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Santo Domingo

$269+ Cheap flights from Harrisburg (MDT) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/29. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SDQ
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Find cheap flights from Harrisburg to Santo Domingo with Cheapflights

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Cheap flight deals from Harrisburg to Santo Domingo

Cheapest flights from Harrisburg to Santo Domingo
Explore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/17:16 pm
MDT
-
SDQ
2 stops17h 44m
American Airlines
Sun 2/86:29 pm
SDQ
-
MDT
2 stops17h 25m
American Airlines
Deal found 1/24$325
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:59 pm
MDT
-
SDQ
2 stops16h 21m
American Airlines
Sun 5/244:26 pm
SDQ
-
MDT
2 stops17h 45m
American Airlines
Deal found 1/26$337
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:11 pm
MDT
-
SDQ
1 stop12h 56m
Multiple Airlines
Thu 4/233:37 pm
SDQ
-
MDT
1 stop25h 49m
Multiple Airlines
Deal found 1/25$383
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:21 pm
MDT
-
SDQ
1 stop13h 18m
Multiple Airlines
Sat 2/213:32 pm
SDQ
-
MDT
2 stops19h 19m
Multiple Airlines
Deal found 1/25$418
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:33 am
MDT
-
SDQ
2 stops16h 20m
American Airlines
Sat 2/215:07 pm
SDQ
-
MDT
2 stops17h 14m
American Airlines
Deal found 1/25$419
This Faresmojo deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
MDT
-
SDQ
1 stop7h 21m
JetBlue
Sun 5/242:45 pm
SDQ
-
MDT
1 stop8h 56m
JetBlue
Deal found 1/26$420
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:56 am
MDT
-
SDQ
2 stops12h 56m
American Airlines
Thu 4/232:25 pm
SDQ
-
MDT
2 stops19h 06m
American Airlines
Deal found 1/25$434
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:26 pm
MDT
-
SDQ
1 stop8h 12m
Multiple Airlines
Wed 3/182:30 pm
SDQ
-
MDT
2 stops30h 58m
Multiple Airlines
Deal found 1/25$441

Find flight deals from Harrisburg to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$325
(American Airlines)

One-way from

$269
(Frontier)

Popular in

July

Cheapest in

October

Average price

$577
Provider with most accurate pricing for Harrisburg-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Santo Domingo Las Americas flights.
Search Deals
From Harrisburg to Santo Domingo Las Americas
Search Deals
One-way flight from Harrisburg to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($129 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Harrisburg to Santo Domingo that are best for you.

Fly from

Harrisburg

Fly to

Santo Domingo

Route

Depart

Return

Price

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Fri 5/8

4:59 pm-9:20 am

2 stops16h 21m

Santo Domingo Las Americas

Sun 5/24

4:26 pm-10:11 am

2 stops17h 45m

$337

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Thu 4/9

9:11 pm-10:07 am

1 stop12h 56m

Santo Domingo Las Americas

Thu 4/23

3:37 pm-5:26 pm

1 stop25h 49m

$383

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 2/14

7:21 pm-9:39 am

1 stop13h 18m

Santo Domingo Las Americas

Sat 2/21

3:32 pm-9:51 am

2 stops19h 19m

$418

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sun 2/15

5:06 pm-10:00 am

2 stops15h 54m

Santo Domingo Las Americas

Sat 2/21

5:07 pm-9:21 am

2 stops17h 14m

$419

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 2/14

6:33 am-11:53 pm

2 stops16h 20m

Santo Domingo Las Americas

Sat 2/21

5:07 pm-9:21 am

2 stops17h 14m

$419

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Thu 7/2

6:00 am-1:21 pm

1 stop7h 21m

Santo Domingo Las Americas

Mon 7/6

2:46 pm-11:41 pm

1 stop8h 55m

$420

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Fri 5/8

6:00 am-1:21 pm

1 stop7h 21m

Santo Domingo Las Americas

Sun 5/24

2:45 pm-11:41 pm

1 stop8h 56m

$420

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Thu 4/9

9:56 am-10:52 pm

2 stops12h 56m

Santo Domingo Las Americas

Thu 4/23

2:25 pm-9:31 am

2 stops19h 06m

$434

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Thu 4/9

6:40 am-10:52 pm

2 stops16h 12m

Santo Domingo Las Americas

Fri 4/24

6:00 am-12:31 am

2 stops18h 31m

$434

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sun 3/29

10:13 pm-9:41 am

1 stop11h 28m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 11 results
1
2

Compare providers for flights from Harrisburg to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Santo Domingo in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Santo Domingo

What is the cheapest month to book a flight from Harrisburg to Santo Domingo?

Currently, July is the cheapest month in which you can book a flight from Harrisburg to Santo Domingo (average of $259). Flying from Harrisburg to Santo Domingo in May is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Harrisburg to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated January 26, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Harrisburg to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,111 reviews
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,189 reviews
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Santo Domingo?

    American Airlines can get you from Harrisburg to Santo Domingo in just under 16h 21m. Your travel time can differ by up to . The distance between Harrisburg and Santo Domingo is about 1561 mi.

  • What are the cheapest airlines flying from Harrisburg to Santo Domingo round-trip?

    Flying on American Airlines is currently your cheapest option to Santo Domingo, with prices starting at $399. Another option worth looking into is Delta, starting at $464 round trip. These flights start at 39% lower than the current average price 3 months from now.

  • Can I find deals for flights from Harrisburg to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Santo Domingo.

  • Can I find deals for business class flights from Harrisburg to Santo Domingo?

    Yes. Cheapflights offers flight deals from Harrisburg to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Santo Domingo?

    Currently, July is the cheapest month in which you can book a flight from Harrisburg to Santo Domingo (average of $259). Flying from Harrisburg to Santo Domingo in May is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Harrisburg to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Harrisburg to Santo Domingo

Discover the top 2 airlines that operate flights from Harrisburg to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$399Average$602FlexibilityNo cancel feeOn-time71%
DeltaCheapest$464Average$608FlexibilityNo cancel feeOn-timeN/A

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