$456+ Cheap flights from Houston to Santa Cruz de la Sierra (VVI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/20. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — VVI
Aug 2 — Aug 91
Round-trip
1 adult, Economy
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Find cheap flights from Houston to Santa Cruz de la Sierra with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Santa Cruz de la Sierra
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Cheapest flights from Houston to Santa Cruz de la SierraExplore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2026.
Explore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2026.
This KAYAK deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:03 am
IAH
- VVI
1 stop11h 41m
Copa Airlines
Sun 9/201:12 am
VVI
- IAH
1 stop14h 05m
Copa Airlines
Deal found 6/29![Copa Airlines logo]()
$842
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:15 am
IAH
- VVI
2 stops20h 23m
United Airlines
Mon 9/1411:47 am
VVI
- IAH
2 stops23h 39m
United Airlines
Deal found 7/3![United Airlines logo]()
$843
This oojo deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Tue 9/153:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 7/3![Avianca logo]()
$855
This oojo deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Sat 8/223:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 6/29![Avianca logo]()
$857
This FlightHub deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:05 pm
IAH
- VVI
2 stops35h 25m
Avianca
Mon 9/143:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 7/3![Avianca logo]()
$863
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:19 pm
IAH
- VVI
2 stops28h 19m
United Airlines
Sat 9/1911:47 am
VVI
- IAH
2 stops21h 57m
United Airlines
Deal found 7/3![United Airlines logo]()
$868
This oojo deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Fri 8/143:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 6/29![Avianca logo]()
$874
This Justfly.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Sat 8/13:35 am
VVI
- IAH
2 stops33h 30m
Avianca
Deal found 6/30![Avianca logo]()
$879
This FlightHub deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Sat 7/253:35 am
VVI
- IAH
2 stops33h 30m
Avianca
Deal found 7/1![Avianca logo]()
$880
This Avianca deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:45 am
IAH
- VVI
2 stops17h 45m
Avianca
Fri 8/213:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 7/1![Avianca logo]()
$883
This KAYAK deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:25 pm
IAH
- VVI
2 stops25h 15m
Copa Airlines
Sat 8/221:12 am
VVI
- IAH
1 stop19h 44m
Copa Airlines
Deal found 6/29![Copa Airlines logo]()
$888
This KAYAK deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:00 am
HOU
- VVI
2 stops20h 35m
LATAM Airlines
Sun 12/135:30 am
VVI
- HOU
2 stops29h 56m
LATAM Airlines
Deal found 6/30![LATAM Airlines logo]()
$1,591
Best flights from Houston to Santa Cruz de la SierraDiscover carefully curated flight deals from Houston to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2026.
Discover carefully curated flight deals from Houston to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2026.
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:19 pm
IAH
- VVI
2 stops28h 19m
United Airlines
Tue 9/1511:47 am
VVI
- IAH
2 stops35h 43m
United Airlines
Deal found 7/3![United Airlines logo]()
$843
This Avianca deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:45 am
IAH
- VVI
2 stops17h 45m
Avianca
Fri 8/213:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 7/1![Avianca logo]()
$883
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:37 pm
IAH
- VVI
2 stops25h 03m
Multiple Airlines
Sat 8/228:35 am
VVI
- IAH
1 stop25h 09m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$920
This KAYAK deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:00 pm
IAH
- VVI
1 stop13h 42m
Copa Airlines
Sat 12/121:10 am
VVI
- IAH
1 stop15h 44m
Copa Airlines
Deal found 6/30![Copa Airlines logo]()
$939
This Orbitz deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 am
HOU
- VVI
2 stops45h 35m
LATAM Airlines
Sat 8/295:25 am
VVI
- HOU
2 stops29h 25m
LATAM Airlines
Deal found 7/1![LATAM Airlines logo]()
$1,637
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:15 am
IAH
- VVI
2 stops20h 23m
United Airlines
Thu 9/1711:47 am
VVI
- IAH
2 stops23h 39m
United Airlines
Deal found 7/3![United Airlines logo]()
$843
This Avianca deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Wed 8/193:35 am
VVI
- IAH
2 stops37h 35m
Avianca
Deal found 7/3![Avianca logo]()
$901
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:20 am
IAH
- VVI
2 stops19h 18m
United Airlines
Mon 9/2111:47 am
VVI
- IAH
2 stops23h 39m
United Airlines
Deal found 6/30![United Airlines logo]()
$843
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:20 am
IAH
- VVI
2 stops38h 20m
United Airlines
Thu 8/2011:47 am
VVI
- IAH
2 stops37h 09m
United Airlines
Deal found 6/29![United Airlines logo]()
$843
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:19 pm
IAH
- VVI
2 stops28h 19m
United Airlines
Sat 9/1911:47 am
VVI
- IAH
2 stops21h 57m
United Airlines
Deal found 7/3![United Airlines logo]()
$868
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:20 pm
IAH
- VVI
2 stops25h 24m
United Airlines
Sat 9/1911:47 am
VVI
- IAH
2 stops21h 57m
United Airlines
Deal found 7/3![United Airlines logo]()
$893
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:53 pm
IAH
- VVI
2 stops31h 47m
United Airlines
Sat 8/2911:47 am
VVI
- IAH
2 stops23h 38m
United Airlines
Deal found 7/1![United Airlines logo]()
$893
This KAYAK deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/910:50 am
HOU
- VVI
2 stops16h 45m
LATAM Airlines
Sat 8/155:25 am
VVI
- HOU
2 stops29h 25m
LATAM Airlines
Deal found 6/29![LATAM Airlines logo]()
$1,982
This Expedia deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:20 pm
HOU
- VVI
2 stops34h 15m
LATAM Airlines
Thu 8/2011:15 am
VVI
- HOU
2 stops23h 35m
LATAM Airlines
Deal found 7/1![LATAM Airlines logo]()
$2,021
This KAYAK deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:17 pm
HOU
- VVI
2 stops34h 18m
LATAM Airlines
Sat 8/225:25 am
VVI
- HOU
2 stops31h 51m
LATAM Airlines
Deal found 7/1![LATAM Airlines logo]()
$2,343
This Expedia deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:55 pm
HOU
- VVI
2 stops38h 40m
LATAM Airlines
Thu 8/135:25 am
VVI
- HOU
2 stops31h 51m
LATAM Airlines
Deal found 7/1![LATAM Airlines logo]()
$2,640
This Expedia deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:17 pm
HOU
- VVI
2 stops37h 39m
LATAM Airlines
Thu 8/135:25 am
VVI
- HOU
2 stops31h 51m
LATAM Airlines
Deal found 7/1![LATAM Airlines logo]()
$2,686
This Justfly.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:20 pm
HOU
- VVI
2 stops37h 36m
LATAM Airlines
Mon 9/215:25 am
VVI
- HOU
2 stops29h 36m
LATAM Airlines
Deal found 7/3![LATAM Airlines logo]()
$2,817
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:40 am
HOU
- VVI
2 stops16h 55m
LATAM Airlines
Wed 8/128:41 am
VVI
- HOU
2 stops28h 35m
LATAM Airlines
Deal found 7/1![LATAM Airlines logo]()
$3,223
Last-minute flights from Houston to Santa Cruz de la SierraDiscover last-minute flight deals from Houston to Santa Cruz de la Sierra. Data last updated July 3, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Santa Cruz de la Sierra. Data last updated July 3, 2026 and is based on user searches.
This Justfly.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Sat 8/13:35 am
VVI
- IAH
2 stops33h 30m
Avianca
Deal found 6/30![Avianca logo]()
$879
This FlightHub deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Sat 7/253:35 am
VVI
- IAH
2 stops33h 30m
Avianca
Deal found 7/1![Avianca logo]()
$880
This FlightHub deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Sun 8/23:35 am
VVI
- IAH
2 stops33h 30m
Avianca
Deal found 6/30![Avianca logo]()
$896
This oojo deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Sat 8/223:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 6/29![Avianca logo]()
$857
This FlightHub deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:05 pm
IAH
- VVI
2 stops35h 25m
Avianca
Wed 8/193:35 am
VVI
- IAH
2 stops37h 35m
Avianca
Deal found 7/3![Avianca logo]()
$863
This KAYAK deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:25 pm
IAH
- VVI
2 stops25h 15m
Copa Airlines
Sat 8/221:12 am
VVI
- IAH
1 stop19h 44m
Copa Airlines
Deal found 6/29![Copa Airlines logo]()
$888
This KAYAK deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:18 pm
IAH
- VVI
2 stops27h 22m
Copa Airlines
Wed 8/191:12 am
VVI
- IAH
1 stop19h 44m
Copa Airlines
Deal found 7/3![Copa Airlines logo]()
$895
This oojo deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Fri 8/143:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 6/29![Avianca logo]()
$874
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:20 am
IAH
- VVI
2 stops38h 20m
United Airlines
Thu 8/2011:47 am
VVI
- IAH
2 stops37h 09m
United Airlines
Deal found 6/29![United Airlines logo]()
$843
This Avianca deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:45 am
IAH
- VVI
2 stops17h 45m
Avianca
Fri 8/213:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 7/1![Avianca logo]()
$883
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:53 pm
IAH
- VVI
2 stops31h 47m
United Airlines
Sat 8/2911:47 am
VVI
- IAH
2 stops23h 38m
United Airlines
Deal found 7/1![United Airlines logo]()
$893
This Orbitz deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 am
HOU
- VVI
2 stops45h 35m
LATAM Airlines
Sat 8/295:25 am
VVI
- HOU
2 stops29h 25m
LATAM Airlines
Deal found 7/1![LATAM Airlines logo]()
$1,637
One-way flights from Houston to Santa Cruz de la SierraSearch for one-way flight options from Houston to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated July 3, 2026.
Search for one-way flight options from Houston to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated July 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:55 pm
IAH
- VVI
3 stops52h 35m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$456
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:23 pm
IAH
- VVI
2 stops50h 17m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$474
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:55 pm
IAH
- VVI
3 stops48h 45m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:00 am
HOU
- VVI
3 stops43h 30m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$524
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:37 pm
IAH
- VVI
3 stops54h 58m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$533
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1112:05 pm
IAH
- VVI
3 stops33h 35m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$549
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:10 pm
IAH
- VVI
3 stops28h 25m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$553
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1212:05 pm
IAH
- VVI
3 stops33h 35m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$592
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/127:03 pm
HOU
- VVI
3 stops26h 37m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$840
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:39 pm
HOU
- VVI
3 stops55h 56m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$853
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/141:58 pm
HOU
- VVI
3 stops44h 22m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$1,066
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:39 pm
HOU
- VVI
3 stops50h 01m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$1,157
Find flight deals from Houston to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2026.
Round-trip from | $842 (KAYAK) |
|---|---|
One-way from | $456 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $1,080 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from Houston to Santa Cruz de la Sierra that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Sun 9/6
10:19 pm-3:38 am
2 stops28h 19m
Santa Cruz de la Sierra Viru Viru Intl
Tue 9/15
11:47 am-10:30 pm
2 stops35h 43m
$843
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Wed 9/9
6:15 am-3:38 am
2 stops20h 23m
Santa Cruz de la Sierra Viru Viru Intl
Thu 9/17
11:47 am-10:26 am
2 stops23h 39m
$843
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Mon 9/7
7:20 am-3:38 am
2 stops19h 18m
Santa Cruz de la Sierra Viru Viru Intl
Mon 9/21
11:47 am-10:26 am
2 stops23h 39m
$843
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Thu 8/13
7:20 am-10:40 pm
2 stops38h 20m
Santa Cruz de la Sierra Viru Viru Intl
Thu 8/20
11:47 am-11:56 pm
2 stops37h 09m
$843
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Sun 9/6
10:19 pm-3:38 am
2 stops28h 19m
Santa Cruz de la Sierra Viru Viru Intl
Sat 9/19
11:47 am-8:44 am
2 stops21h 57m
$868
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Sat 8/15
7:45 am-2:30 am
2 stops17h 45m
Santa Cruz de la Sierra Viru Viru Intl
Fri 8/21
3:35 am-4:10 pm
2 stops13h 35m
$883
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Thu 9/10
8:20 pm-10:44 pm
2 stops25h 24m
Santa Cruz de la Sierra Viru Viru Intl
Sat 9/19
11:47 am-8:44 am
2 stops21h 57m
$893
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Sat 8/15
1:53 pm-10:40 pm
2 stops31h 47m
Santa Cruz de la Sierra Viru Viru Intl
Sat 8/29
11:47 am-10:25 am
2 stops23h 38m
$893
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Mon 8/17
5:45 pm-2:30 am
2 stops31h 45m
Santa Cruz de la Sierra Viru Viru Intl
Wed 8/19
3:35 am-4:10 pm
2 stops37h 35m
$901
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Sat 8/15
8:37 pm-10:40 pm
2 stops25h 03m
Santa Cruz de la Sierra Viru Viru Intl
Sat 8/22
8:35 am-8:44 am
1 stop25h 09m
$920
Showing 1-10 of 36 resultsSorted by cheapest first
Best time to book a flight from Houston to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Houston with our price prediction graph.
HO1-VVI
IAH-VVI
HOU-VVI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Santa Cruz de la Sierra
HO1-VVI
IAH-VVI
HOU-VVI
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Santa Cruz de la Sierra
Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated July 3, 2026.
Read reviews from past customers who have flown Copa Airlines,United Airlines, andAvianca from Houston to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Overall
7.6
Boarding
7.8
Food
6.9
Crew
8.1
Comfort
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Entertainment
6.8
Overall
7.6
Boarding
7.8
Food
6.9
Crew
8.1
Comfort
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Entertainment
6.8
Overall
7.6
Boarding
7.8
Food
6.9
Crew
8.1
Comfort
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Entertainment
6.8
Overall
7.6
Boarding
7.8
Food
6.9
Crew
8.1
Comfort
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Related info for your journey
Find useful and relevant information for your journey from Houston to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Houston to Santa Cruz de la Sierra
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Complete your trip
Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Houston to Santa Cruz de la Sierra by cabin class
Find flights from Houston to Santa Cruz de la Sierra, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Houston and Santa Cruz de la Sierra flights
Browse other Houston and Santa Cruz de la Sierra flight options. Last updated on July 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Houston to Santa Cruz de la Sierra
Discover the top 3 airlines that operate flights from Houston to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$709 | Average$1,204 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$726 | Average$1,301 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$799 | Average$874 | FlexibilityNo cancel fee | On-time71% |