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$379+ Cheap flights from Portland, ME to Santa Fe (PWM - SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SAF
Sep 9 — Sep 161
Wed 9/9
Wed 9/16
1 adult, Economy
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Cheap flight deals from Portland to Santa Fe

Cheapest flights from Portland to Santa Fe
Explore the most affordable flight options available from Portland to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.

This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:00 am -
1 stop7h 38m
Wed 9/96:47 am -
1 stop8h 07m
Deal found 8/6$389
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:03 pm -
1 stop9h 54m
Mon 9/148:00 am -
1 stop8h 46m
Deal found 8/7$434
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:30 pm -
2 stops10h 28m
Tue 8/257:10 am -
2 stops13h 38m
Deal found 8/6$439
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:00 am -
1 stop7h 38m
Tue 9/88:40 am -
2 stops10h 41m
Deal found 8/6$511

Find flight deals from Portland to Santa Fe

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Santa Fe (SAF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$389
(American Airlines)

One-way from

$379
(American Airlines)

Popular in

June

Cheapest in

March

Average price

$802
Provider with most accurate pricing for Portland-Santa Fe flight deals.
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Provider most trusted by Cheapflights users for Portland-Santa Fe flights.
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From Portland to Santa Fe
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One-way flight from Portland to Santa Fe
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($144 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($64 potential savings vs. average RT price).
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Average for round-trip flights in August 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Portland to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandSanta Fe

PWM Portland - SAF Santa Fe

PWMSAF

Portland

Wed 8/26

5:30 am-3:05 pm

2 stops11h 35m

Santa Fe

Wed 9/9

8:00 am-11:47 pm

2 stops13h 47m

$439

PortlandSanta Fe

PWM Portland - SAF Santa Fe

PWMSAF

Portland

Thu 9/10

2:03 pm-9:57 pm

1 stop9h 54m

Santa Fe

Mon 9/14

10:16 am-11:36 pm

2 stops11h 20m

$495

PortlandSanta Fe

PWM Portland - SAF Santa Fe

PWMSAF

Portland

Fri 8/21

6:03 am-5:11 pm

2 stops13h 08m

Santa Fe

Tue 8/25

1:22 pm-11:59 pm

2 stops8h 37m

$565
Quickest round-trip

PortlandSanta Fe

PWM Portland - SAF Santa Fe

PWMSAF

Portland

Fri 11/13

3:23 pm-8:29 pm

1 stop7h 06m

Santa Fe

Mon 11/16

7:00 am-4:02 pm

1 stop7h 02m

$575

PortlandSanta Fe

PWM Portland - SAF Santa Fe

PWMSAF

Portland

Fri 11/13

8:47 am-5:10 pm

2 stops10h 23m

Santa Fe

Tue 11/17

7:00 am-4:02 pm

1 stop7h 02m

$613

PortlandSanta Fe

PWM Portland - SAF Santa Fe

PWMSAF

Portland

Thu 11/12

3:23 pm-9:45 am

1 stop20h 22m

Santa Fe

Tue 11/17

9:47 am-11:21 pm

2 stops11h 34m

$613

PortlandSanta Fe

PWM Portland - SAF Santa Fe

PWMSAF

Portland

Sat 1/9

9:45 am-5:06 pm

2 stops9h 21m

Santa Fe

Wed 1/13

7:00 am-10:57 pm

2 stops13h 57m

$629

PortlandSanta Fe

PWM Portland - SAF Santa Fe

PWMSAF

Portland

Wed 10/14

11:27 am-9:55 pm

2 stops12h 28m

Santa Fe

Mon 10/19

1:29 pm-11:40 pm

1 stop8h 11m

$640
Cheapest one-way

PortlandSanta Fe

PWM Portland - SAF Santa Fe

PWMSAF

Portland

Fri 9/18

10:47 am-9:37 pm

2 stops12h 50m

$384
Quickest one-way

PortlandSanta Fe

PWM Portland - SAF Santa Fe

PWMSAF

Portland

Fri 8/21

8:00 am-1:38 pm

1 stop7h 38m

$459

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/6

Showing 1-10 of 13 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Portland, Maine-Santa Fe flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Portland, Maine-Santa Fe flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Portland, Maine-Santa Fe flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Santa Fe flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Santa Fe flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated August 10, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Portland to Santa Fe by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
10,095 reviews

Entertainment

7.1

Food

6.7

Overall

7.4

Boarding

7.7

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Dawn,Aug 2026

ORD - DEN

I missed my connecting flight because our plane took off ten minutes late and then when we got to the airport another plane was in our shoot waiting to get fueled up and that took 30 minutes so I missed my connecting flight. I asked if I could get off and they assured me the plane would most likely wait for me since they know what time the planes get in because of an app. I was not happy. I had to wait till 7:25 to board the next flight and then that was delayed. Gates changed till 9:20. Terrible
United Airlines
7.4
Good
10,095 reviews
United Airlines
7.4
Good
10,095 reviews

Entertainment

7.1

Food

6.7

Overall

7.4

Boarding

7.7

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Dawn,Aug 2026

ORD - DEN

I missed my connecting flight because our plane took off ten minutes late and then when we got to the airport another plane was in our shoot waiting to get fueled up and that took 30 minutes so I missed my connecting flight. I asked if I could get off and they assured me the plane would most likely wait for me since they know what time the planes get in because of an app. I was not happy. I had to wait till 7:25 to board the next flight and then that was delayed. Gates changed till 9:20. Terrible
American Airlines
7.1
Good
11,897 reviews
United Airlines
7.4
Good
10,095 reviews

Entertainment

7.1

Food

6.7

Overall

7.4

Boarding

7.7

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Dawn,Aug 2026

ORD - DEN

I missed my connecting flight because our plane took off ten minutes late and then when we got to the airport another plane was in our shoot waiting to get fueled up and that took 30 minutes so I missed my connecting flight. I asked if I could get off and they assured me the plane would most likely wait for me since they know what time the planes get in because of an app. I was not happy. I had to wait till 7:25 to board the next flight and then that was delayed. Gates changed till 9:20. Terrible

Related info for your journey

Find useful and relevant information for your journey from Portland to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Santa Fe?

    Departing from Portland, Maine to Santa Fe will take you 11h 35m. The distance between Portland, Maine and Santa Fe is about 1965 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Portland, Maine to Santa Fe round-trip?

    Our cheapest airline available from Portland, Maine to Santa Fe is United Airlines. Our recent data shows that you can find tickets from as low as $399 on this airline. An additional option worth looking into is American Airlines, starting at $428. Users have found that United Airlines is 41% cheaper than the other options available to this destination.

  • Can I find deals for flights from Portland to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Portland to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santa Fe.

  • Can I find deals for business class flights from Portland to Santa Fe?

    Yes. Cheapflights offers flight deals from Portland to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Portland to Santa Fe

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Portland to Santa Fe

Discover the top 2 airlines that operate flights from Portland to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$399Average$594FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$428Average$592FlexibilityNo cancel feeOn-time71%

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