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$930+ Cheap flights from Sioux Falls (FSD) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — SCL
Apr 14 — Apr 211
Tue 4/14
Tue 4/21
1 adult, Economy
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Cheap flight deals from Sioux Falls to Santiago

Cheapest flights from Sioux Falls to Santiago
Explore the most affordable flight options available from Sioux Falls to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.

This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
FSD
-
SCL
2 stops23h 50m
American Airlines
Mon 8/178:30 pm
SCL
-
FSD
2 stops21h 05m
American Airlines
Deal found 3/14$930
This KAYAK deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:25 am
FSD
-
SCL
2 stops23h 35m
LATAM Airlines
Tue 8/1811:00 pm
SCL
-
FSD
2 stops24h 09m
LATAM Airlines
Deal found 3/14$980
This KAYAK deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:25 am
FSD
-
SCL
2 stops37h 20m
LATAM Airlines
Sun 8/1612:40 am
SCL
-
FSD
2 stops22h 29m
LATAM Airlines
Deal found 3/14$999
This Expedia deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:25 am
FSD
-
SCL
3 stops31h 00m
LATAM Airlines
Mon 8/178:30 am
SCL
-
FSD
3 stops38h 39m
LATAM Airlines
Deal found 3/14$1,010
This KAYAK deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:25 am
FSD
-
SCL
2 stops23h 35m
LATAM Airlines
Thu 8/2011:00 pm
SCL
-
FSD
2 stops24h 09m
LATAM Airlines
Deal found 3/14$1,012
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/94:09 pm
FSD
-
SCL
2 stops26h 36m
Delta
Sun 8/1611:25 pm
SCL
-
FSD
2 stops20h 41m
Delta
Deal found 3/14$1,030
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:25 am
FSD
-
SCL
1 stop24h 50m
Delta
Thu 8/208:40 pm
SCL
-
FSD
1 stop26h 29m
Delta
Deal found 3/14$1,037
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:50 am
FSD
-
SCL
2 stops23h 00m
American Airlines
Wed 4/88:35 pm
SCL
-
FSD
2 stops27h 36m
American Airlines
Deal found 3/11$1,038
This KAYAK deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:25 am
FSD
-
SCL
2 stops23h 35m
LATAM Airlines
Fri 8/1411:00 pm
SCL
-
FSD
2 stops24h 09m
LATAM Airlines
Deal found 3/14$1,052

Find flight deals from Sioux Falls to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 15, 2026.

Most accurate provider

Ovago
2 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$930
(American Airlines)
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Santiago Arturo Merino Benitez flights.
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From Sioux Falls Joe Foss Field to Santiago Arturo Merino Benitez
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Sioux Falls to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Sun 8/9

5:25 am-7:15 am

1 stop24h 50m

Santiago Arturo Merino Benitez

Tue 8/18

8:40 pm-10:09 pm

1 stop26h 29m

$1,037

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Wed 4/1

6:50 am-7:50 am

2 stops23h 00m

Santiago Arturo Merino Benitez

Wed 4/8

8:35 pm-11:11 pm

2 stops27h 36m

$1,038

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Sat 8/8

5:25 am-7:15 am

1 stop24h 50m

Santiago Arturo Merino Benitez

Mon 8/17

8:40 pm-10:09 pm

1 stop26h 29m

$1,073

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Wed 4/1

5:20 am-7:00 am

2 stops23h 40m

Santiago Arturo Merino Benitez

Wed 4/8

8:30 am-10:12 pm

3 stops38h 42m

$1,075

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Sun 3/29

5:00 am-8:15 am

2 stops25h 15m

Santiago Arturo Merino Benitez

Sun 4/5

11:00 pm-11:04 pm

2 stops25h 04m

$1,336

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Mon 8/10

5:25 am-7:15 am

1 stop24h 50m

Santiago Arturo Merino Benitez

Fri 8/14

8:40 pm-10:09 pm

1 stop26h 29m

$1,371

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Thu 8/13

5:25 am-7:15 am

1 stop24h 50m

Santiago Arturo Merino Benitez

Sun 8/16

8:40 pm-10:09 pm

1 stop26h 29m

$1,371

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Mon 8/10

5:25 am-7:15 am

1 stop24h 50m

Santiago Arturo Merino Benitez

Sat 8/15

8:40 pm-10:09 pm

1 stop26h 29m

$1,371
Quickest round-trip

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Tue 8/11

8:15 am-7:15 am

2 stops22h 00m

Santiago Arturo Merino Benitez

Tue 8/18

8:40 pm-10:09 pm

1 stop26h 29m

$1,375

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/14

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Sioux Falls-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Sioux Falls-Santiago flight deals on Cheapflights vs. Ovago 90-95% of the time. Price accuracy is based on data collected from Sioux Falls-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Sioux Falls-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Sioux Falls to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Sioux Falls to Santiago?

    A quick flight from Sioux Falls to Santiago can take about 23h. Delta provides one of the quickest options available for as low as $1,038. Sioux Falls and Santiago are separated by a distance of 5561 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Sioux Falls to Santiago that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Santiago.

  • Can I find deals for business class flights from Sioux Falls to Santiago?

    Yes. Cheapflights offers flight deals from Sioux Falls to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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