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Santiago de los Caballeros

$188+ Cheap flights from Jacksonville (JAX) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STI
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Jacksonville to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$397
(Delta)

One-way from

$272
(Delta)

Popular in

January

Cheapest in

March
From Jacksonville to Santiago de los Caballeros
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One-way flight from Jacksonville to Santiago de los Caballeros
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Highest demand for flights based on searches. 12% potential increase in price ($93 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($28 potential savings vs. average RT price).
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Find flight deals from Jacksonville to Santiago de los Caballeros

Cheapest flights from Jacksonville to Santiago de los Caballeros
Explore the most affordable flight options available from Jacksonville to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2412:14 pmJAX - STI
1 stop12h 10mDelta
Tue 10/286:00 amSTI - JAX
1 stop10h 37mDelta
Deal found 9/14$397
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:05 amJAX - STI
1 stop12h 01mDelta
Tue 11/186:35 amSTI - JAX
1 stop11h 09mDelta
Deal found 9/15$398
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:20 pmJAX - STI
2 stops18h 53mAmerican Airlines
Tue 10/281:14 pmSTI - JAX
1 stop10h 45mAmerican Airlines
Deal found 9/14$401
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:58 amJAX - STI
1 stop4h 15mAmerican Airlines
Tue 11/187:00 amSTI - JAX
2 stops9h 36mAmerican Airlines
Deal found 9/14$403
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:00 amJAX - STI
1 stop6h 13mAmerican Airlines
Mon 10/201:14 pmSTI - JAX
1 stop20h 21mAmerican Airlines
Deal found 9/15$404
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:20 pmJAX - STI
2 stops18h 53mAmerican Airlines
Tue 11/47:00 amSTI - JAX
1 stop16h 16mAmerican Airlines
Deal found 9/14$412
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:12 pmJAX - STI
1 stop9h 16mJetBlue
Mon 10/273:43 amSTI - JAX
1 stop16h 54mJetBlue
Deal found 9/14$421
This SmartFares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:08 amJAX - STI
1 stop12h 26mJetBlue
Mon 11/34:41 amSTI - JAX
1 stop16h 56mJetBlue
Deal found 9/14$428
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2111:30 amJAX - STI
1 stop14h 56mJetBlue
Mon 11/174:41 amSTI - JAX
1 stop16h 56mJetBlue
Deal found 9/14$433
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:13 pmJAX - STI
1 stop9h 08mJetBlue
Thu 10/27:14 pmSTI - JAX
1 stop27h 57mJetBlue
Deal found 9/14$471

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Jacksonville to Santiago de los Caballeros that are best for you.

Fly from

Jacksonville

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Fri 10/24

12:14 pm-12:24 am

1 stop12h 10m

Santiago de los Caballeros

Tue 10/28

6:00 am-4:37 pm

1 stop10h 37m

$397

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Thu 10/30

7:05 am-12:24 am

1 stop17h 19m

Santiago de los Caballeros

Tue 11/4

7:00 am-10:29 pm

1 stop16h 29m

$398

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Tue 10/21

7:05 am-7:06 pm

1 stop12h 01m

Santiago de los Caballeros

Tue 11/18

6:35 am-4:44 pm

1 stop11h 09m

$398

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Mon 10/13

7:58 am-12:13 pm

1 stop4h 15m

Santiago de los Caballeros

Mon 10/20

1:14 pm-9:55 am

2 stops20h 41m

$401

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Fri 10/24

5:20 pm-12:13 pm

2 stops18h 53m

Santiago de los Caballeros

Tue 10/28

1:14 pm-11:59 pm

1 stop10h 45m

$401

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Tue 10/21

7:58 am-12:13 pm

1 stop4h 15m

Santiago de los Caballeros

Tue 11/18

7:00 am-3:36 pm

2 stops9h 36m

$403

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Mon 12/8

7:25 am-8:33 pm

2 stops12h 08m

$188

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Mon 12/8

12:52 pm-5:06 pm

3 stops51h 14m

$253

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Thu 11/20

7:35 am-7:36 pm

1 stop11h 01m

$272

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Mon 12/15

7:25 am-8:33 pm

2 stops12h 08m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 16 results
1
2

Best time to book a flight from Jacksonville to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Santiago de los Caballeros

What is the cheapest month to book a flight from Jacksonville to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Jacksonville to Santiago de los Caballeros (average of $347). Flying from Jacksonville to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to STI?

Find hourly flight availability from Jacksonville to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

It’s optimal to fly from Jacksonville to Santiago de los Caballeros in the morning. By choosing this option you can save up to 25% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated September 16, 2025.
See what other customers who have flown with American Airlines from Jacksonville to Santiago de los Caballeros have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Jacksonville to Santiago de los Caballeros?

    Departing from Jacksonville to Santiago de los Caballeros will take you 12h 10m. The distance from Jacksonville to Santiago de los Caballeros is about 1032 mi.

  • What is the cheapest airline to fly from Jacksonville to Santiago de los Caballeros round-trip?

    According to our current data, American Airlines ($437), offers the cheapest pricing from Jacksonville to Santiago de los Caballeros. Users have found that American Airlines is 30% cheaper than the other options available to this destination.

  • Can I find deals for flights from Jacksonville to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Santiago de los Caballeros.

  • Can I find deals for business class flights from Jacksonville to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Jacksonville to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from Jacksonville to Santiago de los Caballeros (average of $347). Flying from Jacksonville to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Jacksonville to Santiago de los Caballeros

Discover the top airline that operate flights from Jacksonville to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$437Average$649FlexibilityNo cancel feeOn-time71%

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