HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago de los Caballeros

$151+ Cheap flights from Detroit (DTT) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — STI
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Detroit to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$397
(Cheapflightsfares)

One-way from

$151
(Cheapflightsfares)

Popular in

July

Cheapest in

September

Average price

$507
From Detroit (DTT) to Santiago de los Caballeros
Search Deals
One-way flight from Detroit (DTT) to Santiago de los Caballeros
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($41 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Detroit to Santiago de los Caballeros

Cheapest flights from Detroit to Santiago de los Caballeros
Explore the most affordable flight options available from Detroit to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:11 amDTW - STI
1 stop9h 55mSpirit Airlines
Sat 11/156:18 pmSTI - DTW
1 stop16h 42mSpirit Airlines
Deal found 9/13$397
This SmartFares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/412:16 pmDTW - STI
1 stop12h 08mJetBlue
Wed 10/2212:48 pmSTI - DTW
1 stop11h 11mJetBlue
Deal found 9/14$407
This Priceline deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/282:31 pmDTW - STI
1 stop11h 27mJetBlue
Mon 11/34:41 amSTI - DTW
1 stop9h 55mJetBlue
Deal found 9/13$414
This JetBlue deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/33:12 pmDTW - STI
1 stop7h 15mJetBlue
Mon 11/106:05 amSTI - DTW
1 stop9h 12mJetBlue
Deal found 9/13$415
This JetBlue deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/112:16 pmDTW - STI
1 stop14h 05mJetBlue
Tue 10/79:55 amSTI - DTW
1 stop14h 04mJetBlue
Deal found 9/14$430
This Priceline deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1612:16 pmDTW - STI
1 stop14h 05mJetBlue
Tue 10/215:50 amSTI - DTW
1 stop29h 40mJetBlue
Deal found 9/13$439
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:58 amDTW - STI
1 stop8h 08mSpirit Airlines
Sun 11/236:18 pmSTI - DTW
1 stop7h 07mSpirit Airlines
Deal found 9/13$515
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/225:51 pmDTW - STI
1 stop17h 12mSpirit Airlines
Sat 9/2712:10 pmSTI - DTW
1 stop11h 33mSpirit Airlines
Deal found 9/15$556

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Detroit to Santiago de los Caballeros that are best for you.

Fly from

Detroit

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Sat 10/4

12:16 pm-12:24 am

1 stop12h 08m

Santiago de los Caballeros

Wed 10/22

12:48 pm-11:59 pm

1 stop11h 11m

$407

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Tue 10/28

2:31 pm-1:58 am

1 stop11h 27m

Santiago de los Caballeros

Tue 11/4

7:11 am-1:36 pm

1 stop7h 25m

$414

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Mon 11/3

3:12 pm-2:58 am

1 stop10h 46m

Santiago de los Caballeros

Sun 11/9

4:41 am-2:17 pm

1 stop10h 36m

$415

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Thu 10/16

12:16 pm-2:21 am

1 stop14h 05m

Santiago de los Caballeros

Mon 10/20

3:20 am-11:30 am

1 stop8h 10m

$421

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Wed 10/1

6:00 am-2:13 pm

1 stop8h 13m

Santiago de los Caballeros

Mon 10/6

3:20 am-11:30 am

1 stop8h 10m

$421

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Sat 10/4

5:51 pm-10:38 am

1 stop16h 47m

$151

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Sat 10/4

3:42 pm-10:38 am

2 stops18h 56m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from Detroit to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Santiago de los Caballeros

What is the cheapest month to book a flight from Detroit to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Detroit to Santiago de los Caballeros (average of $347). Flying from Detroit to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to STI?

Find hourly flight availability from Detroit to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

A simple way to save on the total cost of your ticket is to fly from Detroit to Santiago de los Caballeros at noon. If you’re flexible enough to do this you can expect to save up to 60% on your trip compared to booking a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Detroit to Santiago de los Caballeros?

    There are many flights that can get you from Detroit to Santiago de los Caballeros in 12h 08m. Fly via JetBlue to get the fastest option. Detroit and Santiago de los Caballeros are separated by a distance of 1743 mi.

  • What are the cheapest airlines flying from Detroit to Santiago de los Caballeros round-trip?

    Currently priced at $338, Spirit Airlines will fly you from Detroit to Santiago de los Caballeros and back. In addition to Spirit Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from JetBlue and American Airlines - these airlines can fly you to your destination from $442 and $500, respectively. Users have found that Spirit Airlines is 54% cheaper than the other options available to this destination.

  • Can I find deals for flights from Detroit to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Detroit to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santiago de los Caballeros.

  • Can I find deals for business class flights from Detroit to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Detroit to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from Detroit to Santiago de los Caballeros (average of $347). Flying from Detroit to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Punta Cana flights
Detroit to Punta Cana flights
Midway to Punta Cana flights
Grand Rapids to Punta Cana flights
O'Hare Intl to Santo Domingo flights
O'Hare Intl to Puerto Plata flights
Midway to Santo Domingo flights
Detroit to Santo Domingo flights
Detroit to Puerto Plata flights
O'Hare Intl to Santiago de los Caballeros flights
Grand Rapids to Santo Domingo flights
Grand Rapids to Santiago de los Caballeros flights
Flint to Punta Cana flights
Detroit to Santiago de los Caballeros flights
Lansing to Punta Cana flights
Kalamazoo to Punta Cana flights
Grand Rapids to Puerto Plata flights
Midway to Santiago de los Caballeros flights
Lansing to Santo Domingo flights
South Bend to Santiago de los Caballeros flights

Top 3 airlines flying from Detroit to Santiago de los Caballeros

Discover the top 3 airlines that operate flights from Detroit to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$338Average$453FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$442Average$998FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$500Average$656FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.