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$224+ Cheap flights from Portland, ME to Santa Fe (PWM - SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SAF
Apr 10 — Apr 171
Fri 4/10
Fri 4/17
1 adult, Economy
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Cheap flight deals from Portland to Santa Fe

Cheapest flights from Portland to Santa Fe
Explore the most affordable flight options available from Portland to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.

This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
PWM
-
SAF
2 stops10h 55m
American Airlines
Wed 4/156:30 pm
SAF
-
PWM
2 stops14h 45m
American Airlines
Deal found 3/9$393
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:07 am
PWM
-
SAF
2 stops12h 49m
American Airlines
Thu 5/146:30 pm
SAF
-
PWM
2 stops14h 45m
American Airlines
Deal found 3/9$444
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:35 pm
PWM
-
SAF
2 stops10h 17m
American Airlines
Tue 6/26:05 am
SAF
-
PWM
1 stop8h 41m
American Airlines
Deal found 3/11$448
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:14 am
PWM
-
SAF
1 stop8h 48m
American Airlines
Mon 10/196:15 am
SAF
-
PWM
1 stop8h 47m
American Airlines
Deal found 3/8$452
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:57 am
PWM
-
SAF
2 stops12h 55m
American Airlines
Sat 5/306:05 am
SAF
-
PWM
1 stop8h 41m
American Airlines
Deal found 3/9$459
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
PWM
-
SAF
2 stops13h 56m
American Airlines
Sat 5/96:30 pm
SAF
-
PWM
2 stops14h 45m
American Airlines
Deal found 3/11$468
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:00 am
PWM
-
SAF
2 stops10h 55m
American Airlines
Sun 5/246:05 am
SAF
-
PWM
1 stop8h 41m
American Airlines
Deal found 3/11$478
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
PWM
-
SAF
2 stops10h 46m
United Airlines
Tue 8/2510:30 am
SAF
-
PWM
2 stops11h 29m
United Airlines
Deal found 3/10$499

Find flight deals from Portland to Santa Fe

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Santa Fe (SAF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 11, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$393
(American Airlines)

One-way from

$224
(American Airlines)

Popular in

June

Cheapest in

July

Average price

$453
Provider with most accurate pricing for Portland-Santa Fe flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Santa Fe flights.
Search Deals
From Portland to Santa Fe
Search Deals
One-way flight from Portland to Santa Fe
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Portland to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Sun 5/24

10:57 am-9:52 pm

2 stops12h 55m

Santa Fe

Sat 5/30

7:30 am-4:46 pm

1 stop7h 16m

$515

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Sat 8/22

5:15 am-2:46 pm

2 stops11h 31m

Santa Fe

Tue 8/25

10:30 am-11:59 pm

2 stops11h 29m

$528

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Sun 5/24

5:15 am-5:12 pm

2 stops13h 57m

Santa Fe

Sat 5/30

3:19 pm-11:51 pm

2 stops30h 32m

$549

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Thu 5/21

7:15 am-6:48 pm

2 stops13h 33m

Santa Fe

Tue 6/2

7:30 am-4:46 pm

1 stop7h 16m

$654

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Wed 4/29

6:00 am-5:06 pm

2 stops13h 06m

Santa Fe

Sat 5/9

5:49 pm-3:41 pm

1 stop19h 52m

$668

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Fri 5/22

3:31 pm-9:44 am

1 stop20h 13m

Santa Fe

Tue 6/2

6:00 pm-9:11 am

2 stops13h 11m

$672
Cheapest one-way
Quickest one-way

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Mon 8/24

1:14 pm-9:53 pm

2 stops10h 39m

$224

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Mon 8/24

6:00 am-8:43 pm

3 stops16h 43m

$473

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Fri 4/17

10:24 am-9:07 pm

2 stops12h 43m

$505

PortlandSanta Fe

PWM - SAF

PWMSAF

Portland

Fri 4/17

6:04 am-5:08 pm

3 stops13h 04m

$791

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/8

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Portland, Maine-Santa Fe flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Portland, Maine-Santa Fe flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Portland, Maine-Santa Fe flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Santa Fe flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Santa Fe flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santa Fe

What is the cheapest month to book a flight from Portland, Maine to Santa Fe?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Santa Fe (average of $191). Flying from Portland, Maine to Santa Fe in March is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated March 11, 2026.
Get a feel of what it's like to fly with American Airlines from Portland to Santa Fe by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,419 reviews

Boarding

7.5

Food

6.4

Comfort

7.2

Entertainment

6.9

Crew

7.9

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,419 reviews
American Airlines
7.1
Good
11,419 reviews

Boarding

7.5

Food

6.4

Comfort

7.2

Entertainment

6.9

Crew

7.9

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Portland to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Santa Fe?

    Departing from Portland, Maine to Santa Fe will take you 11h 31m. The distance between Portland, Maine and Santa Fe is about 1965 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Portland, Maine to Santa Fe round-trip?

    Our cheapest airline available from Portland, Maine to Santa Fe is American Airlines. Our recent data shows that you can find tickets from as low as $344 on this airline. Users have found that American Airlines is 32% cheaper than the other options available to this destination.

  • Can I find deals for flights from Portland to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Portland to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santa Fe.

  • Can I find deals for business class flights from Portland to Santa Fe?

    Yes. Cheapflights offers flight deals from Portland to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Santa Fe?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Santa Fe (average of $191). Flying from Portland, Maine to Santa Fe in March is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Alternative routes for Portland to Santa Fe

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Portland to Santa Fe

Discover the top airline that operate flights from Portland to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$344Average$484FlexibilityNo cancel feeOn-time71%

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