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$249+ Cheap flights from Cancún (CUN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
CUN — SCL
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheapflights Tip: The best prices from Cancun to Santiago Arturo Merino Benitez are usually found in September or August, booked 75 days in advance, depart on a Monday or Tuesday and return on a Tuesday

Cheap flight deals from Cancún to Santiago

Cheapest flights from Cancún to Santiago
Explore the most affordable flight options available from Cancún to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This LATAM Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:45 pm
CUN
-
SCL
1 stop17h 20m
LATAM Airlines
Sat 4/259:10 pm
SCL
-
CUN
1 stop20h 05m
LATAM Airlines
Deal found 1/27$482
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:25 pm
CUN
-
SCL
1 stop33h 05m
Avianca
Thu 3/191:35 am
SCL
-
CUN
1 stop17h 50m
Avianca
Deal found 1/27$504
This Travelocity deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:25 pm
CUN
-
SCL
1 stop33h 05m
Multiple Airlines
Fri 3/206:00 am
SCL
-
CUN
1 stop12h 49m
Multiple Airlines
Deal found 1/27$511
This Arajet deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/512:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Mon 3/96:00 am
SCL
-
CUN
1 stop12h 57m
Arajet
Deal found 1/26$532
This Booking.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/512:35 pm
CUN
-
SCL
1 stop13h 00m
Multiple Airlines
Sun 3/85:50 am
SCL
-
CUN
1 stop12h 05m
Multiple Airlines
Deal found 1/27$538
This Arajet deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Mon 9/286:00 am
SCL
-
CUN
1 stop12h 57m
Arajet
Deal found 1/27$540
This Orbitz deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:25 pm
CUN
-
SCL
2 stops17h 14m
Multiple Airlines
Sat 4/2511:55 pm
SCL
-
CUN
1 stop15h 45m
Multiple Airlines
Deal found 1/27$553
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/54:55 pm
CUN
-
SCL
2 stops17h 05m
Sky Airline
Sat 3/71:35 am
SCL
-
CUN
2 stops16h 20m
Sky Airline
Deal found 1/27$558
This Arajet deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Mon 11/26:00 am
SCL
-
CUN
1 stop12h 57m
Arajet
Deal found 1/25$567
This FlightHub deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/34:55 pm
CUN
-
SCL
2 stops17h 05m
Sky Airline
Mon 3/91:35 am
SCL
-
CUN
2 stops16h 20m
Sky Airline
Deal found 1/27$570

Find flight deals from Cancún to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cancún (CUN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$482
(LATAM Airlines)

One-way from

$249
(FlightHub)

Popular in

January

Cheapest in

September

Average price

$739

Good round-trip deal

$840 or less

Good one-way deal

$368 or less
Provider with most accurate pricing for Cancun-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cancun-Santiago Arturo Merino Benitez flights.
Search Deals
From Cancun to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Cancun to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($91 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Cancun to Santiago Arturo Merino Benitez.
Search Deals
Price to beat on a one-way flight from Cancun to Santiago Arturo Merino Benitez.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cancún to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Cancún to Santiago that are best for you.

Fly from

Cancún

Fly to

Santiago

Route

Depart

Return

Price

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Fri 4/17

6:45 pm-1:05 pm

1 stop17h 20m

Santiago Arturo Merino Benitez

Sat 4/25

9:10 pm-4:15 pm

1 stop20h 05m

$482

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Fri 3/13

6:25 pm-5:30 am

1 stop33h 05m

Santiago Arturo Merino Benitez

Thu 3/19

1:35 am-5:25 pm

1 stop17h 50m

$504

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 3/5

12:35 pm-3:35 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Mon 3/9

6:00 am-4:57 pm

1 stop12h 57m

$532

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 3/5

12:35 pm-3:35 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Sun 3/8

5:50 am-3:55 pm

1 stop12h 05m

$538

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Fri 3/13

6:25 pm-5:30 am

1 stop33h 05m

Santiago Arturo Merino Benitez

Fri 3/20

9:30 am-3:40 pm

Nonstop8h 10m

$539

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 3/5

4:55 pm-12:00 pm

2 stops17h 05m

Santiago Arturo Merino Benitez

Sat 3/7

1:35 am-3:55 pm

2 stops16h 20m

$558

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 3/3

4:55 pm-12:00 pm

2 stops17h 05m

Santiago Arturo Merino Benitez

Mon 3/9

1:35 am-3:55 pm

2 stops16h 20m

$570

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Wed 4/1

4:50 pm-3:15 pm

1 stop20h 25m

$249

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Sun 3/22

11:55 am-4:55 am

1 stop15h 00m

$250

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Wed 4/1

3:25 pm-6:25 am

1 stop13h 00m

$270

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 17 results
1
2
  • Most accurate provider: When it comes to deals on Cancún-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cancún-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cancún-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cancún-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cancún-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cancún to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cancún with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cancún to Santiago

How far ahead should I book a flight from Cancún to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Cancún to Santiago. Price data was last updated on January 23, 2026.

To ensure you get the cheapest price possible for a flight from Cancún to Santiago, you should look to book at least 75 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cancún to Santiago?

Currently, April is the cheapest month in which you can book a flight from Cancún to Santiago (average of $242). Flying from Cancún to Santiago in July is currently the most expensive (average of $449). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CUN to SCL?

Find hourly flight availability from Cancún to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 28, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Cancún to Santiago as you normally would.

How much does it cost to fly round-trip from Cancún to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 28, 2026.
Read through reviews of airlines operating flights from Cancún to Santiago, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,915 reviews

Boarding

7.5

Food

6.7

Overall

7.5

Comfort

7.3

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
LATAM Airlines
7.5
Good
1,915 reviews
LATAM Airlines
7.5
Good
1,915 reviews

Boarding

7.5

Food

6.7

Overall

7.5

Comfort

7.3

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken

Related info for your journey

Find useful and relevant information for your journey from Cancún to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cancún to Santiago?

    LATAM Airlines, Avianca, and Arajet can get you from Cancún to Santiago in just under 13h. Your travel time can differ by up to 20h 05m. There are 3905 mi between Cancún and Santiago. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Cancún to Santiago round-trip?

    Our cheapest airline available from Cancún to Santiago is LATAM Airlines. Our recent data shows that you can find tickets from as low as $576 on this airline.

  • What are the cheapest airlines to fly from Cancún to Santiago one-way?

    For one-way options, check prices for Sky Airline. According to our data, you can fly for as low as $201. Users have also found prices from $244 and $342 on Avianca and Copa Airlines, respectively.

  • What are the cheapest flights from Cancún to Santiago?

    The cheapest flight price from Cancún to Santiago is $351. On average you can expect to pay $617. The most popular route, (Cancun - Santiago Arturo Merino Benitez), can usually be booked for $509.

  • Can I find deals for flights from Cancún to Santiago that include hotel bookings?

    Yes. In addition to deals on Cancún to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cancún to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cancún to Santiago.

  • Can I find deals for business class flights from Cancún to Santiago?

    Yes. Cheapflights offers flight deals from Cancún to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cancún to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Cancún to Santiago (average of $242). Flying from Cancún to Santiago in July is currently the most expensive (average of $449). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Lastarria car rentals

Top airline flying from Cancún to Santiago

Discover the top airline that operate flights from Cancún to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$576Average$849FlexibilityNo cancel feeOn-time81%

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