HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Cruz de la Sierra

$444+ Cheap flights from Portland (PDX) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — VVI
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Portland to Santa Cruz de la Sierra

Best flights from Portland to Santa Cruz de la Sierra
Discover carefully curated flight deals from Portland to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 16, 2025.

This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2911:59 pmPDX - VVI
2 stops24h 37mUnited Airlines
Tue 4/1411:48 amVVI - PDX
2 stops35h 43mUnited Airlines
Deal found 12/15$847
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/297:00 amPDX - VVI
1 stop18h 50mMultiple Airlines
Mon 4/132:55 amVVI - PDX
2 stops20h 35mMultiple Airlines
Deal found 12/15$1,067
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/911:59 pmPDX - VVI
2 stops42h 51mUnited Airlines
Sat 2/2111:44 amVVI - PDX
2 stops39h 30mUnited Airlines
Deal found 12/16$857
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:10 amPDX - VVI
2 stops16h 28mUnited Airlines
Thu 3/511:42 amVVI - PDX
2 stops39h 03mUnited Airlines
Deal found 12/14$868

Find flight deals from Portland to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$847
(United Airlines)

One-way from

$444
(United Airlines)
Provider with most accurate pricing for Portland-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Portland to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Portland to Santa Cruz de la Sierra Viru Viru Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Portland to Santa Cruz de la Sierra that are best for you.

Fly from

Portland

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Sun 3/29

11:59 pm-3:36 am

2 stops24h 37m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/14

11:48 am-8:31 pm

2 stops35h 43m

$847

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Mon 2/9

11:59 pm-10:50 pm

2 stops42h 51m

Santa Cruz de la Sierra Viru Viru Intl

Sat 2/21

11:44 am-11:14 pm

2 stops39h 30m

$857

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Mon 3/2

7:10 am-3:38 am

2 stops16h 28m

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/5

11:42 am-10:45 pm

2 stops39h 03m

$868

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Sun 3/29

7:00 am-4:50 am

1 stop18h 50m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/13

2:55 am-8:30 pm

2 stops20h 35m

$1,067

PortlandSanta Cruz de la Sierra

PDX - VVI

PDXVVI

Portland

Tue 2/3

1:24 pm-10:50 pm

2 stops29h 26m

$444

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Compare providers for flights from Portland to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Santa Cruz de la Sierra in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland-Santa Cruz de la Sierra flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland-Santa Cruz de la Sierra flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland-Santa Cruz de la Sierra flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santa Cruz de la Sierra

What is the cheapest time of day to fly from PDX to VVI?

Find hourly flight availability from Portland to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

It’s optimal to fly from Portland to Santa Cruz de la Sierra in the evening. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Portland to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland to Santa Cruz de la Sierra?

    For as low as $847, United Airlines can have you in Santa Cruz de la Sierra from Portland in 24h 37m. Airlines will cover a distance of 5729 mi.

  • Can I find deals for flights from Portland to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Portland to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Portland to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Portland to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Portland to La Paz flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.