:55 am -
1 stop4h 48m
Deal found 9/7![United Airlines logo]()
$516
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/192:48 pm -
1 stop4h 27m
Wed 12/309:00 am -
1 stop7h 27m
Deal found 9/8![United Airlines logo]()
$555
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:55 am -
2 stops9h 42m
Tue 11/37:48 am -
2 stops8h 40m
Deal found 9/6![United Airlines logo]()
$565
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/91:15 pm -
1 stop7h 56m
Sun 10/189:42 am -
1 stop4h 45m
Deal found 9/5![United Airlines logo]()
$572
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:50 am -
2 stops9h 17m
Wed 9/236:50 pm -
1 stop5h 19m
Deal found 9/4![United Airlines logo]()
$576
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:53 pm -
1 stop6h 44m
Sun 11/81:20 pm -
1 stop6h 02m
Deal found 9/4![United Airlines logo]()
$586
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:00 pm -
2 stops9h 29m
Fri 10/3011:22 am -
1 stop23h 21m
Deal found 9/8![United Airlines logo]()
$590
Last-minute flights from Mesa to Sioux FallsDiscover last-minute flight deals from Mesa to Sioux Falls. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Sioux Falls. Data last updated September 9, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:29 am -
1 stop6h 38m
Mon 9/148:52 pm -
1 stop19h 25m
Deal found 9/6![Frontier logo]()
$310
This Frontier deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:25 am -
1 stop11h 42m
Mon 9/218:52 pm -
1 stop4h 51m
Deal found 9/5![Frontier logo]()
$280
This Frontier deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:25 am -
1 stop11h 42m
Fri 9/258:52 pm -
1 stop4h 51m
Deal found 9/6![Frontier logo]()
$260
This Travelocity deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:15 am -
1 stop8h 52m
Mon 9/288:52 pm -
1 stop24h 59m
Deal found 9/7![Frontier logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:56 pm -
2 stops36h 20m
Mon 10/512:41 pm -
1 stop12h 06m
Deal found 9/8![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:24 pm -
1 stop14h 02m
Sun 10/1112:41 pm -
1 stop12h 37m
Deal found 9/8![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:56 pm -
2 stops36h 20m
Mon 10/261:41 pm -
1 stop11h 37m
Deal found 9/4![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:21 pm -
1 stop14h 35m
Mon 11/21:41 pm -
1 stop24h 49m
Deal found 9/4![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:56 pm -
1 stop19h 20m
Mon 11/21:41 pm -
1 stop24h 49m
Deal found 9/8![Multiple Airlines logo]()
$316
One-way flights from Mesa to Sioux FallsSearch for one-way flight options from Mesa to Sioux Falls. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Mesa to Sioux Falls. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Trip.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:27 am -
1 stop24h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:24 pm -
1 stop14h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:39 pm -
1 stop12h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:30 am -
1 stop24h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:21 pm -
1 stop14h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:33 pm -
2 stops28h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:22 pm -
1 stop16h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$132
This Super.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:25 am -
1 stop11h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$133
This Super.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:56 pm -
1 stop21h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$134
Find flight deals from Mesa to Sioux Falls
Keep the following information in mind while searching for Mesa to Sioux Falls flight deals. Data was last updated September 9, 2026.
Round-trip from | $240 (Kiwi.com) |
|---|---|
One-way from | $90 (Trip.com) |
Popular in | June |
Cheapest in | December |
Average price | $480 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Mesa to Sioux Falls that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixSioux Falls
PHX Phoenix Sky Harbor Intl - FSD Sioux Falls Joe Foss Field
PHXFSD
Phoenix Sky Harbor Intl
Thu 10/15
1:12 pm-11:00 am
2 stops19h 48m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$165
PhoenixSioux Falls
PHX Phoenix Sky Harbor Intl - FSD Sioux Falls Joe Foss Field
PHXFSD
Phoenix Sky Harbor Intl
Wed 9/30
8:39 pm-11:16 am
1 stop12h 37m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$171
PhoenixSioux Falls
PHX Phoenix Sky Harbor Intl - FSD Sioux Falls Joe Foss Field
PHXFSD
Phoenix Sky Harbor Intl
Tue 10/6
7:05 am-11:22 pm
1 stop14h 17m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$347
Quickest round-trip
PhoenixSioux Falls
PHX Phoenix Sky Harbor Intl - FSD Sioux Falls Joe Foss Field
PHXFSD
Phoenix Sky Harbor Intl
Tue 10/6
1:15 pm-11:11 pm
1 stop7h 56m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$351
PhoenixSioux Falls
PHX Phoenix Sky Harbor Intl - FSD Sioux Falls Joe Foss Field
PHXFSD
Phoenix Sky Harbor Intl
Fri 9/18
8:57 am-11:44 pm
2 stops12h 47m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$352
PhoenixSioux Falls
PHX Phoenix Sky Harbor Intl - FSD Sioux Falls Joe Foss Field
PHXFSD
Phoenix Sky Harbor Intl
Tue 3/2
12:55 am-10:51 pm
1 stop20h 56m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$356
PhoenixSioux Falls
PHX Phoenix Sky Harbor Intl - FSD Sioux Falls Joe Foss Field
PHXFSD
Phoenix Sky Harbor Intl
Thu 10/8
12:50 am-11:22 pm
1 stop20h 32m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$356
PhoenixSioux Falls
PHX Phoenix Sky Harbor Intl - FSD Sioux Falls Joe Foss Field
PHXFSD
Phoenix Sky Harbor Intl
Fri 3/5
6:00 pm-3:50 pm
1 stop20h 50m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$362
PhoenixSioux Falls
PHX Phoenix Sky Harbor Intl - FSD Sioux Falls Joe Foss Field
PHXFSD
Phoenix Sky Harbor Intl
Sun 3/7
12:55 am-10:51 pm
1 stop20h 56m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$362
PhoenixSioux Falls
PHX Phoenix Sky Harbor Intl - FSD Sioux Falls Joe Foss Field
PHXFSD
Phoenix Sky Harbor Intl
Sat 3/6
12:55 am-10:51 pm
1 stop20h 56m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$362
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Mesa to Sioux Falls
Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Mesa with our price prediction graph.
PHX-FSD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Sioux Falls
MS9-FSD
PHX-FSD
What is the cheapest time of day to fly from MS9 to FSD?
Find hourly flight availability from Mesa to Sioux Falls. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 9, 2026.
It’s typically best to fly out from Mesa to Sioux Falls at noon. Doing so could potentially save you 58% on the flight price compared to flying in the evening, which is usually more expensive.
How much does it cost to fly round-trip from Mesa to Sioux Falls?
Airfare is below average for this route at the moment.
Mesa to Sioux Falls flights typically cost between $423 and $570 in October.The cheapest round-trip price found within the last 5 days was $240 on Multiple Airlines (Oct 28-Nov 2).
Reviews of airlines servicing Sioux Falls
Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated September 9, 2026.
Peruse reviews from past customers who have flown with United Airlines,Allegiant Air, andAmerican Airlines from Mesa to Sioux Falls to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Overall
7.4
Entertainment
7.1
Boarding
7.7
Food
6.7
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Comfort
7.3
Overall
7.4
Entertainment
7.1
Boarding
7.7
Food
6.7
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Comfort
7.3
Overall
7.4
Entertainment
7.1
Boarding
7.7
Food
6.7
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Comfort
7.3
Overall
7.4
Entertainment
7.1
Boarding
7.7
Food
6.7
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Comfort
7.3
Overall
7.4
Entertainment
7.1
Boarding
7.7
Food
6.7
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Mesa to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Sioux Falls?
Book flights to Sioux Falls if you plan to visit one of these locationsYankton
Marshall
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Mesa and Sioux Falls flights
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Consider these flights traveling from Mesa to Sioux Falls.
Top 4 airlines flying from Mesa to Sioux Falls
Discover the top 4 airlines that operate flights from Mesa to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$118 | Average$200 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$170 | Average$249 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$260 | Average$479 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$343 | Average$570 | FlexibilityNo cancel fee | On-time69% |