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Santa Fe

$264+ Cheap flights from Iowa to Santa Fe (SAF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAF
Mar 13 — Mar 201
Fri 3/13
Fri 3/20
1 adult, Economy
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Cheap flight deals from Iowa to Santa Fe

Cheapest flights from Iowa to Santa Fe
Explore the most affordable flight options available from Iowa to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.

This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
OMA
-
SAF
1 stop4h 08m
United Airlines
Tue 3/175:53 pm
SAF
-
OMA
1 stop4h 37m
United Airlines
Deal found 2/8$264
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:30 am
DSM
-
SAF
1 stop4h 39m
United Airlines
Sat 5/25:49 pm
SAF
-
DSM
1 stop4h 55m
United Airlines
Deal found 2/9$264
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:09 pm
DSM
-
SAF
1 stop6h 40m
American Airlines
Thu 10/14:58 pm
SAF
-
DSM
1 stop4h 32m
American Airlines
Deal found 2/7$299
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:14 am
OMA
-
SAF
1 stop7h 59m
American Airlines
Sun 3/11:43 pm
SAF
-
OMA
1 stop9h 16m
American Airlines
Deal found 2/10$304
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:30 am
DSM
-
SAF
1 stop5h 04m
United Airlines
Thu 5/71:19 pm
SAF
-
DSM
1 stop5h 57m
United Airlines
Deal found 2/7$328
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:05 am
OMA
-
SAF
1 stop4h 04m
United Airlines
Wed 4/85:49 pm
SAF
-
OMA
1 stop4h 16m
United Airlines
Deal found 2/10$343
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/143:57 pm
OMA
-
SAF
1 stop6h 12m
American Airlines
Sat 2/213:35 pm
SAF
-
OMA
1 stop7h 20m
American Airlines
Deal found 2/10$349
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:44 pm
DSM
-
SAF
1 stop19h 18m
American Airlines
Mon 3/162:35 pm
SAF
-
DSM
1 stop8h 05m
American Airlines
Deal found 2/10$359
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:46 am
CID
-
SAF
1 stop8h 19m
American Airlines
Sun 3/153:35 pm
SAF
-
CID
1 stop7h 23m
American Airlines
Deal found 2/8$370
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:04 am
OMA
-
SAF
1 stop4h 20m
United Airlines
Sat 2/283:20 pm
SAF
-
OMA
1 stop3h 52m
United Airlines
Deal found 2/9$374
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:48 pm
DSM
-
SAF
1 stop6h 11m
American Airlines
Sat 5/305:13 pm
SAF
-
DSM
1 stop5h 46m
American Airlines
Deal found 2/10$375
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:52 am
OMA
-
SAF
1 stop4h 38m
United Airlines
Sat 2/147:00 am
SAF
-
OMA
1 stop4h 40m
United Airlines
Deal found 2/7$419

Find flight deals from Iowa to Santa Fe

Keep the following information in mind while searching for Iowa to Santa Fe flight deals. Data was last updated February 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$264
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$349
Provider with most accurate pricing for Des Moines-Santa Fe flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Santa Fe flights.
Search Deals
From Iowa to Santa Fe
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($103 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Iowa to Santa Fe that are best for you.

Fly from

Iowa

Fly to

Santa Fe

Route

Depart

Return

Price

OmahaSanta Fe

OMA - SAF

OMASAF

Omaha Eppley Airfield

Tue 3/10

6:00 am-9:08 am

1 stop4h 08m

Santa Fe

Tue 3/17

5:53 pm-11:30 pm

1 stop4h 37m

$264

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Mon 4/27

5:30 am-9:09 am

1 stop4h 39m

Santa Fe

Sat 5/2

5:49 pm-11:44 pm

1 stop4h 55m

$264

OmahaSanta Fe

OMA - SAF

OMASAF

Omaha Eppley Airfield

Wed 2/25

6:14 am-1:13 pm

1 stop7h 59m

Santa Fe

Sun 3/1

1:43 pm-11:59 pm

1 stop9h 16m

$304

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Sat 5/2

5:30 am-9:34 am

1 stop5h 04m

Santa Fe

Thu 5/7

1:19 pm-8:16 pm

1 stop5h 57m

$328

OmahaSanta Fe

OMA - SAF

OMASAF

Omaha Eppley Airfield

Sat 4/4

6:05 am-9:09 am

1 stop4h 04m

Santa Fe

Wed 4/8

5:49 pm-11:05 pm

1 stop4h 16m

$343

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Mon 3/9

7:44 pm-2:02 pm

1 stop19h 18m

Santa Fe

Mon 3/16

2:35 pm-11:40 pm

1 stop8h 05m

$359

OmahaSanta Fe

OMA - SAF

OMASAF

Omaha Eppley Airfield

Tue 2/24

6:04 am-9:24 am

1 stop4h 20m

Santa Fe

Sat 2/28

6:00 pm-11:04 pm

1 stop4h 04m

$374

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Wed 5/27

4:48 pm-9:59 pm

1 stop6h 11m

Santa Fe

Sat 5/30

5:13 pm-11:59 pm

1 stop5h 46m

$375

OmahaSanta Fe

OMA - SAF

OMASAF

Omaha Eppley Airfield

Sat 4/4

5:19 am-2:45 pm

2 stops10h 26m

Santa Fe

Wed 4/8

3:25 pm-11:58 pm

1 stop7h 33m

$433

OmahaSanta Fe

OMA - SAF

OMASAF

Omaha Eppley Airfield

Sun 3/22

6:00 am-9:08 am

1 stop4h 08m

Santa Fe

Sun 3/29

5:49 pm-11:05 pm

1 stop4h 16m

$444

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 27 results
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Best time to book a flight from Iowa to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Santa Fe

What is the cheapest month to book a flight from Iowa to Santa Fe?

Currently, April is the cheapest month in which you can book a flight from Iowa to Santa Fe (average of $198). Flying from Iowa to Santa Fe in February is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from Iowa?

    If you book a flight to Santa Fe from Iowa, you will be flying to Santa Fe, which is the city’s only airport. Santa Fe (SAF) is located 9.8 mi from the center of Santa Fe.

  • How long is the flight from Iowa to Santa Fe?

    A quick flight from Iowa to Santa Fe can take about 4h 08m. United Airlines provides one of the quickest options available for as low as $264. The distance between Iowa and Santa Fe is about 676 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Iowa to Santa Fe?

    While some choose either Omaha Eppley Airfield - Santa Fe or Cedar Rapids - Santa Fe, Des Moines - Santa Fe is the most popular route from Iowa to Santa Fe.

  • Can I find deals for flights from Iowa to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Iowa to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Santa Fe.

  • Can I find deals for business class flights from Iowa to Santa Fe?

    Yes. Cheapflights offers flight deals from Iowa to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Santa Fe?

    Currently, April is the cheapest month in which you can book a flight from Iowa to Santa Fe (average of $198). Flying from Iowa to Santa Fe in February is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Alternative routes for Iowa to Santa Fe

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Iowa to Santa Fe

Discover the top 2 airlines that operate flights from Iowa to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$244Average$475FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$249Average$433FlexibilityNo cancel feeOn-time69%

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