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$374+ Cheap flights from Santa Cruz de la Sierra (VVI) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SCL
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez are usually found in March or September, booked 58 days in advance, depart on a Tuesday or Monday and return on a Monday

Cheap flight deals from Santa Cruz de la Sierra to Santiago

Cheapest flights from Santa Cruz de la Sierra to Santiago
Explore the most affordable flight options available from Santa Cruz de la Sierra to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Mytrip deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:00 amVVI - SCL
1 stop10h 59mMultiple Airlines
Fri 1/166:30 pmSCL - VVI
1 stop11h 05mMultiple Airlines
Deal found 12/17$676
This Gotogate deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:25 amVVI - SCL
1 stop7h 32mLATAM Airlines
Fri 1/166:30 pmSCL - VVI
1 stop11h 05mLATAM Airlines
Deal found 12/17$710
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:15 amVVI - SCL
Nonstop3h 02mMultiple Airlines
Fri 12/263:35 pmSCL - VVI
1 stop10h 35mMultiple Airlines
Deal found 12/16$754
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:00 amVVI - SCL
1 stop15h 00mAerolineas Argentinas
Fri 12/263:35 pmSCL - VVI
1 stop10h 35mAerolineas Argentinas
Deal found 12/16$785
This CheapOair deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:15 amVVI - SCL
Nonstop3h 02mLATAM Airlines
Fri 12/266:30 pmSCL - VVI
1 stop11h 05mLATAM Airlines
Deal found 12/17$811
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:00 amVVI - SCL
1 stop15h 00mMultiple Airlines
Fri 1/28:50 pmSCL - VVI
1 stop8h 45mMultiple Airlines
Deal found 12/16$877
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:15 amVVI - SCL
Nonstop3h 02mLATAM Airlines
Fri 1/28:50 pmSCL - VVI
1 stop8h 45mLATAM Airlines
Deal found 12/16$905

Find flight deals from Santa Cruz de la Sierra to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$474
(CheapOair)

One-way from

$374
(FlightHub)

Popular in

January

Cheapest in

March

Average price

$500
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-Santiago Arturo Merino Benitez flights.
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From Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Santiago that are best for you.

Fly from

Santa Cruz de la Sierra

Fly to

Santiago

Route

Depart

Return

Price

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/10

5:25 am-9:55 pm

1 stop16h 30m

Santiago Arturo Merino Benitez

Sat 4/18

12:10 pm-3:25 pm

Nonstop3h 15m

$474

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 5/15

5:25 am-4:30 pm

1 stop11h 05m

Santiago Arturo Merino Benitez

Fri 5/29

3:55 pm-1:10 am

1 stop9h 15m

$475

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/10

5:25 am-4:30 pm

1 stop11h 05m

Santiago Arturo Merino Benitez

Sat 4/18

6:45 pm-4:35 am

1 stop9h 50m

$490

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/17

11:15 am-3:17 pm

Nonstop3h 02m

Santiago Arturo Merino Benitez

Sun 1/25

6:30 pm-4:35 am

1 stop11h 05m

$494

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Wed 2/18

8:00 am-4:36 pm

1 stop7h 36m

Santiago Arturo Merino Benitez

Sat 2/28

1:10 pm-3:25 pm

Nonstop3h 15m

$495

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 5/8

5:25 am-2:05 pm

1 stop8h 40m

Santiago Arturo Merino Benitez

Tue 5/12

4:50 pm-4:35 am

1 stop11h 45m

$495

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/24

4:25 pm-11:00 am

1 stop17h 35m

Santiago Arturo Merino Benitez

Sat 2/14

6:32 am-10:28 am

1 stop4h 56m

$501

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Wed 3/11

7:26 am-11:28 am

Nonstop3h 02m

Santiago Arturo Merino Benitez

Mon 3/16

8:25 am-4:35 am

2 stops21h 10m

$510

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Tue 2/10

5:25 am-5:25 pm

1 stop11h 00m

$374

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Tue 2/10

12:00 pm-9:00 pm

2 stops32h 00m

$416

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Compare providers for flights from Santa Cruz de la Sierra to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Cruz de la Sierra to Santiago in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Cruz de la Sierra-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Santiago

How far ahead should I book a flight from Santa Cruz de la Sierra to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Santa Cruz de la Sierra to Santiago. Price data was last updated on December 12, 2025.

The best time to book flights from Santa Cruz de la Sierra to Santiago is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santiago?

Currently, June is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santiago (average of $260). Flying from Santa Cruz de la Sierra to Santiago in July is currently the most expensive (average of $464). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from VVI to SCL?

Find hourly flight availability from Santa Cruz de la Sierra to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santa Cruz de la Sierra to Santiago as you normally would.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from Santa Cruz de la Sierra to Santiago, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,893 reviews

Entertainment

7.0

Boarding

7.6

Overall

7.5

Food

6.7

Crew

8.0

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
LATAM Airlines
7.5
Good
1,893 reviews
LATAM Airlines
7.5
Good
1,893 reviews

Entertainment

7.0

Boarding

7.6

Overall

7.5

Food

6.7

Crew

8.0

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Santiago?

    LATAM Airlines can get you from Santa Cruz de la Sierra to Santiago in just under 11h 05m. Your travel time can differ by up to . There are 1186 mi between Santa Cruz de la Sierra and Santiago.

  • What is the cheapest airline to fly from Santa Cruz de la Sierra to Santiago round-trip?

    According to our current data, LATAM Airlines ($290), offers the cheapest pricing from Santa Cruz de la Sierra to Santiago. This flight start at 44% lower than the current average price 3 months from now.

  • What are the cheapest flights from Santa Cruz de la Sierra to Santiago?

    While on average a flight from Santa Cruz de la Sierra to Santiago is generally $660, our data shows the cheapest flight currently is $522. When looking at the most popular route, (Santa Cruz de la Sierra Viru Viru Intl - Santiago Arturo Merino Benitez), you can expect to pay $460 for that flight.

  • Can I find deals for flights from Santa Cruz de la Sierra to Santiago that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Santiago.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Santiago?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santiago?

    Currently, June is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santiago (average of $260). Flying from Santa Cruz de la Sierra to Santiago in July is currently the most expensive (average of $464). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santa Cruz de la Sierra to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
La Paz to Santiago flights

Top airline flying from Santa Cruz de la Sierra to Santiago

Discover the top airline that operate flights from Santa Cruz de la Sierra to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$290Average$531FlexibilityNo cancel feeOn-time81%

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