$363+ Cheap flights from Houston to Santa Cruz de la Sierra (VVI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — VVI
Sep 18 — Sep 251
Round-trip
1 adult, Economy
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Find cheap flights from Houston to Santa Cruz de la Sierra with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Santa Cruz de la Sierra
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Cheapest flights from Houston to Santa Cruz de la SierraExplore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
Explore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:40 am -
2 stops34h 58m
Wed 12/2311:42 am -
2 stops38h 33m
Deal found 8/18![United Airlines logo]()
$843
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:18 pm -
1 stop25h 42m
Sat 9/261:12 am -
2 stops37h 21m
Deal found 8/14![Multiple Airlines logo]()
$850
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:20 am -
2 stops39h 24m
Thu 10/2911:55 am -
2 stops33h 35m
Deal found 8/15![United Airlines logo]()
$852
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:25 am -
2 stops34h 13m
Thu 12/2411:42 am -
2 stops39h 48m
Deal found 8/18![United Airlines logo]()
$854
This FlightHub deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:45 pm -
2 stops31h 45m
Sun 9/203:35 am -
2 stops13h 35m
Deal found 8/14![Avianca logo]()
$863
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:20 pm -
2 stops30h 18m
Thu 10/811:47 am -
2 stops37h 12m
Deal found 8/17![United Airlines logo]()
$868
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/281:00 pm -
2 stops35h 35m
Fri 12/253:40 am -
2 stops33h 25m
Deal found 8/18![Avianca logo]()
$880
This United deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:45 pm -
2 stops31h 53m
Sat 11/1411:49 am -
1 stop10h 19m
Deal found 8/18![Multiple Airlines logo]()
$883
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:20 pm -
2 stops31h 22m
Sat 1/911:53 am -
2 stops38h 21m
Deal found 8/18![United Airlines logo]()
$893
This Avianca deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:35 pm -
2 stops32h 00m
Wed 12/233:40 am -
2 stops33h 25m
Deal found 8/18![Avianca logo]()
$901
This Trip.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:28 pm -
2 stops29h 07m
Sat 11/283:40 am -
2 stops31h 21m
Deal found 8/16![Multiple Airlines logo]()
$915
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1210:25 am -
2 stops40h 10m
Sat 1/165:30 am -
2 stops29h 56m
Deal found 8/18![LATAM Airlines logo]()
$2,205
Best flights from Houston to Santa Cruz de la SierraDiscover carefully curated flight deals from Houston to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
Discover carefully curated flight deals from Houston to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:40 am -
2 stops34h 58m
Wed 12/2311:42 am -
2 stops38h 33m
Deal found 8/18![United Airlines logo]()
$843
This Avianca deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:45 pm -
2 stops31h 45m
Fri 9/43:35 am -
2 stops37h 35m
Deal found 8/18![Avianca logo]()
$901
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:18 pm -
1 stop25h 42m
Sun 9/2711:35 pm -
1 stop14h 58m
Deal found 8/14![Multiple Airlines logo]()
$916
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:20 am -
2 stops39h 24m
Thu 10/2911:55 am -
2 stops33h 35m
Deal found 8/15![United Airlines logo]()
$852
This Avianca deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:05 pm -
2 stops35h 25m
Thu 10/223:35 am -
2 stops13h 35m
Deal found 8/18![Avianca logo]()
$917
This United deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:20 am -
2 stops18h 17m
Sat 11/283:40 am -
1 stop28h 05m
Deal found 8/16![Multiple Airlines logo]()
$931
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:45 pm -
2 stops31h 53m
Sat 11/1411:49 am -
2 stops37h 05m
Deal found 8/18![United Airlines logo]()
$868
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:45 pm -
2 stops31h 45m
Tue 9/153:35 am -
2 stops37h 35m
Deal found 8/14![Avianca logo]()
$917
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:18 pm -
1 stop12h 32m
Wed 10/71:12 am -
2 stops37h 03m
Deal found 8/16![Multiple Airlines logo]()
$981
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:20 pm -
2 stops31h 22m
Sat 1/911:53 am -
2 stops38h 21m
Deal found 8/18![United Airlines logo]()
$893
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:50 am -
2 stops44h 06m
Mon 9/215:25 am -
2 stops32h 53m
Deal found 8/18![LATAM Airlines logo]()
$3,821
This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:30 pm -
3 stops63h 01m
Sun 11/295:30 am -
2 stops34h 40m
Deal found 8/16![LATAM Airlines logo]()
$4,246
Last-minute flights from Houston to Santa Cruz de la SierraDiscover last-minute flight deals from Houston to Santa Cruz de la Sierra. Data last updated August 19, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Santa Cruz de la Sierra. Data last updated August 19, 2026 and is based on user searches.
This oojo deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:05 pm -
2 stops35h 25m
Sat 8/223:35 am -
2 stops33h 30m
Deal found 8/16![Avianca logo]()
$964
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:49 am -
2 stops15h 46m
Fri 8/2111:35 pm -
1 stop13h 18m
Deal found 8/15![Multiple Airlines logo]()
$975
This Travelocity deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am -
2 stops21h 35m
Fri 8/215:25 am -
2 stops36h 00m
Deal found 8/15![LATAM Airlines logo]()
$3,121
This Avianca deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:05 pm -
2 stops35h 25m
Sun 8/303:35 am -
2 stops37h 35m
Deal found 8/15![Avianca logo]()
$901
This FlightHub deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:45 pm -
2 stops31h 45m
Sun 9/203:35 am -
2 stops13h 35m
Deal found 8/14![Avianca logo]()
$863
This KAYAK deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:03 am -
1 stop11h 41m
Mon 9/2111:47 am -
1 stop33h 09m
Deal found 8/14![Copa Airlines logo]()
$963
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:26 pm -
1 stop12h 12m
Mon 9/2111:47 am -
2 stops22h 32m
Deal found 8/18![United Airlines logo]()
$1,063
This Justfly.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:50 am -
2 stops44h 06m
Mon 9/215:25 am -
2 stops32h 53m
Deal found 8/17![LATAM Airlines logo]()
$3,821
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:45 pm -
2 stops31h 45m
Tue 9/153:35 am -
2 stops37h 35m
Deal found 8/14![Avianca logo]()
$917
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:18 pm -
1 stop25h 42m
Sat 9/261:12 am -
2 stops37h 21m
Deal found 8/14![Multiple Airlines logo]()
$850
One-way flights from Houston to Santa Cruz de la SierraSearch for one-way flight options from Houston to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated August 19, 2026.
Search for one-way flight options from Houston to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated August 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:32 pm -
3 stops53h 12m
Deal found 8/16![Multiple Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:15 am -
2 stops35h 33m
Deal found 8/18![Multiple Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:11 pm -
2 stops25h 33m
Deal found 8/19![Multiple Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:15 am -
2 stops35h 33m
Deal found 8/18![Multiple Airlines logo]()
$397
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/94:22 pm -
3 stops32h 13m
Deal found 8/18![Multiple Airlines logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:29 am -
3 stops36h 15m
Deal found 8/16![Multiple Airlines logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:11 pm -
3 stops49h 33m
Deal found 8/16![Multiple Airlines logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:10 pm -
3 stops28h 25m
Deal found 8/18![Multiple Airlines logo]()
$466
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:20 pm -
3 stops58h 10m
Deal found 8/19![Multiple Airlines logo]()
$1,192
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:13 pm -
3 stops32h 31m
Deal found 8/16![Multiple Airlines logo]()
$1,267
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:13 pm -
2 stops38h 22m
Deal found 8/16![LATAM Airlines logo]()
$1,484
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:13 pm -
3 stops32h 31m
Deal found 8/16![Multiple Airlines logo]()
$1,509
Find flight deals from Houston to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 19, 2026.
Round-trip from | $843 (United Airlines) |
|---|---|
One-way from | $363 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2026.
Use the filters below to find and compare flights from Houston to Santa Cruz de la Sierra that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSanta Cruz de la Sierra
IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl
IAHVVI
Houston George Bush Intcntl
Thu 11/26
9:40 am-10:38 pm
2 stops34h 58m
Santa Cruz de la Sierra Viru Viru Intl
Wed 12/23
11:42 am-12:15 am
2 stops38h 33m
$843
HoustonSanta Cruz de la Sierra
IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl
IAHVVI
Houston George Bush Intcntl
Thu 10/22
6:20 am-10:44 pm
2 stops39h 24m
Santa Cruz de la Sierra Viru Viru Intl
Thu 10/29
11:55 am-8:30 pm
2 stops33h 35m
$852
HoustonSanta Cruz de la Sierra
IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl
IAHVVI
Houston George Bush Intcntl
Thu 11/5
12:45 pm-10:38 pm
2 stops31h 53m
Santa Cruz de la Sierra Viru Viru Intl
Sat 11/14
11:49 am-10:54 pm
2 stops37h 05m
$868
HoustonSanta Cruz de la Sierra
IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl
IAHVVI
Houston George Bush Intcntl
Sat 12/5
6:20 pm-3:42 am
2 stops31h 22m
Santa Cruz de la Sierra Viru Viru Intl
Sat 1/9
11:53 am-12:14 am
2 stops38h 21m
$893
HoustonSanta Cruz de la Sierra
IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl
IAHVVI
Houston George Bush Intcntl
Tue 9/1
5:45 pm-2:30 am
2 stops31h 45m
Santa Cruz de la Sierra Viru Viru Intl
Fri 9/4
3:35 am-4:10 pm
2 stops37h 35m
$901
Quickest round-trip
HoustonSanta Cruz de la Sierra
IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl
IAHVVI
Houston George Bush Intcntl
Mon 9/21
2:18 pm-5:00 pm
1 stop25h 42m
Santa Cruz de la Sierra Viru Viru Intl
Sun 9/27
11:35 pm-1:33 pm
1 stop14h 58m
$916
HoustonSanta Cruz de la Sierra
IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl
IAHVVI
Houston George Bush Intcntl
Mon 10/19
2:05 pm-2:30 am
2 stops35h 25m
Santa Cruz de la Sierra Viru Viru Intl
Thu 10/22
3:35 am-4:10 pm
2 stops13h 35m
$917
HoustonSanta Cruz de la Sierra
IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl
IAHVVI
Houston George Bush Intcntl
Sun 9/13
5:45 pm-2:30 am
2 stops31h 45m
Santa Cruz de la Sierra Viru Viru Intl
Tue 9/15
3:35 am-4:10 pm
2 stops37h 35m
$917
HoustonSanta Cruz de la Sierra
IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl
IAHVVI
Houston George Bush Intcntl
Mon 11/9
7:20 am-3:37 am
2 stops18h 17m
Santa Cruz de la Sierra Viru Viru Intl
Sat 11/28
3:40 am-5:45 am
1 stop28h 05m
$931
HoustonSanta Cruz de la Sierra
IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl
IAHVVI
Houston George Bush Intcntl
Thu 10/1
2:18 pm-3:50 am
1 stop12h 32m
Santa Cruz de la Sierra Viru Viru Intl
Wed 10/7
1:12 am-1:15 pm
2 stops37h 03m
$981
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Houston to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Houston with our price prediction graph.
HO1-VVI
IAH-VVI
HOU-VVI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Santa Cruz de la Sierra
HO1-VVI
IAH-VVI
HOU-VVI
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Santa Cruz de la Sierra
Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated August 19, 2026.
Read reviews from past customers who have flown Copa Airlines and United Airlines from Houston to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Boarding
7.8
Food
6.9
Entertainment
6.8
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Boarding
7.8
Food
6.9
Entertainment
6.8
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Boarding
7.8
Food
6.9
Entertainment
6.8
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Houston to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Houston and Santa Cruz de la Sierra flights
Browse other Houston and Santa Cruz de la Sierra flight options. Last updated on August 19, 2026.
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Top 2 airlines flying from Houston to Santa Cruz de la Sierra
Discover the top 2 airlines that operate flights from Houston to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$709 | Average$1,221 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$741 | Average$1,666 | FlexibilityNo cancel fee | On-time69% |