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$394+ Cheap flights from Portland, ME to Santa Fe (PWM - SAF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SAF
feb. 26 — mar. 51
jue. 2/26
jue. 3/5
1 adult, Economy
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Cheap flight deals from Portland to Santa Fe

Cheapest flights from Portland to Santa Fe
Explore the most affordable flight options available from Portland to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/136:17 am
PWM
-
SAF
1 stop9h 47m
American Airlines
lun. 3/162:35 pm
SAF
-
PWM
1 stop6h 59m
American Airlines
Deal found 1/25$394
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/106:17 am
PWM
-
SAF
1 stop9h 45m
American Airlines
mar. 3/172:33 pm
SAF
-
PWM
1 stop7h 04m
American Airlines
Deal found 1/25$395
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/412:29 pm
PWM
-
SAF
2 stops10h 40m
American Airlines
mié. 3/112:33 pm
SAF
-
PWM
1 stop7h 01m
American Airlines
Deal found 1/25$404
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/105:20 am
PWM
-
SAF
2 stops13h 15m
American Airlines
sáb. 2/1410:09 am
SAF
-
PWM
2 stops10h 41m
American Airlines
Deal found 1/26$415
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/106:17 am
PWM
-
SAF
1 stop9h 45m
American Airlines
lun. 3/162:35 pm
SAF
-
PWM
1 stop6h 59m
American Airlines
Deal found 1/25$420
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/106:00 am
PWM
-
SAF
2 stops10h 02m
American Airlines
sáb. 3/142:35 pm
SAF
-
PWM
1 stop6h 59m
American Airlines
Deal found 1/25$429
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/136:17 am
PWM
-
SAF
1 stop9h 47m
American Airlines
jue. 3/262:35 pm
SAF
-
PWM
1 stop6h 59m
American Airlines
Deal found 1/25$445
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/85:42 am
PWM
-
SAF
2 stops10h 22m
American Airlines
sáb. 3/142:35 pm
SAF
-
PWM
1 stop6h 59m
American Airlines
Deal found 1/25$454
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/126:17 am
PWM
-
SAF
1 stop9h 47m
American Airlines
mié. 3/252:36 pm
SAF
-
PWM
1 stop6h 58m
American Airlines
Deal found 1/25$459
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/246:00 am
PWM
-
SAF
2 stops11h 45m
American Airlines
jue. 3/122:35 pm
SAF
-
PWM
1 stop6h 59m
American Airlines
Deal found 1/26$468
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/246:00 am
PWM
-
SAF
2 stops11h 45m
American Airlines
mar. 3/310:09 am
SAF
-
PWM
2 stops11h 41m
American Airlines
Deal found 1/25$469

Find flight deals from Portland to Santa Fe

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Santa Fe (SAF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 27, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$394
(American Airlines)

Popular in

February

Cheapest in

July

Average price

$346
Provider with most accurate pricing for Portland-Santa Fe flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Santa Fe flights.
Search Deals
From Portland to Santa Fe
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($48 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 27, 2026.
Use the filters below to find and compare flights from Portland to Santa Fe that are best for you.

Fly from

Portland

Fly to

Santa Fe

Route

Depart

Return

Price

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

mar. 3/10

6:17 am-2:02 pm

1 stop9h 45m

Santa Fe

sáb. 3/14

2:35 pm-11:34 pm

1 stop6h 59m

$420

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

dom. 5/24

1:31 pm-9:59 pm

2 stops10h 28m

Santa Fe

sáb. 5/30

7:05 pm-10:27 am

2 stops13h 22m

$498

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

mar. 2/24

6:00 am-5:08 pm

2 stops13h 08m

Santa Fe

mié. 3/11

5:53 pm-10:49 am

2 stops14h 56m

$534

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

mar. 2/24

6:00 am-2:45 pm

2 stops10h 45m

Santa Fe

mar. 3/10

5:53 pm-3:14 pm

2 stops19h 21m

$534

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

sáb. 2/28

5:57 pm-1:13 pm

2 stops21h 16m

Santa Fe

mié. 3/11

2:33 pm-11:34 pm

1 stop7h 01m

$539

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

sáb. 2/28

5:57 pm-1:13 pm

2 stops21h 16m

Santa Fe

lun. 3/9

2:35 pm-11:34 pm

1 stop6h 59m

$539

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

mié. 2/25

6:00 am-6:12 pm

2 stops14h 12m

Santa Fe

mar. 3/10

12:54 pm-11:55 pm

2 stops9h 01m

$559

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

lun. 3/2

5:40 pm-12:24 pm

2 stops20h 44m

Santa Fe

lun. 3/9

2:35 pm-11:34 pm

1 stop6h 59m

$595

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

mar. 3/10

6:00 am-2:02 pm

2 stops10h 02m

Santa Fe

mié. 3/25

12:54 pm-11:55 pm

2 stops9h 01m

$595

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

jue. 2/19

3:05 pm-9:24 am

2 stops20h 19m

Santa Fe

mar. 3/10

5:53 pm-10:49 am

2 stops14h 56m

$608

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 13 results
1
2
  • Most accurate provider: When it comes to deals on Portland, Maine-Santa Fe flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Portland, Maine-Santa Fe flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Portland, Maine-Santa Fe flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Santa Fe flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Santa Fe flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santa Fe

What is the cheapest month to book a flight from Portland, Maine to Santa Fe?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Santa Fe (average of $191). Flying from Portland, Maine to Santa Fe in March is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated enero 27, 2026.
Get a feel of what it's like to fly with American Airlines from Portland to Santa Fe by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,197 reviews

Entertainment

6.9

Crew

8.0

Food

6.4

Overall

7.2

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,197 reviews
American Airlines
7.2
Good
11,197 reviews

Entertainment

6.9

Crew

8.0

Food

6.4

Overall

7.2

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Portland to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Santa Fe?

    Departing from Portland, Maine to Santa Fe will take you 9h 45m. The distance between Portland, Maine and Santa Fe is about 1965 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Portland, Maine to Santa Fe round-trip?

    Our cheapest airline available from Portland, Maine to Santa Fe is American Airlines. Our recent data shows that you can find tickets from as low as $299 on this airline. Users have found that American Airlines is 41% cheaper than the other options available to this destination.

  • Can I find deals for flights from Portland to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Portland to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santa Fe.

  • Can I find deals for business class flights from Portland to Santa Fe?

    Yes. Cheapflights offers flight deals from Portland to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Santa Fe?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Santa Fe (average of $191). Flying from Portland, Maine to Santa Fe in March is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Top airline flying from Portland to Santa Fe

Discover the top airline that operate flights from Portland to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$299Average$424FlexibilityNo cancel feeOn-time71%

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