$195+ Cheap flights from Harrisburg (MDT) to Santo Domingo (SDQ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SDQ
Nov 7 — Nov 141
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to Santo Domingo
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One-way
Cheapest flights from Harrisburg to Santo DomingoExplore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
Explore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:46 pm -
2 stops15h 19m
Tue 12/12:50 pm -
1 stop7h 26m
Deal found 10/4![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:18 pm -
2 stops21h 04m
Fri 11/62:55 pm -
1 stop19h 16m
Deal found 10/6![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:05 pm -
1 stop17h 48m
Sun 11/156:00 am -
2 stops15h 59m
Deal found 10/6![American Airlines logo]()
$476
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:06 pm -
1 stop17h 29m
Wed 10/2810:27 am -
2 stops11h 52m
Deal found 10/6![American Airlines logo]()
$505
Best flights from Harrisburg to Santo DomingoDiscover carefully curated flight deals from Harrisburg to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
Discover carefully curated flight deals from Harrisburg to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:46 pm -
2 stops15h 19m
Tue 12/12:50 pm -
1 stop7h 26m
Deal found 10/4![American Airlines logo]()
$405
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:54 pm -
2 stops28h 52m
Wed 10/285:00 am -
2 stops13h 57m
Deal found 10/4![United Airlines logo]()
$599
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:20 am -
2 stops16h 26m
Fri 12/116:00 am -
2 stops15h 54m
Deal found 10/7![United Airlines logo]()
$735
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:15 am -
2 stops16h 31m
Sun 11/292:53 pm -
2 stops19h 52m
Deal found 10/8![United Airlines logo]()
$1,115
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:00 am -
1 stop7h 32m
Sun 1/313:40 pm -
1 stop8h 58m
Deal found 10/6![Delta logo]()
$2,476
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:17 am -
2 stops16h 29m
Sun 1/312:53 pm -
3 stops30h 56m
Deal found 10/6![United Airlines logo]()
$1,156
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:00 am -
2 stops15h 51m
Sun 1/34:59 pm -
2 stops17h 16m
Deal found 10/8![American Airlines logo]()
$1,738
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:59 pm -
2 stops54h 46m
Sun 1/32:53 pm -
2 stops31h 22m
Deal found 10/4![United Airlines logo]()
$1,547
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:30 am -
2 stops12h 16m
Fri 11/66:00 am -
3 stops13h 36m
Deal found 10/6![United Airlines logo]()
$2,310
Last-minute flights from Harrisburg to Santo DomingoDiscover last-minute flight deals from Harrisburg to Santo Domingo. Data last updated October 8, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to Santo Domingo. Data last updated October 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:06 pm -
1 stop17h 29m
Wed 10/2810:27 am -
2 stops11h 52m
Deal found 10/6![American Airlines logo]()
$505
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:18 pm -
2 stops21h 04m
Fri 11/62:55 pm -
1 stop19h 16m
Deal found 10/6![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:05 pm -
1 stop17h 48m
Sun 11/156:00 am -
2 stops15h 59m
Deal found 10/6![American Airlines logo]()
$476
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:46 pm -
2 stops15h 19m
Tue 12/12:50 pm -
1 stop7h 26m
Deal found 10/4![American Airlines logo]()
$405
One-way flights from Harrisburg to Santo DomingoSearch for one-way flight options from Harrisburg to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
Search for one-way flight options from Harrisburg to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/313:07 pm -
1 stop21h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![American Airlines logo]()
$195
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:13 pm -
2 stops16h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![United Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:05 pm -
1 stop17h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![American Airlines logo]()
$306
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:13 pm -
2 stops16h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![United Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:15 am -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:20 am -
2 stops39h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![United Airlines logo]()
$414
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:53 am -
3 stops34h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:21 pm -
3 stops28h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$492
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/241:21 pm -
3 stops21h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$504
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:01 pm -
3 stops23h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$540
Find flight deals from Harrisburg to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 8, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $405 (American Airlines) |
One-way from | $195 (American Airlines) |
Popular in | December |
Cheapest in | October |
Average price | $405 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
Use the filters below to find and compare flights from Harrisburg to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Thu 12/31
5:40 pm-9:48 am
2 stops15h 08m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$258
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Fri 11/6
8:13 pm-1:41 pm
2 stops16h 28m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$274
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Thu 11/19
8:13 pm-1:41 pm
2 stops16h 28m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$274
Quickest round-trip
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Thu 11/19
6:15 am-1:50 pm
1 stop6h 35m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$339
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Mon 11/23
5:46 pm-10:05 am
2 stops15h 19m
Santo Domingo Las Americas
Tue 12/1
2:50 pm-9:16 pm
1 stop7h 26m
$405
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Thu 12/24
6:20 am-10:45 pm
2 stops39h 25m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$414
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Fri 11/6
9:53 am-9:45 pm
3 stops34h 52m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$461
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Thu 12/31
1:21 pm-7:04 pm
3 stops28h 43m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$492
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Thu 12/24
1:21 pm-11:42 am
3 stops21h 21m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$504
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Thu 11/19
4:01 pm-4:29 pm
3 stops23h 28m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$540
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Harrisburg to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Santo Domingo in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-Santo Domingo flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Harrisburg-Santo Domingo flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Harrisburg-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-Santo Domingo flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Harrisburg with our price prediction graph.
MDT-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to Santo Domingo
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 8, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Harrisburg to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Complete your trip
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Harrisburg and Santo Domingo flights
Browse other Harrisburg and Santo Domingo flight options. Last updated on October 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santo Domingo
Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 8, 2026.
Top 2 airlines flying from Harrisburg to Santo Domingo
Discover the top 2 airlines that operate flights from Harrisburg to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$460 | Average$780 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$478 | Average$655 | FlexibilityNo cancel fee | On-timeN/A |