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Santo Domingo

$266+ Cheap flights from Harrisburg (MDT) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SDQ
Dec 10 — Dec 171
Wed 12/10
Wed 12/17
1 adult, Economy
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Find flight deals from Harrisburg to Santo Domingo

Cheapest flights from Harrisburg to Santo Domingo
Explore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.

This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:00 amMDT - SDQ
2 stops17h 50mAmerican Airlines
Sat 12/134:58 pmSDQ - MDT
2 stops17h 03mAmerican Airlines
Deal found 11/8$346
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:32 pmMDT - SDQ
2 stops15h 56mAmerican Airlines
Sun 12/146:23 pmSDQ - MDT
2 stops17h 19mAmerican Airlines
Deal found 11/8$351
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:32 pmMDT - SDQ
2 stops15h 29mAmerican Airlines
Mon 12/154:58 pmSDQ - MDT
2 stops18h 19mAmerican Airlines
Deal found 11/8$354
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:00 amMDT - SDQ
1 stop7h 42mDelta
Sat 12/133:57 pmSDQ - MDT
1 stop8h 16mDelta
Deal found 11/8$545
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:00 amMDT - SDQ
1 stop7h 42mDelta
Mon 12/153:57 pmSDQ - MDT
1 stop8h 16mDelta
Deal found 11/8$614
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amMDT - SDQ
1 stop7h 42mDelta
Sun 12/143:57 pmSDQ - MDT
1 stop8h 16mDelta
Deal found 11/10$627
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:40 amMDT - SDQ
2 stops11h 00mMultiple Airlines
Sat 1/38:20 amSDQ - MDT
1 stop26h 41mMultiple Airlines
Deal found 11/8$940
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:00 amMDT - SDQ
1 stop7h 42mDelta
Wed 12/33:57 pmSDQ - MDT
1 stop8h 16mDelta
Deal found 11/8$1,107
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:00 amMDT - SDQ
2 stops17h 59mAmerican Airlines
Sat 1/36:00 amSDQ - MDT
2 stops14h 07mAmerican Airlines
Deal found 11/8$1,618

Cheap flight deals from Harrisburg to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$346
(American Airlines)

One-way from

$266
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$661
Provider with most accurate pricing for Harrisburg-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Santo Domingo Las Americas flights.
Search Deals
From Harrisburg to Santo Domingo Las Americas
Search Deals
One-way flight from Harrisburg to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($96 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($43 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from Harrisburg to Santo Domingo that are best for you.

Fly from

Harrisburg

Fly to

Santo Domingo

Route

Depart

Return

Price

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Wed 1/21

5:10 pm-12:21 pm

2 stops18h 11m

Santo Domingo Las Americas

Wed 1/28

1:23 pm-11:50 pm

2 stops11h 27m

$346

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 12/6

7:15 pm-12:28 pm

2 stops16h 13m

Santo Domingo Las Americas

Sat 12/13

6:00 am-12:19 am

2 stops19h 19m

$346

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Mon 12/1

7:23 pm-12:15 pm

2 stops15h 52m

Santo Domingo Las Americas

Wed 12/3

6:23 pm-10:56 am

2 stops17h 33m

$346

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Thu 12/4

5:00 am-11:50 pm

2 stops17h 50m

Santo Domingo Las Americas

Sun 12/14

6:23 pm-10:42 am

2 stops17h 19m

$449

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Thu 1/8

10:42 am-11:26 pm

1 stop11h 44m

Santo Domingo Las Americas

Fri 1/16

6:29 pm-10:17 am

2 stops16h 48m

$542

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 12/6

6:00 am-2:42 pm

1 stop7h 42m

Santo Domingo Las Americas

Sat 12/13

3:57 pm-11:13 pm

1 stop8h 16m

$545

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Wed 1/7

6:25 am-11:26 pm

1 stop16h 01m

$266

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Wed 1/7

6:04 pm-3:35 pm

3 stops44h 31m

$308

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Compare providers for flights from Harrisburg to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Santo Domingo in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Harrisburg-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Harrisburg-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Santo Domingo

What is the cheapest month to book a flight from Harrisburg to Santo Domingo?

Currently, July is the cheapest month in which you can book a flight from Harrisburg to Santo Domingo (average of $259). Flying from Harrisburg to Santo Domingo in May is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated November 10, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Harrisburg to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,045 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Santo Domingo?

    American Airlines can get you from Harrisburg to Santo Domingo in just under 18h 11m. Your travel time can differ by up to . The distance between Harrisburg and Santo Domingo is about 1561 mi.

  • What are the cheapest airlines flying from Harrisburg to Santo Domingo round-trip?

    Flying on Delta is currently your cheapest option to Santo Domingo, with prices starting at $420. Another option worth looking into is American Airlines, starting at $441 round trip. These flights start at 38% lower than the current average price 3 months from now.

  • Can I find deals for flights from Harrisburg to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Santo Domingo.

  • Can I find deals for business class flights from Harrisburg to Santo Domingo?

    Yes. Cheapflights offers flight deals from Harrisburg to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Santo Domingo?

    Currently, July is the cheapest month in which you can book a flight from Harrisburg to Santo Domingo (average of $259). Flying from Harrisburg to Santo Domingo in May is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Harrisburg to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Santo Domingo flights
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Philadelphia to Santiago de los Caballeros flights
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Dulles Intl to Puerto Plata flights
Reagan-National to Puerto Plata flights
Reagan-National to Santiago de los Caballeros flights
Philadelphia to Puerto Plata flights
Harrisburg to Punta Cana flights
Allentown to Punta Cana flights
John F Kennedy Intl to La Romana flights
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Pittsburgh to Puerto Plata flights
Pittsburgh to Santo Domingo flights
Scranton to Punta Cana flights
Pittsburgh to Santiago de los Caballeros flights
State College to Punta Cana flights
Scranton to Santo Domingo flights
Dulles Intl to La Romana flights
Allentown to Puerto Plata flights
Allentown to Santiago de los Caballeros flights
Newark to Nagua flights
LaGuardia to Nagua flights
Harrisburg to Puerto Plata flights
State College to Santo Domingo flights
Philadelphia to Nagua flights
Harrisburg to Santiago de los Caballeros flights
Reagan-National to Nagua flights
Dulles Intl to Nagua flights
Williamsport to Punta Cana flights

Top 2 airlines flying from Harrisburg to Santo Domingo

Discover the top 2 airlines that operate flights from Harrisburg to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$420Average$565FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$441Average$691FlexibilityNo cancel feeOn-time71%

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