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Santa Cruz de la Sierra

$249+ Cheap flights from Marco Island, FL to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — VVI
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Marco Island to Santa Cruz de la Sierra Viru Viru Intl are usually found in April or August, booked 54 days in advance, depart on a Thursday or Tuesday and return on a Tuesday

Cheap flight deals from Marco Island to Santa Cruz de la Sierra

Keep the following information in mind while searching for Marco Island to Santa Cruz de la Sierra flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$395
(Mytrip)

One-way from

$249
(Cheapflightsfares)

Popular in

December

Cheapest in

April

Average price

$579
From Marco Island to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Marco Island to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 11% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Marco Island to Santa Cruz de la Sierra

Cheapest flights from Marco Island to Santa Cruz de la Sierra
Explore the most affordable flight options available from Marco Island to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/165:00 pmMIA - VVI
1 stop8h 50mAvianca
mar. 10/212:50 amVVI - MIA
1 stop9h 40mAvianca
Deal found 9/13$395
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/275:12 pmMIA - VVI
1 stop10h 24mCopa Airlines
lun. 11/1011:40 amVVI - MIA
1 stop14h 05mCopa Airlines
Deal found 9/15$397
This Booking.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/1612:25 pmMIA - VVI
1 stop10h 15mCopa Airlines
mar. 10/2111:59 amVVI - MIA
1 stop10h 43mCopa Airlines
Deal found 9/13$399
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/2111:20 amMIA - VVI
1 stop15h 16mCopa Airlines
vie. 11/281:09 amVVI - MIA
1 stop11h 03mCopa Airlines
Deal found 9/15$443
This Copa Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/2812:46 pmMIA - VVI
1 stop13h 50mCopa Airlines
jue. 12/1111:40 amVVI - MIA
1 stop10h 42mCopa Airlines
Deal found 9/14$472
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/35:45 pmMIA - VVI
3 stops32h 05mAvianca
dom. 10/122:50 amVVI - MIA
1 stop9h 40mAvianca
Deal found 9/13$487
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/295:24 amMIA - VVI
1 stop16h 22mCopa Airlines
sáb. 12/1311:40 amVVI - MIA
1 stop11h 05mCopa Airlines
Deal found 9/15$490
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/136:29 pmMIA - VVI
1 stop27h 56mCopa Airlines
mié. 9/1712:15 pmVVI - MIA
1 stop24h 05mCopa Airlines
Deal found 9/13$505
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/195:00 pmMIA - VVI
1 stop8h 50mAvianca
sáb. 9/272:50 amVVI - MIA
1 stop15h 05mAvianca
Deal found 9/14$509
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/2512:24 pmMIA - VVI
1 stop10h 01mCopa Airlines
mar. 9/3012:15 pmVVI - MIA
1 stop13h 21mCopa Airlines
Deal found 9/15$518
This Viajes Éxito deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Viajes Éxito is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/143:10 pmMIA - VVI
2 stops34h 40mAvianca
lun. 10/202:50 amVVI - MIA
2 stops35h 05mAvianca
Deal found 9/14$520

Cheapflights Fare Finder

 
Customize your flight search to find flights from Marco Island to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Marco Island to Santa Cruz de la Sierra that are best for you.

Fly from

Marco Island

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

lun. 10/27

6:23 am-10:40 pm

1 stop16h 17m

Santa Cruz de la Sierra Viru Viru Intl

dom. 11/9

1:09 am-6:51 pm

1 stop18h 42m

$397

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

vie. 10/24

12:25 pm-10:40 pm

1 stop10h 15m

Santa Cruz de la Sierra Viru Viru Intl

lun. 10/27

11:41 am-10:25 pm

1 stop10h 44m

$397

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

sáb. 11/1

5:59 am-10:46 pm

1 stop16h 47m

Santa Cruz de la Sierra Viru Viru Intl

sáb. 11/15

11:40 am-9:22 pm

1 stop10h 42m

$397

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

vie. 10/17

12:25 pm-10:40 pm

1 stop10h 15m

Santa Cruz de la Sierra Viru Viru Intl

vie. 10/31

1:09 am-2:49 pm

1 stop13h 40m

$397

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

jue. 11/20

7:32 am-10:46 pm

1 stop14h 14m

Santa Cruz de la Sierra Viru Viru Intl

jue. 11/27

1:09 am-6:51 pm

1 stop18h 42m

$443

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

lun. 9/29

5:21 pm-3:36 am

1 stop10h 15m

Santa Cruz de la Sierra Viru Viru Intl

jue. 10/2

1:09 am-7:55 pm

1 stop18h 46m

$443

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

vie. 11/7

4:59 am-10:46 pm

1 stop16h 47m

$250

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

mié. 12/3

5:34 am-10:46 pm

1 stop16h 12m

$250

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

vie. 9/26

12:24 pm-3:36 am

1 stop15h 12m

$250

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

dom. 9/28

2:20 pm-3:36 am

1 stop13h 16m

$250

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 14 results
1
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Best time to book a flight from Marco Island to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Marco Island with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Marco Island to Santa Cruz de la Sierra

How far ahead should I book a flight from Marco Island to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Marco Island to Santa Cruz de la Sierra. Price data was last updated on September 12, 2025.

The best time to book flights from Marco Island to Santa Cruz de la Sierra is 54 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Marco Island to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Marco Island to Santa Cruz de la Sierra (average of $597). Flying from Marco Island to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MA9 to VVI?

Find hourly flight availability from Marco Island to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Marco Island to Santa Cruz de la Sierra as you normally would.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated septiembre 15, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, LATAM Airlines, and BoA from Marco Island to Santa Cruz de la Sierra to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Overall

7.6

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Overall

7.6

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
LATAM Airlines
7.5
Good
1,847 reviews
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Overall

7.6

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
BoA
6.8
Okay
136 reviews
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Overall

7.6

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Overall

7.6

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Marco Island to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Marco Island?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Marco Island to Santa Cruz de la Sierra. 4 airlines have flights to Viru Viru Intl from Marco Island on a regular basis. Booking flights from Marco Island to Santa Cruz de la Sierra Viru Viru Intl should not be difficult; the airport handles an average of 0 inbound flights from Marco Island per day.

  • How popular is this Marco Island to Santa Cruz de la Sierra flight route?

    This flight path from Marco Island to Santa Cruz de la Sierra Viru Viru Intl was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Marco Island to Santa Cruz de la Sierra?

    There are many flights that can get you from Marco Island to Santa Cruz de la Sierra in 16h 17m. Fly via Copa Airlines to get the fastest option. Airlines will cover a distance of 3213 mi.

  • What are the cheapest flights from Marco Island to Santa Cruz de la Sierra?

    The cheapest flight price from Marco Island to Santa Cruz de la Sierra is $275. On average you can expect to pay $1,005. The most popular route, (Miami - Santa Cruz de la Sierra Viru Viru Intl), can usually be booked for $390.

  • Can I find deals for flights from Marco Island to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Marco Island to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Marco Island to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Marco Island to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Marco Island to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Marco Island to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Marco Island to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Marco Island to Santa Cruz de la Sierra (average of $597). Flying from Marco Island to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Marco Island to Santa Cruz de la Sierra

Discover the top 4 airlines that operate flights from Marco Island to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$376Average$470FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$379Average$537FlexibilityNo cancel feeOn-time70%
BoACheapest$526Average$693FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$532Average$637FlexibilityNo cancel feeOn-time81%

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