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$828+ Cheap flights from Lexington (LEX) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — SCL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Lexington to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$828
(United Airlines)
From Lexington Blue Grass to Santiago Arturo Merino Benitez
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Find flight deals from Lexington to Santiago

Cheapest flights from Lexington to Santiago
Explore the most affordable flight options available from Lexington to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:10 pmLEX - SCL
2 stops16h 40mUnited Airlines
Fri 12/510:45 pmSCL - LEX
2 stops25h 45mUnited Airlines
Deal found 9/9$828
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/21:07 pmLEX - SCL
1 stop16h 33mDelta
Fri 12/511:10 pmSCL - LEX
1 stop17h 43mDelta
Deal found 9/10$884
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:38 pmLEX - SCL
1 stop14h 02mLATAM Airlines
Tue 1/64:40 pmSCL - LEX
2 stops33h 15mLATAM Airlines
Deal found 9/10$1,259
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:52 pmLEX - SCL
1 stop11h 48mLATAM Airlines
Mon 1/54:40 pmSCL - LEX
2 stops33h 15mLATAM Airlines
Deal found 9/10$1,324
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:52 pmLEX - SCL
1 stop34h 18mDelta
Tue 1/69:30 pmSCL - LEX
1 stop14h 58mDelta
Deal found 9/10$1,506
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:09 amLEX - SCL
2 stops24h 56mAmerican Airlines
Fri 1/210:15 pmSCL - LEX
2 stops25h 46mAmerican Airlines
Deal found 9/10$1,574
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:09 amLEX - SCL
2 stops24h 56mAmerican Airlines
Sun 1/410:15 pmSCL - LEX
2 stops21h 18mAmerican Airlines
Deal found 9/10$1,716

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Lexington to Santiago that are best for you.

Fly from

Lexington

Fly to

Santiago

Route

Depart

Return

Price

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Tue 12/2

2:10 pm-8:50 am

2 stops16h 40m

Santiago Arturo Merino Benitez

Fri 12/5

10:45 pm-10:30 pm

2 stops25h 45m

$828

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Tue 12/2

5:15 pm-2:05 pm

2 stops18h 50m

Santiago Arturo Merino Benitez

Fri 12/5

11:10 pm-12:22 pm

1 stop15h 12m

$884

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Tue 12/2

3:38 pm-7:40 am

1 stop14h 02m

Santiago Arturo Merino Benitez

Fri 12/5

11:10 pm-9:28 am

1 stop12h 18m

$884

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Tue 12/23

3:38 pm-7:40 am

1 stop14h 02m

Santiago Arturo Merino Benitez

Tue 1/6

4:40 pm-11:55 pm

2 stops33h 15m

$1,259

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Lexington to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Santiago

What is the cheapest month to book a flight from Lexington to Santiago?

Currently, April is the cheapest month in which you can book a flight from Lexington to Santiago (average of $752). Flying from Lexington to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Lexington to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Santiago?

    Departing from Lexington to Santiago will take you 14h 02m. Lexington and Santiago are separated by a distance of 5011 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Lexington to Santiago that include hotel bookings?

    Yes. In addition to deals on Lexington to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Santiago.

  • Can I find deals for business class flights from Lexington to Santiago?

    Yes. Cheapflights offers flight deals from Lexington to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Lexington to Santiago (average of $752). Flying from Lexington to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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