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Santo Domingo

$401+ Cheap flights from Harrisburg (MDT) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SDQ
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Harrisburg to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2025.

Round-trip from

$470
(American Airlines)

One-way from

$401
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$667
From Harrisburg to Santo Domingo Las Americas
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One-way flight from Harrisburg to Santo Domingo Las Americas
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Highest demand for flights based on searches. 21% potential increase in price ($195 potential increase over avg. RT price).
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Cheapest flight prices on average. 11% potential price decrease ($77 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Harrisburg to Santo Domingo

Cheapest flights from Harrisburg to Santo Domingo
Explore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/156:30 pmMDT - SDQ
2 stops16h 45mAmerican Airlines
Mon 9/2212:15 pmSDQ - MDT
2 stops10h 27mAmerican Airlines
Deal found 8/18$470
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/217:30 amMDT - SDQ
2 stops13h 00mAmerican Airlines
Fri 9/264:20 pmSDQ - MDT
2 stops20h 16mAmerican Airlines
Deal found 8/17$483
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:15 amMDT - SDQ
2 stops19h 35mUnited Airlines
Wed 10/812:47 pmSDQ - MDT
2 stops20h 42mUnited Airlines
Deal found 8/16$614
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/18:15 amMDT - SDQ
2 stops14h 31mUnited Airlines
Sun 11/94:18 pmSDQ - MDT
2 stops18h 17mUnited Airlines
Deal found 8/16$693
This Priceline deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:00 pmMDT - SDQ
1 stop13h 11mFrontier
Sat 1/37:55 pmSDQ - MDT
1 stop24h 10mFrontier
Deal found 8/17$826
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/216:00 amMDT - SDQ
1 stop7h 24mDelta
Fri 9/262:50 pmSDQ - MDT
1 stop8h 56mDelta
Deal found 8/17$829
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:00 amMDT - SDQ
1 stop7h 41mDelta
Tue 10/212:56 pmSDQ - MDT
1 stop8h 12mDelta
Deal found 8/15$884
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amMDT - SDQ
1 stop7h 57mDelta
Mon 12/154:22 pmSDQ - MDT
1 stop8h 16mDelta
Deal found 8/15$937
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/292:52 pmMDT - SDQ
1 stop9h 47mMultiple Airlines
Sun 1/43:30 pmSDQ - MDT
2 stops23h 37mMultiple Airlines
Deal found 8/17$1,132
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:00 pmMDT - SDQ
2 stops23h 06mUnited Airlines
Mon 1/52:53 pmSDQ - MDT
2 stops23h 56mUnited Airlines
Deal found 8/16$1,152
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:10 amMDT - SDQ
2 stops11h 40mAmerican Airlines
Sun 1/46:45 amSDQ - MDT
2 stops15h 58mAmerican Airlines
Deal found 8/17$1,161

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Harrisburg to Santo Domingo that are best for you.

Fly from

Harrisburg

Fly to

Santo Domingo

Route

Depart

Return

Price

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Mon 9/15

5:30 am-3:20 pm

2 stops9h 50m

Santo Domingo Las Americas

Mon 9/22

7:00 am-10:42 pm

2 stops15h 42m

$470

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 10/11

9:33 am-8:30 pm

2 stops10h 57m

Santo Domingo Las Americas

Tue 10/21

10:25 am-9:47 pm

2 stops11h 22m

$470

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sun 9/21

7:30 am-8:30 pm

2 stops13h 00m

Santo Domingo Las Americas

Fri 9/26

4:20 pm-12:36 pm

2 stops20h 16m

$483

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Wed 10/1

6:15 am-1:50 am

2 stops19h 35m

Santo Domingo Las Americas

Wed 10/8

12:47 pm-9:29 am

2 stops20h 42m

$614

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 2/14

5:00 am-8:45 pm

2 stops14h 45m

Santo Domingo Las Americas

Sat 2/21

6:45 am-7:28 pm

2 stops13h 43m

$618

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 11/1

8:15 am-10:46 pm

2 stops14h 31m

Santo Domingo Las Americas

Sun 11/9

4:18 pm-9:35 am

2 stops18h 17m

$693

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sun 12/28

8:00 pm-10:11 am

1 stop13h 11m

Santo Domingo Las Americas

Sat 1/3

7:55 pm-7:05 pm

1 stop24h 10m

$826

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sun 9/21

6:00 am-1:24 pm

1 stop7h 24m

Santo Domingo Las Americas

Fri 9/26

2:50 pm-11:46 pm

1 stop8h 56m

$829

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 10/11

6:00 am-1:41 pm

1 stop7h 41m

Santo Domingo Las Americas

Tue 10/21

2:56 pm-11:08 pm

1 stop8h 12m

$884

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Wed 12/10

6:00 am-2:57 pm

1 stop7h 57m

Santo Domingo Las Americas

Mon 12/15

4:22 pm-11:38 pm

1 stop8h 16m

$937

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 11 results
1
2

Best time to book a flight from Harrisburg to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Santo Domingo

What is the cheapest month to book a flight from Harrisburg to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Harrisburg to Santo Domingo (average of $362). Flying from Harrisburg to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to SDQ?

Find hourly flight availability from Harrisburg to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

When flying from Harrisburg to Santo Domingo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated August 18, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Harrisburg to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Santo Domingo?

    American Airlines and United Airlines can get you from Harrisburg to Santo Domingo in just under 9h 50m. Your travel time can differ by up to 9h 45m. The distance between Harrisburg and Santo Domingo is about 1561 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Harrisburg to Santo Domingo round-trip?

    Flying on American Airlines is currently your cheapest option to Santo Domingo, with prices starting at $414. Another option worth looking into is Delta, starting at $420 round trip. These flights start at 43% lower than the current average price 3 months from now.

  • Can I find deals for flights from Harrisburg to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Santo Domingo.

  • Can I find deals for business class flights from Harrisburg to Santo Domingo?

    Yes. Cheapflights offers flight deals from Harrisburg to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Harrisburg to Santo Domingo (average of $362). Flying from Harrisburg to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Harrisburg to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Harrisburg to Santo Domingo

Discover the top 2 airlines that operate flights from Harrisburg to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$414Average$764FlexibilityNo cancel feeOn-time71%
DeltaCheapest$420Average$557FlexibilityNo cancel feeOn-timeN/A

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