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$355+ Cheap flights from Portland (PDX) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — SCL
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheapflights Tip: The best prices from Portland to Santiago Arturo Merino Benitez are usually found in October or September, booked 40 days in advance, depart on a Monday or Tuesday and return on a Wednesday

Cheap flight deals from Portland to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$881
(FlightHub)

One-way from

$355
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$1,052
From Portland to Santiago Arturo Merino Benitez
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One-way flight from Portland to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 7% potential increase in price ($86 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Portland to Santiago

Cheapest flights from Portland to Santiago
Explore the most affordable flight options available from Portland to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:01 pmPDX - SCL
2 stops21h 29mLATAM Airlines
Thu 10/28:15 amSCL - PDX
1 stop19h 24mLATAM Airlines
Deal found 7/27$881
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1110:30 amPDX - SCL
1 stop16h 30mMultiple Airlines
Wed 9/1712:25 amSCL - PDX
2 stops24h 25mMultiple Airlines
Deal found 7/27$913
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1811:42 amPDX - SCL
1 stop15h 18mDelta
Wed 10/19:40 pmSCL - PDX
1 stop16h 52mDelta
Deal found 7/28$974
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/117:31 amPDX - SCL
2 stops20h 24mAmerican Airlines
Thu 9/189:55 pmSCL - PDX
2 stops20h 28mAmerican Airlines
Deal found 7/27$1,018
This CheapOair deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/289:50 amPDX - SCL
2 stops21h 25mAir Canada
Sat 12/138:55 pmSCL - PDX
2 stops41h 20mAir Canada
Deal found 7/28$1,046
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:00 amPDX - SCL
3 stops21h 50mUnited Airlines
Sat 12/1310:45 pmSCL - PDX
2 stops28h 41mUnited Airlines
Deal found 7/28$1,133

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.

Fly from

Portland

Fly to

Santiago

Route

Depart

Return

Price

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Wed 9/24

5:01 pm-6:30 pm

2 stops21h 29m

Santiago Arturo Merino Benitez

Thu 10/2

8:15 am-11:39 pm

1 stop19h 24m

$881

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 9/11

10:30 am-7:00 am

1 stop16h 30m

Santiago Arturo Merino Benitez

Wed 9/17

12:25 am-8:50 pm

2 stops24h 25m

$913

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 1/12

10:00 am-5:35 am

1 stop14h 35m

Santiago Arturo Merino Benitez

Mon 2/2

11:15 pm-7:18 pm

1 stop25h 03m

$964

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 9/11

7:31 am-7:55 am

2 stops20h 24m

Santiago Arturo Merino Benitez

Thu 9/18

9:55 pm-2:23 pm

2 stops20h 28m

$1,018

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Fri 11/28

9:50 am-12:15 pm

2 stops21h 25m

Santiago Arturo Merino Benitez

Sat 12/13

8:55 pm-9:15 am

2 stops41h 20m

$1,046

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Wed 8/6

3:10 pm-10:30 pm

3 stops28h 20m

$355

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 12/14

12:55 am-6:10 am

2 stops24h 15m

$668

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 12/21

7:45 pm-8:50 am

2 stops32h 05m

$699

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 8/5

7:00 am-6:45 am

1 stop20h 45m

$736

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 8/5

6:10 am-7:05 am

2 stops21h 55m

$758

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from Portland to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santiago

How far ahead should I book a flight from Portland to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Santiago. Price data was last updated on July 25, 2025.

Booking 40 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Portland to Santiago?

Currently, April is the cheapest month in which you can book a flight from Portland to Santiago (average of $752). Flying from Portland to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to SCL?

Find hourly flight availability from Portland to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 22% on flights from Portland to Santiago by exploring options for tickets in the afternoon.

How much does it cost to fly round-trip from Portland to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 29, 2025.
Read through reviews of airlines operating flights from Portland to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,822 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air Canada
7.1
Good
9,826 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Portland to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Portland to Santiago round-trip?

    According to our current data, LATAM Airlines ($881), Delta ($964), and American Airlines ($1,018) offers the cheapest pricing from Portland to Santiago. Users have found that LATAM Airlines is 22% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Portland to Santiago one-way?

    The cheapest airlines for a one-way flight from Portland to Santiago are Delta ($668), United Airlines ($699), and LATAM Airlines ($736).

  • Can I find deals for flights from Portland to Santiago that include hotel bookings?

    Yes. In addition to deals on Portland to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santiago.

  • Can I find deals for business class flights from Portland to Santiago?

    Yes. Cheapflights offers flight deals from Portland to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Portland to Santiago (average of $752). Flying from Portland to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Portland to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Medford to Santiago flights
Boise to Santiago flights
Portland to Punta Arenas flights
Redmond to Santiago flights
Portland to Easter Island flights
Portland to Temuco flights

Top 4 airlines flying from Portland to Santiago

Discover the top 4 airlines that operate flights from Portland to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$904Average$1,127FlexibilityNo cancel feeOn-time81%
DeltaCheapest$952Average$1,124FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$972Average$1,102FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$973Average$1,206FlexibilityNo cancel feeOn-time71%

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