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$364+ Cheap flights from Portland, ME to Santa Fe (PWM - SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SAF
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
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Cheap flight deals from Portland to Santa Fe

Cheapest flights from Portland to Santa Fe
Explore the most affordable flight options available from Portland to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:01 am
PWM
-
SAF
2 stops12h 00m
American Airlines
Mon 9/146:45 am
SAF
-
PWM
2 stops11h 38m
American Airlines
Deal found 4/29$414
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:00 am
PWM
-
SAF
2 stops11h 21m
American Airlines
Tue 10/278:40 am
SAF
-
PWM
2 stops9h 34m
American Airlines
Deal found 4/28$479
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:30 pm
PWM
-
SAF
2 stops10h 04m
American Airlines
Thu 8/206:49 am
SAF
-
PWM
1 stop8h 43m
American Airlines
Deal found 4/27$522

Find flight deals from Portland to Santa Fe

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Santa Fe (SAF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$414
(American Airlines)

One-way from

$364
(American Airlines)

Popular in

June

Cheapest in

July
Provider with most accurate pricing for Portland-Santa Fe flight deals.
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Provider most trusted by Cheapflights users for Portland-Santa Fe flights.
Search Deals
From Portland to Santa Fe
Search Deals
One-way flight from Portland to Santa Fe
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Portland to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Fri 10/23

7:00 am-4:21 pm

2 stops11h 21m

Santa Fe

Tue 10/27

8:40 am-8:14 pm

2 stops9h 34m

$479

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Thu 9/10

12:25 pm-8:32 pm

1 stop10h 07m

Santa Fe

Mon 9/14

6:45 am-8:23 pm

2 stops11h 38m

$481

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Mon 8/17

1:30 pm-9:34 pm

2 stops10h 04m

Santa Fe

Thu 8/20

6:49 am-5:32 pm

1 stop8h 43m

$522
Quickest round-trip

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Thu 6/11

3:05 pm-10:34 pm

2 stops9h 29m

Santa Fe

Wed 6/17

6:05 am-4:37 pm

2 stops8h 32m

$614

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Wed 10/14

8:01 am-7:03 pm

2 stops13h 02m

Santa Fe

Mon 10/19

2:33 pm-11:33 am

1 stop19h 00m

$615

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Thu 6/11

7:58 am-6:48 pm

2 stops12h 50m

Santa Fe

Mon 6/15

6:55 am-12:42 am

1 stop15h 47m

$656
Cheapest one-way

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Fri 5/15

7:10 am-5:56 pm

2 stops12h 46m

$364
Quickest one-way

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Fri 5/15

3:23 pm-8:28 pm

1 stop7h 05m

$490

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Sat 8/1

8:00 am-4:53 pm

2 stops10h 53m

$555

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Sat 8/1

7:16 pm-2:44 pm

3 stops21h 28m

$1,276

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Portland, Maine-Santa Fe flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Portland, Maine-Santa Fe flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Portland, Maine-Santa Fe flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Santa Fe flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Santa Fe flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santa Fe

How much does it cost to fly round-trip from Portland, Maine to Santa Fe?

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated April 30, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Portland to Santa Fe by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,677 reviews

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
United Airlines
7.4
Good
9,677 reviews
United Airlines
7.4
Good
9,677 reviews

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
American Airlines
7.1
Good
11,681 reviews
United Airlines
7.4
Good
9,677 reviews

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Related info for your journey

Find useful and relevant information for your journey from Portland to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Santa Fe?

    Departing from Portland, Maine to Santa Fe will take you 11h 21m. The distance between Portland, Maine and Santa Fe is about 1965 mi.

  • What are the cheapest airlines flying from Portland, Maine to Santa Fe round-trip?

    Our cheapest airline available from Portland, Maine to Santa Fe is American Airlines. Our recent data shows that you can find tickets from as low as $344 on this airline. An additional option worth looking into is United Airlines, starting at $399. Users have found that American Airlines is 33% cheaper than the other options available to this destination.

  • Can I find deals for flights from Portland to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Portland to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santa Fe.

  • Can I find deals for business class flights from Portland to Santa Fe?

    Yes. Cheapflights offers flight deals from Portland to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Alternative routes for Portland to Santa Fe

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Portland to Santa Fe

Discover the top 2 airlines that operate flights from Portland to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$344Average$498FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$399Average$594FlexibilityNo cancel feeOn-time69%

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