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$349+ Cheap flights from Louisville to Santa Fe (SDF - SAF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SAF
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Louisville to Santa Fe

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Santa Fe (SAF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$349
(American Airlines)

Popular in

September

Cheapest in

May

Average price

$568
From Louisville Intl to Santa Fe
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($68 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Louisville to Santa Fe

Cheapest flights from Louisville to Santa Fe
Explore the most affordable flight options available from Louisville to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/299:44 amSDF - SAF
1 stop5h 51mAmerican Airlines
Fri 10/3111:44 amSAF - SDF
1 stop6h 48mAmerican Airlines
Deal found 9/11$349
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/299:55 amSDF - SAF
2 stops9h 02mUnited Airlines
Fri 10/311:26 pmSAF - SDF
1 stop7h 04mUnited Airlines
Deal found 9/11$384
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/228:00 amSDF - SAF
1 stop6h 40mUnited Airlines
Sun 11/307:00 amSAF - SDF
1 stop5h 19mUnited Airlines
Deal found 9/10$620
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:45 amSDF - SAF
1 stop5h 43mAmerican Airlines
Sun 11/303:25 pmSAF - SDF
2 stops9h 05mAmerican Airlines
Deal found 9/10$744

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Louisville to Santa Fe that are best for you.

Fly from

Louisville

Fly to

Santa Fe

Route

Depart

Return

Price

LouisvilleSanta Fe

SDF - SAF

SDFSAF

Louisville Intl

Wed 10/29

9:44 am-1:35 pm

1 stop5h 51m

Santa Fe

Fri 10/31

11:44 am-8:32 pm

1 stop6h 48m

$349

LouisvilleSanta Fe

SDF - SAF

SDFSAF

Louisville Intl

Wed 10/29

9:55 am-4:57 pm

2 stops9h 02m

Santa Fe

Fri 10/31

1:26 pm-10:30 pm

1 stop7h 04m

$384

LouisvilleSanta Fe

SDF - SAF

SDFSAF

Louisville Intl

Sat 11/22

8:00 am-12:40 pm

1 stop6h 40m

Santa Fe

Sun 11/30

7:00 am-2:19 pm

1 stop5h 19m

$620

LouisvilleSanta Fe

SDF - SAF

SDFSAF

Louisville Intl

Sat 11/22

5:45 am-9:28 am

1 stop5h 43m

Santa Fe

Sun 11/30

3:25 pm-2:30 am

2 stops9h 05m

$744

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Louisville to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Santa Fe

What is the cheapest month to book a flight from Louisville to Santa Fe?

Currently, January is the cheapest month in which you can book a flight from Louisville to Santa Fe (average of $372). Flying from Louisville to Santa Fe in March is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Louisville to Santa Fe, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Louisville to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Santa Fe?

    There are many flights that can get you from Louisville to Santa Fe in 5h 51m. Fly via American Airlines or United Airlines to get the fastest option. Airlines will cover a distance of 1135 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Louisville to Santa Fe round-trip?

    American Airlines, at $253, was found to be the cheapest airline from Louisville to Santa Fe. An alternate airline flying to your destination would be United Airlines. You may be able to fly from Louisville to Santa Fe for 39% less than the average price by searching for these airlines.

  • Can I find deals for flights from Louisville to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Louisville to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Santa Fe.

  • Can I find deals for business class flights from Louisville to Santa Fe?

    Yes. Cheapflights offers flight deals from Louisville to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Santa Fe?

    Currently, January is the cheapest month in which you can book a flight from Louisville to Santa Fe (average of $372). Flying from Louisville to Santa Fe in March is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Top 2 airlines flying from Louisville to Santa Fe

Discover the top 2 airlines that operate flights from Louisville to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$253Average$384FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$334Average$434FlexibilityNo cancel feeOn-time69%

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