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Santiago de los Caballeros

$250+ Cheap flights from Buffalo (BUF) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STI
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Buffalo to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$375
(SmartFares)

One-way from

$250
(Delta)

Popular in

September

Cheapest in

March

Average price

$1,251
From Buffalo to Santiago de los Caballeros
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One-way flight from Buffalo to Santiago de los Caballeros
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Highest demand for flights based on searches. 9% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($55 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Buffalo to Santiago de los Caballeros

Cheapest flights from Buffalo to Santiago de los Caballeros
Explore the most affordable flight options available from Buffalo to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This SmartFares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:31 pmBUF - STI
1 stop8h 50mJetBlue
Fri 10/173:20 amSTI - BUF
1 stop11h 39mJetBlue
Deal found 9/15$375
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/163:34 pmBUF - STI
2 stops20h 39mAmerican Airlines
Sat 10/181:14 pmSTI - BUF
2 stops21h 26mAmerican Airlines
Deal found 9/15$449
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:34 pmBUF - STI
2 stops20h 39mAmerican Airlines
Tue 10/141:14 pmSTI - BUF
2 stops21h 28mAmerican Airlines
Deal found 9/14$500
This SmartFares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:10 pmBUF - STI
1 stop16h 44mJetBlue
Tue 10/149:55 amSTI - BUF
1 stop29h 04mJetBlue
Deal found 9/15$507
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:30 amBUF - STI
1 stop8h 42mUnited Airlines
Sat 10/186:00 amSTI - BUF
2 stops10h 53mUnited Airlines
Deal found 9/15$579
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:45 pmBUF - STI
1 stop13h 12mJetBlue
Sun 12/2811:08 pmSTI - BUF
1 stop11h 49mJetBlue
Deal found 9/16$587
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/107:00 amBUF - STI
1 stop27h 28mJetBlue
Tue 10/142:00 pmSTI - BUF
2 stops24h 59mJetBlue
Deal found 9/14$617
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/297:23 pmBUF - STI
1 stop6h 23mUnited Airlines
Tue 10/142:07 pmSTI - BUF
2 stops19h 36mUnited Airlines
Deal found 9/15$662
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:27 amBUF - STI
2 stops12h 06mAmerican Airlines
Sun 12/286:17 pmSTI - BUF
2 stops19h 08mAmerican Airlines
Deal found 9/16$756
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:37 pmBUF - STI
2 stops18h 50mAmerican Airlines
Tue 10/141:14 pmSTI - BUF
2 stops26h 21mAmerican Airlines
Deal found 9/15$766
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:57 pmBUF - STI
1 stop8h 27mDelta
Tue 10/146:00 amSTI - BUF
1 stop9h 10mDelta
Deal found 9/14$768

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Buffalo to Santiago de los Caballeros that are best for you.

Fly from

Buffalo

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Thu 10/16

5:31 pm-2:21 am

1 stop8h 50m

Santiago de los Caballeros

Fri 10/17

3:20 am-2:59 pm

1 stop11h 39m

$375

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Thu 10/16

3:34 pm-12:13 pm

2 stops20h 39m

Santiago de los Caballeros

Sat 10/18

1:14 pm-10:40 am

2 stops21h 26m

$449

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Fri 10/10

3:34 pm-12:13 pm

2 stops20h 39m

Santiago de los Caballeros

Tue 10/14

1:14 pm-10:42 am

2 stops21h 28m

$500

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Thu 10/16

6:30 am-3:12 pm

1 stop8h 42m

Santiago de los Caballeros

Sat 10/18

6:00 am-4:53 pm

2 stops10h 53m

$579

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Sun 12/14

6:45 pm-8:57 am

1 stop13h 12m

Santiago de los Caballeros

Sun 12/28

11:08 pm-9:57 am

1 stop11h 49m

$587

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Fri 10/10

7:00 am-10:28 am

1 stop27h 28m

Santiago de los Caballeros

Tue 10/14

2:00 pm-2:59 pm

2 stops24h 59m

$617

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Mon 9/29

7:23 pm-1:46 am

1 stop6h 23m

Santiago de los Caballeros

Tue 10/14

2:07 pm-9:43 am

2 stops19h 36m

$662

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Mon 9/29

5:37 pm-12:27 pm

2 stops18h 50m

Santiago de los Caballeros

Tue 10/14

1:14 pm-3:35 pm

2 stops26h 21m

$766

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Fri 10/10

3:57 pm-12:24 am

1 stop8h 27m

Santiago de los Caballeros

Tue 10/14

6:00 am-3:10 pm

1 stop9h 10m

$768

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Sun 12/14

11:21 am-1:08 am

1 stop12h 47m

Santiago de los Caballeros

Sat 12/27

3:30 am-3:10 pm

1 stop12h 40m

$823

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 15 results
1
2

Best time to book a flight from Buffalo to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santiago de los Caballeros

What is the cheapest month to book a flight from Buffalo to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Buffalo to Santiago de los Caballeros (average of $347). Flying from Buffalo to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to STI?

Find hourly flight availability from Buffalo to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Buffalo to Santiago de los Caballeros, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 31% versus a flight at noon.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated September 17, 2025.
See what other customers who have flown with United Airlines and JetBlue from Buffalo to Santiago de los Caballeros have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
JetBlue
7.2
Good
2,914 reviews
United Airlines
7.4
Good
8,926 reviews

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santiago de los Caballeros?

    A quick flight from Buffalo to Santiago de los Caballeros can take about 8h 42m. JetBlue provides one of the quickest options available for as low as $579. The distance between Buffalo and Santiago de los Caballeros is about 1692 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Buffalo to Santiago de los Caballeros round-trip?

    Our cheapest airline available from Buffalo to Santiago de los Caballeros is JetBlue. Our recent data shows that you can find tickets from as low as $441 on this airline. An additional option worth looking into is United Airlines, starting at $496. Users have found that JetBlue is 37% cheaper than the other options available to this destination.

  • Can I find deals for flights from Buffalo to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santiago de los Caballeros.

  • Can I find deals for business class flights from Buffalo to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Buffalo to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from Buffalo to Santiago de los Caballeros (average of $347). Flying from Buffalo to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Buffalo to Santiago de los Caballeros

Discover the top 2 airlines that operate flights from Buffalo to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$441Average$659FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$496Average$1,251FlexibilityNo cancel feeOn-time69%

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