Sao Paulo

$315+ Cheap flights from South Carolina to Sao Paulo, Brazil (SAO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SAO
Mar 5 — Mar 121
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Sao Paulo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Sao Paulo

Cheapest flights from South Carolina to Sao Paulo
Explore the most affordable flight options available from South Carolina to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:00 am
CLT
-
GRU
2 stops18h 40m
Multiple Airlines
Thu 3/265:50 am
GRU
-
CLT
2 stops31h 17m
Multiple Airlines
Deal found 2/2$545
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:00 am
CLT
-
VCP
1 stop12h 25m
Multiple Airlines
Wed 3/2510:45 pm
VCP
-
CLT
1 stop22h 32m
Multiple Airlines
Deal found 1/31$584
This Avianca Connect deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:12 am
CLT
-
GRU
2 stops16h 28m
Multiple Airlines
Tue 3/105:25 pm
GRU
-
CLT
2 stops19h 55m
Multiple Airlines
Deal found 2/1$607
This SmartFares deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:34 pm
CLT
-
GRU
2 stops21h 36m
GOL
Wed 9/309:55 pm
GRU
-
CLT
2 stops26h 36m
GOL
Deal found 2/2$610
This SmartFares deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:34 pm
CLT
-
CGH
2 stops20h 46m
GOL
Wed 9/306:30 am
CGH
-
CLT
2 stops18h 01m
GOL
Deal found 2/2$615
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:12 am
CLT
-
GRU
2 stops34h 18m
Multiple Airlines
Fri 4/241:20 am
GRU
-
CLT
2 stops23h 29m
Multiple Airlines
Deal found 2/2$626
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:00 am
CLT
-
CGH
3 stops26h 00m
Multiple Airlines
Thu 3/266:30 am
CGH
-
CLT
3 stops19h 08m
Multiple Airlines
Deal found 2/2$626
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:55 am
CLT
-
GRU
1 stop32h 00m
Multiple Airlines
Wed 4/84:05 am
GRU
-
CLT
2 stops21h 20m
Multiple Airlines
Deal found 2/2$632
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:12 am
CLT
-
GRU
2 stops28h 03m
Multiple Airlines
Wed 3/256:00 pm
GRU
-
CLT
3 stops22h 00m
Multiple Airlines
Deal found 1/31$640
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:00 am
CLT
-
VCP
3 stops25h 10m
Multiple Airlines
Thu 3/266:20 am
VCP
-
CLT
2 stops28h 51m
Multiple Airlines
Deal found 2/2$642
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2311:12 am
CLT
-
GRU
3 stops34h 18m
Multiple Airlines
Wed 5/271:00 am
GRU
-
CLT
2 stops20h 29m
Multiple Airlines
Deal found 2/2$647
This GOL deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:55 pm
CLT
-
GRU
2 stops38h 00m
GOL
Wed 9/99:55 pm
GRU
-
CLT
2 stops37h 40m
GOL
Deal found 2/2$649

Find flight deals from South Carolina to Sao Paulo

Keep the following information in mind while searching for South Carolina to Sao Paulo flight deals. Data was last updated February 3, 2026.

Most accurate provider

AranGrant
2 stars

Most trusted provider

AranGrant
2 stars

Round-trip from

$545
(Mytrip)

One-way from

$315
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Sao Paulo (SAO) flights.
From South Carolina to Sao Paulo (SAO)
One-way flight from South Carolina to Sao Paulo (SAO)

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from South Carolina to Sao Paulo that are best for you.

Fly from

South Carolina

Fly to

Sao Paulo

Route

Depart

Return

Price

CharlotteSao Paulo

CLT - GRU

CLTGRU

Charlotte Douglas

Thu 3/19

7:00 am-2:40 am

2 stops18h 40m

Sao Paulo Guarulhos Intl

Thu 3/26

5:50 am-12:07 pm

2 stops31h 17m

$545

CharlotteSao Paulo

CLT - VCP

CLTVCP

Charlotte Douglas

Wed 3/18

6:00 am-7:25 pm

1 stop12h 25m

Sao Paulo Viracopos

Wed 3/25

10:45 pm-8:17 pm

1 stop22h 32m

$584

CharlotteSao Paulo

CLT - CGH

CLTCGH

Charlotte Douglas

Thu 3/19

7:00 am-10:00 am

3 stops26h 00m

Sao Paulo Congonhas

Thu 3/26

6:30 am-12:38 am

3 stops19h 08m

$626

CharlotteSao Paulo

CLT - GRU

CLTGRU

Charlotte Douglas

Wed 3/18

11:12 am-4:15 pm

2 stops28h 03m

Sao Paulo Guarulhos Intl

Wed 3/25

6:00 pm-3:00 pm

3 stops22h 00m

$640

CharlotteSao Paulo

CLT - GRU

CLTGRU

Charlotte Douglas

Wed 4/1

6:00 am-5:25 am

2 stops22h 25m

Sao Paulo Guarulhos Intl

Tue 4/7

1:20 am-8:17 pm

2 stops19h 57m

$641

CharlotteSao Paulo

CLT - VCP

CLTVCP

Charlotte Douglas

Thu 3/19

7:00 am-9:10 am

3 stops25h 10m

Sao Paulo Viracopos

Thu 3/26

6:20 am-10:11 am

2 stops28h 51m

$642

CharlotteSao Paulo

CLT - GRU

CLTGRU

Charlotte Douglas

Sat 2/28

5:49 pm-1:35 am

3 stops29h 46m

Sao Paulo Guarulhos Intl

Thu 3/5

2:40 am-4:54 pm

2 stops16h 14m

$654

CharlotteSao Paulo

CLT - GRU

CLTGRU

Charlotte Douglas

Sat 2/28

5:49 pm-1:35 am

3 stops29h 46m

Sao Paulo Guarulhos Intl

Wed 3/4

1:20 am-4:54 pm

2 stops17h 34m

$655

CharlotteSao Paulo

CLT - GRU

CLTGRU

Charlotte Douglas

Sat 4/18

11:12 am-10:30 pm

2 stops34h 18m

Sao Paulo Guarulhos Intl

Fri 4/24

1:20 am-12:40 am

3 stops24h 20m

$666

CharlotteSao Paulo

CLT - VCP

CLTVCP

Charlotte Douglas

Sat 4/4

9:00 pm-5:45 pm

1 stop19h 45m

Sao Paulo Viracopos

Wed 4/8

10:45 pm-2:27 pm

1 stop16h 42m

$673

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from South Carolina to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Sao Paulo
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from South Carolina to Sao Paulo?

    GOL, LATAM Airlines, and United Airlines can get you from South Carolina to Sao Paulo in just under 14h. Your travel time can differ by up to 7h 35m. The distance between South Carolina and Sao Paulo is about 4468 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Sao Paulo?

  • Can I find deals for flights from South Carolina to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Sao Paulo.

  • Can I find deals for business class flights from South Carolina to Sao Paulo?

    Yes. Cheapflights offers flight deals from South Carolina to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Sao Paulo

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.