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$461+ Cheap flights from Portland (PDX) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — SCL
Apr 11 — Apr 181
Sat 4/11
Sat 4/18
1 adult, Economy
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Cheap flight deals from Portland to Santiago

Cheapest flights from Portland to Santiago
Explore the most affordable flight options available from Portland to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.

This eDestinos deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:34 pm
PDX
-
SCL
1 stop33h 01m
Multiple Airlines
Mon 7/2011:25 pm
SCL
-
PDX
1 stop20h 25m
Multiple Airlines
Deal found 3/8$928
This eDestinos deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:00 am
PDX
-
SCL
1 stop19h 35m
Multiple Airlines
Wed 7/1511:05 pm
SCL
-
PDX
2 stops22h 57m
Multiple Airlines
Deal found 3/8$947
This eDestinos deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:00 am
PDX
-
SCL
2 stops19h 25m
Multiple Airlines
Thu 7/1611:00 pm
SCL
-
PDX
2 stops23h 02m
Multiple Airlines
Deal found 3/8$961
This FlightHub deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:10 pm
PDX
-
SCL
2 stops21h 15m
LATAM Airlines
Wed 8/267:55 pm
SCL
-
PDX
2 stops19h 18m
LATAM Airlines
Deal found 3/10$980

Find flight deals from Portland to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$928
(eDestinos)

One-way from

$461
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$1,182
Provider with most accurate pricing for Portland-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Santiago Arturo Merino Benitez flights.
Search Deals
From Portland to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Portland to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($67 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 8/18

5:10 pm-5:25 pm

2 stops21h 15m

Santiago Arturo Merino Benitez

Wed 9/2

11:25 pm-12:13 pm

1 stop15h 48m

$1,004

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 8/3

10:00 am-5:35 am

1 stop16h 35m

Santiago Arturo Merino Benitez

Sun 8/23

6:45 pm-12:13 pm

2 stops20h 28m

$1,027

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 4/30

11:51 am-2:05 pm

2 stops23h 14m

Santiago Arturo Merino Benitez

Wed 5/13

11:25 pm-4:23 pm

1 stop19h 58m

$1,045

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 4/6

10:58 am-5:35 am

1 stop15h 37m

Santiago Arturo Merino Benitez

Mon 4/13

11:00 pm-7:05 pm

2 stops23h 05m

$1,057

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Fri 7/17

7:55 pm-5:35 am

1 stop30h 40m

Santiago Arturo Merino Benitez

Tue 8/4

10:55 pm-3:58 pm

2 stops20h 03m

$1,100

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Fri 7/17

7:55 pm-5:35 am

1 stop30h 40m

Santiago Arturo Merino Benitez

Sat 8/1

11:25 pm-12:13 pm

1 stop15h 48m

$1,131

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Fri 7/17

7:55 pm-5:35 am

1 stop30h 40m

Santiago Arturo Merino Benitez

Sun 8/2

11:25 pm-7:26 pm

1 stop23h 01m

$1,135

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 4/9

7:00 am-6:25 am

1 stop20h 25m

Santiago Arturo Merino Benitez

Sat 4/18

8:40 pm-10:41 am

1 stop17h 01m

$1,159
Cheapest one-way

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 4/7

7:00 am-1:30 pm

3 stops51h 30m

$484

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Fri 5/15

9:53 am-7:23 pm

2 stops54h 30m

$495

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/10

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Portland to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Santiago in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santiago

How far ahead should I book a flight from Portland to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Santiago. Price data was last updated on March 6, 2026.

Booking 24 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Portland to Santiago?

Currently, August is the cheapest month in which you can book a flight from Portland to Santiago (average of $758). Flying from Portland to Santiago in May is currently the most expensive (average of $1,197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Portland to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 12, 2026.
Read through reviews of airlines operating flights from Portland to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,286 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,286 reviews
Delta
7.9
Good
8,286 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.4
Good
1,917 reviews
Delta
7.9
Good
8,286 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,418 reviews
Delta
7.9
Good
8,286 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,432 reviews
Delta
7.9
Good
8,286 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Portland to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland to Santiago?

    Departing from Portland to Santiago will take you 21h 15m. There are 6340 mi between Portland and Santiago. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Portland to Santiago round-trip?

    According to our current data, LATAM Airlines ($874), United Airlines ($953), and Delta ($954) offers the cheapest pricing from Portland to Santiago. Users have found that LATAM Airlines is 22% cheaper than the other options available to this destination.

  • Can I find deals for flights from Portland to Santiago that include hotel bookings?

    Yes. In addition to deals on Portland to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santiago.

  • Can I find deals for business class flights from Portland to Santiago?

    Yes. Cheapflights offers flight deals from Portland to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Santiago?

    Currently, August is the cheapest month in which you can book a flight from Portland to Santiago (average of $758). Flying from Portland to Santiago in May is currently the most expensive (average of $1,197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Portland to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Portland to Easter Island flights
Redmond to Santiago flights

Top 4 airlines flying from Portland to Santiago

Discover the top 4 airlines that operate flights from Portland to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$874Average$1,103FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$953Average$995FlexibilityNo cancel feeOn-time69%
DeltaCheapest$954Average$1,163FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$973Average$1,173FlexibilityNo cancel feeOn-time71%

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