Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Fort Smith as you normally would.
For a flight from Mesa to Fort Smith, you will be flying into Fort Smith. Fort Smith (FSM) is just 3.8 mi from the center of the city. Fort Smith is the only Fort Smith airport and it handles 0 inbound flights from Mesa per day. 2 airlines have flights to Fort Smith from Mesa on a regular basis.