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$357+ Cheap flights from Portland (PDX) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/26. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — SCL
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Portland to Santiago

Cheapest flights from Portland to Santiago
Explore the most affordable flight options available from Portland to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:00 am
PDX
-
SCL
2 stops20h 40m
Multiple Airlines
Mon 4/208:30 am
SCL
-
PDX
2 stops39h 05m
Multiple Airlines
Deal found 1/26$761
This FlightHub deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:00 am
PDX
-
SCL
1 stop20h 50m
LATAM Airlines
Tue 4/2811:05 pm
SCL
-
PDX
2 stops23h 00m
LATAM Airlines
Deal found 1/25$846
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/129:53 am
PDX
-
SCL
2 stops30h 27m
Multiple Airlines
Thu 3/1911:25 pm
SCL
-
PDX
1 stop25h 10m
Multiple Airlines
Deal found 1/25$863
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:00 am
PDX
-
SCL
2 stops37h 30m
Multiple Airlines
Wed 3/187:15 am
SCL
-
PDX
2 stops41h 20m
Multiple Airlines
Deal found 1/26$884
This eDestinos deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:40 am
PDX
-
SCL
1 stop16h 00m
Multiple Airlines
Tue 5/2611:25 pm
SCL
-
PDX
1 stop17h 18m
Multiple Airlines
Deal found 1/25$911
This FlightHub deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/111:10 pm
PDX
-
SCL
2 stops21h 35m
LATAM Airlines
Tue 4/2111:25 pm
SCL
-
PDX
1 stop15h 41m
LATAM Airlines
Deal found 1/26$927
This FlightHub deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:00 am
PDX
-
SCL
1 stop20h 50m
LATAM Airlines
Wed 8/2611:25 pm
SCL
-
PDX
1 stop15h 48m
LATAM Airlines
Deal found 1/27$929
This Air Canada deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:10 pm
PDX
-
SCL
2 stops37h 05m
Air Canada
Tue 11/38:55 pm
SCL
-
PDX
2 stops22h 45m
Air Canada
Deal found 1/25$949

Find flight deals from Portland to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$761
(Kiwi.com)

One-way from

$357
(flugladen.de)

Popular in

June

Cheapest in

January

Average price

$973
Provider with most accurate pricing for Portland-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Santiago Arturo Merino Benitez flights.
Search Deals
From Portland to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Portland to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.

Fly from

Portland

Fly to

Santiago

Route

Depart

Return

Price

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 4/14

6:30 am-4:50 am

2 stops19h 20m

Santiago Arturo Merino Benitez

Tue 4/28

7:45 pm-12:06 pm

2 stops19h 21m

$846

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 3/12

9:53 am-8:20 pm

2 stops30h 27m

Santiago Arturo Merino Benitez

Thu 3/19

11:25 pm-8:35 pm

1 stop25h 10m

$863

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sat 4/11

10:58 am-1:45 pm

2 stops23h 47m

Santiago Arturo Merino Benitez

Tue 4/21

11:25 pm-12:06 pm

1 stop15h 41m

$927

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 5/31

5:40 pm-5:35 am

1 stop32h 55m

Santiago Arturo Merino Benitez

Sun 6/7

9:25 pm-11:44 pm

2 stops29h 19m

$954

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 4/30

9:53 am-5:35 am

1 stop16h 42m

Santiago Arturo Merino Benitez

Mon 5/4

11:17 am-9:38 am

2 stops25h 21m

$962

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 5/31

7:55 pm-5:35 am

1 stop30h 40m

Santiago Arturo Merino Benitez

Sun 6/7

10:55 pm-9:35 pm

1 stop25h 40m

$977

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/9

7:00 am-5:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Thu 3/19

11:55 pm-12:14 pm

1 stop16h 19m

$977

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 3/26

12:04 pm-6:40 am

3 stops38h 36m

$424

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/2

7:16 pm-7:40 am

2 stops31h 24m

$450

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 3/22

10:30 pm-6:45 am

2 stops28h 15m

$470

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 14 results
1
2

Compare providers for flights from Portland to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Santiago in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santiago

How far ahead should I book a flight from Portland to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Santiago. Price data was last updated on January 23, 2026.

Booking 24 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Portland to Santiago?

Currently, August is the cheapest month in which you can book a flight from Portland to Santiago (average of $758). Flying from Portland to Santiago in May is currently the most expensive (average of $1,197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Portland to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 27, 2026.
Read through reviews of airlines operating flights from Portland to Santiago, such as Delta, LATAM Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,119 reviews

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,119 reviews
Delta
7.9
Good
8,119 reviews

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,912 reviews
Delta
7.9
Good
8,119 reviews

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,119 reviews

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Portland to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland to Santiago?

    Departing from Portland to Santiago will take you 18h 10m. There are 6340 mi between Portland and Santiago.

  • What are the cheapest airlines flying from Portland to Santiago round-trip?

    According to our current data, LATAM Airlines ($874), Delta ($954), and American Airlines ($973) offers the cheapest pricing from Portland to Santiago. Users have found that LATAM Airlines is 23% cheaper than the other options available to this destination.

  • Can I find deals for flights from Portland to Santiago that include hotel bookings?

    Yes. In addition to deals on Portland to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santiago.

  • Can I find deals for business class flights from Portland to Santiago?

    Yes. Cheapflights offers flight deals from Portland to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Santiago?

    Currently, August is the cheapest month in which you can book a flight from Portland to Santiago (average of $758). Flying from Portland to Santiago in May is currently the most expensive (average of $1,197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Portland to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Medford to Santiago flights
Redmond to Santiago flights
Boise to Santiago flights
Portland to Easter Island flights
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Portland to Temuco flights

Top 3 airlines flying from Portland to Santiago

Discover the top 3 airlines that operate flights from Portland to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$874Average$1,175FlexibilityNo cancel feeOn-time81%
DeltaCheapest$954Average$1,198FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$973Average$1,173FlexibilityNo cancel feeOn-time71%

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