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$257+ Cheap flights from Cancún (CUN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
CUN — SCL
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheapflights Tip: The best prices from Cancun to Santiago Arturo Merino Benitez are usually found in September or November, booked 79 days in advance, depart on a Monday or Tuesday and return on a Tuesday

Cheap flight deals from Cancún to Santiago

Cheapest flights from Cancún to Santiago
Explore the most affordable flight options available from Cancún to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This CheapOair deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2111:55 amCUN - SCL
1 stop15h 00mArajet
Fri 12/2612:40 amSCL - CUN
1 stop13h 20mArajet
Deal found 12/13$745
This Copa Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:50 amCUN - SCL
1 stop10h 34mCopa Airlines
Tue 1/1312:28 pmSCL - CUN
1 stop11h 33mCopa Airlines
Deal found 12/14$892
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:41 pmCUN - SCL
1 stop11h 20mCopa Airlines
Tue 1/1312:28 pmSCL - CUN
1 stop11h 33mCopa Airlines
Deal found 12/15$909
This CheapOair deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2112:35 pmCUN - SCL
1 stop24h 45mMultiple Airlines
Fri 12/261:35 amSCL - CUN
2 stops16h 20mMultiple Airlines
Deal found 12/13$1,048
This LATAM Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2112:15 pmCUN - SCL
Nonstop7h 45mLATAM Airlines
Sat 12/2710:22 pmSCL - CUN
1 stop17h 58mLATAM Airlines
Deal found 12/13$1,765

Find flight deals from Cancún to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cancún (CUN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$581
(CheapOair)

One-way from

$257
(Sky Airline)

Popular in

January

Cheapest in

September

Average price

$565

Good one-way deal

$408 or less
Provider with most accurate pricing for Cancun-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cancun-Santiago Arturo Merino Benitez flights.
Search Deals
From Cancun to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Cancun to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($88 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a one-way flight from Cancun to Santiago Arturo Merino Benitez.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cancún to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Cancún to Santiago that are best for you.

Fly from

Cancún

Fly to

Santiago

Route

Depart

Return

Price

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Fri 3/13

12:35 pm-5:30 am

1 stop14h 55m

Santiago Arturo Merino Benitez

Fri 3/20

6:00 am-4:49 pm

1 stop12h 49m

$559

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 2/5

4:55 pm-2:40 pm

1 stop19h 45m

Santiago Arturo Merino Benitez

Thu 3/5

5:50 am-3:55 pm

1 stop12h 05m

$604

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 2/5

6:25 pm-3:20 pm

1 stop18h 55m

Santiago Arturo Merino Benitez

Thu 3/5

9:05 pm-3:55 pm

1 stop20h 50m

$627

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 2/5

12:35 pm-3:35 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Mon 2/9

6:00 am-4:57 pm

1 stop12h 57m

$698

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Fri 3/13

12:15 pm-10:00 pm

Nonstop7h 45m

Santiago Arturo Merino Benitez

Fri 3/20

9:30 am-3:40 pm

Nonstop8h 10m

$700

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 12/23

4:55 pm-2:40 pm

1 stop19h 45m

$257

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Sun 1/11

4:55 pm-12:15 pm

2 stops17h 20m

$262

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Fri 1/9

4:55 pm-6:40 am

1 stop11h 45m

$278

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 1/13

2:00 pm-4:00 am

1 stop12h 00m

$312

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Wed 4/1

12:45 pm-5:15 am

1 stop14h 30m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 11 results
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Compare providers for flights from Cancún to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cancún to Santiago in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Cancún-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Cancún-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Cancún-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cancún-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cancún-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cancún to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cancún with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cancún to Santiago

How far ahead should I book a flight from Cancún to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Cancún to Santiago. Price data was last updated on December 12, 2025.

To ensure you get the cheapest price possible for a flight from Cancún to Santiago, you should look to book at least 77 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cancún to Santiago?

Currently, April is the cheapest month in which you can book a flight from Cancún to Santiago (average of $242). Flying from Cancún to Santiago in January is currently the most expensive (average of $504). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CUN to SCL?

Find hourly flight availability from Cancún to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

When flying from Cancún to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 53% versus a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Cancún to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cancún to Santiago?

    Sky Airline can get you from Cancún to Santiago in just under 19h 45m. Your travel time can differ by up to . There are 3905 mi between Cancún and Santiago.

  • What are the cheapest airlines to fly from Cancún to Santiago one-way?

    For one-way options, check prices for Sky Airline. According to our data, you can fly for as low as $201. Users have also found prices from $240 and $342 on Avianca and Copa Airlines, respectively.

  • What are the cheapest flights from Cancún to Santiago?

    The cheapest flight price from Cancún to Santiago is $408. On average you can expect to pay $522. The most popular route, (Cancun - Santiago Arturo Merino Benitez), can usually be booked for $627.

  • Can I find deals for flights from Cancún to Santiago that include hotel bookings?

    Yes. In addition to deals on Cancún to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cancún to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cancún to Santiago.

  • Can I find deals for business class flights from Cancún to Santiago?

    Yes. Cheapflights offers flight deals from Cancún to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cancún to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Cancún to Santiago (average of $242). Flying from Cancún to Santiago in January is currently the most expensive (average of $504). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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