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$274+ Cheap flights from Santa Cruz de la Sierra (VVI) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SCL
Aug 6 — Aug 131
Wed 8/6
Wed 8/13
1 adult, Economy
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Cheapflights Tip: The best prices from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez are usually found in November or December, booked 58 days in advance, depart on a Monday or Tuesday and return on a Monday

Cheap flight deals from Santa Cruz de la Sierra to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 1, 2025.

Round-trip from

$447
(Mytrip)

One-way from

$274
(FlightHub)

Popular in

July

Cheapest in

November

Average price

$469
From Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez
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One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 5% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Santa Cruz de la Sierra to Santiago

Cheapest flights from Santa Cruz de la Sierra to Santiago
Explore the most affordable flight options available from Santa Cruz de la Sierra to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2025.

This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:25 amVVI - SCL
1 stop11h 30mLATAM Airlines
Sat 11/296:32 amSCL - VVI
1 stop4h 56mLATAM Airlines
Deal found 7/30$459
This KAYAK deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:00 amVVI - SCL
1 stop18h 15mAerolineas Argentinas
Fri 12/263:35 pmSCL - VVI
1 stop10h 35mAerolineas Argentinas
Deal found 7/30$480
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/309:05 amVVI - SCL
2 stops23h 00mMultiple Airlines
Sun 9/72:35 pmSCL - VVI
1 stop15h 00mMultiple Airlines
Deal found 7/30$515

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Santiago that are best for you.

Fly from

Santa Cruz de la Sierra

Fly to

Santiago

Route

Depart

Return

Price

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/22

5:25 am-5:20 pm

1 stop10h 55m

Santiago Arturo Merino Benitez

Sat 11/29

6:32 am-10:28 am

1 stop4h 56m

$459

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 12/19

2:00 am-9:15 pm

1 stop18h 15m

Santiago Arturo Merino Benitez

Fri 12/26

3:35 pm-1:10 am

1 stop10h 35m

$480

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/30

9:05 am-8:05 am

2 stops23h 00m

Santiago Arturo Merino Benitez

Sun 9/7

2:35 pm-4:35 am

1 stop15h 00m

$515

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/6

5:25 am-9:55 pm

1 stop15h 30m

$274

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 9/19

2:00 am-9:45 am

1 stop6h 45m

$349

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 9/19

10:00 am-11:16 pm

2 stops12h 16m

$363

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Wed 11/5

3:40 am-5:35 am

1 stop24h 55m

$607

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Santa Cruz de la Sierra to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Santiago

How far ahead should I book a flight from Santa Cruz de la Sierra to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Santa Cruz de la Sierra to Santiago. Price data was last updated on July 25, 2025.

The best time to book flights from Santa Cruz de la Sierra to Santiago is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santiago?

Currently, April is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santiago (average of $752). Flying from Santa Cruz de la Sierra to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from VVI to SCL?

Find hourly flight availability from Santa Cruz de la Sierra to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 1, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 36% on flights from Santa Cruz de la Sierra to Santiago by exploring options for tickets at noon.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated August 1, 2025.
Read through reviews of airlines operating flights from Santa Cruz de la Sierra to Santiago, such as Aerolineas Argentinas, LATAM Airlines, and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Aerolineas Argentinas
8.1
Very good
899 reviews

Boarding

8.0

Overall

8.1

Comfort

7.5

Entertainment

5.7

Food

6.4

Crew

8.3

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
Aerolineas Argentinas
8.1
Very good
899 reviews
Aerolineas Argentinas
8.1
Very good
899 reviews

Boarding

8.0

Overall

8.1

Comfort

7.5

Entertainment

5.7

Food

6.4

Crew

8.3

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
LATAM Airlines
7.5
Good
1,822 reviews
Aerolineas Argentinas
8.1
Very good
899 reviews

Boarding

8.0

Overall

8.1

Comfort

7.5

Entertainment

5.7

Food

6.4

Crew

8.3

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
Avianca
6.7
Okay
2,388 reviews
Aerolineas Argentinas
8.1
Very good
899 reviews

Boarding

8.0

Overall

8.1

Comfort

7.5

Entertainment

5.7

Food

6.4

Crew

8.3

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santa Cruz de la Sierra to Santiago flight route?

    The Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to Santiago round-trip?

    According to our current data, Aerolineas Argentinas ($447), and LATAM Airlines ($459) offers the cheapest pricing from Santa Cruz de la Sierra to Santiago. These flights start at 9% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Santa Cruz de la Sierra to Santiago one-way?

    One-way options have recently been found by users for as low as $274 on LATAM Airlines. Other airlines that offer cheap prices include Aerolineas Argentinas from $349 and Avianca from $607 one-way.

  • What are the cheapest flights from Santa Cruz de la Sierra to Santiago?

    While on average a flight from Santa Cruz de la Sierra to Santiago is generally $626, our data shows the cheapest flight currently is $226. When looking at the most popular route, (Santa Cruz de la Sierra Viru Viru Intl - Santiago Arturo Merino Benitez), you can expect to pay $468 for that flight.

  • Can I find deals for flights from Santa Cruz de la Sierra to Santiago that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Santiago.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Santiago?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santiago (average of $752). Flying from Santa Cruz de la Sierra to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santa Cruz de la Sierra to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
La Paz to Santiago flights

Top 2 airlines flying from Santa Cruz de la Sierra to Santiago

Discover the top 2 airlines that operate flights from Santa Cruz de la Sierra to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$290Average$544FlexibilityNo cancel feeOn-time81%
Aerolineas ArgentinasCheapest$359Average$421FlexibilityNo cancel feeOn-time59%

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