$294+ Cheap flights from Jacksonville (JAX) to Santiago de los Caballeros (STI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STI
Jun 5 — Jun 121
Round-trip
1 adult, Economy
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Find cheap flights from Jacksonville to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to Santiago de los Caballeros
Cheapest
Best
Last-minute
One-way
Cheapest flights from Jacksonville to Santiago de los CaballerosExplore the most affordable flight options available from Jacksonville to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
Explore the most affordable flight options available from Jacksonville to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
This Expedia deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/253:52 pm
JAX
- STI
1 stop18h 07m
Frontier
Sun 8/211:14 am
STI
- JAX
1 stop25h 05m
Frontier
Deal found 5/5![Frontier logo]()
$409
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am
JAX
- STI
1 stop13h 06m
Delta
Tue 10/208:31 pm
STI
- JAX
1 stop14h 13m
Delta
Deal found 5/5![Delta logo]()
$448
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am
JAX
- STI
1 stop12h 06m
Delta
Mon 10/198:31 pm
STI
- JAX
1 stop14h 13m
Delta
Deal found 5/5![Delta logo]()
$468
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:00 am
JAX
- STI
2 stops14h 28m
American Airlines
Tue 7/219:00 am
STI
- JAX
1 stop24h 27m
American Airlines
Deal found 5/5![American Airlines logo]()
$477
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:41 pm
JAX
- STI
1 stop19h 41m
American Airlines
Mon 8/313:31 pm
STI
- JAX
1 stop23h 58m
American Airlines
Deal found 5/4![American Airlines logo]()
$500
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:56 pm
JAX
- STI
2 stops18h 48m
American Airlines
Sun 8/23:44 pm
STI
- JAX
2 stops21h 08m
American Airlines
Deal found 5/5![American Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:28 pm
JAX
- STI
1 stop26h 44m
American Airlines
Thu 6/257:04 am
STI
- JAX
1 stop10h 44m
American Airlines
Deal found 5/4![American Airlines logo]()
$517
Best flights from Jacksonville to Santiago de los CaballerosDiscover carefully curated flight deals from Jacksonville to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
Discover carefully curated flight deals from Jacksonville to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am
JAX
- STI
1 stop13h 06m
Delta
Tue 10/208:31 pm
STI
- JAX
1 stop14h 13m
Delta
Deal found 5/5![Delta logo]()
$448
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:00 am
JAX
- STI
2 stops14h 28m
American Airlines
Tue 7/219:00 am
STI
- JAX
1 stop24h 27m
American Airlines
Deal found 5/6![American Airlines logo]()
$506
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:30 am
JAX
- STI
2 stops11h 36m
Delta
Tue 10/208:31 pm
STI
- JAX
1 stop14h 13m
Delta
Deal found 5/5![Delta logo]()
$453
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am
JAX
- STI
1 stop13h 06m
Delta
Mon 10/198:31 pm
STI
- JAX
1 stop18h 13m
Delta
Deal found 5/5![Delta logo]()
$468
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:00 am
JAX
- STI
2 stops14h 12m
American Airlines
Thu 6/253:39 pm
STI
- JAX
2 stops19h 30m
American Airlines
Deal found 5/4![American Airlines logo]()
$543
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:30 am
JAX
- STI
2 stops10h 36m
Delta
Mon 10/198:31 pm
STI
- JAX
2 stops13h 50m
Delta
Deal found 5/5![Delta logo]()
$473
Last-minute flights from Jacksonville to Santiago de los CaballerosDiscover last-minute flight deals from Jacksonville to Santiago de los Caballeros. Data last updated May 6, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to Santiago de los Caballeros. Data last updated May 6, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:12 pm
JAX
- STI
2 stops18h 11m
American Airlines
Mon 6/13:38 pm
STI
- JAX
1 stop8h 21m
American Airlines
Deal found 5/5![American Airlines logo]()
$602
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
JAX
- STI
1 stop6h 23m
American Airlines
Tue 5/191:32 pm
STI
- JAX
1 stop10h 27m
American Airlines
Deal found 5/5![American Airlines logo]()
$596
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:24 pm
JAX
- STI
1 stop12h 35m
Delta
Tue 5/196:00 am
STI
- JAX
1 stop15h 53m
Delta
Deal found 5/6![Delta logo]()
$616
This Justfly.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:55 pm
JAX
- STI
1 stop12h 25m
JetBlue
Sun 5/315:01 am
STI
- JAX
1 stop8h 21m
JetBlue
Deal found 5/6![JetBlue logo]()
$598
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
JAX
- STI
1 stop15h 13m
American Airlines
Tue 6/309:07 am
STI
- JAX
1 stop8h 41m
American Airlines
Deal found 5/3![American Airlines logo]()
$551
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:28 pm
JAX
- STI
1 stop26h 44m
American Airlines
Thu 6/257:04 am
STI
- JAX
1 stop10h 44m
American Airlines
Deal found 5/4![American Airlines logo]()
$517
This Expedia deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/219:45 am
JAX
- STI
1 stop22h 15m
Multiple Airlines
Sun 6/2811:09 am
STI
- JAX
1 stop25h 13m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$609
One-way flights from Jacksonville to Santiago de los CaballerosSearch for one-way flight options from Jacksonville to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
Search for one-way flight options from Jacksonville to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
This JetBlue deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:55 pm
JAX
- STI
1 stop12h 25m
JetBlue
Deal found 5/4![JetBlue logo]()
$294
This JetBlue deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:45 am
JAX
- STI
1 stop13h 14m
JetBlue
Deal found 5/4![JetBlue logo]()
$336
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
JAX
- STI
1 stop6h 23m
American Airlines
Deal found 5/5![American Airlines logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:48 pm
JAX
- STI
3 stops23h 02m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$595
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/319:20 am
JAX
- STI
2 stops37h 32m
United Airlines
Deal found 5/4![United Airlines logo]()
$1,822
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3011:18 am
JAX
- STI
2 stops11h 34m
United Airlines
Deal found 5/4![United Airlines logo]()
$2,221
Find flight deals from Jacksonville to Santiago de los Caballeros
Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 6, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $409 (Expedia) |
One-way from | $294 (JetBlue) |
Popular in | December |
Cheapest in | March |
Average price | $755 |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Jacksonville to Santiago de los Caballeros that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleSantiago de los Caballeros
JAX - STI
JAXSTI
Jacksonville
Tue 10/13
6:00 am-7:06 pm
1 stop13h 06m
Santiago de los Caballeros
Tue 10/20
8:31 pm-10:44 am
1 stop14h 13m
$448
JacksonvilleSantiago de los Caballeros
JAX - STI
JAXSTI
Jacksonville
Wed 10/14
7:30 am-7:06 pm
2 stops11h 36m
Santiago de los Caballeros
Tue 10/20
8:31 pm-10:44 am
1 stop14h 13m
$453
JacksonvilleSantiago de los Caballeros
JAX - STI
JAXSTI
Jacksonville
Wed 10/14
6:00 am-7:06 pm
1 stop13h 06m
Santiago de los Caballeros
Mon 10/19
8:31 pm-2:44 pm
1 stop18h 13m
$468
Quickest round-trip
JacksonvilleSantiago de los Caballeros
JAX - STI
JAXSTI
Jacksonville
Tue 10/13
8:30 am-7:06 pm
2 stops10h 36m
Santiago de los Caballeros
Mon 10/19
8:31 pm-10:21 am
2 stops13h 50m
$473
JacksonvilleSantiago de los Caballeros
JAX - STI
JAXSTI
Jacksonville
Thu 7/16
7:00 am-9:28 pm
2 stops14h 28m
Santiago de los Caballeros
Tue 7/21
9:00 am-9:27 am
1 stop24h 27m
$506
JacksonvilleSantiago de los Caballeros
JAX - STI
JAXSTI
Jacksonville
Thu 6/18
7:00 am-9:12 pm
2 stops14h 12m
Santiago de los Caballeros
Thu 6/25
3:39 pm-11:09 am
2 stops19h 30m
$543
Cheapest one-way
JacksonvilleSantiago de los Caballeros
JAX - STI
JAXSTI
Jacksonville
Sat 5/30
8:55 pm-9:20 am
1 stop12h 25m
$294
Quickest one-way
JacksonvilleSantiago de los Caballeros
JAX - STI
JAXSTI
Jacksonville
Fri 5/15
6:00 am-12:23 pm
1 stop6h 23m
$395
JacksonvilleSantiago de los Caballeros
JAX - STI
JAXSTI
Jacksonville
Fri 5/15
3:48 pm-2:50 pm
3 stops23h 02m
$595
JacksonvilleSantiago de los Caballeros
JAX - STI
JAXSTI
Jacksonville
Sat 5/30
11:18 am-10:52 pm
2 stops11h 34m
$2,221
Sorted by cheapest first
Compare providers for flights from Jacksonville to Santiago de los Caballeros
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to Santiago de los Caballeros in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Jacksonville-Santiago de los Caballeros flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Jacksonville-Santiago de los Caballeros flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Jacksonville-Santiago de los Caballeros flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Jacksonville-Santiago de los Caballeros flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Jacksonville to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Jacksonville with our price prediction graph.
JAX-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to Santiago de los Caballeros
Reviews of airlines servicing Santiago de los Caballeros
Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated May 6, 2026.
See what other customers who have flown with American Airlines from Jacksonville to Santiago de los Caballeros have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Overall
7.1
Entertainment
6.9
Boarding
7.5
Crew
7.9
Comfort
7.2
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Food
6.4
Overall
7.1
Entertainment
6.9
Boarding
7.5
Crew
7.9
Comfort
7.2
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Santiago de los Caballeros flight routes
Alternative routes for Jacksonville to Santiago de los Caballeros
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Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to Santiago de los Caballeros by cabin class
Find flights from Jacksonville to Santiago de los Caballeros, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and Santiago de los Caballeros flights
Browse other Jacksonville and Santiago de los Caballeros flight options. Last updated on May 6, 2026.
Other flights from Jacksonville
Browse through other flights departing from Jacksonville. Flights are based on user searches made on Cheapflights and were last updated on May 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 6, 2026.
Top airline flying from Jacksonville to Santiago de los Caballeros
Discover the top airline that operate flights from Jacksonville to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$334 | Average$582 | FlexibilityNo cancel fee | On-time71% |