$221+ Cheap flights from Harrisburg (MDT) to Santo Domingo (SDQ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SDQ
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to Santo Domingo
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Cheapest flights from Harrisburg to Santo DomingoExplore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Harrisburg to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:20 pm -
2 stops17h 34m
Thu 12/172:36 pm -
1 stop9h 13m
Deal found 11/1![American Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:46 am -
2 stops11h 07m
Wed 12/97:00 am -
2 stops16h 40m
Deal found 11/3![American Airlines logo]()
$554
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:46 am -
1 stop28h 31m
Tue 12/224:59 pm -
2 stops17h 16m
Deal found 10/31![American Airlines logo]()
$610
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:15 am -
2 stops14h 31m
Mon 11/166:00 am -
2 stops28h 53m
Deal found 11/1![United Airlines logo]()
$627
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:56 pm -
2 stops18h 23m
Mon 11/162:55 pm -
1 stop23h 34m
Deal found 11/4![American Airlines logo]()
$631
Best flights from Harrisburg to Santo DomingoDiscover carefully curated flight deals from Harrisburg to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Harrisburg to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:56 am -
1 stop26h 21m
Wed 12/92:22 pm -
1 stop7h 45m
Deal found 11/3![American Airlines logo]()
$556
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/410:25 am -
3 stops27h 41m
Fri 2/196:00 am -
2 stops28h 53m
Deal found 11/1![United Airlines logo]()
$641
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/186:20 am -
2 stops16h 26m
Thu 1/214:18 pm -
2 stops18h 27m
Deal found 11/3![United Airlines logo]()
$770
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:11 am -
2 stops11h 03m
Thu 12/246:00 am -
2 stops12h 19m
Deal found 11/2![American Airlines logo]()
$915
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:00 am -
1 stop7h 30m
Tue 12/223:55 pm -
1 stop9h 01m
Deal found 11/3![Delta logo]()
$2,464
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/212:59 pm -
2 stops23h 07m
Thu 12/246:00 am -
2 stops33h 00m
Deal found 11/3![United Airlines logo]()
$1,171
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/202:59 pm -
2 stops23h 07m
Sun 12/274:18 pm -
2 stops18h 32m
Deal found 11/4![United Airlines logo]()
$1,181
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:59 pm -
2 stops31h 47m
Sun 1/36:00 am -
2 stops33h 00m
Deal found 11/2![United Airlines logo]()
$1,698
Last-minute flights from Harrisburg to Santo DomingoDiscover last-minute flight deals from Harrisburg to Santo Domingo. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to Santo Domingo. Data last updated November 4, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:15 am -
2 stops14h 31m
Mon 11/166:00 am -
2 stops28h 53m
Deal found 11/1![United Airlines logo]()
$627
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:40 pm -
2 stops20h 39m
Mon 11/167:19 pm -
2 stops16h 01m
Deal found 11/4![American Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:46 am -
2 stops11h 07m
Wed 12/97:00 am -
2 stops16h 40m
Deal found 11/3![American Airlines logo]()
$554
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:20 pm -
2 stops17h 34m
Thu 12/172:36 pm -
1 stop9h 13m
Deal found 11/1![American Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:46 am -
1 stop28h 31m
Tue 12/224:59 pm -
2 stops17h 16m
Deal found 10/31![American Airlines logo]()
$610
One-way flights from Harrisburg to Santo DomingoSearch for one-way flight options from Harrisburg to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Harrisburg to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:40 pm -
2 stops15h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$221
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/119:40 am -
1 stop27h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![American Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:34 am -
2 stops14h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![American Airlines logo]()
$249
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/112:59 pm -
3 stops23h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![United Airlines logo]()
$294
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:03 am -
2 stops39h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![United Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:20 pm -
2 stops17h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![American Airlines logo]()
$304
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:00 am -
2 stops15h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![United Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:35 am -
2 stops27h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![United Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:18 pm -
1 stop17h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![American Airlines logo]()
$440
Find flight deals from Harrisburg to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $525 (American Airlines) |
One-way from | $221 (American Airlines) |
Popular in | December |
Cheapest in | October |
Average price | $825 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Harrisburg to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Thu 12/31
5:40 pm-9:48 am
2 stops15h 08m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$221
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Thu 11/12
10:12 am-9:43 pm
2 stops10h 31m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$249
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Mon 1/11
2:59 pm-3:06 pm
3 stops23h 07m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$294
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Tue 12/29
6:03 am-10:45 pm
2 stops39h 42m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$295
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Fri 1/1
6:00 am-10:45 pm
2 stops15h 45m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$333
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Mon 12/7
2:22 pm-1:17 pm
1 stop21h 55m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$393
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Tue 12/1
10:35 am-3:06 pm
2 stops27h 31m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$397
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Sun 12/20
7:18 pm-1:36 pm
1 stop17h 18m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$440
Quickest round-trip
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Fri 1/1
6:00 am-2:30 pm
1 stop7h 30m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$535
HarrisburgSanto Domingo
MDT Harrisburg - SDQ Santo Domingo Las Americas
MDTSDQ
Harrisburg
Wed 12/2
9:56 am-1:17 pm
1 stop26h 21m
Santo Domingo Las Americas
Wed 12/9
2:22 pm-9:07 pm
1 stop7h 45m
$556
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Harrisburg to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Santo Domingo in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-Santo Domingo flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Harrisburg-Santo Domingo flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Harrisburg-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-Santo Domingo flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Harrisburg with our price prediction graph.
MDT-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to Santo Domingo
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated November 4, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Harrisburg to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Complete your trip
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Harrisburg and Santo Domingo flights
Browse other Harrisburg and Santo Domingo flight options. Last updated on November 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santo Domingo
Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Top 2 airlines flying from Harrisburg to Santo Domingo
Discover the top 2 airlines that operate flights from Harrisburg to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$460 | Average$780 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$478 | Average$655 | FlexibilityNo cancel fee | On-timeN/A |