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$431+ Cheap flights from Harrisburg (MDT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SCL
Aug 26 — Sep 21
Tue 8/26
Tue 9/2
1 adult, Economy
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Cheap flight deals from Harrisburg to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2025.

Round-trip from

$824
(LATAM Airlines)

One-way from

$431
(Kiwi.com)
From Harrisburg to Santiago Arturo Merino Benitez
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One-way flight from Harrisburg to Santiago Arturo Merino Benitez
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Find flight deals from Harrisburg to Santiago

Cheapest flights from Harrisburg to Santiago
Explore the most affordable flight options available from Harrisburg to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2025.

This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/812:25 pmMDT - SCL
1 stop16h 35mDelta
Fri 12/129:30 pmSCL - MDT
1 stop17h 32mDelta
Deal found 8/20$824

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from Harrisburg to Santiago that are best for you.

Fly from

Harrisburg

Fly to

Santiago

Route

Depart

Return

Price

HarrisburgSantiago

MDT - SCL

MDTSCL

Harrisburg

Mon 12/8

6:00 am-7:00 am

1 stop23h 00m

Santiago Arturo Merino Benitez

Fri 12/12

11:15 pm-1:02 pm

1 stop15h 47m

$824

HarrisburgSantiago

MDT - SCL

MDTSCL

Harrisburg

Mon 12/8

12:25 pm-7:00 am

1 stop16h 35m

Santiago Arturo Merino Benitez

Fri 12/12

9:30 pm-1:02 pm

1 stop17h 32m

$824

HarrisburgSantiago

MDT - SCL

MDTSCL

Harrisburg

Sun 9/7

12:17 pm-5:15 am

3 stops39h 58m

$431

HarrisburgSantiago

MDT - SCL

MDTSCL

Harrisburg

Sun 9/7

11:39 am-7:00 am

1 stop18h 21m

$635

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/21

Best time to book a flight from Harrisburg to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Santiago

What is the cheapest month to book a flight from Harrisburg to Santiago?

Currently, April is the cheapest month in which you can book a flight from Harrisburg to Santiago (average of $752). Flying from Harrisburg to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Santiago?

    For as low as $824, LATAM Airlines can have you in Santiago from Harrisburg in 23h. The distance from Harrisburg to Santiago is about 5095 mi.

  • Can I find deals for flights from Harrisburg to Santiago that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Santiago.

  • Can I find deals for business class flights from Harrisburg to Santiago?

    Yes. Cheapflights offers flight deals from Harrisburg to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Harrisburg to Santiago (average of $752). Flying from Harrisburg to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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