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$188+ Cheap flights from Florida Keys to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SCL
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Florida Keys to Santiago

Keep the following information in mind while searching for Florida Keys to Santiago flight deals. Data was last updated September 17, 2025.

Round-trip from

$391
(Justfly.com)

One-way from

$188
(Booking.com)
From Florida Keys to Santiago Arturo Merino Benitez
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One-way flight from Florida Keys to Santiago Arturo Merino Benitez
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Find flight deals from Florida Keys to Santiago

Cheapest flights from Florida Keys to Santiago
Explore the most affordable flight options available from Florida Keys to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Justfly.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/149:45 amMIA - SCL
1 stop11h 30mMultiple Airlines
Tue 10/289:05 pmSCL - MIA
1 stop12h 15mMultiple Airlines
Deal found 9/14$391
This eDestinos deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/299:45 amMIA - SCL
1 stop19h 15mMultiple Airlines
Thu 10/95:55 amSCL - MIA
1 stop27h 25mMultiple Airlines
Deal found 9/14$395
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/39:45 amMIA - SCL
1 stop11h 30mMultiple Airlines
Tue 10/79:15 pmSCL - MIA
1 stop12h 05mMultiple Airlines
Deal found 9/17$409
This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:45 amMIA - SCL
2 stops25h 30mMultiple Airlines
Thu 11/69:05 pmSCL - MIA
1 stop20h 45mMultiple Airlines
Deal found 9/15$410
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:45 amMIA - SCL
1 stop11h 30mMultiple Airlines
Thu 10/1612:30 pmSCL - MIA
1 stop20h 50mMultiple Airlines
Deal found 9/15$413
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:45 amMIA - SCL
1 stop19h 15mMultiple Airlines
Mon 10/2012:30 pmSCL - MIA
1 stop20h 50mMultiple Airlines
Deal found 9/16$416
This Gotogate deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/245:10 pmMIA - SCL
2 stops17h 05mMultiple Airlines
Mon 12/112:30 pmSCL - MIA
1 stop20h 50mMultiple Airlines
Deal found 9/16$417
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/109:45 amMIA - SCL
1 stop28h 00mMultiple Airlines
Thu 10/231:35 amSCL - MIA
2 stops16h 30mMultiple Airlines
Deal found 9/16$418
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:45 amMIA - SCL
1 stop27h 55mMultiple Airlines
Thu 11/61:35 amSCL - MIA
2 stops31h 45mMultiple Airlines
Deal found 9/16$420
This Booking.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/286:25 pmMIA - SCL
1 stop19h 20mMultiple Airlines
Wed 10/81:40 amSCL - MIA
2 stops31h 40mMultiple Airlines
Deal found 9/14$421
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/79:45 amMIA - SCL
2 stops25h 35mMultiple Airlines
Sun 10/1212:30 pmSCL - MIA
1 stop29h 35mMultiple Airlines
Deal found 9/16$422

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Florida Keys to Santiago that are best for you.

Fly from

Florida Keys

Fly to

Santiago

Route

Depart

Return

Price

MiamiSantiago

MIA - SCL

MIASCL

Miami

Sun 9/28

1:40 am-6:30 pm

1 stop15h 50m

Santiago Arturo Merino Benitez

Thu 10/9

10:55 pm-6:30 am

Nonstop8h 35m

$575

MiamiSantiago

MIA - SCL

MIASCL

Miami

Tue 9/30

1:40 am-1:20 pm

1 stop10h 40m

Santiago Arturo Merino Benitez

Wed 10/15

11:00 am-6:35 pm

Nonstop8h 35m

$575

MiamiSantiago

MIA - SCL

MIASCL

Miami

Tue 10/14

9:40 pm-6:50 am

Nonstop8h 10m

Santiago Arturo Merino Benitez

Mon 10/27

12:20 am-11:51 am

1 stop12h 31m

$575

MiamiSantiago

MIA - SCL

MIASCL

Miami

Sun 9/28

1:40 am-1:20 pm

1 stop10h 40m

Santiago Arturo Merino Benitez

Thu 10/16

11:00 am-6:35 pm

Nonstop8h 35m

$575

MiamiSantiago

MIA - SCL

MIASCL

Miami

Sun 9/28

1:40 am-3:00 pm

1 stop12h 20m

Santiago Arturo Merino Benitez

Tue 10/14

11:00 am-6:35 pm

Nonstop8h 35m

$575

MiamiSantiago

MIA - SCL

MIASCL

Miami

Sun 9/28

1:40 am-3:00 pm

1 stop12h 20m

Santiago Arturo Merino Benitez

Mon 10/13

10:55 pm-6:30 am

Nonstop8h 35m

$575

MiamiSantiago

MIA - SCL

MIASCL

Miami

Sun 9/28

1:40 am-3:00 pm

1 stop12h 20m

Santiago Arturo Merino Benitez

Wed 10/8

10:55 pm-6:30 am

Nonstop8h 35m

$575

MiamiSantiago

MIA - SCL

MIASCL

Miami

Mon 10/20

1:40 am-2:25 pm

1 stop11h 45m

Santiago Arturo Merino Benitez

Thu 10/30

6:30 pm-7:10 am

1 stop13h 40m

$575

MiamiSantiago

MIA - SCL

MIASCL

Miami

Mon 11/3

8:45 pm-7:00 am

Nonstop8h 15m

Santiago Arturo Merino Benitez

Tue 11/25

11:25 pm-5:50 am

Nonstop8h 25m

$575

MiamiSantiago

MIA - SCL

MIASCL

Miami

Tue 9/30

9:20 pm-6:30 am

Nonstop8h 10m

Santiago Arturo Merino Benitez

Wed 10/15

11:00 am-6:35 pm

Nonstop8h 35m

$575

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 22 results
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Best time to book a flight from Florida Keys to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Santiago
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 17, 2025.
See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Florida Keys to Santiago have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Copa Airlines
7.6
Good
1,533 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
LATAM Airlines
7.5
Good
1,849 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Avianca
6.7
Okay
2,436 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Florida Keys?

    For a flight from Florida Keys to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city.

  • How long is the flight from Florida Keys to Santiago?

    Delta can get you from Florida Keys to Santiago in just under 15h 50m. Your travel time can differ by up to . Airlines will cover a distance of 4134 mi.

  • Can I find deals for flights from Florida Keys to Santiago that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Santiago.

  • Can I find deals for business class flights from Florida Keys to Santiago?

    Yes. Cheapflights offers flight deals from Florida Keys to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Florida Keys to Santiago (average of $752). Flying from Florida Keys to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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