HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$227+ Cheap flights from Guayaquil (GYE) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SCL
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Guayaquil to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez are usually found in August or May, booked 3 days in advance, depart on a Thursday or Tuesday and return on a Monday

Cheap flight deals from Guayaquil to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 1, 2025.

Most accurate provider

Flightnetwork
3 stars

Most trusted provider

Flightnetwork
3 stars

Round-trip from

$348
(Booking.com)

One-way from

$227
(LATAM Airlines)

Popular in

February

Cheapest in

August

Average price

$346

Good round-trip deal

$504 or less

Good one-way deal

$351 or less
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Santiago Arturo Merino Benitez flights.
Search Deals
From Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
Search Deals
Price to beat on a round-trip flight from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez.
Search Deals
Price to beat on a one-way flight from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez.
Search Deals

Find flight deals from Guayaquil to Santiago

Cheapest flights from Guayaquil to Santiago
Explore the most affordable flight options available from Guayaquil to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Priceline deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/23:35 amGYE - SCL
1 stop8h 50mAvianca
Tue 7/292:30 pmSCL - GYE
1 stop9h 10mAvianca
Deal found 4/30$348
This Booking.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/183:35 amGYE - SCL
1 stop8h 50mMultiple Airlines
Thu 5/225:35 amSCL - GYE
1 stop9h 40mMultiple Airlines
Deal found 4/28$349
This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/182:45 pmGYE - SCL
Nonstop4h 53mLATAM Airlines
Sun 7/274:15 amSCL - GYE
1 stop7h 55mLATAM Airlines
Deal found 4/30$363
This Copa Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/32:45 pmGYE - SCL
1 stop11h 02mCopa Airlines
Tue 9/211:27 amSCL - GYE
1 stop13h 12mCopa Airlines
Deal found 4/29$426

Cheapflights Fare Finder

Customize your flight search to find flights from Guayaquil to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Guayaquil to Santiago that are best for you.

Fly from

Guayaquil

Fly to

Santiago

Route

Depart

Return

Price

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Mon 6/2

3:35 am-1:25 pm

1 stop8h 50m

Santiago Arturo Merino Benitez

Tue 7/29

2:30 pm-10:40 pm

1 stop9h 10m

$348

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Sun 5/18

3:35 am-1:25 pm

1 stop8h 50m

Santiago Arturo Merino Benitez

Thu 5/22

5:35 am-2:15 pm

1 stop9h 40m

$349

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Fri 7/18

2:45 pm-8:38 pm

Nonstop4h 53m

Santiago Arturo Merino Benitez

Sun 7/27

4:15 am-11:10 am

1 stop7h 55m

$363

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Tue 6/3

2:45 pm-2:47 am

1 stop11h 02m

Santiago Arturo Merino Benitez

Tue 9/2

11:27 am-11:39 pm

1 stop13h 12m

$426

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Thu 6/19

12:55 pm-7:00 am

2 stops17h 05m

$227

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Tue 10/14

12:14 pm-3:43 am

1 stop13h 29m

$244

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Wed 6/18

3:35 am-1:25 pm

1 stop8h 50m

$306

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Thu 5/29

3:35 am-5:35 pm

2 stops13h 00m

$416

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Compare providers for flights from Guayaquil to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to Santiago in May.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
Trip.comPrice Accuracy1 starTrust Score*3 stars
FlightnetworkPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Guayaquil-Santiago flights, users find the pricing of Flightnetwork to be most consistent on Cheapflights vs. Flightnetwork Users can find the same prices on Guayaquil-Santiago flight deals on Cheapflights vs. Flightnetwork >95% of the time. Price accuracy is based on data collected from Guayaquil-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Guayaquil-Santiago flights, Cheapflights users trust Flightnetwork the most. Flightnetwork has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Guayaquil to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to Santiago

How far ahead should I book a flight from Guayaquil to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Guayaquil to Santiago. Price data was last updated on April 25, 2025.

To ensure you get the cheapest price possible for a flight from Guayaquil to Santiago, you should look to book at least 3 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Guayaquil to Santiago?

Currently, April is the cheapest month in which you can book a flight from Guayaquil to Santiago (average of $752). Flying from Guayaquil to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to SCL?

Find hourly flight availability from Guayaquil to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 32% on flights from Guayaquil to Santiago by exploring options for tickets in the morning.

What is the cheapest day to fly from Guayaquil to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Guayaquil to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Guayaquil to Santiago flight should consider departing on Sunday evenings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 1, 2025.
Read reviews from past customers who have flown LATAM Airlines, Copa Airlines and Avianca from Guayaquil to Santiago. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,767 reviews

Overall

7.5

Entertainment

7.0

Comfort

7.4

Boarding

7.6

Crew

8.1

Food

6.7

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2025

COR - LIM

Always a great service. Better than Delta or American Airlines
LATAM Airlines
7.5
Good
1,767 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Overall

7.5

Entertainment

7.0

Comfort

7.4

Boarding

7.6

Crew

8.1

Food

6.7

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2025

COR - LIM

Always a great service. Better than Delta or American Airlines
Copa Airlines
7.5
Good
1,415 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Overall

7.5

Entertainment

7.0

Comfort

7.4

Boarding

7.6

Crew

8.1

Food

6.7

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2025

COR - LIM

Always a great service. Better than Delta or American Airlines
Avianca
6.7
Okay
2,317 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Overall

7.5

Entertainment

7.0

Comfort

7.4

Boarding

7.6

Crew

8.1

Food

6.7

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2025

COR - LIM

Always a great service. Better than Delta or American Airlines

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Guayaquil to Santiago flight route?

    Flights from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez have been viewed 1 times in the past calendar month.

  • What are the cheapest airlines flying from Guayaquil to Santiago round-trip?

    LATAM Airlines, at $353, was found to be the cheapest airline from Guayaquil to Santiago.Alternate airlines to your destination round-trip include Avianca and Copa Airlines. These flights start at 7% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Guayaquil to Santiago one-way?

    The cheapest airlines for a one-way flight from Guayaquil to Santiago are LATAM Airlines ($227), Copa Airlines ($244), and Avianca ($334).

  • What are the cheapest flights from Guayaquil to Santiago?

    Looking at all options, your cheapest flight can be booked for $255. While the most popular route (Guayaquil Jose Joaquin de Olmedo - Santiago Arturo Merino Benitez) can be booked for $408 on average our data indicates $1,121 when flying from Guayaquil to Santiago.

  • Can I find deals for flights from Guayaquil to Santiago that include hotel bookings?

    Yes. In addition to deals on Guayaquil to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to Santiago.

  • Can I find deals for business class flights from Guayaquil to Santiago?

    Yes. Cheapflights offers flight deals from Guayaquil to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Guayaquil to Santiago (average of $752). Flying from Guayaquil to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Guayaquil to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Quito to Santiago flights

Top 3 airlines flying from Guayaquil to Santiago

Discover the top 3 airlines that operate flights from Guayaquil to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetSMARTCheapest$164Average$320FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$249Average$364FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$263Average$437FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.