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$335+ Cheap flights from San Antonio (SAT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from San Antonio to Santiago

Cheapest flights from San Antonio to Santiago
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:00 amSAT - SCL
1 stop21h 45mAmerican Airlines
Fri 1/2310:30 pmSCL - SAT
1 stop20h 15mAmerican Airlines
Deal found 12/10$1,074
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:55 amSAT - SCL
1 stop19h 55mUnited Airlines
Fri 1/2310:45 pmSCL - SAT
2 stops21h 08mUnited Airlines
Deal found 12/10$1,079
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:59 pmSAT - SCL
1 stop11h 51mUnited Airlines
Sat 1/310:45 pmSCL - SAT
1 stop13h 05mUnited Airlines
Deal found 12/10$1,769
This KAYAK deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:10 amSAT - SCL
2 stops30h 10mLATAM Airlines
Sat 1/34:35 pmSCL - SAT
2 stops35h 03mLATAM Airlines
Deal found 12/11$2,141

Find flight deals from San Antonio to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$714
(American Airlines)

One-way from

$335
(Mytrip)

Popular in

June

Cheapest in

September

Average price

$954
Provider with most accurate pricing for San Antonio-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for San Antonio-Santiago Arturo Merino Benitez flights.
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From San Antonio to Santiago Arturo Merino Benitez
Search Deals
One-way flight from San Antonio to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($109 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.

Fly from

San Antonio

Fly to

Santiago

Route

Depart

Return

Price

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

7:00 am-8:15 am

1 stop22h 15m

Santiago Arturo Merino Benitez

Mon 2/2

10:30 pm-7:26 pm

1 stop23h 56m

$714

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

10:45 am-5:25 pm

2 stops27h 40m

Santiago Arturo Merino Benitez

Sun 2/1

4:35 am-12:38 am

2 stops23h 03m

$716

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

1:40 pm-7:40 am

1 stop15h 00m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-12:38 am

2 stops29h 23m

$744

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

8:00 am-7:40 am

1 stop20h 40m

Santiago Arturo Merino Benitez

Sun 2/1

11:10 pm-5:22 pm

1 stop21h 12m

$754

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

5:10 am-9:00 am

1 stop24h 50m

Santiago Arturo Merino Benitez

Sun 2/1

10:35 pm-4:30 pm

1 stop20h 55m

$754

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

1:40 pm-7:40 am

1 stop15h 00m

Santiago Arturo Merino Benitez

Sun 2/1

11:10 pm-5:22 pm

1 stop21h 12m

$754

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sat 3/14

10:46 am-6:35 am

2 stops17h 49m

Santiago Arturo Merino Benitez

Sun 3/29

10:10 pm-12:32 am

2 stops28h 22m

$754

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

8:16 am-8:15 am

1 stop20h 59m

Santiago Arturo Merino Benitez

Sun 2/1

10:35 pm-4:30 pm

1 stop20h 55m

$754

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 1/25

10:35 am-6:40 am

2 stops17h 05m

$335

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 3/15

1:06 pm-10:15 pm

3 stops31h 09m

$429

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 14 results
1
2

Compare providers for flights from San Antonio to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Santiago

What is the cheapest month to book a flight from San Antonio to Santiago?

Currently, September is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $260). Flying from San Antonio to Santiago in June is currently the most expensive (average of $673). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 12, 2025.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,009 reviews
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,889 reviews
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Santiago?

    A quick flight from San Antonio to Santiago can take about 22h 15m. American Airlines provides one of the quickest options available for as low as $714. San Antonio and Santiago are separated by a distance of 4706 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Antonio to Santiago round-trip?

    United Airlines, at $566, was found to be the cheapest airline from San Antonio to Santiago.Alternate airlines to your destination round-trip include American Airlines and Delta. United Airlines is priced at 42% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Santiago that include hotel bookings?

    Yes. In addition to deals on San Antonio to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Santiago.

  • Can I find deals for business class flights from San Antonio to Santiago?

    Yes. Cheapflights offers flight deals from San Antonio to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Santiago?

    Currently, September is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $260). Flying from San Antonio to Santiago in June is currently the most expensive (average of $673). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from San Antonio to Santiago

Discover the top 4 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$566Average$794FlexibilityNo cancel feeOn-time69%
DeltaCheapest$753Average$982FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$753Average$983FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$753Average$1,090FlexibilityNo cancel feeOn-time81%

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