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$216+ Cheap flights from Cancún (CUN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
CUN — SCL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Cancun to Santiago Arturo Merino Benitez are usually found in September or November, booked 53 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from Cancún to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cancún (CUN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$402
(Arajet)

One-way from

$216
(Arajet)

Popular in

January

Cheapest in

September

Average price

$468
From Cancun to Santiago Arturo Merino Benitez
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One-way flight from Cancun to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 18% potential increase in price ($124 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Cancún to Santiago

Cheapest flights from Cancún to Santiago
Explore the most affordable flight options available from Cancún to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Arajet deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/212:35 pmCUN - SCL
1 stop13h 00mArajet
Fri 10/104:35 amSCL - CUN
1 stop12h 55mArajet
Deal found 9/9$402
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1911:55 amCUN - SCL
1 stop13h 40mArajet
Fri 10/244:35 amSCL - CUN
1 stop12h 55mArajet
Deal found 9/9$420
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/75:00 pmCUN - SCL
1 stop27h 15mSky Airline
Tue 10/145:55 amSCL - CUN
1 stop11h 55mSky Airline
Deal found 9/10$448
This Sky Airline deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/165:00 pmCUN - SCL
1 stop19h 45mSky Airline
Thu 10/25:55 amSCL - CUN
1 stop11h 55mSky Airline
Deal found 9/11$457
This Arajet deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/412:35 pmCUN - SCL
1 stop13h 00mArajet
Mon 11/106:00 amSCL - CUN
1 stop12h 57mArajet
Deal found 9/9$472
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/304:55 pmCUN - SCL
2 stops17h 20mMultiple Airlines
Thu 11/206:40 amSCL - CUN
1 stop11h 35mMultiple Airlines
Deal found 9/10$495
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/75:00 pmCUN - SCL
1 stop19h 45mMultiple Airlines
Mon 10/1312:55 amSCL - CUN
1 stop15h 45mMultiple Airlines
Deal found 9/10$518
This OneTravel deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:55 pmCUN - SCL
1 stop14h 30mMultiple Airlines
Fri 10/319:05 pmSCL - CUN
1 stop20h 45mMultiple Airlines
Deal found 9/9$550

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cancún to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Cancún to Santiago that are best for you.

Fly from

Cancún

Fly to

Santiago

Route

Depart

Return

Price

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 10/2

12:35 pm-3:35 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Fri 10/10

4:35 am-3:30 pm

1 stop12h 55m

$402

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Sun 10/19

11:55 am-3:35 am

1 stop13h 40m

Santiago Arturo Merino Benitez

Fri 10/24

4:35 am-3:30 pm

1 stop12h 55m

$420

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 10/30

4:55 pm-12:15 pm

2 stops17h 20m

Santiago Arturo Merino Benitez

Wed 11/19

1:30 am-3:50 pm

2 stops16h 20m

$448

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 10/7

5:00 pm-6:00 am

1 stop11h 00m

Santiago Arturo Merino Benitez

Mon 10/13

1:45 am-3:50 pm

2 stops16h 05m

$448

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 9/16

5:00 pm-2:45 pm

1 stop19h 45m

Santiago Arturo Merino Benitez

Thu 10/2

5:55 am-3:50 pm

1 stop11h 55m

$457

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 11/4

12:35 pm-3:35 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Mon 11/10

6:00 am-4:57 pm

1 stop12h 57m

$472

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 10/30

4:55 pm-12:15 pm

2 stops17h 20m

Santiago Arturo Merino Benitez

Thu 11/20

6:40 am-4:15 pm

1 stop11h 35m

$495

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 10/7

5:00 pm-2:45 pm

1 stop19h 45m

Santiago Arturo Merino Benitez

Mon 10/13

12:55 am-2:40 pm

1 stop15h 45m

$518

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Fri 10/24

9:55 pm-2:25 pm

1 stop14h 30m

Santiago Arturo Merino Benitez

Fri 10/31

9:05 pm-3:50 pm

1 stop20h 45m

$550

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 10/2

12:35 pm-3:35 am

1 stop13h 00m

$216

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 15 results
1
2

Best time to book a flight from Cancún to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cancún with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cancún to Santiago

How far ahead should I book a flight from Cancún to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Cancún to Santiago. Price data was last updated on August 29, 2025.

To ensure you get the cheapest price possible for a flight from Cancún to Santiago, you should look to book at least 53 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cancún to Santiago?

Currently, April is the cheapest month in which you can book a flight from Cancún to Santiago (average of $752). Flying from Cancún to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CUN to SCL?

Find hourly flight availability from Cancún to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Cancún to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 10% versus a flight in the morning.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Cancún to Santiago, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Entertainment

6.8

Overall

7.6

Food

6.8

Crew

8.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Entertainment

6.8

Overall

7.6

Food

6.8

Crew

8.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Cancún to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cancún to Santiago?

    Arajet and Sky Airline can get you from Cancún to Santiago in just under 13h. Your travel time can differ by up to 4h 20m. There are 3905 mi between Cancún and Santiago. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Cancún to Santiago round-trip?

    Our cheapest airline available from Cancún to Santiago is Copa Airlines. Our recent data shows that you can find tickets from as low as $394 on this airline. You may be able to fly from Cancún to Santiago for 28% less than the average price by searching for this airline.

  • Can I find deals for flights from Cancún to Santiago that include hotel bookings?

    Yes. In addition to deals on Cancún to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cancún to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cancún to Santiago.

  • Can I find deals for business class flights from Cancún to Santiago?

    Yes. Cheapflights offers flight deals from Cancún to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cancún to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Cancún to Santiago (average of $752). Flying from Cancún to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
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Temuco car rentals
Lastarria car rentals

Top airline flying from Cancún to Santiago

Discover the top airline that operate flights from Cancún to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$394Average$723FlexibilityNo cancel feeOn-time70%

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