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$1,065+ Cheap flights from Harrisburg (MDT) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SCL
Jun 5 — Jun 121
Fri 6/5
Fri 6/12
1 adult, Economy
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Cheap flight deals from Harrisburg to Santiago

Cheapest flights from Harrisburg to Santiago
Explore the most affordable flight options available from Harrisburg to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.

This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am
MDT
-
SCL
2 stops24h 50m
United Airlines
Mon 12/710:45 pm
SCL
-
MDT
2 stops17h 04m
United Airlines
Deal found 5/5$1,065
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:24 am
MDT
-
SCL
2 stops22h 36m
American Airlines
Thu 8/138:30 pm
SCL
-
MDT
2 stops25h 05m
American Airlines
Deal found 5/5$1,130
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:36 am
MDT
-
SCL
2 stops20h 24m
American Airlines
Wed 7/159:00 pm
SCL
-
MDT
2 stops17h 00m
American Airlines
Deal found 5/5$1,165
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1811:41 am
MDT
-
SCL
2 stops19h 19m
American Airlines
Sat 8/88:30 pm
SCL
-
MDT
2 stops24h 00m
American Airlines
Deal found 5/4$1,180
This KAYAK deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:22 pm
MDT
-
SCL
1 stop12h 53m
LATAM Airlines
Wed 7/154:30 pm
SCL
-
MDT
2 stops31h 23m
LATAM Airlines
Deal found 5/5$1,187
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:22 pm
MDT
-
SCL
1 stop12h 53m
Delta
Wed 7/158:40 pm
SCL
-
MDT
1 stop20h 57m
Delta
Deal found 5/6$1,195
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 am
MDT
-
SCL
2 stops24h 50m
United Airlines
Thu 11/1210:45 pm
SCL
-
MDT
2 stops36h 39m
United Airlines
Deal found 5/1$1,250
This KAYAK deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2512:30 pm
MDT
-
SCL
2 stops32h 25m
LATAM Airlines
Thu 8/138:40 pm
SCL
-
MDT
1 stop14h 28m
LATAM Airlines
Deal found 5/6$1,337
This KAYAK deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:22 pm
MDT
-
SCL
1 stop12h 53m
LATAM Airlines
Sat 8/811:05 pm
SCL
-
MDT
2 stops36h 03m
LATAM Airlines
Deal found 5/4$1,348

Find flight deals from Harrisburg to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 6, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$1,130
(American Airlines)
Provider with most accurate pricing for Harrisburg-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Santiago Arturo Merino Benitez flights.
Search Deals
From Harrisburg to Santiago Arturo Merino Benitez
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Harrisburg to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgSantiago

MDT - SCL

MDTSCL

Harrisburg

Sat 7/25

8:15 am-7:00 am

2 stops22h 45m

Santiago Arturo Merino Benitez

Thu 8/13

8:30 pm-7:45 pm

2 stops23h 15m

$1,130
Quickest round-trip

HarrisburgSantiago

MDT - SCL

MDTSCL

Harrisburg

Wed 7/1

10:36 am-7:00 am

2 stops20h 24m

Santiago Arturo Merino Benitez

Wed 7/15

9:00 pm-6:57 pm

2 stops21h 57m

$1,165

HarrisburgSantiago

MDT - SCL

MDTSCL

Harrisburg

Sat 7/18

11:41 am-7:00 am

2 stops19h 19m

Santiago Arturo Merino Benitez

Sat 8/8

8:30 pm-8:30 pm

2 stops24h 00m

$1,180

HarrisburgSantiago

MDT - SCL

MDTSCL

Harrisburg

Wed 7/1

11:56 am-7:15 am

1 stop19h 19m

Santiago Arturo Merino Benitez

Wed 7/15

11:05 pm-11:53 pm

2 stops24h 48m

$1,187

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/6

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Harrisburg-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Harrisburg-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Harrisburg-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Santiago?

    For as low as $1,130, American Airlines can have you in Santiago from Harrisburg in 22h 45m. The distance from Harrisburg to Santiago is about 5095 mi.

  • Can I find deals for flights from Harrisburg to Santiago that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Santiago.

  • Can I find deals for business class flights from Harrisburg to Santiago?

    Yes. Cheapflights offers flight deals from Harrisburg to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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