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$326+ Cheap flights from San Antonio (SAT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from San Antonio to Santiago

Cheapest flights from San Antonio to Santiago
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:48 pmSAT - SCL
3 stops20h 42mLATAM Airlines
Mon 12/810:35 amSCL - SAT
2 stops16h 59mLATAM Airlines
Deal found 10/26$704
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/612:55 pmSAT - SCL
2 stops17h 05mAmerican Airlines
Wed 11/1910:25 pmSCL - SAT
2 stops16h 38mAmerican Airlines
Deal found 10/29$707
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/202:14 pmSAT - SCL
1 stop15h 36mUnited Airlines
Mon 11/2410:45 pmSCL - SAT
1 stop14h 58mUnited Airlines
Deal found 10/28$714
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/241:23 pmSAT - SCL
2 stops16h 27mUnited Airlines
Mon 12/110:45 pmSCL - SAT
1 stop12h 56mUnited Airlines
Deal found 10/26$719
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/54:52 pmSAT - SCL
2 stops19h 38mDelta
Mon 12/88:15 amSCL - SAT
2 stops19h 19mDelta
Deal found 10/27$754
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:37 pmSAT - SCL
3 stops31h 48mMultiple Airlines
Mon 11/247:25 amSCL - SAT
3 stops35h 34mMultiple Airlines
Deal found 10/27$769
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:00 amSAT - SCL
1 stop23h 45mAmerican Airlines
Thu 12/1811:15 pmSCL - SAT
1 stop21h 55mAmerican Airlines
Deal found 10/27$771
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:34 pmSAT - SCL
2 stops16h 16mUnited Airlines
Thu 12/1810:45 pmSCL - SAT
2 stops49h 15mUnited Airlines
Deal found 10/27$786
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:20 amSAT - SCL
1 stop23h 50mAmerican Airlines
Fri 12/1911:15 pmSCL - SAT
1 stop25h 35mAmerican Airlines
Deal found 10/27$797

Cheap flight deals from San Antonio to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$697
(FlightHub)

One-way from

$326
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$888
Provider with most accurate pricing for San Antonio-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Antonio-Santiago Arturo Merino Benitez flights.
Search Deals
From San Antonio to Santiago Arturo Merino Benitez
Search Deals
One-way flight from San Antonio to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($182 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.

Fly from

San Antonio

Fly to

Santiago

Route

Depart

Return

Price

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 1/11

6:22 pm-7:40 am

1 stop34h 18m

Santiago Arturo Merino Benitez

Tue 2/3

4:35 am-12:41 am

2 stops23h 06m

$704

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/13

1:40 pm-3:30 pm

2 stops22h 50m

Santiago Arturo Merino Benitez

Tue 2/3

8:15 am-12:41 am

2 stops19h 26m

$704

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 1/12

7:00 am-5:35 am

1 stop19h 35m

Santiago Arturo Merino Benitez

Wed 2/4

11:10 pm-3:22 pm

1 stop19h 12m

$704

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 1/12

1:40 pm-3:30 pm

2 stops22h 50m

Santiago Arturo Merino Benitez

Mon 2/2

11:10 pm-3:22 pm

1 stop19h 12m

$704

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 1/12

4:29 pm-7:40 am

1 stop12h 11m

Santiago Arturo Merino Benitez

Tue 2/3

8:15 am-12:41 am

2 stops19h 26m

$704

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/13

5:20 am-7:40 am

1 stop23h 20m

Santiago Arturo Merino Benitez

Wed 2/4

11:10 pm-10:02 am

1 stop13h 52m

$704

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

4:29 pm-7:40 am

1 stop12h 11m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-12:41 am

2 stops29h 26m

$714

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

4:29 pm-5:25 pm

2 stops21h 56m

Santiago Arturo Merino Benitez

Mon 2/2

6:30 pm-5:24 pm

2 stops25h 54m

$714

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 12/11

1:55 pm-2:05 pm

2 stops45h 10m

$326

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 11/9

8:40 pm-5:30 am

2 stops29h 50m

$342

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 13 results
1
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Compare providers for flights from San Antonio to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Santiago

What is the cheapest month to book a flight from San Antonio to Santiago?

Currently, September is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $260). Flying from San Antonio to Santiago in June is currently the most expensive (average of $673). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from San Antonio to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 29, 2025.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,993 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,993 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
LATAM Airlines
7.5
Good
1,872 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,030 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Santiago?

    A quick flight from San Antonio to Santiago can take about 34h 18m. Delta provides one of the quickest options available for as low as $704. San Antonio and Santiago are separated by a distance of 4706 mi.

  • What are the cheapest airlines flying from San Antonio to Santiago round-trip?

    United Airlines, at $566, was found to be the cheapest airline from San Antonio to Santiago.Alternate airlines to your destination round-trip include American Airlines and Delta. United Airlines is priced at 45% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Santiago that include hotel bookings?

    Yes. In addition to deals on San Antonio to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Santiago.

  • Can I find deals for business class flights from San Antonio to Santiago?

    Yes. Cheapflights offers flight deals from San Antonio to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Santiago?

    Currently, September is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $260). Flying from San Antonio to Santiago in June is currently the most expensive (average of $673). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from San Antonio to Santiago

Discover the top 4 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$566Average$918FlexibilityNo cancel feeOn-time69%
DeltaCheapest$753Average$948FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$753Average$983FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$753Average$1,090FlexibilityNo cancel feeOn-time81%

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