$407+ Cheap flights from Houston to Santa Cruz de la Sierra (VVI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/17. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — VVI
Jun 10 — Jun 171
Round-trip
1 adult, Economy
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Find cheap flights from Houston to Santa Cruz de la Sierra with Cheapflights
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Cheapest flights from Houston to Santa Cruz de la SierraExplore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
Explore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:00 am
IAH
- VVI
2 stops21h 38m
United Airlines
Mon 9/2111:47 am
VVI
- IAH
2 stops23h 39m
United Airlines
Deal found 5/11![United Airlines logo]()
$843
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:01 am
IAH
- VVI
2 stops39h 37m
United Airlines
Mon 6/1511:47 am
VVI
- IAH
2 stops37h 58m
United Airlines
Deal found 5/9![United Airlines logo]()
$854
This FlightHub deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Sat 5/233:35 am
VVI
- IAH
2 stops37h 35m
Avianca
Deal found 5/9![Avianca logo]()
$863
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:45 pm
IAH
- VVI
2 stops23h 05m
United Airlines
Wed 12/211:44 am
VVI
- IAH
2 stops34h 44m
United Airlines
Deal found 5/9![United Airlines logo]()
$868
This Justfly.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Wed 5/273:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 5/11![Avianca logo]()
$872
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:10 pm
IAH
- VVI
2 stops24h 40m
United Airlines
Tue 12/111:44 am
VVI
- IAH
2 stops34h 44m
United Airlines
Deal found 5/9![United Airlines logo]()
$878
This Justfly.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Mon 8/103:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 5/10![Avianca logo]()
$880
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/309:55 pm
IAH
- VVI
2 stops51h 49m
United Airlines
Wed 1/1311:44 am
VVI
- IAH
2 stops27h 19m
United Airlines
Deal found 5/7![United Airlines logo]()
$887
This KAYAK deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:03 am
IAH
- VVI
1 stop16h 35m
Copa Airlines
Sun 9/201:12 am
VVI
- IAH
1 stop19h 44m
Copa Airlines
Deal found 5/11![Copa Airlines logo]()
$892
This Avianca deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Fri 5/223:35 am
VVI
- IAH
2 stops37h 35m
Avianca
Deal found 5/8![Avianca logo]()
$901
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:25 pm
IAH
- VVI
2 stops26h 25m
United Airlines
Tue 12/111:44 am
VVI
- IAH
2 stops46h 36m
United Airlines
Deal found 5/9![United Airlines logo]()
$903
This Ovago deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:20 pm
IAH
- VVI
2 stops25h 18m
Copa Airlines
Thu 8/61:12 am
VVI
- IAH
1 stop19h 52m
Copa Airlines
Deal found 5/11![Copa Airlines logo]()
$914
Best flights from Houston to Santa Cruz de la SierraDiscover carefully curated flight deals from Houston to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
Discover carefully curated flight deals from Houston to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1610:19 pm
IAH
- VVI
2 stops28h 16m
United Airlines
Thu 8/2011:47 am
VVI
- IAH
2 stops21h 57m
United Airlines
Deal found 5/10![United Airlines logo]()
$843
This Ovago deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:20 pm
IAH
- VVI
2 stops25h 18m
Copa Airlines
Thu 8/61:12 am
VVI
- IAH
1 stop19h 52m
Copa Airlines
Deal found 5/11![Copa Airlines logo]()
$914
This FlightHub deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:05 pm
IAH
- VVI
2 stops35h 25m
Avianca
Fri 8/73:35 am
VVI
- IAH
2 stops33h 30m
Avianca
Deal found 5/8![Avianca logo]()
$927
This Expedia deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:35 pm
HOU
- VVI
2 stops34h 00m
LATAM Airlines
Mon 10/195:25 am
VVI
- HOU
2 stops29h 01m
LATAM Airlines
Deal found 5/7![LATAM Airlines logo]()
$1,271
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:19 pm
IAH
- VVI
2 stops23h 25m
United Airlines
Mon 9/2111:47 am
VVI
- IAH
2 stops21h 57m
United Airlines
Deal found 5/8![United Airlines logo]()
$843
This FlightHub deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Thu 8/63:35 am
VVI
- IAH
2 stops33h 30m
Avianca
Deal found 5/11![Avianca logo]()
$927
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/62:43 pm
IAH
- VVI
2 stops35h 48m
United Airlines
Sat 6/1311:47 am
VVI
- IAH
2 stops45h 48m
United Airlines
Deal found 5/9![United Airlines logo]()
$939
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:30 am
IAH
- VVI
2 stops17h 08m
United Airlines
Mon 10/1911:47 am
VVI
- IAH
1 stop27h 30m
United Airlines
Deal found 5/7![United Airlines logo]()
$1,058
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:03 am
HOU
- VVI
2 stops48h 53m
LATAM Airlines
Mon 6/155:25 am
VVI
- HOU
2 stops41h 18m
LATAM Airlines
Deal found 5/9![LATAM Airlines logo]()
$1,650
This Expedia deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:06 pm
HOU
- VVI
2 stops38h 29m
LATAM Airlines
Mon 6/15:25 am
VVI
- HOU
2 stops31h 46m
LATAM Airlines
Deal found 5/11![LATAM Airlines logo]()
$2,321
This Ovago deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:00 am
HOU
- VVI
2 stops21h 35m
LATAM Airlines
Sat 7/255:25 am
VVI
- HOU
2 stops31h 40m
LATAM Airlines
Deal found 5/9![LATAM Airlines logo]()
$2,391
This Priceline deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:06 pm
HOU
- VVI
2 stops38h 29m
LATAM Airlines
Mon 6/15:25 am
VVI
- HOU
2 stops29h 07m
LATAM Airlines
Deal found 5/9![LATAM Airlines logo]()
$2,660
This FlightHub deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:05 am
HOU
- VVI
2 stops44h 51m
LATAM Airlines
Sat 10/105:25 am
VVI
- HOU
2 stops29h 01m
LATAM Airlines
Deal found 5/11![LATAM Airlines logo]()
$3,351
Last-minute flights from Houston to Santa Cruz de la SierraDiscover last-minute flight deals from Houston to Santa Cruz de la Sierra. Data last updated May 11, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Santa Cruz de la Sierra. Data last updated May 11, 2026 and is based on user searches.
This Justfly.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Wed 5/273:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 5/11![Avianca logo]()
$872
This FlightHub deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Fri 5/293:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 5/10![Avianca logo]()
$880
This Avianca deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Fri 5/223:35 am
VVI
- IAH
2 stops37h 35m
Avianca
Deal found 5/8![Avianca logo]()
$901
This FlightHub deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Sat 5/233:35 am
VVI
- IAH
2 stops37h 35m
Avianca
Deal found 5/9![Avianca logo]()
$863
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:17 pm
IAH
- VVI
1 stop18h 43m
Multiple Airlines
Sat 8/88:35 am
VVI
- IAH
2 stops15h 04m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$925
This FlightHub deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:05 pm
IAH
- VVI
2 stops35h 25m
Avianca
Fri 8/73:35 am
VVI
- IAH
2 stops33h 30m
Avianca
Deal found 5/8![Avianca logo]()
$927
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/62:43 pm
IAH
- VVI
2 stops35h 48m
United Airlines
Sat 6/1311:47 am
VVI
- IAH
2 stops45h 48m
United Airlines
Deal found 5/9![United Airlines logo]()
$939
This Trip.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:15 am
IAH
- VVI
3 stops19h 15m
Multiple Airlines
Fri 6/123:35 am
VVI
- IAH
3 stops55h 06m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$948
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:01 am
IAH
- VVI
2 stops39h 37m
United Airlines
Mon 6/1511:47 am
VVI
- IAH
2 stops37h 58m
United Airlines
Deal found 5/9![United Airlines logo]()
$854
This Ovago deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:20 pm
IAH
- VVI
2 stops25h 18m
Copa Airlines
Thu 8/61:12 am
VVI
- IAH
1 stop19h 52m
Copa Airlines
Deal found 5/11![Copa Airlines logo]()
$914
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:03 am
HOU
- VVI
2 stops48h 53m
LATAM Airlines
Mon 6/155:25 am
VVI
- HOU
2 stops41h 18m
LATAM Airlines
Deal found 5/9![LATAM Airlines logo]()
$1,650
This FlightHub deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/192:05 pm
IAH
- VVI
2 stops35h 25m
Avianca
Fri 7/33:35 am
VVI
- IAH
2 stops33h 30m
Avianca
Deal found 5/7![Avianca logo]()
$993
One-way flights from Houston to Santa Cruz de la SierraSearch for one-way flight options from Houston to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
Search for one-way flight options from Houston to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:18 am
IAH
- VVI
3 stops37h 20m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:17 pm
IAH
- VVI
2 stops24h 21m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$444
This Avianca deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:35 am
IAH
- VVI
2 stops17h 55m
Avianca
Deal found 5/9![Avianca logo]()
$659
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:01 pm
HOU
- VVI
3 stops50h 37m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$666
This Ovago deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:59 am
IAH
- VVI
1 stop16h 32m
Copa Airlines
Deal found 5/7![Copa Airlines logo]()
$709
This Avianca deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:35 am
IAH
- VVI
2 stops17h 55m
Avianca
Deal found 5/10![Avianca logo]()
$977
This eDestinos deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:20 pm
HOU
- VVI
2 stops34h 10m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$1,151
Find flight deals from Houston to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 11, 2026.
Round-trip from | $843 (United Airlines) |
|---|---|
One-way from | $407 (Kiwi.com) |
Popular in | November |
Cheapest in | September |
Average price | $862 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Houston to Santa Cruz de la Sierra that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Sun 8/16
10:19 pm-3:35 am
2 stops28h 16m
Santa Cruz de la Sierra Viru Viru Intl
Thu 8/20
11:47 am-8:44 am
2 stops21h 57m
$843
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Mon 9/7
10:19 pm-10:44 pm
2 stops23h 25m
Santa Cruz de la Sierra Viru Viru Intl
Mon 9/21
11:47 am-8:44 am
2 stops21h 57m
$843
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Mon 6/8
8:20 pm-10:38 pm
2 stops25h 18m
Santa Cruz de la Sierra Viru Viru Intl
Thu 8/6
1:12 am-8:04 pm
1 stop19h 52m
$914
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Fri 6/5
2:05 pm-2:30 am
2 stops35h 25m
Santa Cruz de la Sierra Viru Viru Intl
Fri 8/7
3:35 am-12:05 pm
2 stops33h 30m
$927
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Mon 6/8
5:45 pm-2:30 am
2 stops31h 45m
Santa Cruz de la Sierra Viru Viru Intl
Thu 8/6
3:35 am-12:05 pm
2 stops33h 30m
$927
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Sat 6/6
2:43 pm-3:31 am
2 stops35h 48m
Santa Cruz de la Sierra Viru Viru Intl
Sat 6/13
11:47 am-8:35 am
2 stops45h 48m
$939
Quickest round-trip
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Wed 10/7
9:30 am-3:38 am
2 stops17h 08m
Santa Cruz de la Sierra Viru Viru Intl
Mon 10/19
11:47 am-2:17 pm
1 stop27h 30m
$1,058
HoustonSanta Cruz de la Sierra
HOU - VVI
HOUVVI
Houston Hobby
Wed 10/7
5:35 pm-4:35 am
2 stops34h 00m
Santa Cruz de la Sierra Viru Viru Intl
Mon 10/19
5:25 am-9:26 am
2 stops29h 01m
$1,271
HoustonSanta Cruz de la Sierra
HOU - VVI
HOUVVI
Houston Hobby
Mon 6/8
6:03 am-7:56 am
2 stops48h 53m
Santa Cruz de la Sierra Viru Viru Intl
Mon 6/15
5:25 am-9:43 pm
2 stops41h 18m
$1,650
HoustonSanta Cruz de la Sierra
HOU - VVI
HOUVVI
Houston Hobby
Tue 5/26
1:06 pm-4:35 am
2 stops38h 29m
Santa Cruz de la Sierra Viru Viru Intl
Mon 6/1
5:25 am-12:11 pm
2 stops31h 46m
$2,321
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Houston to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Houston with our price prediction graph.
HO1-VVI
IAH-VVI
HOU-VVI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Santa Cruz de la Sierra
HO1-VVI
IAH-VVI
HOU-VVI
What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?
Currently, May is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $673). Flying from Houston to Santa Cruz de la Sierra in January is currently the most expensive (average of $1,177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Santa Cruz de la Sierra
Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated May 11, 2026.
Read reviews from past customers who have flown Copa Airlines,United Airlines, andAvianca from Houston to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Crew
8.1
Comfort
7.4
Entertainment
6.8
Overall
7.5
Food
6.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Boarding
7.8
Crew
8.1
Comfort
7.4
Entertainment
6.8
Overall
7.5
Food
6.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Boarding
7.8
Crew
8.1
Comfort
7.4
Entertainment
6.8
Overall
7.5
Food
6.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Boarding
7.8
Crew
8.1
Comfort
7.4
Entertainment
6.8
Overall
7.5
Food
6.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Related info for your journey
Find useful and relevant information for your journey from Houston to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Houston to Santa Cruz de la Sierra
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Houston to Santa Cruz de la Sierra by cabin class
Find flights from Houston to Santa Cruz de la Sierra, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Houston and Santa Cruz de la Sierra flights
Browse other Houston and Santa Cruz de la Sierra flight options. Last updated on May 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Houston to Santa Cruz de la Sierra
Discover the top 3 airlines that operate flights from Houston to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$709 | Average$1,200 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$741 | Average$1,036 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$748 | Average$874 | FlexibilityNo cancel fee | On-time71% |