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$281+ Cheap flights from Santa Cruz de la Sierra (VVI) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SCL
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheapflights Tip: The best prices from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez are usually found in September or February, booked 53 days in advance, depart on a Wednesday or Monday and return on a Monday

Cheap flight deals from Santa Cruz de la Sierra to Santiago

Cheapest flights from Santa Cruz de la Sierra to Santiago
Explore the most affordable flight options available from Santa Cruz de la Sierra to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This FlightHub deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/152:20 am
VVI
-
SCL
1 stop17h 15m
Aerolineas Argentinas
Thu 6/188:50 pm
SCL
-
VVI
1 stop28h 20m
Aerolineas Argentinas
Deal found 3/19$476
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:00 am
VVI
-
SCL
Nonstop3h 15m
Multiple Airlines
Sat 7/185:32 am
SCL
-
VVI
1 stop4h 57m
Multiple Airlines
Deal found 3/20$484
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/272:00 am
VVI
-
SCL
1 stop16h 05m
Multiple Airlines
Sat 4/49:06 am
SCL
-
VVI
1 stop12h 49m
Multiple Airlines
Deal found 3/21$508
This CheapOair deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:25 am
VVI
-
SCL
1 stop15h 30m
Multiple Airlines
Fri 5/299:15 am
SCL
-
VVI
1 stop15h 55m
Multiple Airlines
Deal found 3/19$516
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:15 am
VVI
-
SCL
Nonstop3h 09m
Multiple Airlines
Sun 5/108:50 pm
SCL
-
VVI
1 stop28h 20m
Multiple Airlines
Deal found 3/23$525
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:25 am
VVI
-
SCL
1 stop12h 00m
Multiple Airlines
Sat 6/612:10 pm
SCL
-
VVI
Nonstop3h 15m
Multiple Airlines
Deal found 3/20$537
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:00 am
VVI
-
SCL
Nonstop3h 15m
Multiple Airlines
Sun 7/121:30 pm
SCL
-
VVI
1 stop15h 05m
Multiple Airlines
Deal found 3/20$539
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:25 am
VVI
-
SCL
1 stop16h 30m
LATAM Airlines
Fri 5/297:55 pm
SCL
-
VVI
1 stop8h 40m
LATAM Airlines
Deal found 3/22$546

Find flight deals from Santa Cruz de la Sierra to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$476
(FlightHub)

One-way from

$281
(Mytrip)

Popular in

July

Cheapest in

September

Average price

$557
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-Santiago Arturo Merino Benitez flights.
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From Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez
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One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Thu 5/7

5:25 am-5:25 pm

1 stop12h 00m

Santiago Arturo Merino Benitez

Sun 5/10

8:50 pm-1:10 am

1 stop28h 20m

$525

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 5/15

5:25 am-4:45 pm

1 stop11h 20m

Santiago Arturo Merino Benitez

Fri 5/29

9:15 am-1:10 am

1 stop15h 55m

$530
Quickest round-trip

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/23

11:15 am-2:24 pm

Nonstop3h 09m

Santiago Arturo Merino Benitez

Sat 6/6

12:10 pm-3:25 pm

Nonstop3h 15m

$537

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/23

5:25 am-5:25 pm

1 stop12h 00m

Santiago Arturo Merino Benitez

Sat 6/6

5:32 am-10:29 am

1 stop4h 57m

$560

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Mon 5/4

5:25 am-2:05 pm

1 stop8h 40m

Santiago Arturo Merino Benitez

Wed 5/27

6:45 pm-4:35 am

1 stop9h 50m

$569
Cheapest one-way

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/30

2:00 am-7:20 pm

1 stop16h 20m

$281

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/10

2:20 am-7:45 am

1 stop29h 25m

$284

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/23

5:25 am-4:35 pm

1 stop11h 10m

$334

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/24

11:10 am-4:11 am

3 stops17h 01m

$366

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sat 4/4

4:25 pm-11:06 am

1 stop17h 41m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/21

Showing 1-10 of 13 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Santiago

How far ahead should I book a flight from Santa Cruz de la Sierra to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Santa Cruz de la Sierra to Santiago. Price data was last updated on March 13, 2026.

The best time to book flights from Santa Cruz de la Sierra to Santiago is 53 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santiago?

Currently, February is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santiago (average of $243). Flying from Santa Cruz de la Sierra to Santiago in July is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from VVI to SCL?

Find hourly flight availability from Santa Cruz de la Sierra to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 23, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santa Cruz de la Sierra to Santiago as you normally would.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 23, 2026.
Read through reviews of airlines operating flights from Santa Cruz de la Sierra to Santiago, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,915 reviews

Overall

7.4

Boarding

7.5

Food

6.7

Comfort

7.3

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Victoria E,Mar 2026

SCL - JFK

I was charged $130 to check my baggage from Santiago Chile to New York. It was only one baggage checked and it wasn’t fully the standard size. And then to get hit with $130 was to me not favorable to the airlines. Because on most international travel, they allow one bag to be checked in. So in the future, I would have to think twice about booking Latam again other than that it’s a very good airline.
LATAM Airlines
7.4
Good
1,915 reviews
LATAM Airlines
7.4
Good
1,915 reviews

Overall

7.4

Boarding

7.5

Food

6.7

Comfort

7.3

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Victoria E,Mar 2026

SCL - JFK

I was charged $130 to check my baggage from Santiago Chile to New York. It was only one baggage checked and it wasn’t fully the standard size. And then to get hit with $130 was to me not favorable to the airlines. Because on most international travel, they allow one bag to be checked in. So in the future, I would have to think twice about booking Latam again other than that it’s a very good airline.

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santa Cruz de la Sierra to Santiago flight route?

    The Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What is the cheapest airline to fly from Santa Cruz de la Sierra to Santiago round-trip?

    According to our current data, LATAM Airlines ($467), offers the cheapest pricing from Santa Cruz de la Sierra to Santiago. This flight start at 11% lower than the current average price 3 months from now.

  • What are the cheapest flights from Santa Cruz de la Sierra to Santiago?

    While on average a flight from Santa Cruz de la Sierra to Santiago is generally $544, our data shows the cheapest flight currently is $247. When looking at the most popular route, (Santa Cruz de la Sierra Viru Viru Intl - Santiago Arturo Merino Benitez), you can expect to pay $526 for that flight.

  • Can I find deals for flights from Santa Cruz de la Sierra to Santiago that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Santiago.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Santiago?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santiago?

    Currently, February is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santiago (average of $243). Flying from Santa Cruz de la Sierra to Santiago in July is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santa Cruz de la Sierra to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
La Paz to Santiago flights

Top airline flying from Santa Cruz de la Sierra to Santiago

Discover the top airline that operate flights from Santa Cruz de la Sierra to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$467Average$589FlexibilityNo cancel feeOn-time81%

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