Santiago

$416+ Cheap flights from New Orleans (MSY) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/26. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — SCL
Oct 11 — Oct 181
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Cheap flight deals from New Orleans to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from New Orleans (MSY) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$794
(FlightHub)

One-way from

$416
(Kiwi.com)

Popular in

June

Cheapest in

October

Average price

$843
From New Orleans Louis Armstrong to Santiago Arturo Merino Benitez
One-way flight from New Orleans Louis Armstrong to Santiago Arturo Merino Benitez
Highest demand for flights based on searches. 35% potential increase in price ($541 potential increase over avg. RT price).
Cheapest flight prices on average. 22% potential price decrease ($182 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from New Orleans to Santiago

Cheapest flights from New Orleans to Santiago
Explore the most affordable flight options available from New Orleans to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:43 amMSY - SCL
1 stop16h 27mLATAM Airlines
Thu 12/186:40 amSCL - MSY
2 stops18h 42mLATAM Airlines
Deal found 9/11$794
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:15 amMSY - SCL
1 stop22h 25mLATAM Airlines
Wed 12/3112:25 amSCL - MSY
2 stops26h 12mLATAM Airlines
Deal found 9/11$1,014
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:26 pmMSY - SCL
2 stops19h 04mDelta
Thu 1/110:35 amSCL - MSY
2 stops16h 02mDelta
Deal found 9/11$1,218
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:45 pmMSY - SCL
1 stop13h 15mMultiple Airlines
Sat 1/35:55 amSCL - MSY
2 stops34h 45mMultiple Airlines
Deal found 9/11$1,308
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:45 pmMSY - SCL
1 stop13h 15mMultiple Airlines
Thu 1/19:10 pmSCL - MSY
2 stops19h 30mMultiple Airlines
Deal found 9/11$1,314
This KAYAK deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:15 amMSY - SCL
2 stops20h 35mLATAM Airlines
Wed 12/3112:25 amSCL - MSY
2 stops26h 12mLATAM Airlines
Deal found 9/11$1,342
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:20 pmMSY - SCL
1 stop34h 30mUnited Airlines
Thu 1/110:45 pmSCL - MSY
1 stop12h 51mUnited Airlines
Deal found 9/11$1,357
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/212:45 pmMSY - SCL
1 stop13h 15mMultiple Airlines
Sat 1/35:55 amSCL - MSY
2 stops34h 45mMultiple Airlines
Deal found 9/11$1,376
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/212:45 pmMSY - SCL
1 stop13h 15mMultiple Airlines
Thu 1/19:10 pmSCL - MSY
2 stops19h 30mMultiple Airlines
Deal found 9/11$1,381

Cheapflights Fare Finder

 
Customize your flight search to find flights from New Orleans to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from New Orleans to Santiago that are best for you.

Fly from

New Orleans

Fly to

Santiago

Route

Depart

Return

Price

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Fri 12/12

10:43 am-7:40 am

1 stop17h 57m

Santiago Arturo Merino Benitez

Thu 12/18

9:30 pm-8:13 am

1 stop13h 43m

$794

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Sat 1/3

5:26 pm-5:30 pm

2 stops21h 04m

Santiago Arturo Merino Benitez

Tue 1/13

6:30 pm-1:09 pm

3 stops21h 39m

$844

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Sat 1/3

2:14 pm-8:50 am

1 stop15h 36m

Santiago Arturo Merino Benitez

Wed 1/14

10:45 pm-8:56 am

1 stop13h 11m

$925

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Fri 1/2

5:07 pm-8:50 am

1 stop12h 43m

Santiago Arturo Merino Benitez

Wed 1/14

10:45 pm-8:56 am

1 stop13h 11m

$925

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Sat 1/3

10:42 am-6:10 am

1 stop16h 28m

Santiago Arturo Merino Benitez

Tue 1/13

12:25 am-4:21 pm

2 stops18h 56m

$929

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Sat 1/3

5:26 pm-6:10 am

1 stop33h 44m

Santiago Arturo Merino Benitez

Mon 1/12

12:25 am-11:27 pm

2 stops26h 02m

$931

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Fri 1/2

3:42 pm-8:50 am

1 stop14h 08m

Santiago Arturo Merino Benitez

Mon 1/12

10:45 pm-1:09 pm

1 stop17h 24m

$990

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Sat 1/3

2:14 pm-8:50 am

1 stop15h 36m

Santiago Arturo Merino Benitez

Mon 1/12

10:45 pm-10:52 am

1 stop15h 07m

$990

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Fri 1/2

6:55 pm-9:05 am

1 stop11h 10m

Santiago Arturo Merino Benitez

Tue 1/13

10:15 pm-12:15 pm

2 stops17h 00m

$1,118

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Fri 12/26

2:45 pm-12:15 pm

3 stops42h 30m

$416

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 11 results
1
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Best time to book a flight from New Orleans to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from New Orleans with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Santiago

What is the cheapest month to book a flight from New Orleans to Santiago?

Currently, April is the cheapest month in which you can book a flight from New Orleans to Santiago (average of $752). Flying from New Orleans to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSY to SCL?

Find hourly flight availability from New Orleans to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from New Orleans to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 21% versus a flight in the afternoon.

How much does it cost to fly round-trip from New Orleans to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines, and American Airlines from New Orleans to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from New Orleans to Santiago?

    For as low as $794, LATAM Airlines can have you in Santiago from New Orleans in 17h 57m. The distance between New Orleans and Santiago is about 4557 mi.

  • What are the cheapest airlines flying from New Orleans to Santiago round-trip?

    American Airlines, at $652, was found to be the cheapest airline from New Orleans to Santiago.Alternate airlines to your destination round-trip include Delta and LATAM Airlines. American Airlines is currently priced 33% below the average price you’ll pay for this route.

  • Can I find deals for flights from New Orleans to Santiago that include hotel bookings?

    Yes. In addition to deals on New Orleans to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from New Orleans to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Santiago.

  • Can I find deals for business class flights from New Orleans to Santiago?

    Yes. Cheapflights offers flight deals from New Orleans to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from New Orleans to Santiago?

    Currently, April is the cheapest month in which you can book a flight from New Orleans to Santiago (average of $752). Flying from New Orleans to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for New Orleans to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from New Orleans to Santiago

Discover the top 3 airlines that operate flights from New Orleans to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$652Average$883FlexibilityNo cancel feeOn-time71%
DeltaCheapest$652Average$757FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$708Average$843FlexibilityNo cancel feeOn-time81%

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