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$308+ Cheap flights from San Antonio (SAT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from San Antonio to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2025.

Round-trip from

$735
(FlightHub)

One-way from

$308
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$893
From San Antonio to Santiago Arturo Merino Benitez
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One-way flight from San Antonio to Santiago Arturo Merino Benitez
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High demand for flights, 7% potential price rise
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Cheapest flight prices on average. 2% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from San Antonio to Santiago

Cheapest flights from San Antonio to Santiago
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/41:19 pmSAT - SCL
2 stops16h 26mLATAM Airlines
Tue 9/165:55 pmSCL - SAT
2 stops19h 24mLATAM Airlines
Deal found 7/28$735
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2112:05 pmSAT - SCL
2 stops17h 40mDelta
Wed 9/311:05 pmSCL - SAT
2 stops16h 21mDelta
Deal found 7/29$740
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/215:20 amSAT - SCL
1 stop24h 35mAmerican Airlines
Wed 9/39:55 pmSCL - SAT
1 stop27h 00mAmerican Airlines
Deal found 7/29$749
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/114:30 pmSAT - SCL
2 stops33h 05mMultiple Airlines
Thu 8/149:45 amSCL - SAT
1 stop24h 45mMultiple Airlines
Deal found 7/30$788

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.

Fly from

San Antonio

Fly to

Santiago

Route

Depart

Return

Price

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 9/4

1:19 pm-6:45 am

2 stops16h 26m

Santiago Arturo Merino Benitez

Tue 9/16

5:55 pm-11:19 am

2 stops19h 24m

$735

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 8/21

12:05 pm-6:45 am

2 stops17h 40m

Santiago Arturo Merino Benitez

Wed 9/3

11:05 pm-2:26 pm

2 stops16h 21m

$740

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 8/21

5:20 am-6:55 am

1 stop24h 35m

Santiago Arturo Merino Benitez

Wed 9/3

9:55 pm-11:55 pm

1 stop27h 00m

$749

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 8/11

4:30 pm-2:35 am

2 stops33h 05m

Santiago Arturo Merino Benitez

Thu 8/14

9:45 am-9:30 am

1 stop24h 45m

$788

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Fri 9/12

2:54 pm-2:25 pm

2 stops45h 31m

$308

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Wed 1/14

4:25 pm-2:05 pm

2 stops18h 40m

$511

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from San Antonio to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Santiago

What is the cheapest month to book a flight from San Antonio to Santiago?

Currently, April is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $752). Flying from San Antonio to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from San Antonio to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 30, 2025.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as Delta, LATAM Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,822 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from San Antonio to Santiago round-trip?

    LATAM Airlines, at $735, was found to be the cheapest airline from San Antonio to Santiago.Alternate airlines to your destination round-trip include Delta and American Airlines. LATAM Airlines is priced at 27% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Santiago that include hotel bookings?

    Yes. In addition to deals on San Antonio to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Santiago.

  • Can I find deals for business class flights from San Antonio to Santiago?

    Yes. Cheapflights offers flight deals from San Antonio to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Santiago?

    Currently, April is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $752). Flying from San Antonio to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from San Antonio to Santiago

Discover the top 4 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$682Average$948FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$747Average$927FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$753Average$1,116FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$753Average$1,098FlexibilityNo cancel feeOn-time81%

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