HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$318+ Cheap flights from Santa Cruz de la Sierra (VVI) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SCL
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santa Cruz de la Sierra to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez are usually found in March or December, booked 58 days in advance, depart on a Monday or Wednesday and return on a Monday

Find flight deals from Santa Cruz de la Sierra to Santiago

Cheapest flights from Santa Cruz de la Sierra to Santiago
Explore the most affordable flight options available from Santa Cruz de la Sierra to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:25 amVVI - SCL
1 stop7h 40mMultiple Airlines
Fri 12/2610:15 amSCL - VVI
1 stop15h 55mMultiple Airlines
Deal found 10/29$475
This Booking.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:25 amVVI - SCL
2 stops15h 34mLATAM Airlines
Sat 11/296:32 amSCL - VVI
1 stop4h 56mLATAM Airlines
Deal found 10/29$481
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/72:00 amVVI - SCL
1 stop15h 00mMultiple Airlines
Mon 11/246:30 pmSCL - VVI
1 stop11h 05mMultiple Airlines
Deal found 10/29$492
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:26 amVVI - SCL
Nonstop3h 02mMultiple Airlines
Sat 12/135:06 amSCL - VVI
1 stop16h 49mMultiple Airlines
Deal found 10/29$507
This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:15 amVVI - SCL
Nonstop3h 02mLATAM Airlines
Fri 12/263:00 pmSCL - VVI
1 stop14h 35mLATAM Airlines
Deal found 10/30$508
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/72:00 amVVI - SCL
1 stop15h 00mMultiple Airlines
Fri 11/284:01 amSCL - VVI
1 stop17h 54mMultiple Airlines
Deal found 10/29$512
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/49:50 pmVVI - SCL
2 stops39h 50mMultiple Airlines
Mon 12/16:25 pmSCL - VVI
1 stop7h 45mMultiple Airlines
Deal found 10/29$536
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/172:00 amVVI - SCL
1 stop18h 00mAerolineas Argentinas
Fri 11/2110:15 amSCL - VVI
1 stop15h 55mAerolineas Argentinas
Deal found 10/29$543

Cheap flight deals from Santa Cruz de la Sierra to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$422
(Booking.com)

One-way from

$318
(LATAM Airlines)

Popular in

July

Cheapest in

March

Average price

$489
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-Santiago Arturo Merino Benitez flights.
Search Deals
From Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Santiago that are best for you.

Fly from

Santa Cruz de la Sierra

Fly to

Santiago

Route

Depart

Return

Price

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

8:00 am-12:15 pm

Nonstop3h 15m

Santiago Arturo Merino Benitez

Mon 3/16

3:35 pm-1:10 am

1 stop10h 35m

$422

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

8:00 am-12:15 pm

Nonstop3h 15m

Santiago Arturo Merino Benitez

Mon 3/16

1:10 pm-3:25 pm

Nonstop3h 15m

$435

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Wed 3/11

7:26 am-11:28 am

Nonstop3h 02m

Santiago Arturo Merino Benitez

Mon 3/16

3:35 pm-1:10 am

1 stop10h 35m

$461

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/12

5:25 am-5:55 pm

1 stop11h 30m

Santiago Arturo Merino Benitez

Tue 3/17

6:30 pm-4:35 am

1 stop11h 05m

$466

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 11/14

2:00 am-6:00 pm

1 stop15h 00m

Santiago Arturo Merino Benitez

Mon 11/24

9:05 pm-8:30 am

2 stops12h 25m

$531

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/22

11:15 am-3:17 pm

Nonstop3h 02m

Santiago Arturo Merino Benitez

Sat 11/29

8:50 pm-4:35 am

1 stop8h 45m

$563

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/12

5:25 am-3:30 pm

1 stop9h 05m

Santiago Arturo Merino Benitez

Mon 3/16

1:30 am-5:00 pm

1 stop16h 30m

$592

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/25

5:25 am-5:25 pm

1 stop11h 00m

$318

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sun 12/14

3:40 am-5:30 am

1 stop24h 50m

$668

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Compare providers for flights from Santa Cruz de la Sierra to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Cruz de la Sierra to Santiago in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Cruz de la Sierra-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Santiago

How far ahead should I book a flight from Santa Cruz de la Sierra to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Santa Cruz de la Sierra to Santiago. Price data was last updated on October 24, 2025.

The best time to book flights from Santa Cruz de la Sierra to Santiago is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santiago?

Currently, June is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santiago (average of $262). Flying from Santa Cruz de la Sierra to Santiago in July is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from VVI to SCL?

Find hourly flight availability from Santa Cruz de la Sierra to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 61% on flights from Santa Cruz de la Sierra to Santiago by exploring options for tickets in the afternoon.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Santa Cruz de la Sierra to Santiago, such as Aerolineas Argentinas and LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Aerolineas Argentinas
8.1
Very good
957 reviews

Overall

8.1

Entertainment

5.8

Boarding

8.0

Food

6.5

Crew

8.3

Comfort

7.6

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
Aerolineas Argentinas
8.1
Very good
957 reviews
Aerolineas Argentinas
8.1
Very good
957 reviews

Overall

8.1

Entertainment

5.8

Boarding

8.0

Food

6.5

Crew

8.3

Comfort

7.6

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
LATAM Airlines
7.5
Good
1,872 reviews
Aerolineas Argentinas
8.1
Very good
957 reviews

Overall

8.1

Entertainment

5.8

Boarding

8.0

Food

6.5

Crew

8.3

Comfort

7.6

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Santiago?

    BoA can get you from Santa Cruz de la Sierra to Santiago in just under 3h 15m. Your travel time will be generally consistent. There are 1186 mi between Santa Cruz de la Sierra and Santiago. Most flights are nonstop.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to Santiago round-trip?

    According to our current data, LATAM Airlines ($290), and Aerolineas Argentinas ($359) offers the cheapest pricing from Santa Cruz de la Sierra to Santiago. These flights start at 42% lower than the current average price 3 months from now.

  • What are the cheapest flights from Santa Cruz de la Sierra to Santiago?

    While on average a flight from Santa Cruz de la Sierra to Santiago is generally $407, our data shows the cheapest flight currently is $220. When looking at the most popular route, (Santa Cruz de la Sierra Viru Viru Intl - Santiago Arturo Merino Benitez), you can expect to pay $422 for that flight.

  • Can I find deals for flights from Santa Cruz de la Sierra to Santiago that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Santiago.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Santiago?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santiago?

    Currently, June is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santiago (average of $262). Flying from Santa Cruz de la Sierra to Santiago in July is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Cruz de la Sierra to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
La Paz to Santiago flights

Top 2 airlines flying from Santa Cruz de la Sierra to Santiago

Discover the top 2 airlines that operate flights from Santa Cruz de la Sierra to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$290Average$556FlexibilityNo cancel feeOn-time81%
Aerolineas ArgentinasCheapest$359Average$417FlexibilityNo cancel feeOn-time59%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.