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Santa Cruz de la Sierra

$443+ Cheap flights from Portland (PDX) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — VVI
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Portland to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$856
(United Airlines)

One-way from

$443
(United)
From Portland to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Portland to Santa Cruz de la Sierra Viru Viru Intl
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Find flight deals from Portland to Santa Cruz de la Sierra

Cheapest flights from Portland to Santa Cruz de la Sierra
Explore the most affordable flight options available from Portland to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This United deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/81:44 pmPDX - VVI
3 stops33h 06mMultiple Airlines
Tue 10/283:40 amVVI - PDX
3 stops46h 11mMultiple Airlines
Deal found 9/15$865
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/137:30 amPDX - VVI
2 stops36h 10mUnited Airlines
Sun 10/261:09 amVVI - PDX
3 stops24h 42mUnited Airlines
Deal found 9/13$867
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1311:55 pmPDX - VVI
2 stops19h 45mUnited Airlines
Thu 10/161:09 amVVI - PDX
2 stops21h 04mUnited Airlines
Deal found 9/15$877
This Ovago deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1310:30 amPDX - VVI
2 stops41h 14mLATAM Airlines
Mon 10/275:25 amVVI - PDX
2 stops35h 25mLATAM Airlines
Deal found 9/13$1,452
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/139:55 amPDX - VVI
3 stops26h 55mMultiple Airlines
Mon 10/279:05 amVVI - PDX
3 stops32h 40mMultiple Airlines
Deal found 9/13$1,917
This GOL deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1311:48 amPDX - VVI
2 stops20h 17mGOL
Fri 10/171:10 pmVVI - PDX
2 stops24h 46mGOL
Deal found 9/15$2,439

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Portland to Santa Cruz de la Sierra that are best for you.

Fly from

Portland

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Sun 2/1

11:59 pm-10:50 pm

2 stops42h 51m

Santa Cruz de la Sierra Viru Viru Intl

Fri 2/27

1:15 am-10:08 pm

2 stops24h 53m

$856

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Wed 10/8

1:44 pm-1:50 am

3 stops33h 06m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/28

3:40 am-10:51 pm

3 stops46h 11m

$865

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Mon 10/13

7:30 am-10:40 pm

2 stops36h 10m

Santa Cruz de la Sierra Viru Viru Intl

Sun 10/26

3:40 am-10:45 pm

2 stops22h 05m

$866

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Mon 10/13

7:30 am-10:40 pm

2 stops36h 10m

Santa Cruz de la Sierra Viru Viru Intl

Sun 10/26

1:09 am-10:51 pm

3 stops24h 42m

$867

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Mon 10/13

11:55 pm-10:40 pm

2 stops19h 45m

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/16

1:09 am-8:20 pm

3 stops46h 11m

$877

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Tue 2/3

12:59 pm-2:35 am

2 stops33h 36m

$443

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Tue 2/3

5:34 am-10:50 pm

2 stops37h 16m

$444

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Portland to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santa Cruz de la Sierra

What is the cheapest time of day to fly from PDX to VVI?

Find hourly flight availability from Portland to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Portland to Santa Cruz de la Sierra, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated September 16, 2025.
Peruse reviews from past customers who have flown with United Airlines from Portland to Santa Cruz de la Sierra to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,924 reviews

Comfort

7.3

Food

6.6

Crew

8.1

Boarding

7.7

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,924 reviews
United Airlines
7.4
Good
8,924 reviews

Comfort

7.3

Food

6.6

Crew

8.1

Boarding

7.7

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Portland to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland to Santa Cruz de la Sierra?

    For as low as $856, United Airlines can have you in Santa Cruz de la Sierra from Portland in 42h 51m. Airlines will cover a distance of 5729 mi.

  • What is the cheapest airline to fly from Portland to Santa Cruz de la Sierra round-trip?

    Currently priced at $681, United Airlines will fly you from Portland to Santa Cruz de la Sierra and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip.

  • Can I find deals for flights from Portland to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Portland to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Portland to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Portland to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Portland to Santa Cruz de la Sierra (average of $597). Flying from Portland to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Portland to La Paz flights

Top airline flying from Portland to Santa Cruz de la Sierra

Discover the top airline that operate flights from Portland to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$681Average$883FlexibilityNo cancel feeOn-time69%

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