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$295+ Cheap flights from Cancún (CUN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel.
CUN — SCL
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
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Cheap flight deals from Cancún to Santiago

Cheapest flights from Cancún to Santiago
Explore the most affordable flight options available from Cancún to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Arajet deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:32 pm
CUN
-
SCL
1 stop12h 23m
Arajet
Wed 9/304:35 am
SCL
-
CUN
1 stop12h 59m
Arajet
Deal found 3/16$551
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:35 pm
CUN
-
SCL
1 stop13h 00m
Multiple Airlines
Fri 6/56:45 pm
SCL
-
CUN
1 stop20h 35m
Multiple Airlines
Deal found 3/16$554
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:49 am
CUN
-
SCL
1 stop9h 54m
Copa Airlines
Wed 5/612:38 am
SCL
-
CUN
1 stop10h 55m
Copa Airlines
Deal found 3/15$614
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:45 pm
CUN
-
SCL
2 stops14h 19m
LATAM Airlines
Wed 5/205:40 am
SCL
-
CUN
1 stop11h 35m
LATAM Airlines
Deal found 3/16$631
This FlightHub deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:45 pm
CUN
-
SCL
1 stop10h 00m
LATAM Airlines
Thu 6/49:25 pm
SCL
-
CUN
1 stop21h 15m
LATAM Airlines
Deal found 3/14$633
This CheapOair deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/172:32 pm
CUN
-
SCL
1 stop28h 43m
Multiple Airlines
Tue 3/315:55 am
SCL
-
CUN
1 stop12h 00m
Multiple Airlines
Deal found 3/13$637
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:15 am
CUN
-
SCL
2 stops18h 35m
LATAM Airlines
Fri 6/59:13 pm
SCL
-
CUN
2 stops18h 07m
LATAM Airlines
Deal found 3/16$643
This Gotogate deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:35 pm
CUN
-
SCL
1 stop13h 00m
Multiple Airlines
Thu 5/73:24 pm
SCL
-
CUN
2 stops25h 51m
Multiple Airlines
Deal found 3/15$653
This Copa Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:01 am
CUN
-
SCL
1 stop18h 57m
Copa Airlines
Tue 4/284:17 am
SCL
-
CUN
1 stop12h 18m
Copa Airlines
Deal found 3/12$657

Find flight deals from Cancún to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cancún (CUN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$551
(Arajet)

One-way from

$295
(Super.com)

Popular in

January

Cheapest in

September

Average price

$669
Provider with most accurate pricing for Cancun-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cancun-Santiago Arturo Merino Benitez flights.
Search Deals
From Cancun to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Cancun to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($95 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cancún to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Cancún to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Sun 9/13

2:32 pm-4:55 am

1 stop12h 23m

Santiago Arturo Merino Benitez

Wed 9/30

4:35 am-3:34 pm

1 stop12h 59m

$551
Quickest round-trip

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 4/23

7:04 am-7:23 pm

1 stop11h 19m

Santiago Arturo Merino Benitez

Wed 5/6

12:38 am-10:33 am

1 stop10h 55m

$657

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Sat 3/28

11:45 am-12:34 am

1 stop10h 49m

Santiago Arturo Merino Benitez

Sat 4/11

4:49 am-3:35 pm

1 stop11h 46m

$657

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 4/2

2:03 pm-6:10 am

1 stop14h 07m

Santiago Arturo Merino Benitez

Mon 4/13

11:25 am-10:00 pm

1 stop11h 35m

$657

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 7/7

7:01 am-5:03 am

1 stop21h 02m

Santiago Arturo Merino Benitez

Mon 7/20

2:56 am-3:37 pm

1 stop13h 41m

$678

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Sun 4/5

2:32 pm-3:55 am

1 stop12h 23m

Santiago Arturo Merino Benitez

Fri 4/10

6:00 am-11:35 am

1 stop30h 35m

$682

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Fri 4/3

11:49 am-3:20 am

1 stop13h 31m

Santiago Arturo Merino Benitez

Fri 4/17

11:25 am-10:00 pm

1 stop11h 35m

$725
Cheapest one-way

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 6/11

12:35 pm-2:35 am

1 stop13h 00m

$295
Quickest one-way

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Wed 5/20

5:25 pm-5:25 am

1 stop11h 00m

$311

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 4/16

8:06 am-5:25 am

2 stops20h 19m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/16

Showing 1-10 of 13 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Cancún-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cancún-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cancún-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cancún-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cancún-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cancún to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cancún with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cancún to Santiago

How far ahead should I book a flight from Cancún to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Cancún to Santiago. Price data was last updated on March 13, 2026.

To ensure you get the cheapest price possible for a flight from Cancún to Santiago, you should look to book at least 17 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cancún to Santiago?

Currently, April is the cheapest month in which you can book a flight from Cancún to Santiago (average of $245). Flying from Cancún to Santiago in January is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CUN to SCL?

Find hourly flight availability from Cancún to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 17, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Cancún to Santiago as you normally would.

How much does it cost to fly round-trip from Cancún to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 17, 2026.
Read through reviews of airlines operating flights from Cancún to Santiago, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,917 reviews

Overall

7.4

Comfort

7.3

Boarding

7.5

Crew

8.0

Entertainment

7.0

Food

6.7

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
LATAM Airlines
7.4
Good
1,917 reviews
LATAM Airlines
7.4
Good
1,917 reviews

Overall

7.4

Comfort

7.3

Boarding

7.5

Crew

8.0

Entertainment

7.0

Food

6.7

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

Find useful and relevant information for your journey from Cancún to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cancún to Santiago?

    Arajet and Copa Airlines can get you from Cancún to Santiago in just under 11h 19m. Your travel time can differ by up to 1h 04m. There are 3905 mi between Cancún and Santiago. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Cancún to Santiago round-trip?

    Our cheapest airline available from Cancún to Santiago is LATAM Airlines. Our recent data shows that you can find tickets from as low as $608 on this airline.

  • What are the cheapest airlines to fly from Cancún to Santiago one-way?

    For one-way options, check prices for Sky Airline. According to our data, you can fly for as low as $201. Users have also found prices from $272 and $338 on Avianca and Copa Airlines, respectively.

  • Can I find deals for flights from Cancún to Santiago that include hotel bookings?

    Yes. In addition to deals on Cancún to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cancún to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cancún to Santiago.

  • Can I find deals for business class flights from Cancún to Santiago?

    Yes. Cheapflights offers flight deals from Cancún to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cancún to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Cancún to Santiago (average of $245). Flying from Cancún to Santiago in January is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Lastarria car rentals

Top airline flying from Cancún to Santiago

Discover the top airline that operate flights from Cancún to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$608Average$849FlexibilityNo cancel feeOn-time81%

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