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$858+ Cheap flights from Lexington (LEX) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — SCL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Lexington to Santiago

Cheapest flights from Lexington to Santiago
Explore the most affordable flight options available from Lexington to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:00 am
LEX
-
SCL
1 stop23h 00m
American Airlines
Wed 3/2510:15 pm
SCL
-
LEX
1 stop16h 08m
American Airlines
Deal found 1/28$858
This LATAM Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:55 pm
LEX
-
SCL
2 stops33h 50m
LATAM Airlines
Thu 3/124:35 am
SCL
-
LEX
2 stops20h 18m
LATAM Airlines
Deal found 1/26$888
This Expedia deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/164:14 pm
LEX
-
SCL
2 stops20h 51m
LATAM Airlines
Wed 3/257:15 am
SCL
-
LEX
3 stops29h 39m
LATAM Airlines
Deal found 1/28$903
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:41 pm
LEX
-
SCL
2 stops37h 09m
United Airlines
Thu 3/129:45 pm
SCL
-
LEX
2 stops16h 30m
United Airlines
Deal found 1/27$904

Find flight deals from Lexington to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$858
(American Airlines)
Provider with most accurate pricing for Lexington Blue Grass-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lexington Blue Grass-Santiago Arturo Merino Benitez flights.
Search Deals
From Lexington Blue Grass to Santiago Arturo Merino Benitez
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Lexington to Santiago that are best for you.

Fly from

Lexington

Fly to

Santiago

Route

Depart

Return

Price

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Mon 3/16

7:00 am-7:00 am

1 stop23h 00m

Santiago Arturo Merino Benitez

Tue 3/24

10:15 pm-6:40 pm

1 stop21h 25m

$858

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Mon 3/16

7:00 am-7:00 am

1 stop23h 00m

Santiago Arturo Merino Benitez

Wed 3/25

9:20 pm-5:16 pm

2 stops20h 56m

$863

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Sun 3/8

7:55 pm-6:45 am

2 stops33h 50m

Santiago Arturo Merino Benitez

Thu 3/12

4:35 am-11:53 pm

2 stops20h 18m

$888

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Mon 3/16

4:14 pm-2:05 pm

2 stops20h 51m

Santiago Arturo Merino Benitez

Wed 3/25

7:15 am-11:54 am

3 stops29h 39m

$903

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Mon 3/16

7:55 pm-11:25 pm

2 stops26h 30m

Santiago Arturo Merino Benitez

Tue 3/24

7:15 am-11:54 am

3 stops29h 39m

$903

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Sun 3/8

5:41 pm-7:50 am

2 stops37h 09m

Santiago Arturo Merino Benitez

Thu 3/12

9:45 pm-1:15 pm

2 stops16h 30m

$904

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Compare providers for flights from Lexington to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lexington to Santiago in January.
ProviderPrice AccuracyTrust Score*
OvagoPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lexington-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lexington-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lexington-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lexington-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lexington-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lexington to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Santiago

What is the cheapest month to book a flight from Lexington to Santiago?

Currently, November is the cheapest month in which you can book a flight from Lexington to Santiago (average of $549). Flying from Lexington to Santiago in May is currently the most expensive (average of $1,017). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Lexington to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Santiago?

    Departing from Lexington to Santiago will take you 23h. Lexington and Santiago are separated by a distance of 5011 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Lexington to Santiago that include hotel bookings?

    Yes. In addition to deals on Lexington to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Santiago.

  • Can I find deals for business class flights from Lexington to Santiago?

    Yes. Cheapflights offers flight deals from Lexington to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Lexington to Santiago (average of $549). Flying from Lexington to Santiago in May is currently the most expensive (average of $1,017). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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