$564+ Cheap flights from San Antonio (SAT) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
abr. 9 — abr. 161
Round-trip
1 adult, Economy
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Find cheap flights from San Antonio to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Santiago
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Cheapest flights from San Antonio to SantiagoExplore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on març 10, 2026.
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on març 10, 2026.
This FlightHub deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 10/232:10 pm
SAT
- SCL
2 stops14h 45m
LATAM Airlines
dc. 11/412:40 am
SCL
- SAT
2 stops19h 38m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$855
This FlightHub deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 4/201:55 pm
SAT
- SCL
2 stops16h 00m
LATAM Airlines
dl. 4/275:40 am
SCL
- SAT
2 stops20h 06m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$860
This LATAM Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 4/2110:42 am
SAT
- SCL
2 stops18h 03m
LATAM Airlines
dt. 4/284:10 am
SCL
- SAT
2 stops21h 36m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$862
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 10/2312:10 pm
SAT
- SCL
1 stop16h 40m
Delta
dj. 11/511:10 pm
SCL
- SAT
1 stop24h 12m
Delta
Deal found 3/7![Delta logo]()
$865
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 4/2012:26 pm
SAT
- SCL
1 stop17h 49m
Delta
dl. 4/278:40 pm
SCL
- SAT
1 stop22h 29m
Delta
Deal found 3/6![Delta logo]()
$870
This Mytrip deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 5/36:00 am
SAT
- SCL
2 stops21h 16m
Multiple Airlines
dt. 5/1212:30 am
SCL
- SAT
2 stops24h 29m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$893
This Gurufare deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 9/192:10 pm
SAT
- SCL
2 stops25h 15m
LATAM Airlines
ds. 9/267:45 am
SCL
- SAT
2 stops18h 30m
LATAM Airlines
Deal found 3/6![LATAM Airlines logo]()
$905
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 11/25:55 pm
SAT
- SCL
1 stop11h 55m
United Airlines
dj. 11/510:45 pm
SCL
- SAT
1 stop15h 03m
United Airlines
Deal found 3/5![United Airlines logo]()
$915
Best flights from San Antonio to SantiagoDiscover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated març 10, 2026.
Discover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated març 10, 2026.
This FlightHub deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 4/201:55 pm
SAT
- SCL
2 stops16h 00m
LATAM Airlines
dl. 4/275:40 am
SCL
- SAT
2 stops20h 06m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$860
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 4/2012:26 pm
SAT
- SCL
1 stop17h 49m
Delta
dl. 4/278:40 pm
SCL
- SAT
1 stop22h 29m
Delta
Deal found 3/6![Delta logo]()
$870
This Mytrip deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 5/31:06 pm
SAT
- SCL
3 stops24h 09m
Multiple Airlines
dt. 5/123:35 am
SCL
- SAT
3 stops34h 42m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$950
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 4/217:40 am
SAT
- SCL
2 stops14h 03m
United Airlines
dl. 4/2712:46 am
SCL
- SAT
2 stops16h 00m
United Airlines
Deal found 3/7![United Airlines logo]()
$1,033
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 3/255:00 am
SAT
- SCL
1 stop24h 00m
American Airlines
dc. 6/38:35 pm
SCL
- SAT
2 stops16h 21m
American Airlines
Deal found 3/9![American Airlines logo]()
$1,118
This LATAM Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 4/2110:42 am
SAT
- SCL
2 stops18h 03m
LATAM Airlines
dt. 4/284:10 am
SCL
- SAT
2 stops21h 36m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$862
This KAYAK deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 5/33:33 pm
SAT
- SCL
1 stop37h 02m
LATAM Airlines
dc. 5/138:40 pm
SCL
- SAT
1 stop15h 23m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$931
This FlightHub deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 4/174:20 pm
SAT
- SCL
3 stops20h 05m
LATAM Airlines
ds. 4/2511:05 pm
SCL
- SAT
2 stops22h 25m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$955
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 4/244:17 pm
SAT
- SCL
3 stops26h 06m
United Airlines
dv. 5/14:09 am
SCL
- SAT
2 stops19h 50m
United Airlines
Deal found 3/10![United Airlines logo]()
$1,163
Last-minute flights from San Antonio to SantiagoDiscover last-minute flight deals from San Antonio to Santiago. Data last updated març 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Santiago. Data last updated març 10, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 3/2510:22 am
SAT
- SCL
2 stops22h 17m
Multiple Airlines
dc. 6/33:20 pm
SCL
- SAT
3 stops33h 31m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$953
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 3/258:05 am
SAT
- SCL
1 stop20h 55m
American Airlines
dc. 6/38:35 pm
SCL
- SAT
1 stop22h 10m
American Airlines
Deal found 3/9![American Airlines logo]()
$1,114
This FlightHub deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 4/1710:42 am
SAT
- SCL
2 stops17h 08m
LATAM Airlines
ds. 4/2511:05 pm
SCL
- SAT
2 stops22h 25m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$950
This FlightHub deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 4/201:55 pm
SAT
- SCL
2 stops16h 00m
LATAM Airlines
dl. 4/275:40 am
SCL
- SAT
2 stops20h 06m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$860
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 4/2012:26 pm
SAT
- SCL
1 stop17h 49m
Delta
dl. 4/278:40 pm
SCL
- SAT
1 stop22h 29m
Delta
Deal found 3/6![Delta logo]()
$870
This LATAM Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 4/2110:42 am
SAT
- SCL
2 stops18h 03m
LATAM Airlines
dt. 4/284:10 am
SCL
- SAT
2 stops21h 36m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$862
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 4/217:40 am
SAT
- SCL
2 stops14h 03m
United Airlines
dl. 4/2712:46 am
SCL
- SAT
2 stops16h 00m
United Airlines
Deal found 3/7![United Airlines logo]()
$1,033
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 4/244:17 pm
SAT
- SCL
3 stops26h 06m
United Airlines
dv. 5/14:09 am
SCL
- SAT
2 stops19h 50m
United Airlines
Deal found 3/10![United Airlines logo]()
$1,163
One-way flights from San Antonio to SantiagoSearch for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated març 10, 2026.
Search for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated març 10, 2026.
This Atrapalo deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Atrapalo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 5/245:00 pm
SAT
- SCL
1 stop13h 15m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$564
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 6/812:15 pm
SAT
- SCL
2 stops17h 40m
Delta
Deal found 3/10![Delta logo]()
$578
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 6/76:20 pm
SAT
- SCL
2 stops35h 35m
Delta
Deal found 3/10![Delta logo]()
$584
This eDestinos deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 5/248:41 pm
SAT
- SCL
2 stops29h 19m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$604
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 6/1212:50 pm
SAT
- SCL
2 stops17h 05m
Delta
Deal found 3/10![Delta logo]()
$628
This deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 3/162:20 pm
SAT
- SCL
1 stop15h 30m
United Airlines
Deal found 3/8![United Airlines logo]()
$643
Find flight deals from San Antonio to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated març 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $849 (Kiwi.com) |
One-way from | $564 (Atrapalo) |
Popular in | June |
Cheapest in | January |
Average price | $875 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated març 10, 2026.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
dl. 4/20
1:55 pm-6:55 am
2 stops16h 00m
Santiago Arturo Merino Benitez
dl. 4/27
5:40 am-12:46 am
2 stops20h 06m
$860
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
dt. 4/21
10:42 am-5:45 am
2 stops18h 03m
Santiago Arturo Merino Benitez
dt. 4/28
4:10 am-12:46 am
2 stops21h 36m
$862
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
dl. 4/20
12:26 pm-7:15 am
1 stop17h 49m
Santiago Arturo Merino Benitez
dl. 4/27
8:40 pm-6:09 pm
1 stop22h 29m
$870
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
dg. 5/3
3:33 pm-5:35 am
1 stop37h 02m
Santiago Arturo Merino Benitez
dc. 5/13
8:40 pm-11:03 am
1 stop15h 23m
$931
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
dg. 5/3
1:06 pm-2:15 pm
3 stops24h 09m
Santiago Arturo Merino Benitez
dt. 5/12
3:35 am-1:17 pm
3 stops34h 42m
$950
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
dv. 4/17
4:20 pm-1:25 pm
3 stops20h 05m
Santiago Arturo Merino Benitez
ds. 4/25
11:05 pm-8:30 pm
2 stops22h 25m
$955
Quickest round-trip
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
dt. 4/21
7:40 am-10:43 pm
2 stops14h 03m
Santiago Arturo Merino Benitez
dl. 4/27
12:46 am-3:46 pm
2 stops16h 00m
$1,033
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
dc. 3/25
5:00 am-7:00 am
1 stop24h 00m
Santiago Arturo Merino Benitez
dc. 6/3
8:35 pm-11:56 am
2 stops16h 21m
$1,118
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
dv. 4/24
4:17 pm-7:23 pm
3 stops26h 06m
Santiago Arturo Merino Benitez
dv. 5/1
4:09 am-10:59 pm
2 stops19h 50m
$1,163
Cheapest one-way
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
dc. 6/10
6:30 am-5:35 am
1 stop22h 05m
$578
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
SAT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Santiago
What is the cheapest month to book a flight from San Antonio to Santiago?
Currently, September is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $260). Flying from San Antonio to Santiago in December is currently the most expensive (average of $703). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Antonio to Santiago?
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated març 10, 2026.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Other flights from San Antonio
Popular flights
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Alternative routes for San Antonio to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Antonio to Santiago by cabin class
Find flights from San Antonio to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Antonio and Santiago flights
Browse other San Antonio and Santiago flight options. Last updated on març 10, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on març 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on març 10, 2026.
Top 4 airlines flying from San Antonio to Santiago
Discover the top 4 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated març 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$566 | Average$859 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$753 | Average$1,116 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$778 | Average$1,273 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$796 | Average$1,090 | FlexibilityNo cancel fee | On-time81% |